Dunja LamatschDunja Lamatsch

 

Present position:

Senior scientist,
Head of Working Group

Research area:

Molecular & Cytogenetic Evolution of Asexual
Aquatic Organisms

Phone:
Fax:
e-mail:

+43 512 507-50204 (office), +43 512 507-50215 (lab)
+43 512 507-50299
dunja.lamatsch@uibk.ac.at


Employment History · Research · Staff · Projects · Teaching · Publications ·
 
Cooperation partners


Employment History

  • September 1, 2012–present:
    Senior scientist at the Research Department for Limnology, Mondsee of the University of Innsbruck and
    Honorary research fellow at the University of Sheffield (Sheffield, UK)
  • 2008–August 31, 2012:
    Senior scientist at the Institute for Limnology in Mondsee and
    Honorary research fellow at the University of Sheffield (Sheffield, UK)
  • (2010–2011):
    maternal leave

  • 2006–2007:
    Marie Curie Postdoctoral Research Fellow , Institute for Animal and Plant Sciences, University of Sheffield (Sheffield, UK ) ·

  • 2005–2006:
    Marie Curie Postdoctoral Research Fellow , Institute of Freshwater Biology, Royal Belgian Institute of Natural Sciences (Brussels, Belgium)

  • 2001–2004:
    Postdoctoral Fellowship
    of the German Research Foundation (Co-PI with M Schartl) at the Institute for Physiological Chemistry I, University of Würzburg (Würzburg, Germany)

  • 1997–2001:
    PhD
    thesis at the Institute for Physiological Chemistry I, University of Würzburg (Würzburg, Germany)

  • 1995–1996:
    Master thesis
    at the Max Planck Institute for Behavioral Physiology Seewiesen (Seewiesen, Germany)


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Research

The paradox of sex remains the queen of problems in evolutionary biology.

Titelblatt: "Der Spiegel" Why SexWaageSexual reproduction is widespread throughout the animal and plant kingdoms, but undercertain conditions remain costly compared to asexual reproduction. Sex creates a wide variety of genotypes on which natural selection can act, but it also breaks up favourable gene combinations. Asexuals have the ability to preserve their genome and to propagate genotypes that have a previous history of success.

In addition, asexuals can reproduce twice as fast as sexuals, because all, rather than half, of their offspring are themselves capable of reproduction. Although asexual reproduction offers several clear short-term advantages, ruling evolutionary theory dictates that the absence of a mechanism for rapid genetic change will direct clones persisting over long time frames into evolutionary dead ends. Several animal and plant groups nevertheless show a large incidence of asexual reproduction and some lineages might have been fully asexual for many millions of years.

Beispiele


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Staff


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Projects

Fate and effect of waste water-borne manufactured nanomaterials in the aquatic food chain (FENOMENO) ERA-NET SIINN (2014-2016) (together with J. Wanzenböck) 
Logo ERA-Net SIINN

PR and media articles for FENOMENO:

- ipoint University of Innsbruck
- SCIENCE APA1

- SCIENCE APA2
- der Standard
- OOE Nachrichten
- Wr. Zeitung
- Tiroler Tageszeitung
- Bezirksrundschau
- wetter.at
- DaNa-Plattform für Nanotechnologie
- Twitter

Molecular Cytogenetics in Teleost Fishes (Coregoninae and Cyprinidae) (2014)-ÖAD project "Bilaterale Aktionen" with Czech Republic


 
EROS in Ostracods: Evolution of Reproduction with Oversized Spermatozoa in Ostracods
(Grant of the German Research Foundation, Co-PI with Dr. Renate Matzke-Karasz, LMU Munich, Germany, 2011-2013)

Giant sperm from Matzke-Karasz (2005)

Giant sperm from Matzke-Karasz (2005)

Recent cypridoidean ostracods (Podocopa) are living mainly in fresh or brackish water environments. They reproduce with filamentous giant sperm, reaching up to ten times the body length of the animal. A common origin of their reproduction with giant sperm is well supported by fossil evidence from the lower Cretaceous, speaking for an evolutionary success of this reproductive mode.

