Andreas Bernkop-Schnürch

Univ.-Prof. Mag. pharm. Dr. rer. nat.

Head

E-Mail: Andreas.Bernkop@uibk.ac.at
Phone:
+43 512 507-58600
Fax: +43 512 507-58699


Bernkop 

Personal Details:

Name: Univ.-Prof. Dr. Andreas BERNKOP SCHNÜRCH
Born: 1965, Klagenfurt
Nationality: Austrian
Marital status: Married; 3 children;

 

Academic education and positions held:

 

March 2013 - Feb. 2017
Head of the Institute of Pharmacy
May 2006 – Feb. 2013 Dean of the Faculty of Chemistry and Pharmacy
Since September 2003 Chairman of the Department of Pharmaceutical Technology, Leopold-Franzens-Universität, Innsbruck
April 2001 Offer for the C3-Professur, Institute of Pharmaceutical Technology and Biopharmaceutics, Ludwig-Maximilians-University, Munich, Germany
June 2000 Offer for the Chair in Pharmaceutics, School of Pharmacy, University of London
March 1999 Associate Professor at the Institute of Pharmaceutical Technology and Biopharmaceutics, University of Vienna
Nov. 1998 Habilitation for Pharmaceutical Technology, University of Vienna
April 1998 Second position in the ranking for the Chair in Pharmaceutical Technology and Biopharmaceutics (C4-Professor), Ludwig-Maximilians-University, Munich, Germany
May 1996 Proof of qualification for the wholesale trade of drugs
1994 Reader for: ‘Peptide and Protein Drugs’ ‘Manufacturing of Cosmetics’ and ‘Manufacturing of Dosage Forms’
Oct. 1993 - May 1994 Military service
April 1994 Graduation as doctor for natural sciences at the University of Vienna
June 1991 - Oct. 1992 Scientific work at the Institute of Microbiology and Genetics, University of Vienna
March 1991 Employment as ‘University Assistant’ at the Institute of Pharmaceutical Technology, University of Vienna
1990-1991 Practicing at a pharmacy in Vienna
Feb. 1990 Master degree at the University of Vienna
1984-1990 Study of pharmacy at the University of Vienna
1976-1984 Secondary school (Bundesgymnasium, St. Veit/Glan) -stress on natural science
1972-1976 Public primary school in St. Veit/Glan

 

Prizes awarded:

 

1997 HERBA-Award
1999 Research-Award of the City of Vienna
2000 Eurand-Award
2001 Best of Biotech Award
2002 MBPW Award
2003 Best of Biotech Award
2004 Adventure X Award
2005 Phoenix Award
2006 Houska-Award
2008 Austrian Innovation Award
2008 Austrian Nano Award
2015 Ernst Brandl Award

Research Funding:

 

FWF projects

1998-2001 Development of drug delivery systems for the peroral administration of peptide and protein drugs
1999-2002 Development of drug carrier systems with improved mucoadhesive properties
2000-2002 Ocularia based on new mucoadhesive polymers
2002-2005 Thiolated polymers in peptide drug delivery systems
2003-2005 Synthesis and evaluation of thiolized chitosan derivatives
2004-2006 Development of novel non absorbable permeation enhancers
2005- 2007 Design and characterisation of thiomer-nanoparticles
2011-2016 Preactivated thiomers
 
BFS project
 
2007-2008 Kationische Nanopartikel zum Targeting der Angiogenese
 
FFG project
 
2005-2012 Nano-structured materials for drug targeting, release and imaging (Nano-Health)
 
EU projects
2006-2010 Nanoscale functionalities for targeted drug delivery of biopharmaceutics (NANOBIOPHARMACEUTICS)

2012-2016

Mucus Permeating Nanoparticulate Drug Delivery Systems
(ALEXANDER)
 

Editorial/Advisory Board Member:

 

  • Biomedical Research International
  • Drug Delivery Letters
  • Drug Development Industrial Pharmacy
  • European Journal of Pharmaceutics and Biopharmaceutics
  • Journal of Drug Delivery
  • Journal of Drug Delivery Science and Technology
  • Journal of Drug Discovery, Development and Delivery
  • Pharmaceutical Research
  • Scientia Pharmaceutica
  • World Journal of Pharmacology
  • World Journal of Translational Medicine

Theme Editor for:

 

  • Advanced Drug Delivery Reviews
  • Journal of Drug Targeting
  • European Journal of Pharmaceutics and Biopharmaceutics

Publications:

 

Research Articles:

