Books

Publications

59. Synthesis of Waixenicin A: Exploring Strategies for Nine-Membered Ring Formation​. C. Steinborn, T. Huber, J. Lichtenegger, I. Plangger, D. Höfler, S. D. Schnell, L. Weisheit, P. Mayer, K. Wurst, T. Magauer*, Chem. Eur. J, 2023, 10.1002/chem.202303489. (PDF-OA).

2023_cej_waixenicin_toc_revised


58. Divergent Polyene Cyclization for the Total Synthesis of Greenwayodendrines, Greenwaylactams, Polysin and Polyveoline, I. Plangger, T. Pinkert, K. Wurst, T. Magauer*,  Angew. Chem., Int. Ed. 2023, 62, e202307719. (PDF-OA)

2023_Greenwaylactam_Polyenenew


57. Total Syntheses of (+)-Waixenicin A, (+)-9-Deacetoxy-14,15-deepoxyxeniculin and (–)-Xeniafaraunol A, C. Steinborn, T. Huber, J. Lichtenegger, I. Plangger, K. Wurst, T. Magauer*,  J. Am. Chem. Soc. 2023, 145, 11811–11817. (PDF-OA)
2023_Waixcenicin


56. Investigations into Simplified Analogues of the Herbicidal Natural Product (+)-Cornexistin, C. Steinborn, A. Tancredi, C. Habiger, C. Diederich, J. Kramer, A. Reingruber, B. Laber, J. Freigang, G. Lange, D. Schmutzler, A. Machettira, G. Besong, T. Magauer*, David M. Barber*,  Chem. Eur. J. 2023, 29, e202300199. (PDF-OA)
2023_SAR_Cornexistin


55. Total Synthesis of the Dihydrooxepine-Spiroisoxazoline Natural Product Psammaplysin A, J. Paciorek, D. Hoefler, K. R. Sokol, K. Wurst, T. Magauer*,  J. Am. Chem. Soc. 2022, 144, 19704–19708. (PDF-OA)
ChemRxiv DOI: 10.26434/chemrxiv-2022-px26h.

2022_Psammplysin_JACS


54. Short, Divergent and Enantioselective Total Synthesis of Bioactive ent-Pimaranes. I. Plangger, K. Wurst, T. Magauer*, Org. Lett. 2022, 24, 7151−7156. (PDF-OA)

 OL_Pimaranes_2022


53. KS0365, a novel activator of the transient receptor potential vanilloid 3 (TRPV3) channel, accelerates keratinocyte migration. M. Maier, S. Olthoff, K. Hill, C. Zosel, T. Magauer, L. A. Wein, M. Schaefer, Br J Pharmacol. 2022179, 5290–5304. (PDF-OA)

2022_BJP_Schaefer2022


52. A General Entry to Ganoderma Meroterpenoids: Synthesis of Lingzhiol via Photoredox Catalysis. A. Rode, K. Wurst, T. Magauer*, ChemRxiv 2022, DOI: 10.26434/chemrxiv-2022-svqft. (PDF-OA)

2022_chemrxiv_ganoderma


51. Total Synthesis and Late-Stage C–H Oxidations of ent-Trachylobane Natural Products. L. A. Wein, K. Wurst, T. Magauer*, Angew. Chem., Int. Ed. 202261, e202113829 (VIP). (PDF-OA)

 2021_ACIE_revision_Lukas


50. Ring-Expansion of 1-Indanones to 2-Halo-1-naphthols as an Entry Point to Gilvocarcin Natural Products. I. Zamarija, B. Marsh, T. Magauer*, Org. Lett. 202123, 9221−9226(PDF-OA)

2021_OrgLett_RingexpansionGilvo


49. Bifunctional Polyene Cyclizations: Synthetic Studies on Pimarane Natural Products. J. M. Feilner, I. Plangger, T. Magauer*, Chem. Eur. J. 2021, 27, 12410–12421. (PDF-OA)

2021_cej_pimarendiolfull


48. Total Synthesis of Oxepin and Dihydrooxepin Containing Natural Products. K. R. Sokol, T. Magauer*, Synthesis 202153, 4187-4202. (PDF)

2021_synthesisoxepin


47. Synthesis of Pyrroles via Consecutive 6π-Electrocyclization/Ring-Contraction of Sulfilimines. F.-L. Haut, N. Feichtinger; I. Plangger, L. Wein, M. Müller, T.-N. Streit, K. Wurst,  M. Podewitz, T. Magauer*, J. Am. Chem. Soc. 2021143, 9002–9008. (PDF-OA)

