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 ORCIDiD 0000-0002-2177-983X

Zeindl R, Unterhauser J, Röck MEidelpes R, Führer S, Tollinger M*.

Structural characterization of food allergens by nuclear magnetic resonance spectroscopy.

Meth Mol Biol 2024 (2717) 159-173.

doi: 10.1007/978-1-0716-3453-0

Unterhauser J, Ahammer L, Rainer T, Eidelpes R, Führer S, Nothegger B, Covaciu CE, Cova V, Kamenik AS, Liedl KR, Müller T, Breuker K, Eisendle K, Reider N, Letschka T*, Tollinger M*.

Covalent polyphenol modification of a reactive cysteine in the major apple allergen Mal d 1.

Food Chemistry 2023 (410) 135374. (open access)

doi: 10.1016/j.foodchem.2022.135374 

Kim HJ, Black M, Edwards R, Peillard-Fiorente F, Panigrahi R, Klingler D, Eidelpes R, Zeindl R, Peng S, Su J, Omar AR, MacMillan A, Kreutz C, Tollinger M, Charpentier X, Attaiech L*, Glover JNM*.

Structural basis for recognition of transcriptional terminator structures by ProQ/FinO domain RNA chaperones.

Nat Comm 2022 (13) 1776. (open access)

doi: 10.1038/s41467-022-34875-5

Ahammer L, Unterhauser J, Eidelpes R, Meisenbichler C, Nothegger B, Covaciu CE, Cova V, Kamenik AS, Liedl KR, Breuker K, Eisendle K, Reider N, Letschka T, Tollinger M*.

Ascorbylation of a reactive cysteine in the major apple allergen Mal d 1.

Foods 2022 (11) 2953. (open access)

doi: 10.3390/foods11192953

Klingler D, Huber M, Tollinger M, Kreutz C*.

Rapid and reliable RNA resonance assignment by combining chemical and enzymatic stable isotope labeling.

J Magn Reson Open 2022 (12-13) 100077. (open access)

doi: 10.1016/j.jmro.2022.100077

Führer S, Unterhauser J, Zeindl R, Eidelpes R, Fernández-Quintero ML, Liedl KR, Tollinger M*.

The structural flexibility of PR-10 food allergens.

Int J Mol Sci 2022 (23) 8252. (open access)

doi: 10.3390/ ijms23158252

Rainer T, Egger A-S, Zeindl R, Tollinger M, Kwiatkowski M; Müller, T*.

3D Printed high pressure resistant immobilized enzyme microreactor (µIMER) for protein analysis.

Anal Chem 2022 (94): 8580-8587. (open access)

doi: 10.1021/acs.analchem.1c05232

Winkler D, Dietrich V, Griesser C, Shakibi-Nia N, Wernig E-M, Tollinger M, Kunze-Liebhäuser J*.

Formic acid reduction and CO2 activation at Mo2C – the important role of surface oxide.

Electrochem Sci Adv 2022 (2): e2100130. (open access)

doi: 10.1002/elsa.202100130

Eidelpes R, Hofer F, Röck M, Führer S, Kamenik A, Liedl KR, Tollinger M*.

Structure and zeatin binding of the peach allergen Pru p 1.

J Agricult Food Chem 2021 (69): 8120-8129. (open access)

doi: 10.1021/acs.jafc.1c01876

Oettl S, Bosello M, Marschall K, Gallmetzer A, Reyes-Dominguez Y, Kreutz C, Tollinger M, Robatscher P, Oberhuber M*.

(3ξ,4ξ,5ξ,6ξ,7ξ,11ξ)-3,6-dihydroxy-8-oxo-9-eremophilene- 12-oic acid, a new phytotoxin of alternaria alternata ssp. tenuissima isolates associated with fruit spots on apple (Malus × domestica Borkh.).

J Agricult Food Chem 2021 (69): 14445-14448. (open access)

doi: 10.1021/acs.jafc.1c02847

Rainer T, Eidelpes R, Tollinger M, Müller T*.

Microdroplet mass spectrometry enables extremely accelerated pepsin digestion of proteins.

J Am Soc Mass Spectrom 2021 (32): 1841-1845. (open access)

doi: 10.1021/jasms.1c00126

Zeindl R, Tollinger M*.