  1.  Albrecht-Schgoer, K.; Barthelmes, J.; Schgoer, W.; Theurl, M.; Nardin, I.; Lener, D.; Gutmann, C.; Dünnhaupt, S.; Bernkop-Schnürch, A.; Kirchmair, R.; (2017). Nanoparticular delivery system for a secretoneurin derivative induces angiogenesis in a hind limb ischemia model. J. Control. Rel., 250, 1-8.
  2. Efiana, N.A.; Mahmood, A.; Lam, H.T.; Zupančič, O.; Leonaviciute, G.; Bernkop-Schnürch, A. (2017). Improved mucoadhesive properties of self-nanoemulsifying drug delivery systems (SNEDDS) by introducing acyl chitosan. Int. J. Pharm., 519, 206-212.
  3. Fabiano, A.; Zambito, Z.; Bernkop-Schnürch, A. (2017). About the impact of water movement on the permeation behaviour of nanoparticles in mucus. Int. J. Pharm., 517, 279-285.
  4. Griesser, J.; Hetényi, G.; Moser, M.; Demarne, F.; Jannin, V.; Bernkop-Schnürch, A. (2017). Hydrophobic ion pairing: Key to highly payloaded self-emulsifying peptide drug delivery systems. Int. J. Pharm., 520, 267-274.
  5. Grießinger, J.A.; Bonengel, S.; Partenhauser, A.; Ijaz, M.; Bernkop-Schnürch, A. (2017). Thiolated polymers: evaluation of their potential as dermoadhesive excipients. Drug Dev. Ind. Pharm., 43(2), 204-212.
  6. Hetényi, G.; Griesser, J.; Moser, M.; Demarne, F.; Jannin, V.; Bernkop-Schnürch, A. (2017). Comparison of the protective effect of self-emulsifying peptide drug delivery systems towards intestinal proteases and glutathione. Int. J. Pharm., 523, 357-365.
  7. Hetényi, G.; Griesser, J.; Nardin, I.; Bernkop-Schnürch, A. (2017). Combination of SEDDS and Preactivated Thiomer Technology: Incorporation of a Preactivated Thiolated Amphiphilic Polymer into Self-Emulsifying Delivery Systems. Pharm. Res., 34(6), 1171-1179.
  8. Köllner, S.; Nardin, I.; Markt, R.; Griesser, J.; Prüfert, F.; Bernkop-Schnürch, A. (2017). Self-emulsifying drug delivery systems: Design of a novel vaginal delivery system for curcumin. Eur. J. Pharm. Biopharm., 115, 268-275.
  9. Laffleur, F.; Knapp, K.; Suchaoin, W.; Partenhauser, A.; Netsomboon, K.; Bernkop-Schnürch, A. (2017). Comparison of mucoadhesive and cohesive features of poly(acrylic acid)-conjugates respective their molecular mass. Eur. J. Pharm. Biopharm., 113, 149-156.
  10. Laffleur, F.; Pschick, S.; Barthelmes, J.; Hauptstein, S.; Bernkop-Schnürch, A. (2017). Impact of surfactants on skin penetration of Dexpanthenol. Curr. Drug Deliv. [Epub ahead of print]
  11. Leonaviciute, G.; Adamovic, N.T.; Lam, H.T.; Rohrer, J.; Partenhauser, A.; Bernkop-Schnürch, A. (2017). Self-emulsifying drug delivery systems (SEDDS): Proof-of-concept how to make them mucoadhesive. Eur. J. Pharm. Biopharm., 112, 51-57.
  12. Lupo, N.; Fidahic, U.; Hetényi, G.; Griesser, J.; Bernkop-Schnürch, A. (2017). Inhibitory effect of emulsifiers in sedds on protease activity: Just an illusion? Int. J. Pharm., 526, 23-30.
  13. Mahmood, A.; Lanthaler, M.; Laffleur, F.; Huck, C.W.; Bernkop-Schnürch, A. (2017). Thiolated chitosan micelles: Highly mucoadhesive drug carriers. Carbohydr Polym., 167, 250-258.
  14. Menzel, C.; Jelkmann, M.; Laffleur, F.; Bernkop-Schnürch, A. (2017). Nasal drug delivery: Design of a novel mucoadhesive and in situ gelling polymer. Int. J. Pharm., 517, 196-202.
  15. Netsomboon, K.; Suchaoin, W.; Laffleur, F.; Prüfert, F.; Bernkop-Schnürch, A. (2017). Multifunctional adhesive polymers: Preactivated thiolated chitosan-EDTA conjugates. Eur. J. Pharm. Biopharm., 111, 26-32.
  16. Partenhauser, A.; Netsomboon, K.; Pereira de Sousa, I.; Laffleur, F.; Bernkop-Schnürch, A. (2017). Preactivated silicone oil as potential long-term vitreous replacement with nonemulsifying properties. J. Biomed. Mater. Res. B Appl. Biomater., 105(3), 551-559.
  17. Perrone, M.; Lopedota, A.; Liberati,E.; Russo, V.; Cutrignelli, A.; Laquintana, V.; de Sousa, I.P.; Franco, M.; Tongiani, S.; Denora, N.; Bernkop-Schnürch, A. (2017). Natural dendrimers: Synthesis and in vitro characterization of glycogen-cysteamine conjugates. Eur. J. Pharm. Biopharm., 115, 168-176.
  18. Prüfert, F.; Bonengel, S.; Menzel, C.; Bernkop-Schnürch, A. (2017). Enhancing the efficiency of thiomers: Utilizing a highly mucoadhesive polymer as backbone for thiolation and preactivation. Eur. J. Pharm. Sci., 96, 309-315.
  19. Rohrer, J.; Partenhauser, A.; Zupančič, O.; Leonavičiūtė, G.; Podričnik, S.; Bernkop-Schnürch, A. (2017). Thiolated gelatin films: Renaissance of gelatin as sustained intraoral dosage form. European Polymer Journal, 87, 48-59.
  20. Suchaoin, W.; Mahmood, A.; Netsomboon, K.; Bernkop-Schnürch, A. (2017). Zeta-potential-changing nanoparticles conjugated with cell-penetrating peptides for enhanced transfection efficiency. Nanomedicine (Lond). [Epub ahead of print]
  21. Suchaoin, W.; Pereira de Sousa, I.; Netsomboon, K.; Lam, H.T.; Laffleur, F.; Bernkop-Schnürch, A. (2017). Development and in vitro evaluation of zeta potential changing self-emulsifying drug delivery systems for enhanced mucus permeation. Int. J. Pharm., 510, 255-262.
  22. Suchaoin. W.; Bernkop-Schnürch, A. (2017). Nanocarriers protecting toward an intestinal pre-uptake metabolism. Nanomedicine (Lond). 12(3), 255-269.
  23. Zupančič, O.; Grießinger, J.A.; Lam, H.T.; Bernkop-Schnürch, A. (2017). Storage Stability of Bivalirudin: Hydrophilic Versus Lipophilic Solutions. J.Pharm. Sci. 106(5), 1322-1330.
  24. Bonengel, S.; Jelkmann, M.; Oh, S.; Mahmood, A.; Ijaz, M.; Bernkop-Schnürch, A. (2016). Charge changing phosphorylated polymers: Proof of in situ mucoadhesive properties. Eur. J. Pharm. Biopharm., 105, 203-208.
  25. Bonengel, S.; Prüfert, F.; Jelkmann, M.; Bernkop-Schnürch, A. (2016). Zeta potential changing phosphorylated nanocomplexes for pDNA delivery. Int. J. Pharm., 504, 117-124.
  26. Deutel, B.; Laffleur, F.; Palmberger, T.; Saxer, A.; Thaler, M.; Bernkop-Schnürch, A. (2016). In vitro characterization of insulin containing thiomeric microparticles as nasal drug delivery system. Eur. J. Pharm. Sci., 81, 157-161.
  27. Deutel, B.; Laffleur, F.; Thaurer, M.; Thaler, M.; Bernkop-Schnürch, A. (2016). Assembly and in vitro characterization of thiomeric nanoparticles. Drug Dev. Ind. Pharm., 42, 730-736.
  28. Grieβinger, J.A.; Hauptstein, S.; Laffleur, F.; Netsomboon, K.; Bernkop-Schnürch, A. (2016). Evaluation of the impact of multivalent metal ions on the permeation behavior of Dolutegravir sodium. Drug Dev. Ind. Pharm., 42, 1118-1126.
  29. Ijaz, M.; Ahmad, M.; Akhtar, N.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Thiolated α-Cyclodextrin: The Invisible Choice to Prolong Ocular Drug Residence Time. J. Pharm. Sci., 105, 2848-2854.
  30. Ijaz, M.; Bonengel, S.; Zupančič, O.; Yaqoob, M.; Hartl, M.; Hussain, S.; Huck, C.W.; Bernkop-Schnürch, A. (2016). Development of oral self nano-emulsifying delivery system(s) of lanreotide with improved stability against presystemic thiol-disulfide exchange reactions. Expert Opin. Drug Deliv., 13, 923-929.
  31. Ijaz, M.; Griessinger, J.A.; Mahmood, A.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Thiolated Cyclodextrin: Development of a Mucoadhesive Vaginal Delivery System for Acyclovir. J. Pharm. Sci., 105, 1714-1720.
  32. Leonaviciute, G.; Bonengel, S.; Mahmood, A.; Ahmad Idrees, M.; Bernkop-Schnürch, A. (2016). S-protected thiolated hydroxyethyl cellulose (HEC): Novel mucoadhesive excipient with improved stability. Carbohydr. Polym., 144, 514-521.
  33. Leonaviciute, G.; Suchaoin, W.; Matuszczak, B.; Lam, HT.; Mahmood, A.; Bernkop-Schnürch, A. (2016). Preactivated thiolated pullulan as a versatile excipient for mucosal drug targeting. Carbohydr. Polym., 151, 743-751.
  34. Leonaviciute, G.; Zupančič, O.; Prüfert, F.; Rohrer, J.; Bernkop-Schnürch, A. (2016). Impact of lipases on the protective effect of SEDDS for incorporated peptide drugs towards intestinal peptidases. Int. J. Pharm., 508, 102-108.
  35. Mahmood, A.; Bonengel, S.; Laffleur, F.; Ijaz, M.; Idrees, M.A.; Hussain, S.; Huck, C.W.; Matuszczak, B.; Bernkop-Schnürch, A. (2016). Can thiolation render a low molecular weight polymer of just 20-kDa mucoadhesive? Drug Dev. Ind. Pharm., 42, 686-693.
  36. Mahmood, A.; Prüfert, F.; Efiana, N.A.; Ashraf, M.I.; Hermann, M.; Hussain, S.; Bernkop-Schnürch, A. (2016). Cell-penetrating self-nanoemulsifying drug delivery systems (SNEDDS) for oral gene delivery. Expert Opin. Drug Deliv., 13, 1503-1512.
  37. Menzel, C.; Bonengel, S.; de Sousa, I.; Laffleur, F.; Prüfert, F.; Bernkop-Schnürch, A. (2016). Preactivated Thiolated Nanoparticles: A Novel Mucoadhesive Dosage Form. Int. J. Pharm., 497, 123-128.
  38. 39. Menzel, C.; Silbernagl, J.; Laffleur, F.; Leichner, C.; Jelkmann, M.; Huck, C.W.; Hussain, S.; Bernkop-Schnürch, A. (2016). 2,2'Dithiodinicotinyl ligands: Key to more reactive thiomers. Int. J. Pharm., 503, 199-206.
  39. Netsomboon, K.; Feßler, A.; Erletz, L.; Prüfert, F.; Ruetz, M.; Kieninger, C.; Kräutler, B.; Bernkop-Schnürch, A. (2016). Vitamin B12 and derivatives-In vitro permeation studies across Caco-2 cell monolayers and freshly excised rat intestinal mucosa. Int. J. Pharm., 497, 129-135.
  40. Netsomboon, K.; Laffleur, F.; Bernkop-Schnürch, A. (2016). P-glycoprotein inhibitors: synthesis and in vitro evaluation of a preactivated thiomer. Drug Dev. Ind. Pharm., 42, 668-675.0
  41. Netsomboon, K.; Laffleur, F.; Suchaoin, W.; Bernkop-Schnürch, A. (2016). Novel in vitro transport method for screening the reversibility of P-glycoprotein inhibitors. Eur. J. Pharm. Biopharm., 100, 9-14.
  42. Netsomboon, K.; Partenhauser, A.; Rohrer, J.; Sündermann, N.; Prüfert, F.; Suchaoin, W.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Preactivated thiomers for intranasal delivery of apomorphine: in vitro and in vivo evaluation. Eur. J. Pharm. Biopharm., 109, 35-42.
  43. Partenhauser, A.; Netsomboon, K.; Leonaviciute, G.; Bernkop-Schnürch, A. (2016). Evaluation of thiolated silicone oil as advanced mucoadhesive antifoaming agent. Drug Deliv., 23, 2711-2719.
  44. Partenhauser, A.; Zupancic, O.; Podricnik, S.; Rohrer, J.; Leichner, C.; Bernkop-Schnürch, A. (2016). Entirely S-protected silicone oil as second generation mucoadhesive agent. European Polymer Journal 76, 53-62.
  45. Partenhauser, A.; Zupančič, O.; Rohrer, J.; Bonengel, S.; Bernkop-Schnürch, A. (2016). Thiolated silicone oils as adhesive skin protectants for improved barrier function. Int. J. Cosmet.Sci. 38(3), 257-265
  46. Pereira de Sousa, I.; Buttenhauser, K.; Suchaoin, W.; Partenhauser, A.; Perrone, M.; Matuszczak, B.; Bernkop-Schnürch, A. (2016). Thiolated graphene oxide as promising mucoadhesive carrier for hydrophobic drugs. Int. J. Pharm., 509, 360-367.
  47. Pereira de Sousa, I.; Moser, T.; Steiner, C.; Fichtl, B.; Bernkop-Schnürch, A. (2016). Insulin loaded mucus permeating nanoparticles: Addressing the surface characteristics as feature to improve mucus permeation. Int. J. Pharm., 500, 236-244.
  48. Pereira de Sousa, I.; Suchaoin, W.; Zupančič, O.; Leichner, C.; Bernkop-Schnürch, A. (2016). Totally S-protected hyaluronic acid: Evaluation of stability and mucoadhesive properties as liquid dosage form. Carbohydr. Polym., 152, 632-638.
  49. Rohrer, J.; Partenhauser, A.; Hauptstein, S.; Gallati, C.; Matuszczak, B.; Abdulkarim, M.; Gunbleton, M.; Bernkop-Schnürch, A. (2016). Mucus permeating thiolated self-emusifying drug derlivery systems. Eur. J. Pharm. Biopharm., 98, 90-97.
  50. Sakloetsakun, D.; Preechagoon, D.; Bernkop-Schnürch, A.; Pongjanyakul, T. (2016). Chitosan-gum arabic polyelectrolyte complex films: physicochemical, mechanical and mucoadhesive properties. Pharm. Dev. Technol., 21, 590-599.
  51. Suchaoin, W.; Bonengel, S.; Grießinger, J.A.; Pereira de Sousa, I.; Hussain, S.; Huck, C.W.; Bernkop-Schnürch, A. (2016). Novel bioadhesive polymers as intra-articular agents: Chondroitin sulfate-cysteine conjugates. Eur. J. Pharm. Biopharm., 101, 25-32.
  52. Suchaoin, W.; Pereira de Sousa, I.; Netsomboon, K.; Lam, H.T.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Development and in vitro evaluation of zeta potential changing self-emulsifying drug delivery systems for enhanced mucus permeation. Int. J. Pharm., 510, 255-262.
  53. Suchaoin, W.; Pereira de Sousa, I.; Netsomboon, K.; Rohrer, J.; Hoffmann Abad, P.; Laffleur, F.; Matuszczak, B.; Bernkop-Schnürch, A. (2016). Mucoadhesive polymers: Synthesis and in vitro characterization of thiolated poly(vinyl alcohol). Int. J. Pharm., 503, 141-149.