2021_Pyrroles_JACS


46. Evolution of a Strategy for the Total Synthesis of (+)-Cornexistin. R. E. Wildermuth, C. Steinborn, D. M. Barber, K. S. Mühlfenzl, M. Kendlbacher, P. Mayer, K. Wurst, T. Magauer*, Chem. Eur. J. 2021, 27, 1218112189. (PDF-OA)

2021_CEJ_Cornexistin


45. The 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry. A. Ciulli, L. Hamann, W. Jahnke, A. Kalgutkar, T. Magauer, T. Ritter, V. Steadman, S. D. Williams, G. Winter, K. Hoegenauer, K. H. Krawinkler, A. F. Stepan, ChemMedChem 2021, 16, 2417–24232. (PDF-OA)


44. Beyond the Isoprene Pattern: Bifunctional Polyene Cyclizations. J. M. Feilner, F.-L. Haut, T. Magauer*, Chem. Eur. J. 202127, 7017–7021. (PDF-OA) (Concept Article)

2021_conceptPolyene


43. Rapid Assembly of Tetrasubstituted Furans via Pummerer-type Rearrangement. F.-L. Haut, C. Habiger, L. A. Wein, K. Wurst, M. Podewitz*, T. Magauer* J. Am. Chem. Soc. 2021, 143, 1216–1223. (PDF-OA)

2021_Furans_JACS


42. Synthesis of Vicinal Quaternary All-Carbon Centers via Acid-catalyzed Cycloisomerization of Neopentylic Epoxides.
M. Schmid, K. R. Sokol, L. A. Wein, S. Torres Venegas, C. Meisenbichler, K. Wurst, M. Podewitz,  T. Magauer*, Org. Lett. 2020, 22, 6526–6531. (PDF-OA).

2020_Org_lett_Tetralins



41. Total Synthesis of (+)-Cornexistin.
C. Steinborn, R. E. Wildermuth, D. M. Barber,  T. Magauer*, Angew. Chem., Int. Ed. 2020, 59, 17282–17285. (PDF-OA)

2020_cornexisitin_toc_


40. A Transannular Polyene Tetracyclization for the Rapid Construction of the Pimarane Framework.
J. M. Feilner, K. Wurst,  T. Magauer*, Angew. Chem., Int. Ed. 2020, 59, 12436–12439. (PDF-OA)

 2020_pimarane_toc_revised


39. Synthesis of (–)-Mitrephorone A via a Bio-inspired Late Stage C–H Oxidation of (–)-Mitrephorone B.
L. A. Wein, K. Wurst, P. Angyal, L. Weisheit, T. Magauer*, J. Am. Chem. Soc. 2019, 141, 19589–19593. (PDF-OA)

2020_Mitrephorone B and A


38. A Synthetic Entry to Polyfunctionalized Molecules through the [3+2]-Cycloaddition of Thiocarbonyl Ylides.
F.-L. Haut, C. Habiger, K. Speck, K. Wurst, P. Mayer, J. N. Korber, T. Müller, T. Magauer*, J. Am. Chem. Soc. 2019, 141, 13352−13357. (PDF-OA)

2019_JACS_High_pressure


37. Ring-Expansion Approaches for the Total Synthesis of Salimabromide.
M. Schmid, A. Grossmann, P. Mayer, T. Müller, T. Magauer*, Tetrahedron 2019, 75, 3195–3215. (PDF-OA)

2019_Tet_Salimabromide


36. Total Synthesis of Salimabromide, a Tetracyclic Polyketide from a Marine Myxobacterium.
M. Schmid, A. Grossmann, K. Wurst, T. Magauer*, J. Am. Chem. Soc. 2018, 140, 8444–8447. (PDF-OA)

This work was highlighted as Synfact of the Month: E. M. Carreira, N. Sievertsen, Synfacts 2018, 14, 0887. (PDF)

2018_JACS_salimabromide


35. A Negishi cross-coupling reaction enables the total synthesis of (+)-stachyflin.
F.-L. Haut, K. Speck, R. Wildermuth, K. Möller, P. Mayer, T. Magauer*, Tetrahedron 2018, 74, 3348–3357. (PDF)

 2018_tetrahedron_stachyflin_new


34. 9-Membered Carbocycles: Strategies and Tactics for their Synthesis.
T. Huber, R. Wildermuth, T. Magauer*, Chem. Eur. J. 2018, 24, 12107–12120. (PDF-OA)