Considering the energetic costs related to production, transport and storage of giant sperm, the question about the advantages stands to reason. Hypotheses that have been put forward for other groups with giant sperm (e.g. copulatory plug, female cryptic choice or zygote nutrition) must be seen as ap-proximations, which are each applicable for at least a few of the regarding taxa. However, none of the existing hypotheses can be satisfactorily assigned to the situation on ostracods.

The present project outline features two hypotheses, of which one, hypothesis B, has been developed in consideration of the special anatomy of ostracods. The hypotheses are: (A) male freshwater ostracods developed giant sperm in order to fill the female receptacles and thus to prevent other males inseminating the female (aim: optimization of fertilization success) and (B) giant sperm help female freshwater ostracods to reduce the sperm transfer rate per time unit (aim: diversification of paternities). A lower sperm transfer rate not only reduces the absolute sperm number per completed insemination; female ostracods potentially have the opportunity to interrupt copulation by closing their valves. A low sperm transfer rate thus allows for an improved control of the number of sperms transferred by actively determining the copulation duration.

Evolution of extraordinary long female sperm ducts and a complex female reproductive system may have caused a selective pressure on males towards the evolution of giant sperm.


Quantifying Individual Fitness with Trojan Sex Chromosomes: an Ultimate Conservation Tool
(Marsden Fund New Zealand #08-UOO-154, Co-PI with Drs. Shinichi Nakagawa & Closs Lokman,
University of Otago, New Zealand, 2010-2012)

Mosquito fish, Gambusia affinis

Mosquito fish, Gambusia affinis

With an alarming decline in biodiversity, conservation biologists have been facing two pressing tasks: 1) protecting and recovering the populations of endangered species, and 2) controlling invasive pest species which threaten native biota. These two tasks usually require different theoretical and/or methodological frameworks.

Recently, the introduction of individuals, carrying ‘Trojan’ sex chromosomes (i.e. hormone-treated individuals whose sex has been reversed from their genotype), into wild populations has been proposed as a potential way of not only exterminating invasive pest species but also of saving endangered species. However, the ecology of individuals carrying Trojan sex chromosomes (i.e. sex-reversed individuals) and their offspring is virtually unknown. Thus, empirical work on the use of Trojan sex chromosomes is urgently required.

We will conduct the first comprehensive investigation quantifying the fitness of sex-reversed individuals and their offspring, using an invasive fish species. We will use three different approaches: morphological, endocrinological and behavioural measurements. This work will extend our knowledge of the intricate relationships among genes, hormones and phenotypic characters.  Importantly, it will explore the feasibility of introducing Trojan individuals into wild populations for conservation proposes. Therefore, our project will ensure that New Zealand remains a front runner in the field of conservation biology.


Gynogenesis as a dispersal strategy
(Funds of the EAWAG, PI with Dr. Jukka Jokela, EAWAG Zürich, Switzerland, Dr. Jouni Taskinen & Manuel Deinhard, University of Jyväskylä, Finland)

The Prussian carp, Carassius gibelio, was introduced to Europe from East Asia, probably as a triploid all-female gynogenetic lineage whose clonal reproduction relies on sperm from related species inducing the asexual egg development. Since its introduction, the Prussian carp invaded most of European fresh water systems and started developing diploid and tetraploid forms, males and sexual modes of reproduction. The mechanism of the observed changes is not well understood. Distribution patterns suggest that the Prussian carp is invasive and displaces its sexual sperm-donor, the European crucian carp (C. carassius).

We investigate the parasite community, ploidy and genetic structure of several European populations of successfully spreading gynogenetic Prussian carp, as well as of their sperm donor, the indigenous Crucian carp. Crossing experiments will give insights into the mechanism of gynogenesis.

Gynogenetic Prussian carp (photo: Jussi Pennanen) Flow cytometric measurement of genome size

Gynogenetic Prussian carp (photo: Jussi Pennanen)                   Flow cytometric measurement of genome size


Paternal introgression in the sperm-dependent parthenogen Poecilia formosa

Amazon molly

Amazon molly

The Amazon molly, Poecilia formosa, is an all-female species that reproduces gynogenetically: it produces unreduced eggs but needs sperm from a closely related sexual species to trigger the onset of embryonic development. Usually, the male genetic material is excluded from the oocyte and does not contribute to the offspring (clonal reproduction).