  54. Zupančič, O.; Grießinger, J.A.; Rohrer, J.; Pereira de Sousa, I.; Danninger, L.; Partenhauser, A.; Sündermann, N.E.; Laffleur, F.; Bernkop-Schnürch, A. (2016). Development, in vitro and in vivo evaluation of a self-emulsifying drug delivery system (SEDDS) for oral enoxaparin administration. Eur. J. Pharm. Biopharm., 109, 113-121.
  55. Zupančič, O.; Leonaviciute, G.; Lam, H.T.; Partenhauser, A.; Podričnik, S.; Bernkop-Schnürch, A. (2016). Development and in vitro evaluation of an oral SEDDS for desmopressin. Drug Deliv., 23, 2074-2083.
  56. Zupančič, O.; Partenhauser, A.; Lam, H.T.; Rohrer, J.; Bernkop-Schnürch, A. (2016). Development and in vitro characterisation of an oral self-emulsifying delivery system for daptomycin. Eur. J. Pharm. Sci., 81, 129-136.
  57. Abdulkarim, M.; Agulló, N.; Cattoz, B.; Griffiths, P.; Bernkop-Schnürch, A.; Borros, S.G.; Gumbleton, M. (2015). Nanoparticle diffusion within intestinal mucus: Three-dimensional response analysis dissecting the impact of particle surface charge, size and heterogen
  58. Ay Şenyiğit, Z.; Karavana, S.Y.; İlem-Özdemir, D.; Çalışkan, Ç.; Waldner, C.; Şen, S.; Bernkop-Schnürch, A.; Baloğlu, E. (2015). Design and evaluation of an intravesical delivery system for superficial bladder cancer: preparation of gemcitabine HCl-loaded chitosan–thioglycolic acid nanoparticles and comparison of chitosan/poloxamer gels as carriers Int. J. Nanomedicine, 10, 6493-6507.
  59. Bonengel, S.; Hauptstein, S.; Leonaviciute, G.; Griessinger, J.; Bernkop-Schnürch, A. (2015). Thiolated alkyl-modified carbomers: Novel excipients for mucoadhesive emulsions. Eur. J. Pharm. Sci., 75, 123-130.
  60. Bonengel, S.; Prüfert, F.; Perera, G.; Schauer, J.; Bernkop-Schnürch, A. (2015). Polyethylene imine-6-phosphogluconic acid nanoparticles--a novel zeta potential changing system. Int. J. Pharm., 483, 19-25.
  61. Dünnhaupt, S.; Barthelmes, J.; Köllner, S.; Sakloetsakun, D.; Shahnaz, G.; Düregger, A.; Bernkop-Schnürch, A. (2015). Thiolated nanocarriers for oral delivery of hydrophilic macromolecular drugs. Carbohydr. Polym., 117, 577-584.
  62. Grabovac, V.; Laffleur, F.; Bernkop-Schnürch, A. (2015). Thiomers: Influence of molecular mass and thiol group content of poly(acrylic acid) on efflux pump inhibition. Int. J. Pharm., 493, 374-379.
  63. Hauptstein, S.; Dezorzi, S.; Prüfert, F.; Matuszczak, B.; Bernkop-Schnürch, A. (2015). Synthesis and in vitro characterization of a novel S-protected thiolated alginate. Carbohydr. Polym., 124, 1-7.
  64. Hauptstein, S.; Prüfert, F.; Bernkop-Schnürch, A. (2015). Self-nanoemulsifying drug delivery systems as novel approach for pDNA drug delivery. Int. J. Pharm., 487, 25-31.
  65. Hebar, A.; Koller, C.; Seifert, J.M.; Chabicovsky, M.; Bodenteich, A.; Bernkop-Schnürch, A.; Grassauer, A.; Prieschl-Grassauer, E. (2015). Non-clinical safety evaluation of intranasal iota-carrageenan. PLoS One. 10, e0122911.
  66. Ijaz, M.; Matuszczak, B.; Rahmat, D.; Mahmood, A.; Bonengel, S.; Hussain, S.; Huck, C.W.; Bernkop-Schnürch, A. (2015). Synthesis and characterization of thiolated β-cyclodextrin as a novel mucoadhesive excipient for intra-oral drug delivery. Carbohydr. Polym., 132, 187-195.
  67. Köllner, S.; Dünnhaupt, S.; Waldner, C.; Hauptstein, S.; Pereira de Sousa, I.; Bernkop-Schnürch, A. (2015). Mucus permeating thiomer nanoparticles. Eur. J. Pharm. Biopharm., 97(Pt A), 265-272.
  68. Laffleur, F.; Fischer, A.; Schmutzler, M.; Hintzen, F.; Bernkop-Schnürch, A. (2015). Evaluation of functional characteristics of preactivated thiolated chitosan as potential therapeutic agent for dry mouth syndrome. Acta Biomater., 21, 123-131.
  69. Laffleur, F.; Psenner, J.; Suchaoin, W. (2015). Permeation enhancement via thiolation: in vitro and ex vivo evaluation of hyaluronic acid-cysteine ethyl ester. J. Pharm. Sci., 104, 2153-2160.
  70. Leonaviciute, G.; Bernkop-Schnürch, A. (2015). Self-emulsifying drug delivery systems in oral (poly)peptide drug delivery. Expert Opin. Drug Deliv., 12, 1703-1716.
  71. Mahjub, R.; Dorkoosh, F.A.; Rafiee-Tehrani, M.; Bernkop-Schnürch, A. (2015). Oral self-nanoemulsifying peptide drug delivery systems: impact of lipase on drug release. J. Microencap., 32, 401-407.
  72. Mahmood, A.; Bonengel, S.; Laffleur, F.; Ijaz, M.; Leonaviciute, G.; Bernkop-Schnürch, A. (2015). An in-vitro exploration of permeation enhancement by novel polysulfonate thiomers. Int. J. Pharm., 496, 304-313.
  73. Palmberger, T.F.; Laffleur, F.; Greindl, M.; Bernkop-Schnürch, A. (2015). In vivo evaluation of anionic thiolated polymers as oral delivery systems for efflux pump inhibition. Int. J. Pharm., 491, 318-322.
  74. Partenhauser, A.; Laffleur, F.; Rohrer, J.; Bernkop-Schnürch, A. (2015). Thiolated silicone oil: synthesis, gelling and mucoadhesive properties. Acta Biomater., 16, 169-177.
  75. Pereira de Sousa, I.; Cattoz, B.; Wilcox, M.D.; Griffiths, P.C.; Dalgliesh, R.; Rogers, S.; Bernkop-Schnürch, A. (2015). Nanoparticles decorated with proteolytic enzymes, a promising strategy to overcome the mucus barrier. Eur. J. Pharm. Biopharm., 97(Pt A), 257-264.
  76. Pereira de Sousa, I.; Steiner, C.; Schmutzler, M.; Wilcox, M.D.; Veldhuis, J.; Pearson, J.P.; Huck, C.W.; Salvenmoser, W.; Bernkop-Schnürch, A. (2015). Mucus permeating carriers: formulation and characterization of highly densely charged nanoparticles. Eur. J. Pharm. Biopharm., 97(Pt A), 273-279.
  77. Perera, G.; Zipser, M.; Bonengel, S.; Salvenmoser, W.; Bernkop-Schnürch, A. (2015). Development of phosphorylated nanoparticles as zeta potential inverting systems. Eur. J. Pharm. Biopharm., 97(Pt A), 250-256.
  78. Rohrer, J.; Zupancic, O.; Suchaoin, W.; Netsoomboon, K.; Laffleur, F.; Oh, S.; Bernkop-Schnürch, A. (2015). Synthesis and in vitro characterization of preactivated thiolated gelatin. European Polymer Journal 73, 268–277.
  79. Suchaoin, W.; Bonengel, S.; Hussain, S.; Huck, C.W.; Ma, B.N.; Bernkop-Schnürch, A. (2015). Synthesis and In Vitro Evaluation of Thiolated Carrageenan. J. Pharm. Sci., 104, 2523-2530.
  80. Bonengel, S.; Bernkop-Schnürch, A. (2014). Thiomers - From bench to market. J. Control. Rel., 195, 120-129.
  81. Bonengel, S.; Hauptstein, S.; Perera, G.; Bernkop-Schnürch, A. (2014). Thiolated and S-protected hydrophobically modified cross-linked poly(acrylic acid) - A new generation of multifunctional polymers. Eur. J. Pharm. Biopharm., 88, 390-396.
  82. Hauptstein, S.; Bonengel, S.; Griessinger, J.; Bernkop-Schnürch, A. (2014). Synthesis and characterization of pH tolerant and mucoadhesive (thiol-polyethylene glycol) chitosan graft polymer for drug delivery. J. Pharm. Sci., 103, 594-601.
  83. Hauptstein, S.; Bonengel, S.; Rohrer, J.; Bernkop-Schnürch, A. (2014). Preactivated thiolated poly(methacrylic acid-co-ethyl acrylate): Synthesis and evaluation of mucoadhesive potential. Eur. J. Pharm. Sci., 63, 132-139.
  84. Hauptstein, S.; Hintzen, F.; Müller, C.; Ohm, M.; Bernkop-Schnürch, A. (2014). Development and in vitro evaluation of a buccal drug delivery system based on preactivated thiolated pectin. Drug Dev. Ind. Pharm., 40, 1530-1537.
  85. Hintzen, F.; Perera, G.; Hauptstein, S.; Müller, C.; Laffleur, F.; Bernkop-Schnürch, A. (2014). In vivo evaluation of an oral self-microemulsifying drug delivery system (SMEDDS) for leuprorelin. Int. J. Pharm., 472, 20-26.
  86. Laffleur, F.; Hintzen, F.; Shahnaz, G.; Rahmat, D.; Leithner, K.; Bernkop-Schnürch, A. (2014). Development and in vitro evaluation of slippery nanoparticles for enhanced diffusion through native mucus. Nanomedicine, 9, 387-396.
  87. Millotti, G.; Laffleur, F.; Perera, G.; Vigl, C.; Pickl, K.; Sinner, F.; Bernkop-Schnürch, A. (2014). In vivo evaluation of thiolated chitosan tablets for oral insulin delivery. J. Pharm. Sci., 103, 3165-3170.
  88. Millotti, G.; Vetter, A.; Leithner, K.; Sarti, F.; Shahnaz-Bano, G.; Augustijns, P.; Bernkop-Schnürch, A. (2014). Development of thiolated poly(acrylic acid) microparticles for the nasal administration of exenatide. Drug Dev. Ind. Pharm., 40, 1677-1682.
  89. Müller, C.; Perera, G.; König, V.; Bernkop-Schnürch, A. (2014). Development and in vivo evaluation of papain-functionalized nanoparticles. Eur. J. Pharm. Biopharm., 87, 125-131.
  90. Nowak, J.; Laffleur, F.; Bernkop-Schnürch, A. (2014). Preactivated hyaluronic acid: A potential mucoadhesive polymer for vaginal delivery. Int. J. Pharm., 478, 383-389.
  91. Pereira de Sousa, I.; Bernkop-Schnürch, A. (2014). Pre-systemic metabolism of orally administered drugs and strategies to overcome it. J. Control. Rel., 192, 301-309.
  92. Samaridou, E.; Karidi, K.; Pereira de Sousa, I.; Cattoz, B.; Griffiths, P.; Kammona, O.; Bernkop-Schnürch, A.; Kiparissides. C. (2014). Enzyme-Functionalized PLGA Nanoparticles with Enhanced Mucus Permeation Rate. Nano LIFE, 4, 1441013
  93. Waldner, C.; Friedl, H.E.; Dünnhaupt, S.; Köllner, S.; Leonaviciute, G.; Bernkop-Schnürch, A. (2014). Development of a dosage form for accelerated release. Int. J. Pharm., 471, 189-196.
  94. Barthelmes, J.; Dünnhaupt, S.; Unterhofer, S.; Perera, G.; Schlocker, W.; Bernkop-Schnürch, A. (2013). Thiolated particles as effective intravesical drug delivery systems for treatment of bladder-related diseases. Nanomedicine, 8, 65-75.
  95. Friedl, H.; Dünnhaupt, S.; Hintzen, F.; Waldner, C.; Parikh, S.; Pearson, J.P.; Wilcox, M.D.; Bernkop-Schnürch, A. (2013). Development and evaluation of a novel mucus diffusion test system approved by self-nanoemulsifying drug delivery systems. J. Pharm. Sci., 102, 4406-4413.
  96. Friedl, H.E.; Dünnhaupt, S.; Waldner, C.; Bernkop-Schnürch, A. (2013). Preactivated thiomers for vaginal drug delivery vehicles. Biomaterials, 34, 7811-7818.
  97. Gradauer, K.; Barthelmes, J.; Vonach, C.; Almer, G.; Mangge, H.; Teubl, B.; Roblegg, E.; Dünnhaupt, S.; Fröhlich, E.; Bernkop-Schnürch, A.; Prassl, R. (2013). Liposomes coated with thiolated chitosan enhance oral peptide delivery to rats. J. Control. Rel., 172, 872-878.
  98. Gradauer, K.; Dünnhaupt, S.; Vonach, C.; Szöllösi, H.; Pali-Schöll, I.; Mangge, H.; Jensen-Jarolim, E.; Bernkop-Schnürch, A.; Prassl, R. (2013). Thiomer-coated liposomes harbor permeation enhancing and efflux pump inhibitory properties. J. Control. Rel., 165, 207-215.
  99. Hauptstein, S.; Müller, C.; Dünnhaupt, S.; Laffleur, F.; Bernkop-Schnürch, A. (2013). Preactivated thiomers: Evaluation of gastroretentive minitablets. Int. J. Pharm., 456, 473-479.
  100. Hintzen, F.; Hauptstein, S.; Perera, G.; Bernkop-Schnürch, A. (2013). Synthesis and in vitro characterization of entirely S-protected thiolated pectin for drug delivery. Eur. J. Pharm. Biopharm., 85, 1266-1273.
  101. Hintzen, F.; Laffleur, F.; Sarti, F.; Müller, C.; Bernkop-Schnürch, A. (2013). In vitro and ex vivo evaluation of an intestinal permeation enhancing self-microemulsifying drug delivery system (SMEDDS). J. Drug Del.Sci. Tech., 23, 261-267.
  102. Laffleur, F.; Hintzen, F.; Rahmat, D.; Shahnaz, G.; Millotti, G.; Bernkop-Schnürch, A. (2013). Enzymatic degradation of thiolated chitosan. Drug Dev. Ind. Pharm., 39, 1531-1539
  103. Laffleur, F.; Shahnaz, G.; Islambulchilar, Z.; Bernkop-Schnürch, A. (2013). Design and in vitro evaluation of a novel polymeric excipient for buccal applications. Future Med. Chem., 5, 511-522.
  104. Müller, C.; Leithner, K.; Hauptstein, S.; Hintzen, F.; Salvenmoser, W.; Bernkop-Schnürch, A. (2013). Preparation and characterization of mucus-penetrating papain/polyacrilic acid nanoparticles for oral drug delivery applications. J. Nanopart. Res., 15, 1353-1365.
  105. Müller, C.; Ma, B.N.; Gust, R.; Bernkop-Schnürch, A. (2013). Thiopyrazole preactivated chitosan: Combining mucoadhesion and drug delivery. Acta Biomater., 9, 6585-6593.
  106. Rahmat, D.; Müller, C.; Barthelmes, J.; Shahnaz, G.; Martien, R.; Bernkop-Schnürch, A. (2013). Thiolated hydroxyethyl cellulose: Design and in vitro evaluation of mucoadhesive and permeation enhancing nanoparticles. Eur. J. Pharm. Biopharm., 83, 149-155.
  107. Rahmat, D.; Müller, C.; Shahnaz, G.; Laffleur, F.; Leithner, K.; Khan, M.I.; Martien, R.; Bernkop-Schnürch, A. (2013). HEC-cysteamine particles: influence of particle size, zeta potential, morphology and sulfhydryl groups on permeation enhancing properties. Drug Dev. Ind. Pharm., 39, 1338-1345.
  108. Sakloetsakun, D.; Dünnhaupt, S.; Barthelmes, J.; Perera, G.; Bernkop-Schnürch, A. (2013). Combining two technologies: Multifunctional polymers and self-nanoemulsifying drug delivery system (SNEDDS) for oral insulin administration. Int. J. Biol. Macromol., 61, 363-372.