NMR resonance assignments of the PR-10 allergens Act c 8 and Act d 8 from golden and green kiwifruit.

Biomol NMR Assign 2021 (15): 367-371. (open access)

doi: 10.1007/s12104-021-10031-w 

Führer S, Kamenik AS, Zeindl R, Nothegger B, Hofer F, Reider N, Liedl KR, Tollinger M*.

Inverse relation between structural flexibility and IgE reactivity of Cor a 1 hazelnut allergens.

Sci Rep 2021 (11): 4173. (open access)

doi: 10.1038/s41598-021-83705-z

Mateos B; Bernardo-Seisdedos G; Dietrich V; Zalba N; Ortega G; Peccati F; Jiménez-Osés G; Konrat R; Tollinger M, Millet O*. 

Cosolute modulation of protein oligomerization reactions in the homeostatic timescale.

Biophys J 2021 (120): 2067-2077. (open access)

doi: 10.1016/j.bpj.2021.03.020

Nothegger B, Reider N, Covaciu CE, Cova V, Ahammer LEidelpes R, Unterhauser J, Platzgummer S, Raffeiner, E, Tollinger M, Letschka T,  Eisendle K*. 

Oral immunotherapy with apples: results of a phase II clinical pilot study.

Immun Inflamm Dis 2021 (9): 503-511. (open access)

doi: 10.1002/iid3.410

Eidelpes R, Kim HJ, Glover JNM, Tollinger M*.

NMR resonance assignments of the FinO-domain of the RNA chaperone RocC.

Biomol NMR Assign 2021 (15): 61-64. (open access)

doi: 10.1007/s12104-020-09983-2

Winter P, Stubenvoll S, Scheiblhofer S, Joubert IA, Strasser L, Briganser C, Soh WT, Hofer F, Kamenik AS, Dietrich V, Michelini S, Laimer J, Lackner P, Horejs-Hoeck J, Tollinger M, Liedl KR, Brandstetter J, Huber CG, Weiss R*. 

In silico design of Phl p 6 variants with altered folding stability significantly impacts antigen processing, immunogenicity and immune polarization.

Front Immunol 2020 (11): 1824. (open access)

doi: 10.3389/fimmu.2020.01824 

Nothegger B, Reider N, Covaciu CE, Eidelpes R, Unterhauser J, Ahammer L, Tollinger M, Cova V, Letschka T, Platzgummer S, Eisendle K*. 

Allergen-specific immunotherapy with apples: Selected cultivars could be a promising tool for birch pollen allergy.

J Eur Acad Derma­tol Vene­rol 2020 (34): 1286-1292. (open access)

doi: 10.1111/jdv.16201

Discussed in: Bergmann K.-C.: Journal of the European Academy of Derma­tology and Vene­rology 2020 (34): 1130.

Führer S, Zeindl R, Tollinger M*.

NMR resonance assignments of the four isoforms of the hazelnut allergen Cor a 1.04.

Biomol NMR Assign 2020 (14): 45-49. (open access)

doi: 10.1007/s12104-019-09918-6

Salcher S, Spoden G, Hagenbuchner J, Führer S, Kaserer T, Tollinger M, Huber-Cantonati P, Gruber T, Schuster D, Gust R, Zwierzina H, Müller T, Kiechl Kohlendorfer U, Ausserlechner M*, Obexer P*.

A drug library screen identifies Carbenoxolone as novel FOXO inhibitor which overcomes FOXO3-mediated chemoprotection in high-stage neuroblastoma.

Oncogene 2020 (39): 1080-1097. (open access)

doi: 10.1038/s41388-019-1044-7

Führer S, Tollinger M, Dunzendorfer-Matt T*.

Pathogenic mutations associated with Legius syndrome modify the Spred1 surface and are iInvolved in direct binding to the Ras inactivator Neurofibromin.

J Mol Biol 2019 (431): 3889-3899.

doi: 10.1016/j.jmb.2019.07.038

Hofer F, Dietrich V, Kamenik A, Tollinger M, Liedl KR*.

pH-Dependent protonation of the Phl p 6 pollen allergen studied by NMR and cpH-aMD.