In very rare cases, however, this exclusion mechanism fails and the male genome fertilizes the egg leading to triploid individuals. We are interested in this form of paternal introgression because polyploidization is thought to drive evolution and speciation as it provides plenty of genetic material for differentiation. This additional genetic material might be especially valuable to P. formosa that - as a clonal organism - should suffer from an overall low genotypic variability and the accumulation of deleterious mutations.

We found, however, that the triploid clones of P. formosa have a low genetic variability and are most likely of monophyletic origin. We discovered a second level of paternal introgression when we recently found the first tetraploid P. formosa. Most likely it resulted from the fertilization of a triploid egg. We hypothesize that triploids could be important stepping stones to create tetraploids that (by segregation of chromosome sets) might have an important role in creating genotypic variation in the diploid lines of P. formosa. This would explain why in the field diploid P. formosa show a high clonal diversity.

In addition, diploids show another type of paternal introgression: supernumerary microchromosomes which might also contribute to high clonal diversity in diploids.


From Sex to Asex: A case study on interactions between sexual and asexual reproduction in a non-marine ostracod (Link)

Non-marine ostracod, Eucypris virens

Non-marine ostracod, Eucypris virens

An elevation in ploidy often accompanies the transition from sexual to asexual mode of reproduction, yet the ecological and evolutionary importance of ploidy in the maintenance of parthenogenetic populations is still not clear. We survey association of ploidy and geographic distribution of asexual and sexual European Eucypris virens and analyse its patterns in the perspective of lineage origin.

This freshwater ostracod has a wide geographic distribution and was found as diploid sexual, diploid asexual and triploid asexual. There have been repeated origins of both, diploid asexual and triploid lineages, and these share sexual ancestors. As a consequence of the exceptional cryptic divergence between sexual populations, asexual lineages come in a great variety of genetic backgrounds. Northern as well as southern sites are often occupied by clones of multiple origins, there is, however, a clear dominance of triploid asexuals in northern Europe. The scarce distribution of diploid asexuals despite common ancestry with triploid asexuals thus confirm the view that wider geographic distribution of triploids is rather due to elevated ploidy, which may be of hybrid origin, than asexuality.


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Teaching

Bachelor theses

  • Lukas Ajchler (2015)
  • Andreas Meindl (2015)
  • Marlene Oefele (2015)
  • Lisa Strasser (2012)
  • Irene Riedl (2012)
  • Stefan Holl (2011)
  • Manuel Deinhardt (2009)
  • Michaela Zopf (2009)

Master theses

  • Manuel Deinhardt (2013)

2018 (SS)

  • Wahlmodul Genomevolution (BSc)

2017 (SS)

  • Wahlmodul Genomevolution (BSc)

2016/2017 (WS)

  • Frauen in der Biologie (SE)

2017 (SS)

  • Wahlmodul Genomevolution (BSc)

2015 (SS)

  • Wahlmodul Genomevolution (BSc)
  • Geschichte der Biologie (SE 743502)

2013/2014 (WS)

  • Genderforschung in der Biologie (VO 743500) - feedback
  • Frauen in der Biologie (SE 743501)

2013 (SS)

  • Natur als Politikum ( VO 743503)

2008-2011

  • „Basic molecular laboratory techniques“ (experimental laboratory course)
  • „Basic cytogenetic laboratory techniques“ (experimental laboratory course)

2007

  • Workshop on “Flow Cytometry” (Aquatic Ecology, EAWAG, Duebendorf/Switzerland)

2006

  • Workshop on “Basic molecular laboratory & population genetics techniques” (Lecture with exercises)
    (Department of Animal & Plant Sciences, University of Sheffield, UK)

2001-2004

  • “Biochemistry for medical students” (lecture with exercises)
    (Physiological Chemistry I, University of Würzburg, Germany)
  • Prüfer für den mündlichen Teil der Ärztlichen Vorprüfung (Biochemie)

1997-2001

  • “Biochemistry for medical students” (experimental laboratory course)
    (Physiological Chemistry I, University of Würzburg, Germany)

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Publications

submitted

  • Senior A.M., Lokman P.M., Lamatsch D.K.,  Ling N., Adolfsson S., Closs G.P., Nakagawa S.: Endocrine-disrupting chemicals and ensuing sex-reversal affect morphology and behaviour in Gambusia affinis.