  109. Sarti, F.; Müller, C.; Iqbal, J.; Perera, G.; Laffleur, F.; Bernkop-Schnürch, A. (2013). Development and in vivo evaluation of an oral vitamin B12 delivery system. Eur. J. Pharm. Biopharm., 84, 132-137.
  110. Shahnaz, G.; Kremser, C.; Reinisch, A.; Vetter. A.; Laffleur, F.; Rahmat, D.; Iqbal, J.; Dünnhaupt, S.; Salvenmoser, W.; Tessadri, R.; Griesser, U.; Bernkop-Schnürch, A. (2013). Efficient MRI labeling of endothelial progenitor cells: Design of thiolated surface stabilized superparamagnetic iron oxide nanoparticles. Eur. J. Pharm. Biopharm., 85, 346-355.
  111. Boonpisuttinant, K.; Manosroi, A.; Rahmat, D.; Manosroi, J. (2012). In Vitro Intestinal Membrane Permeation Enhancement of Thai Anti-Cancer Recipe Aqueous Extracts Loaded inThiolated-Chitosan Nanoparticles. Adv. Sci. Lett. 16, 183-192.
  112. Dünnhaupt, S.; Barthelmes, J.; Iqbal, J.; Perera, G.; Thurner, C.C.; Friedl, H.; Bernkop-Schnürch, A. (2012). In vivo evaluation of an oral drug delivery system for peptides based on S-protected thiolated chitosan. J. Control. Rel., 160, 477-485.
  113. Dünnhaupt, S.; Barthelmes, J.; Rahmat, D.; Leithner, K.; Thurner, C.C.; Friedl, H.; Bernkop-Schnürch, A. (2012). S-protected thiolated chitosan for oral delivery of hydrophilic macromolecules: Evaluation of permeation enhancing and efflux pump inhibitory properties. Mol. Pharm., 9, 1331-1341.
  114. Dünnhaupt, S.; Barthelmes, J.; Thurner, C.C.; Waldner, C.; Sakloetsakun, D.; Bernkop-Schnürch, A. (2012). S-protected thiolated chitosan: synthesis and in vitro characterization. Carbohydr. Polym., 90, 765-772.
  115. Erb, R.; Leithner, K.; Bernkop-Schnürch, A.; Oberacher, H. (2012). Phosphorothioate Oligonucleotide Quantification by μ-Liquid Chromatography-Mass Spectrometry. AAPS Journal, 14, 728-737.
  116. Gradauer, K.; Vonach, C.; Leitinger, G.; Kolb, D.; Fröhlich, E.; Roblegg, E.; Bernkop-Schnürch, A.; Prassl, R. (2012). Chemical coupling of thiolated chitosan to preformed liposomes improves mucoadhesive properties. Int. J. Nanomedicine, 7, 2523-2534.
  117. Hauptstein, S.; Bernkop-Schnürch, A. (2012). Thiomers and thiomer-based nanoparticles in protein and DNA drug delivery. Expert Opin. Drug Deliv., 9, 1069-1081.
  118. Hintzen, F.; Laffleur, F.; Sakloetsakun, D.; Leithner, K.; Bernkop-Schnürch, A. (2012). In situ gelling properties of anionic thiomers. Drug Dev. Ind. Pharm., 38, 1479-1485.
  119. Hintzen, F.; Laffleur, F.; Sarti, F.; Shahnaz, G.; Bernkop-Schnürch, A. (2012). Thiomers: Influence of molar mass on in situ gelling properties. Int. J. Pharm., 436, 120-126.
  120. Iqbal, J.; Shahnaz, G.; Dünnhaupt, S.; Müller, C.; Hintzen, F.; Bernkop-Schnürch, A. (2012). Preactivated thiomers as mucoadhesive polymers for drug delivery. Biomaterials, 33, 1528-1535.
  121. Iqbal, J.; Shahnaz, G.; Perera, G.; Hintzen, F.; Sarti, F.; Bernkop-Schnürch, A. (2012). Thiolated chitosan: Development and in vivo evaluation of an oral delivery system for leuprolide. Eur. J. Pharm. Biopharm., 80, 95-102.
  122. Laffleur, F.; Bernkop-Schnürch, A. (2012). Thiomers: promising platform for macromolecular drug delivery. Future Med. Chem., 4, 2205-2216.
  123. Müller, C.; Rahmat, D.; Sarti, F.; Leithner, K.; Bernkop-Schnürch, A. (2012). Immobilization of 2-mercaptoethylamine on oxidized chitosan: a substantially mucoadhesive and permeation enhancing polymer. J. Mater. Chem., 22, 3899-3908.
  124. Müller, C.; Verroken, A.; Iqbal, J.; Bernkop-Schnürch, A. (2012). Thiolated Chitosans: in vitro comparison of mucoadhesive properties. J. Appl. Polym. Sci., 124, 5046-5055.
  125. Rahmat, D.; Khan, M.I.; Shahnaz, G.; Sakloetsakun, D.; Perera, G.; Bernkop-Schnürch, A. (2012). Synergistic effects of conjugating cell penetrating peptides and thiomers. On non-viral transfection efficiency. Biomaterials, 33, 2321-2326.
  126. Rahmat, D.; Sakloetsakun, D.; Shahnaz, G.; Sarti, F.; Laffleur, F.; Bernkop-Schnürch, A. (2012). HEC-cysteamine conjugates: Influence of degree of thiolation on efflux pump inhibitory and permeation enhancing properties. Int. J. Pharm., 422, 40-46.
  127. Sakloetsakun, D.; Dünnhaupt, S.; Barthelmes, J.; Pfaller, W.; Bernkop-Schnürch, A. (2012). In situ crosslinkable thiolated chitosan as scaffold material for tissue engineering. Adv. Mat. Res., 506, 335-338.
  128. Sarti, F.; Iqbal, J.; Müller, C.; Shahnaz, G.; Rahmat, D.; Bernkop-Schnürch, A. (2012). Poly(acrylic acid)-cysteine for oral vitamin B12 delivery. Anal. Biochem., 420, 13-19.
  129. Shahnaz, G.; Iqbal, J.; Rahmat, D.; Perera, G.; Laffleur, F.; Rossi, D.; Bernkop-Schnürch, A. (2012). Development and in vivo characterization of a novel peptide drug delivery system providing extended plasma half life. J. Control. Rel., 157, 375-382.
  130. Shahnaz, G.; Vetter, A.; Barthelmes, J.; Rahmat, D.; Laffleur, F.; Iqbal, J.; Perera, G.; Schlocker, W.; Dünnhaupt, S.; Augustijns, P.; Bernkop-Schnürch, A. (2012). Thiolated chitosan nanoparticles for the nasal administration of leuprolide: Bioavailability and pharmacokinetic characterization. Int. J. Pharm., 428, 164-170.
  131. Solhi, L.; Schönbichler, S.A.; Dünnhaupt, S.; Barthelmes, J.; Friedl, H.; Huck, C.W.; Bernkop-Schnürch, A. (2012). Synthesis and In Vitro Characterization of a Preactivated Thiomer via Polymerization Reaction. Biomacromolecules, 13, 3054-3063.
  132. Vetter, A.; Augustijns, P.; Bernkop-Schnürch, A. (2012). Solubilizing agents in nasal formulations and their effect on ciliary beat frequency. Toxicol. in vitro, 26, 150-156.
  133. Wang, X.; Iqbal, J.; Rahmat, D.; Bernkop-Schnürch, A. (2012). Preactivated thiomers: Permeation enhancing properties. Int. J. Pharm., 438, 217-224.
  134. Baloglu, E.; Ay Senyıgıt, Z.; Karavana, S.Y.; Vetter, A.; Metın, D.Y.; Hilmioglu Polat, S.; Guneri, T.; Bernkop-Schnürch, A. (2011). In vitro evaluation of mucoadhesive vaginal tablets of antifungal drugs prepared with thiolated polymer and development of a new dissolution technique for vaginal formulations Chem.Pharm.Bull., 59, 952-958.
  135. Barthelmes, J.; Dünnhaupt, S.; Hombach, J.; Bernkop-Schnürch, A. (2011). Thiomer nanoparticles: Stabilization via covalent cross-linking. Drug Deliv., 18, 613-619.
  136. Barthelmes, J.; Perera, G.; Hombach, J.; Dünnhaupt, S.; Bernkop-Schnürch, A. (2011). Development of a mucoadhesive nanoparticulate drug delivery system for a targeted drug release in the bladder. Int. J. Pharm., 416, 339-345.
  137. Dudas, J.; Idler, C.; Sprinzl,G.; Bernkop-Schnuerch, A.; Riechelmann, H. (2011). Identification of HN-1-Peptide Target in Head and Neck Squamous Cell Carcinoma Cells. ISRN Oncology Article ID 140316, 10 pages
  138. Dünnhaupt, S.; Barthelmes, J.; Hombach, J.; Sakloetsakun, D.; Arkhipova, V.; Bernkop-Schnürch, A. (2011). Distribution of thiolated mucoadhesive nanoparticles on intestinal mucosa. Int. J. Pharm., 408, 191-199.
  139. Hoyer, H.; Hombach, J.; Perera, G.; Thaurer, M.; Bernkop-Schnürch, A. (2011). Synthesis and in vitro characterization of a novel PAA-ATP conjugate. Drug Dev. Ind. Pharm., 37, 300-309.
  140. Iqbal, J.; Sakloetsakun, D.; Bernkop-Schnürch, A. (2011). Thiomers: Inhibition of cytochrome P450 activity. Eur. J. Pharm. Biopharm., 78, 361-365.
  141. Iqbal, J.; Sarti, F.; Perera, G.; Bernkop-Schnürch, A. (2011). Development and in vivo evaluation of an oral drug delivery system for paclitaxel. Biomaterials, 32, 170-175.
  142. Iqbal, J.; Vigl, C.; Moser, G.; Gasteiger, M.; Perera, G.; Bernkop-Schnürch, A. (2011). Development and in vivo evaluation of a new oral nanoparticulate dosage form for leuprolide based on polyacrylic acid. Drug Deliv., 18, 432-440.
  143. Leithner, K.; Grabovac, V.; Albrecht, K.; Hombach, J.; Klima, G.; Bernkop-Schnürch, A. (2011). Permeation studies on freshly excised rat gastric mucosa: influence of pH. Drug Dev. Ind. Pharm., 37, 518-525.
  144. Llabot, J.M.; Salman, H.; Millotti, G.; Bernkop-Schnürch, A.; Allemandi, D.; Manuel Irache, J. (2011). Bioadhesive properties of poly(anhydride) nanoparticles coated with different molecular weights chitosan. J. Microencap., 28, 455-463.
  145. Martien, R.; Hoyer, H.; Perera, G.; Bernkop-Schnürch, A. (2011). An oral oligonucleotide delivery system based on a thiolated polymer: Development and in vitro evaluation. Eur. J. Pharm. Biopharm., 78, 355-360.
  146. Millotti, G.; Perera, G.; Vigl, C.; Pickl, K.; Sinner, F.M.; Bernkop-Schnürch, A. (2011). The use of chitosan-6-mercaptonicotinic acid nanoparticles for oral peptide drug delivery. Drug Deliv., 18, 190-197.
  147. Palmberger, T.; Augustijns, P.; Vetter, A.; Bernkop-Schnürch, A. (2011). Safety assessment of thiolated polymers: effect on ciliary beat frequency in human nasal epithelial cells. Drug Dev. Ind. Pharm., 37, 1455-1462.
  148. Perera, G.; Barthelmes, J.; Vetter, A.; Krieg, C.; Uhlschmied, C.; Bonn, G.K.; Bernkop-Schnürch, A. (2011). Thiolated polycarbophil/glutathione: Defining its potential as a permeation enhancer for oral drug administration in comparison to sodium caprate. Drug Deliv., 18, 415-423.
  149. Rahmat, D.; Sakloetsakun, D.; Shahnaz, G.; Perera, G.; Kaindl, R.; Bernkop-Schnürch, A. (2011). Design and synthesis of a novel cationic thiolated polymer. Int. J. Pharm., 411, 10-17.
  150. Sakloetsakun, D.; Iqbal, J.; Millotti, G.; Vetter, A.; Bernkop-Schnürch, A. (2011). Thiolated chitosans: influence of various sulfhydryl ligands on permeation-enhancing and P-gp inhibitory properties. Drug Dev. Ind. Pharm., 37, 648-655.
  151. Sarti, F.; Barthelmes, J.; Iqbal, J.; Hintzen, F.; Bernkop-Schnürch, A. (2011). Intestinal enzymatic metabolism of drugs. J. Pharm. Pharmacol., 63, 392-399.
  152. Sarti, F.; Bernkop-Schnürch, A. (2011). Chitosan and Thiolated Chitosan. Adv. Polym. Sci., 243, 93-110.
  153. Sarti, F.; Perera, G.; Hintzen, F.; Kottib,K.; Karageorgioub, V.; Kammonab, O.; Kiparissides, C.; Bernkop-Schnürch, A. (2011). In vivo evidence of oral vaccination with PLGA nanoparticles containing the immunostimulant monophosphoryl lipid A. Biomaterials, 32, 4052-4057.
  154. Senyigit, Z.A.; Vetter, A.; Guneri, T.; Bernkop-Schnürch, A. (2011). A comprehensive in vitro and in vivo evaluation of thiolated matrix tablets as a gastroretentive delivery system. Drug Deliv., 18, 405-414.
  155. Shahnaz, G.; Hartl, M.; Barthelmes, J.; Leithner, K.; Sarti, F.; Hintzen, F.; Rahmat, D.; Salvenmoser, W.; Bernkop-Schnürch, A. (2011). Uptake of phenothiazines by the harvested chylomicrons ex vivo model: Influence of self-nanoemulsifying formulation design. Eur. J. Pharm. Biopharm., 79, 171-180.
  156. Vetter, A.; Reinisch, A.; Strunk, D.; Kremser, C.; Hahn, H.W.; Huck, C.W.; Ostermann, T.; Leithner, K.; Bernkop-Schnürch, A. (2011). Thiolated polyacrylic acid-modified iron oxide nanoparticles for in vitro labeling and MRI of stem cells. J. Drug Targ., 19, 562-572.
  157. Albrecht, K.; Greindl, M.; Deutel, B.; Kremser, C.; Wolf, C.; Talasz, H.; Stollenwerk, M.; Debbage, P.; Bernkop-Schnürch, A. (2010). In vivo investigation of thiomer-polyvinylpyrrolidon nanoparticles using magnetic resonance imaging. J. Pharm. Sci., 99, 2008-2017.
  158. Hoyer, H.; Schlocker, W.; Greindl, M.; Ostermann, T.; Bernkop-Schnürch, A. (2010). Preparation and evaluation of thiomer nanoparticles via high pressure homogenization. J. Microencap., 27, 487-495.
  159. Iqbal, J.; Hombach, J.; Matuszczak, B.; Bernkop-Schnürch, A. (2010). Design and in vitro evaluation of a novel polymeric P-glycoprotein (P-gp) inhibitor. J. Control. Rel., 147, 62-69.
  160. Millotti, G.; Hoyer, H.; Engbersen, J.F.J.; Bernkop-Schnürch, A. (2010). 6-mercaptonicotinamide- functionalized chitosan: A potential excipient for mucoadhesive drug delivery systems. J. Drug Del. Sci.Tech., 20, 181-186.
  161. Millotti, G.; Samberger, C.; Fröhlich, E.; Sakloetsakun, D.; Bernkop-Schnürch, A. (2010). Chitosan-4-mercaptobenzoic acid: synthesis and characterization of a novel thiolated chitosan. J. Mater. Chem., 20, 2432-2440.
  162. Perera, G.; Barthelmes, J.; Bernkop-Schnürch, A. (2010). Novel pectin-4-aminothiophenole conjugate microparticles for colon-specific drug delivery. J. Control. Rel., 145, 240-246.
  163. Perera, G.; Hombach, J.; Bernkop-Schnürch, A. (2010). Hydrophobic thiolation of pectin with 4-aminothiophenol: Synthesis and in vitro characterization. AAPS PharmSciTech., 11, 174-180.
  164. Sakloetsakun, D.; Perera, G.; Hombach, J.; Millotti, G.; Bernkop-Schnürch, A. (2010). The impact of vehicles on the mucoadhesive properties of orally administered nanoparticles: a cas. AAPS PharmSciTech., 11, 1185-1192.
