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Publications

 

All articles

Peer-reviewed publications can be found on  PubMed.

 

Selected articles

 

  1. Su, F., Koeberle, A. (2023) Regulation and targeting of SREBP-1 in hepatocellular carcinoma. Cancer Metastasis Rev, doi.org/10.1007/s10555-023-10156-5
  2. Koeberle SC, Kipp AP, Stuppner H, Koeberle A. (2022) Ferroptosis-modulating small molecules for targeting drug-resistant cancer: Challenges and opportunities in manipulating redox signaling. Med Res Rev. 2023 Jan 19. doi: 10.1002/med.21933. Epub ahead of print. PMID: 36658724.
  3. Thuermer, M., Gollowitzer, A., Pein, H., Neukirch, K., Gelmez, E., Waltl, L., Wielsch, N., Winkler, R., Loeser, K., Grander, J., Hotze, M., Harder, S., Döding, A., Meßner, M., Troisi, F., Ardelt, M., Schlüter, H., Pachmayr, J., Gutiérrez-Gutiérrez, O., Rudolph, L., Thedieck, K., Schulze-Späte, U., González-Estévez, C., Kosan, C., Svatoš, A., Kwiatkowski, M., Koeberle, A. (2022) PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling. Nat Commun, 13, 2982
  4. Neukirch, K., Alsabil, K., Dinh, C., Bilancia, R., Raasch, M., Ville, A., Cerqua, I., Viault, G., Bréard, D., Pace, S., Temml, V., Brunner, E., Jordan, P.M., Marques, M.C., Loeser, K., Gollowitzer, A., Permann, S., Gerstmeier, J., Lorkowski, S., Stuppner, H., Garscha, U., Rodrigues, T., Bernardes, G.J.L., Schuster, D., Séraphin, D., Richomme, P., Rossi, A., Mosig, A., Roviezzo, F., Werz, O., Helesbeux, JJ., Koeberle, A. (2021) Exploration of long-chain vitamin E metabolites for the discovery of a highly potent, orally effective and metabolically stable 5-LOX inhibitor that limits inflammation. J Med Chem
  5. Van Anh, T.T., Mostafa, A., Rao, Z., Pace, S., Schwaiger, S., Kretzer, C., Temml, V., Giesel, C., Jordan, P.M., Bilancia, R., Weinigel, C., Rummler, S., Waltenberger, B., Hung, T., Rossi, A., Stuppner, H., Werz, O., Koeberle, A. (2021) From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution. Acta Pharm Sin B, 11, 1629-1647
  6. Espada, L., Dakhovnik, A., Chaudhari, P., Martirosyan, A., Miek, L., Poliezhaieva, T., Schaub, Y., Nair, A., Doring, N., Rahnis, N., Werz, O., Koeberle, A., Kirkpatrick, J., Ori, A., Ermolaeva, M. A. (2020) Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegans. Nat Metab, 2, 1316-1331

  7. Pein, H., Ville, A., Pace, S., Temml, V., Garscha, U., Raasch, M., Alsabil, K., Viault, G., Dinh, C., Guilet, D., Troisi, F., Neukirch, K., König, S., Waltenberger, B., Stuppner, H., Wallert, M., Lorkowski, S., Weinigel, C., Rummler, S., Birringer, M., Sautebin, L., Helesbeux, JJ., Séraphin, D., Mosig, A., Schuster, D., Rossi, A., Richomme, P., Werz, O., Koeberle, A. (2018) Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase. Nat Commun, 9, 3834

  8. Reker, D., Perna, A.M., Reutlinger, M., Schneider, P., Rodrigues, T., Mönch, B., Koeberle, A., Lamers, C., Gabler, M., Steinmetz, H., Müller, R., Schubert-Zsilavecz, M., Werz, O., Schneider, G. (2014) Revealing the macromolecular targets of complex natural products. Nat Chem, 6, 1072-1078

  9. Koeberle, A., Shindou, H., Koeberle S.C., Laufer S.A., Shimizu, T., Werz, O. (2013) Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding, Proc Natl Acad Sci U S A, 110, 2546-2551

  10. Koeberle, S.C., Romir, J., Fischer, S., Koeberle, A., Schattel, V., Albrecht, W., Grütter, C., Werz, O., Rauh, D., Stehle, T., Laufer, S. (2011) Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor. Nat Chem Biol, 25, 141-143
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