2016

  • Senior A.M., Lim J.N., Adolfsson S., Lamatsch D.K., Nakagawa S. (2016). Condition and reproductive investment in the western mosquitofish (Gambusia affinis): little evidence for condition-dependent sex biased investment. Biological Journal of the Linnean Society 119: 430-435  DOI: 10.1111/bij.12813

2015

  • Lamatsch D.K., Adolfsson S., Senior A.M., Christiansen G., Pichler M., Ozaki Y., Smeds L., Schartl M., Nakagawa S. (2015). A transcriptome derived sex –specific marker in the invasive Western mosquitofish Gambusia affinis. PLoSOne 2015 Feb 23;10(2):e0118214. doi: 10.1371/journal.pone.0118214.

2014

  • Schlupp I., Lamatsch D.K., Teege K., Parzefall J. (2014): Food finding ability in several molly species (Poecilia spp.), including the unisexual Amazon molly. Bulletin of Fish Biology 14 (in press).

2013

  • Schmit O., Bode S.N.S., Camacho A., Horne D.J., Lamatsch D.K., Martens K., Martins M.J., Namiotko T., Rossetti G., Rueda-Sevilla J., Schön I., Vandekerkhove J., Mesquita-Joanes F. (2013). Linking present environment and reproductive modes segregation (Geographic Parthenogenesis) in Eucypris virens (Crustacea: Ostracoda). Journal of Biogeography 40:2396–2408

  • Stöck M., Lamatsch D.K. (2013). Why Comparing Polyploidy Research in Animals and Plants. Cytogenet Genome Res 140:75-78 DOI: 10.1159/000353304
  • Book: Trends in Polyploidy Research in Animals and Plants (M. Stöck, DK Lamatsch, eds.) (2013).  Cytogenetic and Genome Research themed issue 140 (2-4) 2013
    Dunja Lamatsch

  • Rylková K., Kalous L., Bohlen J., Lamatsch D.K., Petrtýl M. (2013). Phylogeny and biogeographic history of the cyprinid fish genus Carassius (Teleostei: Cyprinidae) with focus on natural and anthropogenic arrivals in Europe. Aquaculture 380-383: 13-20.

2011

  • Adolfsson S., Lamatsch D.K., Paczesniak D., Michalakis Y., Martens K., Schön I., Butlin R. K., Jokela J. (2011). Mitochondrial cluster-specific genome size variability among sexual and asexual lineages of the ostracod Eucypris virens species group. Joannea Geol. Paläont. 11: 9-12

  • Lamatsch D.K., Trifonov V., Schories S., Epplen J.T., Schmid M., Schartl M. (2011). Isolation of a cancer-associated microchromosome in the sperm-dependent parthenogen Poecilia formosa. Cytogenetics and Genome Research doi: 10.1159/000331271

  • Bruvo R., Adolfsson S., Symonova R., Lamatsch D.K., Schön I., Jokela J., Butlin R.K., Müller, S. (2011). Few parasites, and no evidence for Wolbachia infections in a freshwater ostracod inhabiting temporary ponds. Biological Journal of the Linnean Society 102: 208–216. doi: 10.1111/j.1095-8312.2010.01556.x PDF

2010

  • Stöck M., Ustinova J., Lamatsch D.K., Schartl M., Perrin N., Moritz C. (2010). A vertebrate reproductive system involving three ploidy levels: Hybrid origin of triploids in a contact zone of diploid and tetraploid Palearctic green toads (Bufo viridis subgroup). Evolution 64: 944-959. doi: 10.1111/j.1558-5646.2009.00876.x http://onlinelibrary.wiley.com/doi/10.1111/j.1558-5646.2009.00876.x/full