  165. Sarti, F.; Staaf, A.; Sakloetsakun, D.; Bernkop-Schnürch, A. (2010). Thiolated hydroxyethylcellulose:synthesis and in vitro evaluation. Eur. J. Pharm. Biopharm., 76, 421-427.
  166. Senyigit, Z.A.; Vetter, A.; Guneri, T.; Bernkop-Schnürch, A. (2010). Gastroretentive particles formulated with thiomers: development and in vitro evaluation. J. Drug Targ., 18, 362-372.
  167. Shahnaz, G.; Perera, G.; Sakloetsakun, D.; Rahmat, D.; Bernkop-Schnürch, A. (2010). Synthesis, Characterization, Mucoadhesion and Biocompatibility of Thiolated Carboxymethyldextran-Cysteine Conjugate. J. Control. Rel., 144, 32-38.
  168. Vetter, A.; Bernkop-Schnürch, A. (2010). Nasal delivery of antisense oligonucleotides: in vitro evaluation of a thiomer/glutathione microparticulate delivery system. J. Drug Targ., 18, 303-312.
  169. Vetter, A.; Martien, R.; Bernkop-Schnürch, A. (2010). Thiolated polycarbophil as an adjuvant for permeation enhancement in nasal delivery of antisense oligonucleotides. J. Pharm. Sci., 99, 1427-1439.
  170. Vetter, A.; Perera, G.; Leithner, K.; Klima, G.; Bernkop-Schnürch, A. (2010). Development and in vivo bioavailability study of an oral fondaparinux delivery system. Eur. J. Pharm. Sci., 41, 489-497.
  171. Biasutto, L.; Marotta, E.; Mattarei, A.; Beltramello, S.; Caliceti, P.; Salmaso, S. Bernkop-Schnürch, A.; Garbisa, S; Zoratti, M.; Paradisi, C. (2009). Absorption and metabolism of resveratrol carboxyesters and methanesulfonate by explanted rat intestinal segments. Cellular Physiology and Biochemistry, 24, 557-566.
  172. Figueiras, A.; Hombach, J.; Veiga, F.; Bernkop-Schnürch A. (2009). In vitro evaluation of natural and methylated cyclodextrins as buccal permeation enhancing systems for omeprazole delivery. Eur. J. Pharm. Biopharm., 71, 339-345.
  173. Greindl, M.; Föger, F.; Hombach, J.; Bernkop-Schnürch, A. (2009). In vivo evaluation of thiolated poly(acrylic acid) as a drug absorption modulator for MRP2 efflux pump substrates. Eur. J. Pharm. Biopharm., 72, 561-566.
  174. Hombach, J.; Bernkop-Schnürch, A. (2009). Chitosan solutions and particles: Evaluation of their permeation enhancing potential on MDCK cells used as blood brain barrier model. Int. J. Pharm., 376, 104-109.
  175. Hombach, J.; Palmberger, T.; Bernkop-Schnürch, A. (2009). Development and in vitro evaluation of a mucoadhesive vaginal delivery system for nystatin. J. Pharm. Sci., 98, 555-564.
  176. Hoyer, H.; Greindl, M.; Bernkop-Schnürch, A. (2009). Design and in vivo evaluation of a patch system based on thiolated polymers. J. Pharm. Sci., 98, 620-627.
  177. Millotti, G.; Samberger, C.; Fröhlich, E.; Bernkop-Schnürch, A. (2009). Chitosan-graft-6-mercaptonicotinic acid: synthesis, characterization, and biocompatibility. Biomacromolecules, 10, 3023-3027.
  178. Perera, G.; Greindl, M.; Palmberger, T.; Bernkop-Schnürch, A. (2009). Insulin-loaded poly(acrylic acid)-cysteine nanoparticles: stability studies towards digestive enzymes of the intestine. Drug Deliv., 16, 254-260.
  179. Sakloetsakun D.; Hombach J.; Bernkop-Schnürch, A. (2009). In situ gelling properties of chitosan-thioglycolic acid conjugate in the presence of oxidizing agents. Biomaterials, 30, 6151-6157.
  180. Thaurer, M.H.; Deutel, B.; Schlocker, W.; Bernkop-Schnürch, A. (2009). Development of nanoparticulate drug delivery systems based on thiolated poly(acrylic acid). J. Microencap., 26, 187-194.
  181. Vigl, C.; Leithner, K.; Albrecht, K.; Bernkop-Schnürch, A. (2009). The efflux pump inhibitory properties of (thiolated) polyallylamines. J. Drug Del. Sci.Tech., 19, 405-411.
  182. Werle, M.; Takeuchi, H.; Bernkop-Schnürch, A. (2009). Modified Chitosans for oral drug delivery. J. Pharm. Sci., 98, 1643-1656.
  183. Deutel, B.; Greindl, M.; Thaurer, M.; Bernkop-Schnürch, A. (2008). Novel insulin thiomer nanoparticles: in vivo evaluation of an oral drug delivery system. Biomacromolecules, 9, 278-285.
  184. Föger, F.; Kopf, A.; Loretz, B.; Albrecht, K.; Bernkop-Schnürch, A. (2008). Correlation of in vitro and in vivo models for the oral absorption of peptide drugs. Amino Acids, 35, 233-241.
  185. Föger, F.; Malaivijitnond,. S.; Wannaprasert, T.; Huck, C.; Bernkop-Schnürch, A.; Werle, M. (2008). Effect of a thiolated polymer on oral paclitaxel absorption and tumor growth in rats. J. Drug Targ., 16, 149-155.
  186. Grabovac, V.; Föger, F.; Bernkop-Schnürch, A. (2008). Design and in vivo evaluation of a patch delivery system for insulin based on thiolated polymers. Int. J. Pharm., 348, 169-174.
  187. Hombach, J.; Hoyer, H.; Bernkop-Schnürch, A. (2008). Thiolated chitosans: Development and in vitro evaluation of an oral tobramycin sulphate delivery system. Eur. J. Pharm. Sci., 33, 1-8.
  188. Hoyer, H.; Schlocker, W.; Kafedjiiski, K.; Bernkop-Schnürch, A. (2008). Preparation and evaluation of microparticles from thiolated polymers via air jet milling. Eur. J. Pharm. Biopharm., 69, 476-485.
  189. Kremser, C.; Albrecht, K.; Greindl, M.; Wolf, C.; Debbage, P.; Bernkop-Schnürch, A. (2008). In vivo determination of time and location at which mucoadhesive drug delivery systems disintegrate in the gastrointestinal tract. Magn. Reson. Imaging, 26, 638-643.
  190. Martien, R.; Loretz, B.; Sandbichler, A.M.; Bernkop-Schnürch, A. (2008). Thiolated chitosan nanoparticles: transfection study in the Caco-2 differentiated cell culture. Nanotechnology, 19, 045101 (9pp).
  191. Palmberger, T.; Hombach, J.; Bernkop-Schnürch, A. (2008). Thiolated chitosan: Development and in vitro evaluation of an oral delivery system for acyclovir. Int. J. Pharm., 348, 54-60.
  192. Petter, Ch.; Heigl, N.; Bachmann, St.; Huck-Pezzei, V.; Najam-ol-Haq, M.; Bakry, R.; Bernkop-Schnürch, A.; Bonn, G.; Huck, Ch. (2008). Near infrared spectroscopy compared to liquid chromatography coupled to mass spectrometry and capillary electrophoresis as a detection tool for peptide reaction monitoring. Amino Acids, 34, 605-616.
  193. Schmitz, T.; Grabovac, V.; Palmberger, T.F.; Hoffer, M.H.; Bernkop-Schnürch, A. (2008). Synthesis and characterization of a chitosan-N-acetyl cystein conjugate. Int. J. Pharm., 347, 79-85.
  194. Schmitz, T.; Hombach, J.; Bernkop-Schnürch, A. (2008). Chitosan-N-acetyl cysteine conjugates: In vitro evaluation of permeation enhancing and P-glycoprotein inhibiting properties. Drug Deliv., 15, 245-252.
  195. Tsiklauri, L.; Hoyer, H.; Chkhikvadze, G.; Vachnadze, V.; Tsagareishvili, G.; Bakuridze, A.; Bernkop-Schnürch, A. (2008). Role of P-glycoproteins (P-gp) in the transepithelial transport of indoline alkaloids from Vinca herbaceae. Khim.-Farm. Zhurnal, 42, 29-32.
  196. Werle, M.; Kolmar, H.; Albrecht, R.; Bernkop-Schnürch, A. (2008). Characterisation of the barrier caused by luminally secreted gastro-intestinal proteolytic enzymes for two novel cystine-knot microproteins. Amino Acids, 35, 195-200.
  197. Bernkop-Schnürch, A. and Schmitz, Th. (2007). Presystemic metabolism of orally administered peptide drugs and strategies to overcome it. Curr. Drug Metab., 8, 509-517.
  198. Föger, F., Kafedjiiski, K., Hoyer, H., Loretz, B. and Bernkop-Schnürch, A. (2007). Enhanced transport of P-glycoprotein substrate saquinavir in presence of thiolated chitosan. J. Drug Targ., 15, 132-139.
  199. Grabovac, V. and Bernkop-Schnürch, A. (2007). Development and in vitro evaluation of surface modified poly(lactide-co-glycolide) nanoparticles with chitosan-4-thiobutylamidine. Drug Dev. Ind. Pharm., 33, 767-774.
  200. Grabovac, V., Schmitz, Th., Föger, F. and Bernkop-Schnürch, A. (2007). Papain: An effective permeation enhancer for orally administered low molecular weight heparin. Pharm. Res., 24, 1001-1006.
  201. Greimel, A., Del Curto, M. D., D’Antonio, M. and Bernkop-Schnürch, A. (2007). Transport characteristics of a beta sheet breaker peptide across excised bovine nasal mucosa. Drug Dev. Ind. Pharm., 33, 71-77.
  202. Greimel, A., Werle, M. and Bernkop-Schnürch, A. (2007). Oral peptide delivery: in vitro evaluation of thiolated alginate / poly(acrylic acid) microparticles. J. Pharm. Pharmacol., 59, 1191-1198.
  203. Hoyer, H., Föger, F., Kafedjiiski, K., Loretz, B., and Bernkop-Schnürch, A. (2007). Design and evaluation of a new gastrointestinal mucoadhesive patch system containing chitosan-glutathione. Drug Dev. Ind. Pharm., 33, 1289-1296.
  204. Kafedjiiski, K., Föger, F., Hoyer, H., Werle, M. and Bernkop-Schnürch, A. (2007). Evaluation of in vitro enzymatic degradation of various thiomers and cross-linked thiomers. Drug Dev. Ind. Pharm., 33, 199-208.
  205. Kafedjiiski, K., Jetti, R., Föger, F., Hoyer, H., Werle, M., Hoffer, M., and Bernkop-Schnürch, A. (2007). Synthesis and in vitro evaluation of thiolated hyaluronic acid for mucoadhesive drug delivery. Int. J. Pharm., 343, 48-58.
  206. Loretz, B. and Bernkop-Schnürch, A. (2007). In vitro cytotoxity testing of non-thiolated and thiolated chitosan nanoparticles for oral gene delivery. Nanotoxicology, 1, 139-148.
  207. Loretz, B., Thaler, M. and Bernkop-Schnürch, A. (2007). Role of sulfhydryl groups in transfection? A case study with chitosan-NAC nanoparticles. Bioconjugate Chemistry, 18, 1028-1035.
  208. Martien, R., Loretz, B., Thaler, M., Majzoob, S. and Bernkop-Schnürch, A. (2007). Chitosan-thioglycolic acid conjugate: An alternative carrier for oral non-viral gene delivery? J. Biomed. Mat. Res. A., 82, 1-9.
  209. Palmberger, T. F., Albrecht, K, Loretz, B., and Bernkop-Schnürch, A. (2007). Thiolated polymers: Evaluation of the influence of the amount of covalently attached l-cysteine to poly(acrylic acid). Eur. J. Pharm. Biopharm., 66, 405-412.
  210. Schmitz, T., Bravo-Osuna, I., Vauthier, C., Ponchel, G., Loretz, B. and Bernkop-Schnürch, A. (2007). Development and in vitro evaluation of a thiomer-based nanoparticulate gene delivery system. Biomaterials, 28, 524-531. 2006
  211. Werle, M., Kafedjiiski, K., Kolmar H. and Bernkop-Schnürch, A. (2007). Evaluation and improvement of the properties of the novel cystine-knot microprotein McoEeTI for oral administration. Int. J. Pharm., 332, 72-79.
  212. Werle, M., Kolmar, H., and Bernkop-Schnürch, A. (2007). Relation between scaffold size and membrane bound enzyme caused degradation of two novel cystine knot microproteins. Letters in Drug Design & Discovery, 4, 33-36.
  213. Albrecht, K., Greindl, M.; Kremser, C.; Wolf, C.; Debbage, P. and Bernkop-Schnürch, A. (2006). Comparative in vivo mucoachesion studies of thiomer formulations using magnetic resonance imaging and fluorescence detection. J. Control. Rel., 115, 78-84.
  214. Albrecht, K., Zirm, E.J., Palmberger, T.F., Schlocker, W. and Bernkop-Schnürch, A. (2006). Preparation of thiomer microparticles and in vitro evaluation of parameters influencing their mucoadhesive properties. Drug Dev. Ind. Pharm., 32, 1149-1157.
  215. Bernkop-Schnürch, A. (2006). Oral delivery of therapeutic peptides: Barriers and strategies to overcome them. J. Drug Targ., 14, 107-108.
  216. Bernkop-Schnürch, A., Heinrich, A. and Greimel, A. (2006). Development of a novel method for the preparation of submicron particles based on thiolated chitosan. Eur. J. Pharm. Biopharm., 63, 166-172.
  217. Bernkop-Schnürch, A., Obermair, K., Greimel, A. and Palmberger Th. F. (2006). In vitro evaluation of the potential of thiomers for the nasal administration of Leu-enkephalin. Amino Acids, 30, 417-423.
  218. Bernkop-Schnürch, A., Weithaler, A., Albrecht, K. and Greimel, A. Thiomers: Preparation and in vitro evaluation of a mucoadhesive nanoparticulate drug delivery system (2006). Thiomers: Preparation and in vitro evaluation of a mucoadhesive nanoparticulate drug delivery system. Int. J. Pharm., 317, 76-81.
  219. Bravo-Osuna, I., Schmitz, Th., Bernkop-Schnürch, A., Vauthier, Ch. And Ponchel, G. (2006). Elaboration and characterization of thiolated chitosan-coated acrylic nanoparticles. Int. J. Pharm., 316, 170-175.
  220. Föger, F., Hoyer, H., Kafedjiiski, K., Thaurer, M. and Bernkop-Schnürch, A (2006). In vivo comparison of various polymeric and low molecular mass inhibitors of intestinal P-glycoprotein. Biomaterials, 27, 5855-5860.
  221. Föger, F., Noonpakdee, W., Loretz, B., Joojuntr, S., Salvenmoser, W. and Bernkop-Schnürch, A. (2006). Inhibition of malarial topoisomerase II in Plasmodium falciparum by antisense nanoparticles. Int. J. Pharm., 319, 139-146.
  222. Föger, F., Schmitz, T. and Bernkop-Schnürch, A. (2006). In vivo evaluation of an oral delivery system for P-gp substrates based on thiolated chitosan. Biomaterials, 27, 4250-4255.