 9-membered-rings


33. De Novo Synthesis of Benzannelated Heterocycles.
J. Feierfeil, T. Magauer*, Chem. Eur. J. 2018, 24, 1455–1458. (PDF)

Heterocycles_Johannes


32. A Modular Synthesis of Tetracyclic Meroterpenoid Antibiotics.
R. Wildermuth, K. Speck, F.-L. Haut, P. Mayer, B. Karge, M. Brönstrup, T. Magauer*, Nat. Commun. 2017, 8, 2083. (PDF-OA)

 2017_Nat_Commun_Meroterpenoids


31. Development of a β-C–H Bromination Approach Towards the Synthesis of Jerantinine E.
T. Huber, T. Unzner, C. Gerlinger, T. Magauer*J. Org. Chem. 2017, 82, 7410–7419. (PDF)

JOC_Tatjana_Tesi_Christa


30. Dyotropic Rearrangements in Natural Product Synthesis and Biosynthesis.
C. L. Hugelshofer, T. Magauer*Nat. Prod. Rep2017, 34, 228–234. (Highlight) (PDF)



29. Bioinspired Total Syntheses of Terpenoids.
C. L. Hugelshofer, T. Magauer*, Org. Biomol. Chem. 201715, 12–16. (Perspective) (PDF)



28. Evolution of a Polyene Cyclization Cascade for the Total Synthesis of (–)-Cyclosmenospongine.
K. Speck, T. Magauer*, Chem. Eur. J. 2017, 23, 1157–1165. (HOT PAPER) (PDF)



27. Convergent Assembly of the Tetracyclic Meroterpenoid (–)-Cyclosmenospongine via a Non-Biomimetic Polyene Cyclization.
K. Speck, R. Wildermuth, T. Magauer*, Angew. Chem. Int. Ed. 2016, 55, 14131–14135. (PDF)


This work was highlighted in SYNFACTS: E. M. Carreira, P. Sondermann, Synfacts 2017, 13, 5.


26. A Divergent Approach to the Marine Diterpenoids (+)-Dictyoxetane and (+)-Dolabellane V.
C. L. Hugelshofer, T. Magauer*Chem. Eur. J. 201622, 15125–15136. (PDF)



25. Rapid Access to Orthogonally Functionalized Naphthalenes: Application to the Total Synthesis of the Anticancer Agent Chartarin.
T. A. Unzner, A. Grossmann, T. Magauer*Angew. Chem., Int. Ed. 2016, 55, 9763–9767. (HOT PAPER) (PDF)



24. A Bioinspired Cyclization Sequence Enables the Asymmetric Total Synthesis of Dictyoxetane.
C. L. Hugelshofer, T. Magauer*J. Am. Chem. Soc. 2016, 138, 6420–6423. (PDF)

This work was highlighted in SYNFACTS: E. M. Carreira, H. Wolleb, Synfacts 201612, 771. 


23. Gold(I)-Catalyzed Enyne Cyclizations: Studies Towards the Total Synthesis of (+)-Aureol.
R. Wildermuth, K. Speck, T. Magauer*, Synthesis, 2016, 48, 1814–1824. (PDF)



22. Trihaloethenes as Versatile Building Blocks for Organic Synthesis.
A. Grossmann, T. Magauer*, Org. Biomol. Chem. 2016, 14, 5377–5389 (Review). (PDF)

 


21. Synthesis of Xenia diterpenoids and related metabolites isolated from marine organisms.
T. Huber, L. Weisheit, T. Magauer*, Beilstein J. Org. Chem. 201511, 2521–2539 (Review). (PDF)


20. Ring Opening of Bicyclic[3.1.0]hexan-2-ones: A Versatile Synthetic Platform for the Construction of Substituted Benzoates.
J. Feierfeil, A. Grossmann, T. Magauer*, Angew. Chem., Int. Ed. 2015, 54, 11835–11838. (PDF)



19. The 50th EUCHEM Conference on Stereochemistry (Bürgenstock Conference 2015).
A. Adibekian, T. Magauer*, Chimia, 201569, 485–487 (Conference Report). (PDF)


18. Sequential O–H/C–H Bond Insertion of Phenols initiated by the Gold(I)-Catalyzed Cyclization of 1-Bromo-1,5-Enynes.
K. Speck, K. Karaghiosoff, T. Magauer*, Org. Lett. 2015, 17, 1982–1985. (PDF)



17. Total Synthesis of the Leucosceptroid Family of Natural Products.
C. L. Hugelshofer, T. Magauer*, J. Am. Chem. Soc. 2015, 137, 3807–3810. (PDF)