  • Adolfsson S., Michalakis Y., Paczesniak D., Bode S.N.S., Butlin R.K., Lamatsch D.K., Martins M.J.F., Schmit O., Vandekerkhove J., Jokela J. (2010). Evaluation of elevated ploidy and asexual reproduction as alternative explanations for geographic parthenogenesis in Eucypris virens ostracods. Evolution. 64: 986-997. doi:10.1111/j.1558-5646.2009.00872.x PDF

  • Bode S.N.S., Adolfsson S., Lamatsch D.K., Martins M.J.F., Schmit O., Vandekerkhove J., Mezquita F., Namiotko T., Rossetti G., Schön I., Butlin R.K., Martens K. (2010): Exceptional cryptic diversity and multiple origins of parthenogenesis in a freshwater ostracod. Molecular Phylogenetics and Evolution 54: 542–552. doi:10.1016/j.ympev.2009.08.022 PDF

  • Lamatsch D.K. , Stöck M., Fuchs R., Döbler M., Wacker R., Parzefall J., Schlupp I., Schartl M. (2010). Morphology, testes development and behaviour of unusual triploid males in microchromosome-carrying clones of Poecilia formosa. Journal of Fish Biology 77: 1459–1487. doi: 10.1111/j.1095-8649.2010.02766.x Abstract

  • Sandberger L., Feldhaar H., Lampert K.P., Lamatsch D.K., Rodel M.O. (2010). Small, specialised and highly mobile? The tree-hole breeding frog, Phrynobatrachus guineensis, lacks fine-scale population structure. African Journal of Herpetology 59: 79-94. doi: 10.1080/04416651003788619 PDF

2009

  • Lamatsch D.K., Stöck M. (2009). Sperm-dependent parthenogenesis and hybridogenesis in teleost fishes. In: Lost sex! The Evolutionary Biology of Parthenogenesis (eds. I. Schön, K. Martens & P. Van Dijk), pp. 399-432 Springer, Dordrecht. doi: 10.1007/978-90-481-2770-2_19 Abstract

2008

  • Schön I., Lamatsch D.K., Martens K. (2008). Lessons to Learn from Ancient Asexuals. In: Genome Dynamics & Stability, Vol. 3 (eds. D. Lankenau & R. Egel) Springer Berlin / Heidelberg. Link

  • Lamatsch D.K., Fischer P., Geiger M., Lampert K.P., Schlupp I., Schartl M. (2008). Diploid Amazon mollies (P. formosa) show a higher fitness than triploids in clonal competition experiments. Evolutionary Ecology 23: 687-697. doi:10.1007/s10682-008-9264-2

  • Loewe L., Lamatsch, D.K. (2008). Muller´s ratchet may threaten the Amazon molly and other ancient asexuals. BMC Evolutionary biology 8: 88-108. doi:10.1186/1471-2148-8-88

  • Lamatsch, D.K., Lampert, K.P., Fischer, P., Schartl, M. (2008). A tetraploid Amazon molly, Poecilia formosa. Journal of Heredity 99: 223-226.. doi:10.1093/jhered/esm102

2007

  • Lamatsch D.K., Lampert K.P., Fischer P., Epplen J.T., Nanda I., Schmid M., Schartl M. (2007). Automictic reproduction in interspecific hybrids of poeciliid fish, Current Biology 17: 1948-1953. doi:10.1016/j.cub.2007.09.064

  • Nanda I., Schlupp I., Lamatsch D.K., Lampert K.P., Schmid M., Schartl M. (2007). Stable inheritance of host species-derived microchromosomes in the gynogenetic fish, Poecilia formosa. Genetics 177: 917-926. doi:10.1534/genetics.107.076893

  • Schories S., Lampert P., Lamatsch D.K., García de León F.J., Schartl M. (2007). Analysis of a possible independent origin of triploid P. formosa outside of the Río Purificación river system. Frontiers in Zoology 4: 13. doi:10.1186/1742-9994-4-13