  223. Grabovac, V. and Bernkop-Schnürch, A. (2006). Improvement of the intestinal membrane permeability of low molecular weight heparin by complexation with stem bromelain. Int. J. Pharm., 326, 153-159.
  224. Greimel, A., Del Curto, M. D., D’Antonio, M., Palmberger, Th., Sprinzl, G. M. and Bernkop-Schnürch, A. (2006). In vitro evaluation of thiomer microparticles for nasal drug delivery. J. Drug Del. Sci.Tech., 16, 103-108.
  225. Greindl, M. and Bernkop-Schnürch, A. (2006). Development of a novel method for the preparation of thiolated polyacrylic acid nanoparticles. Pharm. Res., 23, 2183-2189.
  226. Huck, Ch. W., Pezzei, V., Schmitz, Th., Bonn, G.K. and Bernkop-Schnürch, A. (2006). Oral peptide delivery: Are there remarkable effects on drugs through sulfhydryl conjugation? J. Drug Targ., 14, 117-125.
  227. Kafedjiiski, K., Hoffer, M., Werle, M.and Bernkop-Schnürch, A. (2006). Improved synthesis and in vitro characterization of chitosan-thioethylamidine conjugate. Biomaterials, 27, 127-135.
  228. Krauland, A., Guggi, D., and Bernkop-Schnürch, A. (2006). Thiolated chitosan microparticles: A vehicle for nasal peptide drug delivery. Int. J. Pharm., 307, 270-277.
  229. Krauland, A., Leitner, V. M., Grabovac, V. and Bernkop-Schnürch, A. (2006). In vivo evaluation of a nasal insulin delivery system based on thiolated chitosan. J. Pharm. Sci., 95, 2463-2472.
  230. Langoth, N., Kahlbacher, H., Schöffmann, G., Schmerold, I., Schuh, M., Franz, S., Kurka, P. and Bernkop-Schnürch, A. (2006). Thiolated chitosans: Design and in vivo evaluation of a mucoadhesive buccal peptide drug delivery system. Pharm. Res., 23, 573-579.
  231. Loretz, B. and Bernkop-Schnürch, A. (2006). In vitro evaluation of chitosan-EDTA conjugate polyplexes as nanoparticulate gene delivery system. AAPS Journal, 8, E756-E764.
  232. Loretz, B., Föger, F. A., Werle, M. and Bernkop-Schnürch, A. (2006). Oral gene delivery: Strategies to improve stability of pDNA towards intestinal digestion. J. Drug Targ., 14, 311-319.
  233. Majzoob, S., Atyabi, F., Dorkoosh, F., Kafedjiiski, K., Loretz, B., and Bernkop-Schnürch, A. (2006). Pectin-cysteine conjugate: synthesis and in-vitro evaluation of its potential for drug delivery. J. Pharm. Pharmacol., 58, 1601-1610.
  234. Martien, R., Loretz, B., and Bernkop-Schnürch, A. (2006). Oral gene delivery: Design of polymeric carrier systems shielding towards intestinal enzymatic attack. Biopolymers, 83, 327-336.
  235. Schlocker, W., Gschließer, S. and Bernkop-Schnürch, A. (2006). Evaluation of the potential of air jet milling for peptide-loaded microparticle preparation. Eur. J. Pharm. Biopharm., 62, 260-266.
  236. Schmitz, T., Huck, C.W. and Bernkop-Schnürch, A. (2006). Characterisation of the thiol-disulphide chemistry of desmopressin by LC, μ-LC, LC-ESI-MS and Maldi-Tof. Amino Acids, 30, 35-42.
  237. Werle, M. and Bernkop-Schnürch, A. (2006). Strategies to improve plasma half life time of peptide and protein drugs. Amino Acids, 30, 351-367.
  238. Werle, M., Samhaber A. and Bernkop-Schnürch, A. (2006). Degradation of teriparatide by gastro-intestinal proteolytic enzymes. J. Drug Targ., 14, 109-115.
  239. Werle, M., Schmitz, Th., Huang, H.-L., Wentzel, A., Kolmar, H. and Bernkop-Schnürch A. (2006). The potential of cystine-knot microproteins as novel pharmacophoric scaffolds in oral peptide drug delivery. J. Drug Targ., 14, 137-146.
  240. Bernkop-Schnürch, A. (2005). Mucoadhesive polymers: strategies, achievements and future challenges. Adv. Drug Del. Rev., 57, 1553-1555.
  241. Bernkop-Schnürch, A., Pinter, Y., Guggi, D., Kahlbacher, H., Schöffmann, G., Schuh, M., Schmerold, I., Del Curto, M.D., D'Antonio, M., Esposito, P. and Huck, Ch. (2005). The use of thiolated polymers as carrier matrix in oral peptide delivery - Proof of concept. J. Control. Rel., 106, 26-33.
  242. Grabovac, V., Guggi, D., and Bernkop-Schnürch, A. (2005). Comparison of the mucoadhesive properties of various polymers. Adv. Drug Del. Rev., 57, 1713-1723.
  243. Guggi, D. and Bernkop-Schnürch, A. (2005). Improved paracellular uptake by the combination of different types of permeation enhancers. Int. J. Pharm., 288, 141-150.
  244. Imam, M.E. and Bernkop-Schnürch, A. (2005). Controlled drug delivery systems based on thiolated chitosan microspheres. Drug Dev. Ind. Pharm., 31, 557-565.
  245. Kafedjiiski, K., Föger, F., Werle, M. and Bernkop-Schnürch, A. (2005). Synthesis and in vitro evaluation of a novel chitosan-glutathione conjugate. Pharm. Res., 22, 1480-1488.
  246. Kafedjiiski, K., Krauland, A.H., Hoffer, M.H. and Bernkop-Schnürch, A. (2005). Synthesis and in vitro evaluation of a novel thiolated chitosan. Biomaterials, 26, 819-826.
  247. Kafedjiiski, K., Werle, M., Föger, F. and Bernkop-Schnürch, A. (2005). Synthesis and in vitro characterization of a novel poly(acrylic acid)-glutathione conjugate. J. Drug Del. Sci.Tech., 15, 411-417.
  248. Krauland, A., Hoffer, M.H., and Bernkop-Schnürch, A. (2005). Viscoelastic properties of a new in situ gelling thiolated chitosan conjugate. Drug Dev. Ind. Pharm., 31, 885-893.
  249. Langoth, N., Bernkop-Schnürch, A. and Kurka, P. (2005). The inhibitory effect of glutathione towards buccal enzymatic degradation of therapeutic peptides (leu-enkephalin, luteinizing hormone-releasing hormone and pituitary adenylate cyclase activating peptide). J. Drug Del. Sci.Tech., 15, 435-438.
  250. Langoth, N., Bernkop-Schnürch, A. and Kurka, P. (2005). In vitro evaluation of various buccal permeation enhancing systems for PACAP (pituitary adenylate cyclase-activating polypeptide). Pharm. Res., 22, 2045-2050.
  251. Langoth, N., Kalbe, J. and Bernkop-Schnürch, A. (2005). Development of a mucoadhesive and permeation enhancing buccal delivery system for PACAP (pituitary adenylate cyclase-activating polypeptide). Int. J. Pharm., 296, 103-111.
  252. Maculotti, K., Genta, I., Perugini, P., Imam,M., Bernkop-Schnürch, A. and Pavanetto, F. (2005). Preparation and in vitro evaluation of thiolated chitosan microparticles. J. Microencap., 22, 459-470.
  253. Schmitz, T., Leitner, V., Bernkop-Schnürch, A. (2005). Oral heparin delivery: Design and in vivo evaluation of a stomach-targeted mucoadhesive delivery system. J. Pharm. Sci., 94, 966-973.
  254. Werle, M., Schmitz T., Wentzel A., Kolmar H. and Bernkop-Schnürch A. (2005). In vitro evaluation of the enzymatic stability and permeation behaviour of microbodies: novel carriers for oral peptide drug delivery? Pharmacia, 52, 126-127.
  255. Bernkop-Schnürch, A., Guggi, D., and Pinter, Y. (2004). Thiolated chitosans: development and in vivo evaluation of a mucoadhesive permeation enhancing oral drug delivery system. J. Control. Rel., 94, 177-186.
  256. Bernkop-Schnürch, A., König, V., Leitner, V., Krauland, A. and Brodnik, I. (2004). Preparation and characterisation of thiolated poly(methacrylic acid) - starch compositions. Eur. J. Pharm. Biopharm., 57, 219-224.
  257. Bernkop-Schnürch, A., Leitner, V., and Moser, V. (2004). Synthesis and in vitro characterisation of a poly(acrylic acid)-homocysteine conjugate. Drug Dev. Ind. Pharm., 30, 1-8.
  258. Bernkop-Schnürch, A., Reich-Rohrwig, E., Marschütz, M., Schuhbauer H. and Kratzel, M. (2004). Development of a sustained release dosage form for alpha-lipoic acid. II. Evaluation in human volunteers. Drug Dev. Ind. Pharm., 30, 35-42.
  259. Bernkop-Schnürch, A., Schuhbauer H., Clausen, A.E. and Hanel, R. (2004). Development of a sustained release dosage form for alpha-lipoic acid. I. Design and in vitro evaluation. Drug Dev. Ind. Pharm., 30, 27-34.
  260. Caliceti, P. Salmaso, S., Walker, G. and Bernkop-Schnürch, A. (2004). Development and in vivo evaluation of an oral insulin-PEG delivery system. Eur. J. Pharm. Sci., 22, 315-323.
  261. Guggi, D., Langoth, N., Hoffer, M.H., Wirth, M. and Bernkop-Schnürch, A. (2004). Comparative evaluation of cytotoxicity of a glucosamine-TBA conjugate and a chitosan-TBA conjugate Int. J. Pharm., 278, 353-360.
  262. Guggi, D., Marschütz, M.K., and Bernkop-Schnürch, A. (2004). Matrix tablets based on thiolated poly(acrylic acid): pH-dependent variation in disintegration and mucoadhesion. Int. J. Pharm., 274, 97-105.
  263. Krauland, A. and Bernkop-Schnürch, A. (2004). Thiomers: Development and in vitro evaluation of a peroral microparticulate peptide delivery system. Eur. J. Pharm. Biopharm., 57, 181-187.
  264. Krauland, A., Guggi, D. and Bernkop-Schnürch, A. (2004). Oral insulin delivery: The potential of thiolated chitosan-insulin tablets on non-diabetic rats. J. Control. Rel., 95, 547-555.
  265. Leitner, V., Guggi, D. and Bernkop-Schnürch, A. (2004). Thiomers in noninvasive polypeptide delivery: In vitro and in vivo characterization of a polycarbophil-cysteine/glutathione gel formulation for human growth hormone J. Pharm. Sci., 93, 1682-1691.
  266. Leitner, V.M. and Bernkop-Schnürch, A. (2004). Polymer-enzyme inhibitor conjugates: influence of the molecular mass on the inhibition of membrane-bound aminopeptidase N activity J. Drug Del. Sci.Tech., 14, 495-498.
  267. Leitner, V.M., Guggi, D., Krauland, A.H. and Bernkop-Schnürch, A. (2004). Nasal delivery of human growth hormone: in vitro and in vivo evaluation of a thiomer/glutathione microparticulate delivery system. J. Control. Rel., 100, 87-95.
  268. Roldo, M., Hornof, M., Caliceti, P. and Bernkop-Schnürch, A. (2004). Mucoadhesive thiolated chitosans as platforms for oral controlled drug delivery: Synthesis and in vitro evaluation. Eur. J. Pharm. Biopharm., 57, 115-121.
  269. Bernkop-Schnürch, A., Egger, C. Elhassan, I.M. and Krauland, A. (2003). Preparation and in vitro characterization of poly(acrylic acid)-cysteine mircoparticles. J. Control. Rel., 93, 29-38.
  270. Bernkop-Schnürch, A., Hornof, M. and Zoidl, T. (2003). Thiolated polymers – thiomers: modification of chitosan with 2-iminothiolane. Int. J. Pharm., 260, 229-237.
  271. Bernkop-Schnürch, A., Telsnig. J. and Hornof, M. (2003). Development and in vitro evaluation of a mucoadhesive oral delivery system for antisense oligonucleotides. Sci. Pharm., 71, 165-177.
  272. Guggi, D. and Bernkop-Schnürch, A. (2003). In vitro evaluation of polymeric excipients protecting calcitonin against degradation by intestinal serine proteases. Int. J. Pharm., 252, 187-196.
  273. Guggi, D., Kast, C.E., and Bernkop-Schnürch, A. (2003). In vivo evaluation of an oral salmon calcitonin-delivery system based on a thiolated chitosan carrier matrix. Pharm. Res., 20, 1989-1994.
  274. Guggi, D., Krauland, A.H., and Bernkop-Schnürch, A. (2003). Systemic peptide delivery via the stomach: in vivo evaluation of an oral dosage form for salmon calcitonin. J. Control. Rel., 92, 125-135.
  275. Hornof, M.D., Kast, C.E., and Bernkop-Schnürch, A. (2003). In vitro evaluation of the viscoelastic properties of chitosan - thioglycolic acid conjugates. Eur. J. Pharm. Biopharm., 55, 185-190.
  276. Hornof, M.D., Weyenberg, W., Ludwig, A., and Bernkop–Schnürch, A. (2003). A mucoadhesive ocular insert: Development and in vivo evaluation in humans. J. Control. Rel., 89, 419-428.
  277. Imam, M.E., Hornof, M., Valenta, C., and Bernkop-Schnürch, A. (2003). Evidence for the interpenetration of mucoadhesive polymers into the mucus gel layer. STP Pharma Sci., 13, 171-176.
  278. Kast, C.E., Frick, W., Losert, U. and Bernkop-Schnürch, A. (2003). Chitosan-thioglycolic acid conjugate: A new scaffold material for tissue engineering? Int. J. Pharm., 256, 183-189.
  279. Kast, C.E., Guggi, D., Langoth, N. and Bernkop-Schnürch, A. (2003). Development and in vivo evaluation of an oral delivery system for low molecular weight heparin based on thiolated polycarbophil. Pharm. Res., 20, 931-936.
  280. Krauland, A., Leitner, V. M. and Bernkop-Schnürch, A. (2003). Improvement in the in situ gelling properties of deacetylated gellan gum by the immobilization of thiol groups. J. Pharm. Sci., 92, 1234-1241.
  281. Langoth, N., Kalbe, J. and Bernkop-Schnürch, A. (2003). Development of buccal drug delivery systems based on a thiolated polymer. Int. J. Pharm., 252, 141-148.
  282. Leitner, V., Marschütz, M., and Bernkop-Schnürch, A. (2003). Mucoadhesive and cohesive properties of poly(acrylic acid)-cysteine conjugates with regard to their molecular mass. Eur. J. Pharm. Sci., 18, 89-96.
  283. Leitner, V., Walker, G.F., and Bernkop-Schnürch, A. (2003). Thiolated polymers: Evidence for the formation of disulphide bonds with mucus glycoproteins. Eur. J. Pharm. Biopharm., 56, 207-214.
  284. Bernkop-Schnürch, A., Hornof, M.D., Kast, C.E. and Langoth N. (2002). Thiolated polymers: Stability of thiol moieties under different storage conditions. Sci. Pharm., 70, 331-339.
