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All articles

Peer-reviewed publications can be found on  PubMed.


Selected articles

  1. Pein, H., Ville, A., Pace, S., Temml, V., Garscha, U., Raasch, M., Alsabil, K., Viault, G., Dinh, C., Guilet, D., Troisi, F., Neukirch, K., König, S., Waltenberger, B., Stuppner, H., Wallert, M., Lorkowski, S., Weinigel, C., Rummler, S., Birringer, M., Sautebin, L., Helesbeux, JJ., Séraphin, D., Mosig, A., Schuster, D., Rossi, A., Richomme, P., Werz, O., Koeberle, A. (2018) Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase. Nat Commun, 9, 3834
  2. Pein, H., Koeberle, S.C., Voelkel, M., Schneider, F., Rossi, A., Thürmer, M., Loeser, K., Sautebin, L., Morrison, H., Werz, O., Koeberle, A. (2017) Vitamin A regulates Akt signaling through the phospholipid fatty acid composition. FASEB J, 31, 4566-4577
  3. Pace, S., Pergola, C., Dehm, F., Rossi, A. Gerstmeier, J., Troisi, F., Pein, H., Schaible, A.M., Weinigel, C., Rummler, S., Northoff, H., Laufer, S., Maier, T.J., Rådmark, O., Samuelsson, B., Koeberle, A., Sautebin, L., Werz, O. (2017) Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males. J Clin Invest, 127, 3167-3176
  4. Koeberle, A., Pergola, C., Shindou, H., Koeberle, S.C., Shimizu, T., Laufer, S.A., Werz, O. (2015) Role of p38 mitogen-activated protein kinase in linking stearoyl-CoA desaturase-1 activity with ER homeostasis. FASEB J., 29, 2439-2449
  5. Koeberle, A., Eduardo, M., Appendino, G., Minassi, A., Weinigel, C., Barz, D., Caprioglio, D., Collado, J.A., Werz, O. (2014) SAR studies on curcumin’s pro-inflammatory targets: discovery of prenylated pyrazolocurcuminoids as potent and selective novel inhibitors of 5-lipoxygenase. J Med Chem, 57, 5638- 5648
  6. Reker, D., Perna, A.M., Reutlinger, M., Schneider, P., Rodrigues, T., Mönch, B., Koeberle, A., Lamers, C., Gabler, M., Steinmetz, H., Müller, R., Schubert-Zsilavecz, M., Werz, O., Schneider, G. (2014) Revealing the macromolecular targets of complex natural products. Nat Chem, 6, 1072-1078
  7. Koeberle, A., Shindou, H., Koeberle S.C., Laufer S.A., Shimizu, T., Werz, O. (2013) Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding, Proc Natl Acad Sci U S A, 110, 2546-2551
  8. Koeberle, S.C., Romir, J., Fischer, S., Koeberle, A., Schattel, V., Albrecht, W., Grütter, C., Werz, O., Rauh, D., Stehle, T., Laufer, S. (2011) Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor. Nat Chem Biol, 25, 141-143
  9. Koeberle, A., Zettl, H., Greiner, C., Wurglics, M., Schubert-Zsilavecz, M., Werz, O. (2008) Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. J Med Chem, 51, 8068-8076
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