  • Janko K., Bohlen J., Lamatsch D.K., Flajshans M., Epplen J.T., Rab P., Kotlik P., Slechtova V. (2007). The gynogenetic reproduction of diploid and triploid hybrid spined loaches (Cobitis: Teleostei), and their ability to establish successful clonal lineages-on the evolution of polyploidy in asexual vertebrates. GENETICA 13: 185-194. doi:10.1007/s10709-006-9130-5

2006

  • Sirviö A., Gadau J., Rueppell O., Lamatsch D.K., Boomsma J.J., Pamilo P., Page R.E. Jr. (2006). High recombination frequency creates genotypic diversity in colonies of the leaf-cutting ant Acromyrmex echinatior. JOURNAL OF EVOLUTIONARY BIOLOGY 19: 1475-1485. doi:10.1111/j.1420-9101.2006.01131.x

  • Lampert K.P., Lamatsch D.K., Schories S., Hopf A., Garcia de Leon F.J., Schartl M. (2006). Microsatellites for the gynogenetic Amazon molly, P. formosa: useful tools for detection of mutation rate, ploidy determination and overall genetic diversity. JOURNAL OF GENETICS 85: 67-71. PDF

2005

  • Stöck M., Steinlein C., Lamatsch D.K., Schartl M., Schmid M. (2005). Multiple origin of tetraploid taxa in the Eurasian Bufo viridis subgroup. GENETICA 124: 255-272. PDF

  • Lamatsch D.K., Lampert K.P., Epplen J.T., Schartl M. (2005). Evidence for a monophyletic origin of the triploid clones of the Amazon molly, Poecilia formosa. EVOLUTION 59: 881–889. doi:10.1111/j.0014-3820.2005.tb01761.x

2004

  • Lamatsch D.K., Nanda I., Schlupp I., Epplen J.T., Schmid M., Schartl M. (2004). Distribution and stability of supernumerary microchromosomes in natural populations of the Amazon molly, Poecilia formosa. CYTOGENETICS AND GENOME RESEARCH 106: 189-194. doi: 10.1159/000079286

2003

  • Ziegler C., Lamatsch D.K., Schartl M., Schmid M. (2003). The giant B chromosomes of the cyprinid fish Alburnus alburnus harbours a specific retrotransposon repetitive sequence. Chromosome Res 11:23-35.

2002

  1. Stöck M., Lamatsch D.K. (2002). Triploide Wirbeltiere: Wege aus der Unfruchtbarkeit oder Eingeschlechtigkeit. Naturwissenschaftliche Rundschau 55 (7): 349-358.

  2. Stöck M., Lamatsch D.K., Steinlein C., Epplen J.T., Grosse W.R., Hock R., Klapperstück T., Lampert K., Scheer U., Schmid M., Schartl, M. (2002). Discovery of a bisexually reproducing all-triploid vertebrate. Nature Genetics 30: 325-328. doi:10.1038/ng839, PDF

  3. Lamatsch D.K., Schmid M., Schartl M. (2002). Somatic mosaic of the gynogenetic Amazon molly, P. formosa (Poeciliidae, Teleostei). Journal of Fish Biology 60: 1417-1422. doi:10.1111/j.1095-8649.2002.tb02436.x

2000

  • Lamatsch D.K., Nanda I., Epplen J.T., Schmid M., Schartl M. (2000). Unusual triploid males in a microchromosome carrying clone of the Amazon molly, Poecilia formosa. Cytogenetics and Cell Genetics 91: 148-156.

  • Lamatsch D.K., Steinlein C., Schmid M., Schartl M. (2000). Non-invasive determination of genome size and ploidy level in fishes by flow cytometry: detection of triploid Poecilia formosa. Cytometry 39: 91-95. Link

1998

  • Schlupp I., Nanda I., Döbler M., Lamatsch D.K., Epplen J.T., Parzefall J., Schmid M., Schartl M. (1998). Dispensable and indispensable genes in an ameiotic fish, the Amazon molly Poecilia formosa. Cytogenetics and Cell Genetics 80: 193-198.

  • Lamatsch D.K., Sharbel T.F., Martin R., Bock C. (1998). A drop technique for flatworm chromosome preparation for light microscopy and high-resolution scanning electron microscopy. Chromosome Research 6: 654-656. Link


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Cooperation partners


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