  285. Clausen, A.E., Kast, C.E. and Bernkop-Schnürch, A. (2002). The role of glutathione in the permeation enhancing effect of thiolated polymers. Pharm. Res., 19, 602-608.
  286. Hornof, M.D. and Bernkop-Schnürch, A. (2002). In vitro evaluation of the permeation enhancing effect of polycarbophil - cysteine conjugates on the cornea of rabbits. J. Pharm. Sci., 91, 2588-2592.
  287. Kast, C.E. and Bernkop-Schnürch, A. (2002). Influence of the molecular mass on the permeation enhancing effect of different poly(acrylates). STP Pharma Sci., 12, 351-356.
  288. Kast, C.E., and Bernkop-Schnürch, A. (2002). Polymer-cystamine conjugates: New mucoadhesive excipients for drug delivery? Int. J. Pharm., 234, 91-99.
  289. Kast, C.E., Valenta, C., Leopold, M. and Bernkop-Schnürch, A. (2002). Design and in vitro evaluation of a novel bioadhesive vaginal drug delivery system for clotrimazole. J. Control. Rel., 81, 347-354.
  290. Marschütz, M.K., and Bernkop-Schnürch, A. (2002). Thiolated polymers: Advance in mucoadhesion by use of in-situ crosslinking poly(acrylic acid)-cysteine conjugates. Eur. J. Pharm. Sci., 15, 387-394.
  291. Marschütz, M.K., Zauner, W., Mattner, F., Otava, A., Buschle, M. and Bernkop-Schnürch, A. (2002). Improvement of the enzymatic stability of a cytotoxic T-lymphocyte epitope model peptide for its oral administration. Peptides, 23, 1727-1733.
  292. Valenta, C., Marschütz, M., Egyed, Ch., and Bernkop-Schnürch, A. (2002). Evaluation of the inhibitory effect of thiolated poly(acrylates) on vaginal membrane bound aminopeptidase N. J. Pharm. Pharmacol., 54, 603-610.
  293. Walker, G.F., Langoth, N., and Bernkop-Schnürch, A. (2002). Peptidase activity on the surface of the porcine buccal mucosa. Int. J. Pharm., 233, 141-147.
  294. Bernkop-Schnürch, A. and Hopf, Th.E. (2001). Synthesis and In vitro evaluation of chitosan-thioglycolic acid conjugates. Sci. Pharm., 69, 109-118.
  295. Bernkop-Schnürch, A., Clausen, A.E., and Hnatyszyn, M. (2001). Thiolated polymers: Synthesis and in vitro evaluation of polymer-cysteamine conjugates. Int. J. Pharm., 226, 185-194.
  296. Bernkop-Schnürch, A., Kast, C.E., and Richter, M.F. (2001). Improvement in the mucoadhesive properties of alginate by the covalent attachment of cysteine. J. Control. Rel., 71, 277-285.
  297. Bernkop-Schnürch, A., Zarti, H., and Walker, G.F. (2001). Thiolation of polycarbophil enhances its inhibition of soluble and intestinal brush border membrane bound aminopeptidase N. J. Pharm. Sci., 90, 1907-1914.
  298. Clausen, A.E., and Bernkop-Schnürch, A. (2001). Direct compressible polymethacrylic acid-starch compositions for site specific drug delivery. J. Control. Rel., 75, 93-102.
  299. Clausen, A.E., and Bernkop-Schnürch, A. (2001). Thiolated carboxymethylcellulose: In vitro evaluation of its permeation enhancing effect on peptide drugs. Eur. J. Pharm. Biopharm., 51, 25-32.
  300. Clausen, A.E., and Bernkop-Schnürch, A. (2001). in vitro evaluation of matrix tablets based on tiolated polycarbophil. Pharm. Ind., 63, 312-317.
  301. Kast, C.E., and Bernkop-Schnürch, A. (2001). Thiolated polymers: Development and in vitro evaluation of chitosan-thioglycolic acid conjugates. Biomaterials, 22, 2345 - 2352.
  302. Marschütz, M.K., Puttipipatkhachorn, S., and Bernkop-Schnürch, A. (2001). Design and in vitro evaluation of a mucoadhesive oral delivery system for a model (poly)peptide antigen. Pharmazie, 56, 724-729.
  303. Marschütz, M.K., Veronese, F.M., and Bernkop-Schnürch, A. (2001). Influence of the spacer on the inhibitory effect of different polycarbophil-protease inhibitor conjugates. Eur. J. Pharm. Biopharm., 52, 137-144.
  304. Valenta, C., Kast, E.C., Harich, I., and Bernkop-Schnürch, A. (2001). Development and in vitro evaluation of a mucoadhesive vaginal delivery system for progesterone. J. Control. Rel., 77, 323-332.
  305. Valenta, C., Walzer, A., Clausen, A.E., and Bernkop-Schnürch, A. (2001). Thiolated polymers: Development and evaluation of transdermal delivery systems for progesterone. Pharm. Res., 18, 211-216.
  306. Bernkop-Schnürch, A. and Gilge, B. (2000). Anionic mucoadhesive polymers as auxiliary agents for the peroral administration of (poly)peptide drugs: influence of the gastric fluid. Drug Dev. Ind. Pharm., 26, 107-113.
  307. Bernkop-Schnürch, A. and Steininger, S. (2000). Synthesis and characterisation of mucoadhesive thiolated polymers. Int. J. Pharm., 194, 239-247.
  308. Bernkop-Schnürch, A. and Thaler, S. (2000). Polycarbophil-cysteine conjugates as platforms for oral (poly)peptide delivery systems. J. Pharm. Sci., 89, 901-909.
  309. Bernkop-Schnürch, A., Giovanelli, R., and Valenta, C. (2000). Peroral administration of enzymes: Strategies to improve the galenic of dosage forms for trypsin and bromelain. Drug Dev. Ind. Pharm., 26, 115-121.
  310. Bernkop-Schnürch, A., Scholler, S., and Biebel, R.G. (2000). Development of controlled drug release systems based on polymer-cysteine conjugates. J. Control. Rel., 66, 39-48.
  311. Clausen, A.E., and Bernkop-Schnürch, A. (2000). In vitro evaluation of the permeation-enhancing effect of thiolated polycarbophil. J. Pharm. Sci., 89, 1253-1261.
  312. Kratzel, M. and Bernkop-Schnürch, A. (2000). Valaminols, probably the most simplified peptide-analogs acting as pepsin inhibitors. Peptides, 21, 289-293.
  313. Marschütz, M.K. and Bernkop-Schnürch, A. (2000). Oral peptide drug delivery: Polymer-inhibitor conjugates protecting insulin from enzymatic degradation. Biomaterials, 21, 1499-1507.
  314. Marschütz, M.K., Caliceti, P., and Bernkop-Schnürch, A. (2000). Design and in vivo evaluation of an oral delivery system for insulin. Pharm. Res., 17, 1468-1474.
  315. Bernkop-Schnürch, A. and Freudl, J. (1999). Comparative in vitro study of different chitosan-complexing agent conjugates. Pharmazie, 54, 369-371.
  316. Bernkop-Schnürch, A., Brandt U.-M., and Clausen, A. (1999). Synthese und in Vitro Evaluierung von Chitosan-Cystein Konjugaten. Sci. Pharm., 67, 197-208.
  317. Bernkop-Schnürch, A., Kirchmayer, R. and Kratzel, M. (1999). Synthesis, development and in vitro evaluation of drug delivery systems with protective effect towards pepsinic degradation. J. Drug Targ., 7, 55-63.
  318. Bernkop-Schnürch, A., Schwarz, V., and Steininger, S. (1999). Polymers with thiol groups: A new generation of mucoadhesive polymers? Pharm. Res., 16, 876-881.
  319. Bernkop-Schnürch, A., Valenta, C., and Daee, S.M. (1999). Peroral polypeptide delivery: A comparative in vitro study of mucolytic agents. Arzneimittelforschung., 49, 799-803.
  320. Kratzel, M., Hiessböck, R., and Bernkop-Schnürch, A. (1999). Auxiliary agents for the peroral administration of peptide and protein drugs: Synthesis and evaluation of novel pepstatin analogues. J. Med. Chem., 41, 2339-2344.
  321. Valenta, C., Nowack, E., and Bernkop-Schnürch, A. (1999). Deoxycholate-hydrogels: Novel drug carrier systems for topical use. Int. J. Pharm., 185, 103-111.
  322. Bernkop-Schnürch, A., and Krajicek, M.E. (1998). Mucoadhesive polymers as platforms for peroral peptide delivery and absortion: Synthesis and evaluation of different chitosan-EDTA conjugates. J. Control. Rel., 50, 215-223.
  323. Bernkop-Schnürch, A., and Pasta, M. (1998). Intestinal peptide and protein delivery: Novel bioadhesive drug carrier matrix shielding from enzymatic attack. J. Pharm. Sci., 87, 430-434.
  324. Bernkop-Schnürch, A., and Scerbe-Saiko, A. (1998). Synthesis and in vitro evaluation of chitosan-EDTA-protease-inhibitor conjugates which might be useful in oral delivery of peptides and proteins. Pharm. Res., 15, 263-269.
  325. Bernkop-Schnürch, A., Humenberger, C., and Valenta, C. (1998). Basic studies on bioadhesive delivery systems for peptide and protein drugs. Int. J. Pharm., 165, 217-225.
  326. Bernkop-Schnürch, A., Krauland, A., and Valenta, C. (1998). Development and in vitro evaluation of a drug delivery system based on chitosan-EDTA BBI conjugate. J. Drug Targ., 6, 207-214.
  327. Bernkop-Schnürch, A., Krist, S., Vehabovic, M., and Valenta, C. (1998). Synthesis and evaluation of lysozyme derivatives exhibiting an enhanced antimicrobial action. Eur. J. Pharm. Sci., 6, 301-306.
  328. Kratzel, M., Schlichtner, B., Kirchmayer, R. and Bernkop-Schnürch, A. (1998). Simplified pepstatins: Synthesis and evaluation of N-terminally modified analogues. J. Med. Chem., 42, 2041-2045.
  329. Valenta., C., Christen, B., and Bernkop-Schnürch, A. (1998). Chitosan-EDTA conjugate: A novel polymer for topical used gels. J. Pharm. Pharmacol., 50, 445-452.
  330. Valenta., C., Schwarz, E.G., and Bernkop-Schnürch, A. (1998). Lysozyme caffeic acid conjugates: possible novel preservatives for dermatics. Int. J. Pharm., 174, 125-132.
  331. Bernkop-Schnürch, A., and Apprich, I. (1997). Synthesis and evaluation of a modified mucoadhesive polymer protecting from alpha-chymotrypsinic degradation. Int. J. Pharm., 146, 247-254.
  332. Bernkop-Schnürch, A., and Göckel, N.C. (1997). Development and analysis of a polymer protecting from luminal enzymatic degradation caused by alpha-chymotrypsin. Drug Dev. Ind. Pharm., 23, 733-740.
  333. Bernkop-Schnürch, A., and Marschütz, M. (1997). Development and in vitro evaluation of systems to protect peptide drugs from aminopeptidase N. Pharm. Res., 14, 181-185.
  334. Bernkop-Schnürch, A., Bratengeyer, I., and Valenta, C. (1997). Development and in vitro evaluation of a drug delivery system protecting from trypsinic degradation. Int. J. Pharm., 157, 17-25.
  335. Bernkop-Schnürch, A., Gabor, F., and Spiegl, P. (1997). Bacterial adhesins as a drug carrier: covalent attachment of K99 fimbriae to 6-methylprednisolone. Pharmazie, 52, 41-44.
  336. Bernkop-Schnürch, A., Paikl, Ch., and Valenta, C. (1997). Novel bioadhesive chitosan-EDTA conjugate protects leucine enkephalin from degradation by aminopeptidase N. Pharm. Res., 14, 917-922.
  337. Bernkop-Schnürch, A., Schwarz, G.H., and Kratzel M. (1997). Modified mucoadhesive polymers for the peroral administration of mainly elastase degradable therapeutic (poly)peptides. J. Control. Rel., 47, 113-121.
  338. Gabor, F., Bernkop-Schnürch, A., and Hamilton, G. (1997). Bioadhesion to the intestine by means of E. coli K99-fimbriae: Gastrointestinal stability and specificity of adherence. Eur. J. Pharm. Sci., 5, 233-242.
  339. Valenta, C., Bernkop-Schnürch, A. and Schwartz, M. (1997). Modification of lysozyme with cinnamaldehyde: A strategy for constructing novel biopreservatives for dermatics. Int. J. Pharm., 148, 131-137.
  340. Bernkop-Schnürch, A. and Fragner, R. (1996). Investigations into the diffusion behaviour of polypeptides in native intestinal mucus with regard to their peroral administration. Pharm. Sciences, 2, 361-363.
  341. Bernkop-Schnürch, A., and Dundalek, K. (1996). Novel bioadhesive drug delivery system protecting (poly)peptides from gastric enzymatic degradation. Int. J. Pharm., 138, 75-83.
  342. Bernkop-Schnürch, A., Valenta, C., and Gatterwe, V. (1996). In vitro skin permeation studies of the lantibiotic nisin. Eur. J. Pharm. Biopharm., 42, 336-339.
  343. Valenta, C., Bernkop-Schnürch, A., and Rigler, H.P. (1996). The anti-staphylococcal effect of nisin in a suitable vehicle, a potential therapy for atopic dermatitis. J. Pharm. Pharmacol., 48, 988-991.
  344. Valenta, C., Bernkop-Schnürch, A., and Teltscher, C. (1996). Nisin, ein potentielles Konservierungsmittel in topischen Zubereitungen. Pharmazie, 51, 119-122.
  345. Bernkop-Schnürch, A., and Valenta, C. (1995). Untersuchungen zur mikrobiellen Stabilität von magistral hergestellten hydrophilen Cremes und Gelen. ÖAZ, 49, 926-929.
  346. Bernkop-Schnürch, A., Gabor, F., Szostak, M.P., and Lubitz, W. (1995). Production of adhesive drug carriers using recombinant DNA-technology. Sci. Pharm., 63, 159-166.
  347. Bernkop-Schnürch, A., Gabor, F., Szostak, M.P., and Lubitz, W. (1995). An adhesive drug delivery system based on K99-fimbriae. Eur. J. Pharm. Sci., 3, 293-299.
  348. Bernkop-Schnürch, A., Valenta, C. and Urban, U. (1995). Microbiological stability of iIndividually prepared dermatica. Sci. Pharm., 63, 65-70.
  349. Valenta, C., and Bernkop-Schnürch, A. (1993). Untersuchungen von Kontaminationsrisken bei der Herstellung von magistralen Augentropfen. ÖAZ, 47, 141-143.
  350. Kopp, B., Bauer, W.P., and Bernkop-Schnürch, A. (1992). Analysis of some Malaysian dart poisons. J. Ethnopharmacol., 36, 57-62.