J Chem Theor Comput 2019 (15): 5716-5726. (open access)

doi: 10.1021/acs.jctc.9b00540

Plangger R, Juen AR, Hoernes TP, Nußbaumer F, Kremser J, Strebitzer S, Klingler D, Erharter K, Tollinger M, Erlacher MD, Kreutz C*.

Branch site bulge conformationas in domain 6 determine functional sugar puckers in group II intron splicing.

Nucleic Acids Res 2019 (21): 11430-11440.  (open access)

doi: 10.1093/nar/gkz965

Führer S, Trimmel S,  Breuker K, Tollinger M*.

NMR resonance assignments of the pathogenesis-related peach allergen Pru p 1.0101.

Biomol NMR Assign 2019 (13): 127-130. (open access)

doi: 10.1007/s12104-018-9864-x

Strebitzer E, Nußbaumer F, Kremser J, Tollinger M, Kreutz C*.

Studying sparsely populated conformational states in RNA combining chemical synthesis and solution NMR spectroscopy.

Methods 2018 (148): 39-47. (open access)

doi: 10.1016/j.ymeth.2018.05.007

Strebitzer E, Rangadurai A, Plangger R, Kremser J, Juen MA, Tollinger M, Al-Hashimi H, Kreutz C*.

5-oxyacetic modification destabilizes double helical stem structures and favors anionic Watson-Crick like cmo5U-G base pairs.

Chem Eur J 2018 (24): 18903-18906. (open access)

doi: 10.1002/chem.201805077

Führer S, Ahammer L, Ausserbichler A, Scheffzek K, Dunzendorfer-Matt T*, Tollinger M*.

NMR resonance assignments of the EVH1 domain of Neurofibromin's recruitment factor Spred1.

Biomol NMR Assign 2017 (11): 305-308. (open access)

doi: 10.1007/s12104-017-9768-1

Grutsch S, Fuchs JE, Ahammer L,  Kamenik AS, Liedl KR*, Tollinger M*.

Conformational flexibility differentiates naturally occurring Bet v 1 isoforms.

Int J Mol Sci 2017 (18): 1192. (open access)

doi: 10.3390/ijms18061192

Ahammer L, Grutsch S, Kamenik AS, Liedl KR, Tollinger M*.

Structure of the major apple allergen Mal d 1.

J Agricult Food Chem 2017 (65): 1606-1612. (open access)

doi: 10.1021/acs.jafc.6b05752

Ahammer L, Grutsch S, Wallner M, Ferreira F, Tollinger M*.

NMR resonance assignments of a hypoallergenic isoform of the major birch pollen allergen Bet v 1.

Biomol NMR Assign 2017 (11): 231-234. (open access)

doi: 10.1007/s12104-017-9754-7

Nussbaumer F, Juen M, Gasser C, Kremser J, Mueller T, Tollinger M, Kreutz CK*.

Synthesis and incorporation of 13C-labeled DNA building blocks to probe structural dynamics of DNA by NMR.

Nucleic Acids Res 2017 (45): 9178-9192. (open access)

doi: 10.1002/nar/gkx592

Moschen T, Grutsch S, Juen, MA, Wunderlich CH, Kreutz C*, Tollinger M*.

Measurement of ligand-target residence times by 1H relaxation dispersion NMR spectroscopy.

J Med Chem 2016 (59): 10788-10793. (open access)

doi: 10.1021/acs.jmedchem.6b01110

Juen MA, Wunderlich CH, Nussbaumer F, Tollinger M, Kontaxis G, Konrat R, Hansen DF*, Kreutz CK*.

Excited states of nucleic acids probed by proton relaxation dispersion NMR spectroscopy.

Angew Chem Intl Ed Engl 2016 (55): 12008-12012. (open access)

doi: 10.1002/anie.201605870

Ahammer L, Grutsch STollinger M*.

NMR resonance assignments of the major apple allergen Mal d 1.

Biomol NMR Assign 2016 (10): 287-290. (open access)

doi: 10.1007/s12104-016-9685-8

Grutsch SBrüschweiler STollinger M*.

NMR methods to study dynamic allostery.

PLoS Comput Biol 2016 (12): e1004620. (open access)

doi: 10.1371/journal.pcbi.1004620

Machado Y, Freier R, Scheiblhofer S, Thalhamer T, Mayr M, Briza P, Grutsch SAhammer L, Fuchs J, Wallnöfer H, Isakovic A, Kohlbauer V, Hinterholzer A, Steiner M, Danzer M, Horejs-Hoeck J, Ferreira F, Liedl KR, Tollinger M, Lackner P, Johnson CM, Brandstetter H, Thalhamer J & Weiss R*.