16. Experimental Studies on the Selective beta-C-H Halogenation of Enones.
T. Huber, J. Rickmeier, D. Kaiser, T. Magauer*, J. Org. Chem. 2015, 80, 2281–2294. (PDF)



15. Chemical Synthesis of Antifeedant Leucosceptroids.
C. L. Hugelshofer, K. Speck, A. S. Grossmann, T. Magauer*, Beilstein TV, 2015. Beilstein Video


14. Carbon-Fluorine Bond Activation for the Synthesis of Functionalized Molecules.
T. A. Unzner, T. Magauer*Tetrahedron Lett. 2015, 56, 877–883 (Review). (PDF)


13. Strategies for the Synthesis of Antifeedant Leucosceptroid Natural Products.
C. L. Hugelshofer, T. Magauer*Synlett 2015, 26, 572–579 (Review)(PDF)



12. Unraveling the Metabolic Pathway in Leucosceptrum canum by Isolation of New Defensive Leucosceptroid Degradation Products and Biomimetic Model Synthesis.
S.-H. Luo, C. L. Hugelshofer, J. Hua, S.-X. Jing, C.-H. Li, Y. Liu, X.-N. Li, X. Zhao, T. Magauer*, S.-H. Li*, Org. Lett. 2014, 16, 6416–6419.  (PDF)

 


11. A General Entry to Antifeedant Sesterterpenoids: Total Synthesis of (+)-Norleucosceptroid A, (–)-Norleucosceptroid B, and (–)-Leucosceptroid K.
C. L. Hugelshofer, T. Magauer*Angew. Chem., Int. Ed. 2014, 53, 11351–11355.  (PDF)

This work was selected as SYNFACT of the month: E. M. Carreira, M. Westphal, Synfacts 201410, 1233.


10. Crystalline guanine adducts of natural and synthetic trioxacarcins suggest a common biological mechanism and reveal a basis for the instability of trioxacarcin.
K. Pröpper, B. Dittrich, D. J. Smaltz, T. Magauer, A. G. Myers, Biorg. Med. Chem. Lett. 2014, 24, 4410–4413.  (PDF)


9. A transition metal-free synthesis of fluorinated naphthols.
J. Hammann, T. Unzner, T. Magauer*, Chem. Eur. J. 2014, 20, 6733–6738.  (PDF)

This work was highlighted in SYNFACTS: P. Knochel, D. Haas, Synfacts 2014, 10, 853.



8. High-Pressure Transformations in Natural Product Synthesis.
C. L. Hugelshofer, T. Magauer*Synthesis 2014, 46, 1279–1296 (Review). (PDF)

 


7. The Chemistry of Isoindole Natural Products.
K. Speck, T. Magauer*Beilstein J. Org. Chem. 20139, 2048–2078 (Review). (PDF)



6. Component-Based Syntheses of Trioxacarcin A, DC-45-A1, and Structural Analogs.
T. Magauer, D. Smaltz, A. G. Myers, Nat. Chem. 20135, 886–893. (PDF)

 

5. Short and Efficient Synthetic Route to Methyl α-Trioxacarcinoside B and Anomerically Activated Derivatives.
T. Magauer, A. G. Myers, Org. Lett. 201113, 5584–5587. (PDF)

 

4. In Pursuit of a Competitive Target: the Total Synthesis of the Antibiotic Kendomycin.
H. J. Martin, T. Magauer, J. Mulzer, Angew. Chem., Int. Ed. 2010, 49, 5614–5626 (Review). (PDF)

 

3. Ring Closing Metathesis and Photo–Fries Reaction for the Construction of the Ansamycin Antibiotic Kendomycin. Development of a Protecting Group Free Oxidative Endgame.
T. Magauer, H. J. Martin, J. Mulzer, Chem. Eur. J. 2010, 16, 507–519. (PDF)

 

2. Total Synthesis of (+)–Echinopine A and B: Determination of Absolute Stereochemistry.
T. Magauer*, J. Mulzer, K. Tiefenbacher,* Org. Lett. 200911, 5306–5309. (PDF)

 

1. Total Synthesis of the Antibiotic Kendomycin by Macrocyclization via Photo–Fries Rearrangement and Ring Closing Metathesis.
T. Magauer, H. J. Martin, J. Mulzer, Angew. Chem., Int. Ed. 200948, 6032–6036. (PDF)

 

 

Patents

Trioxacarcins and Uses Thereof,  Andrew G. Myers, Nicholas E. Hill, Jakub Svenda, Robert T. Yu, Daniel J. Smaltz, and Thomas Magauer, International PCT Patent Application No. PCT/US2011/029343, filed March 22, 2011.

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