Fold-stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen.

Journal of Allergy and Clinical Immunology 2016 (137): 1525-1534. (open access)

doi: 10.1016/j.jaci.2015.09.026 

Kaderavek P, Grutsch S, Salvi N, Tollinger M, Zidek L, Bodenhausen G & Ferrage F*.

Cross-correlated relaxation measurements under adiabatic sweeps: determination of local order in proteins.

J Biomol NMR 2015 (63): 353-365. (open access)

doi: 10.1007/s10858-015-9994-8

Moschen T, Wunderlich C, Kreutz C, Tollinger M*.

NMR resonance assignments of the archaeal ribosomal protein L7Ae in the apo form and bound to a 25 nt RNA.

Biomol NMR Assign 2015 (9): 177-180. (open access)

doi: 10.1007/s12104-014-9569-8

Pummer BG*, Budke C, Augustin-Bauditz S, Niedermeier D, Felgitsch L, Kampf CJ, Huber RG, Liedl KR, Loerting T, Moschen T, Schauperl M, Tollinger M, Morris CE, Wex H, Grothe H, Pöschl U, Koop T, Fröhlich-Nowoisky J.

Ice nucleation by water-soluble macromolecules.

Athmos Chem Phys 2015 (15): 4077-4091. (open access)

doi: 10.5194/acp-15-4077-2015

Moschen T, Wunderlich CH, Spitzer R, Levic J, Micura R, Tollinger M*, Kreutz C*.

Ligand-detected relaxation dispersion NMR spectroscopy: dynamics of preQ1-RNA binding.

Angew Chem Intl Ed Engl 2015 (54): 560-563.

doi: 10.1002/anie.201409779

Grutsch S, Fuchs JE, Freier R, Kofler S, Bibi M, Asam C, Wallner M, Ferreira F, Brandstetter H, Liedl KR, Tollinger M*.

Ligand binding modulates structural dynamics and compactness of the major birch pollen allergen Bet v 1.0101.

Biophys J 2014 (107): 2963-2972. (open access)

doi: 10.1016/j.bpj.2014.10.062

Morin S, Linnet TE, Lescanne M, Schanda P, Thompson G, Tollinger M, Teilum K, Gagne S, Marion D, Griesinger C, Blackledge M, d´Auvergne E*.

Relax: the analysis of biomolecular kinetics and thermodynamics using NMR relaxation dispersion data.

Bioinformatics 2014 (30): 2219-2220. (open access)

doi: 10.1093/bioinformatics/btu166

Moschen TTollinger M*.

A kinetic study of domain swapping in Protein L.

Phys Chem Chem Phys 2014 (16): 6383-6390.

doi: 10.1039/C3CP54126F

Palazzesi F, Barducci A, Tollinger M, Parrinello M*.

The allosteric communication pathways in the KIX domain.

Proc Natl Acad Sci USA 2013 (110): 14237-14242. (open access)

doi: 10.1073/pnas.1313548110

Brüschweiler S, Konrat R, Tollinger M*.

Allosteric communication in the KIX domain proceeds through dynamic re-packing of the hydrophobic core.

ACS Chem Biol 2013 (8): 1600-1610. (open access)

doi: 10.1021/cb4002188

Tollinger M, Sivertsen A, Meier B, Ernst M, Schanda P*.

Site-resolved measurement of microsecond to millisecond conformational-exchange processes in proteins by solid-state NMR spectroscopy.

J Am Chem Soc 2012 (134): 14800-14807. (open access)

doi: 10.1021/ja303591y

Wunderlich C, Spitzer R, Santner T, Fauster K, Tollinger M, Kreutz C*.

Synthesis of 6-13C-pyrimidine nucleotides as spin labels for RNA dynamics.

J Am Chem Soc 2012 (134): 7558-7569.


Kloiber K, Spitzer R, Grutsch S, Kreutz C, Tollinger M*.

Longitudinal exchange: an alternative strategy towards quantification of dynamics parameters in ZZ exchange spectroscopy.

J Biomol NMR 2011 (51): 123-129.

doi: 10.1007/s10858-011-9547-8

Spitzer R, Kloiber K, Tollinger M, Kreutz C*.

Kinetics of DNA refolding via longitudinal exchange NMR spectroscopy.

ChemBioChem 2011 (12): 2007-2010.

doi: 10.1002/cbic.201100318

Auer R, Tollinger M, Kuprov I, Konrat R, Kloiber K*.

Mathematical treatment of adiabatic fast passage pulses for the computation of nuclear spin relaxation rates in proteins with conformational exchange.

J Biomol NMR 2011 (51): 35-47. (open access)

doi: 10.1007/s10858-011-9539-8

Coudevylle N, Geist L, Hoetzinger M, Tollinger M, Konrat R*.

Siderocalin Q83 exhibits differential slow dynamics upon ligand binding.

J Biomol NMR 2011 (51): 83-88.

doi: 10.1007/s10858-011-9543-z

Kloiber K, Spitzer R, Tollinger M, Konrat R, Kreutz C*.

Probing RNA dynamics via longitudinal exchange and CPMG relaxation dispersion NMR spectroscopy using a sensitive 13C-methyl label.

Nucleic Acids Res 2011 (39): 4340-4351. (open access)

doi: 10.1093/nar/gkq1361

Breuker K*, Brüschweiler STollinger M.

Electrostatic stabilization of native protein structure in the gas phase. 

Angew Chem Intl Ed Engl 2011 (50): 873-877. (open access)

doi: 10.1002/ange.201005112

Discussed in: Barran PE: Angew Chem Intl Ed Engl 2011 (50): 3120-3122.

Brüschweiler S, Schanda P, Kloiber K, Brutscher B, Kontaxis G, Konrat R, Tollinger M*.

Direct observation of the dynamic process underlying allosteric signal transmission. 

J Am Chem Soc 2009 (131): 3063-3068.

doi: 10.1021/ja809947w

Schedlbauer A, Coudevylle N, Auer R, Kloiber K, Tollinger M, Konrat R*.

Auto-correlation analysis of NOESY data provides residue compactness for folded and unfolded proteins. 

J Am Chem Soc 2009 (131): 6038-6039.

doi: 10.1021/ja8074067

Schedlbauer A, Auer R, Ledolter K, Tollinger M, Kloiber K, Lichtenecker R, Rüdisser S, Hommel U, Schmid W, Konrat R, Kontaxis G*.

Direct methods and residue type specific isotope labeling in NMR structure determination and model-driven sequential assignment. 

J Biomol NMR 2008 (42): 111-127.

doi: 10.1007/s10858-008-9268-9

Schanda P, Brutscher B, Konrat R, Tollinger M*.

Folding of the KIX domain: characterization of the equilibrium analog of a folding intermediate using 15N/13C relaxation dispersion and fast 1H/2H amide exchange NMR spectroscopy. 

J Mol Biol 2008 (380): 726-741.

doi: 10.1016/j.jmb.2008.05.040

Marsh JA, Baker JM, Tollinger M, Forman-Kay JD*.

Calculation of residual dipolar couplings from disordered state ensembles using local alignment.

J Am Chem Soc 2008 (130): 7804-7805.

doi: 10.1021/ja802220c

Tollinger M*, Kloiber K, Agoston B, Dorigoni C, Lichtenecker R, Schmid W, Konrat R.

An isolated helix persists in a sparsely populated form of KIX under native conditions.

Biochemistry 2006 (45): 8885-8893.

doi: 10.1021/bi0607305

Tollinger M, Neale C, Kay LE, Forman-Kay JD*.

Characterization of the hydrodynamic properties of the folding transition state of an SH3 domain by magnetization transfer NMR spectroscopy.

Biochemistry 2006 (45): 6434-6445.

doi: 10.1021/bi060268o

Tollinger M*, Kay LE, Forman-Kay JD.

Measuring pK(a) values in protein folding transition state ensembles by NMR spectroscopy.

J Am Chem Soc 2005 (127): 8904-8905.

doi: 10.1021/ja051942c

Bezsonova I, Singer A, Choy WY, Tollinger M, Forman-Kay JD*.

Structural comparison of the unstable drkN SH3 domain and a stable mutant.

Biochemistry 2005 (44): 15550-15560.

doi: 10.1021/bi0512795

Tollinger M, Crowhurst KA, Kay LE, Forman-Kay JD*.

Site-specific contributions to the pH dependence of protein stability.

Proc Natl Acad Sci USA 2003 (100): 4545-4550.

doi: 10.1073/pnas.0736600100

Crowhurst KA, Tollinger M, Forman-Kay JD*.

Cooperative interactions and a non-native buried Trp in the unfolded state of an SH3 domain.

J Mol Biol 2002 (322): 163-178.

doi: 10.1016/S0022-2836(02)00741-6

Tollinger M, Forman-Kay JD, Kay LE*.

Measurement of side-chain carboxyl pK(a) values of glutamate and aspartate residues in an unfolded protein by multinuclear NMR spectroscopy.

J Am Chem Soc 2002 (124): 5714-5717.

doi: 10.1021/ja020066p

Tollinger M, Skrynnikov NR, Mulder FA, Forman-Kay JD, Kay LE*.

Slow dynamics in folded and unfolded states of an SH3 domain.

J Am Chem Soc 2001 (123): 11341-11352.

doi: 10.1021/ja011300z

Choy WY, Tollinger M, Mueller GA, Kay LE*.

Direct structure refinement of high molecular weight proteins against residual dipolar couplings and carbonyl chemical shift changes upon alignment: an application to maltose binding protein.

J Biomol NMR 2001 (21): 31-40.

doi: 10.1023/A:1011933020122

Hoffmann B, Tollinger M, Konrat R, Huhta M, Marsh EN, Kräutler B*.

A protein pre-organized to trap the nucleotide moiety of coenzyme B12: refined solution structure of the B12-binding subunit of glutamate mutase from Clostridium tetanomorphum.

Chembiochem 2001 (2): 643-655.

doi: 10.1002/1439-7633(20010903)2:9<643::AID-CBIC643>3.0.CO;2-J

Eichmüller C, Tollinger M, Kräutler B, Konrat R*.

Mapping the ligand binding site at protein side-chains in protein-ligand complexes through NOE difference spectroscopy.

J Biomol NMR 2001 (20): 195-202.

doi: 10.1023/A:1011299009214

Tollinger M, Eichmüller C, Konrat R, Huhta MS, Marsh EN, Kräutler B*.

The B12-binding subunit of glutamate mutase from Clostridium tetanomorphum traps the nucleotide moiety of coenzyme B12.

J Mol Biol 2001 (309): 777-791.

doi: 10.1023/A:1011299009214

Konrat R*, Tollinger M.

Heteronuclear relaxation in time-dependent spin systems: 15N T1-rho dispersion during adiabatic fast passage.

J Biomol NMR 1999 (13): 213-221.

doi: 10.1023/A:1008324721356

Tollinger M, Konrat R, & Kräutler B*. 

The structure of methylcob(II)alamin in aqueous solution - a water molecule as structuring element of the nucleotide loop.

Helv Chim Acta 1999 (82): 1596-1609.

doi: 10.1002/(SICI)1522-2675(19991006)82:10<1596::AID-HLCA1596>3.0.CO;2-K

Kontaxis G, Riether D, Hannak R, Tollinger M, Kräutler, B*.

Electrochemical synthesis and structure analysis of neocoenzyme B12 - an epimer of coenzyme B12 with a remarkably flexible organometallic group.

Helv Chim Acta 1999 (82): 848-869.

doi: 10.1002/(SICI)1522-2675(19990609)82:6<848::AID-HLCA848>3.0.CO;2-L

Zieger G, Sterk H, Bermel W, Konrat R, Tollinger M, Kräutler B, Werbelow, L.* 

Relaxation-induced polarization transfer and determination of methyl group 13C chemical shielding anisotropy.

J Phys Chem A 1999 (103): 5253-5258.

doi: 10.1021/jp990409e

Tollinger M, Konrat R, Hilbert BH, Marsh EN, Kräutler B*.

How a protein prepares for B12 binding: structure and dynamics of the B12-binding subunit of glutamate mutase from Clostridium tetanomorphum.

Structure 1998 (6): 1021-1033.

doi: 10.1016/S0969-2126(98)00103-8


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