Reviews:

  1. 1. Zupančič, O.; Bernkop-Schnürch, A. (2017). Lipophilic peptide character - What oral barriers fear the most. J. Control. Rel., 255, 242-257.
  2. Partenhauser, A.; Bernkop-Schnürch, A. (2016). Mucoadhesive polymers in the treatment of dry X syndrome. Drug Discovery Today, 21, 1051-1062.
  3. Netsomboon, K.; Bernkop-Schnürch, A. (2016). Mucoadhesive vs. mucopenetrating particulate drug delivery. Eur. J. Pharm. Biopharm., 98, 76-89.
  4. Grießinger, J.; Dünnhaupt, S.; Cattoz, B.; Griffiths, P.; Oh, S.; Gómez, S.B.; Wilcox, M.; Pearson, J.; Gumbleton, M.; Abdulkarim, M.; Pereira de Sousa, I.; Bernkop-Schnürch, A. (2015). Methods to determine the interactions of micro- and nanoparticles with mucus. Eur. J. Pharm. Biopharm., 96, 464-476.
  5. Ijaz, M.; Bernkop-Schnürch, A. (2015). Preactivated thiomers: their role in drug delivery. Expert Opin. Drug Deliv., 12, 1269-1281.
  6. Dünnhaupt, S.; Kammona, O.; Waldner, C.; Kiparissides, C.; Bernkop-Schnürch, A. (2015). Nano-carrier systems: Strategies to overcome the mucus gel barrier. Eur. J. Pharm. Biopharm., 96, 447-453.
  7. Bernkop-Schnürch, A. (2013). Reprint of: Nanocarrier systems for oral drug delivery: do we really need them? Eur. J. Pharm. Sci., 50, 2-7.
  8. Laffleur, F.; Bernkop-Schnürch, A. (2013). Strategies for improving mucosal drug delivery. Nanomedicine, 8, 2061-2075.
  9. Bernkop-Schnürch, A. (2013). Nanocarrier systems for oral drug delivery: Do we really need them? Eur. J. Pharm. Sci., 49, 272-277.
  10. Bernkop-Schnürch, A.; Dünnhaupt, S. (2012). Chitosan based drug delivery systems. Eur. J. Pharm. Biopharm., 81, 463-469.
  11. Hoyer, H.; Perera, G.; Bernkop-Schnürch, A. (2010). Noninvasive delivery systems for peptides and proteins in osteoporosis therapy: a retroperspective. Drug Dev. Ind. Pharm., 36, 31-44.
  12. Sakloetsakun, D.; Bernkop-Schnürch, A. (2010). Thiolated Chitosans. J. Drug Del. Sci.Tech., 20, 63-69.
  13. Baloglu, E.; Senyigit, Z.A.; Karavana, S.Y.; Bernkop-Schnürch, A. (2009). Strategies to prolong the intravaginal residence time of drug delivery systems. J. Pharm.Pharmaceut.Sci., 12, 312-336
  14. Werle, M.; Bernkop-Schnürch, A. (2008). Thiolated chitosans: useful excipients for oral drug delivery. J. Pharm. Pharmacol., 60, 273-281.
  15. Albrecht, K. and Bernkop-Schnürch, A. (2007). Thiomers: forms, functions and applications to nanomedicine. Nanomedicine, 2, 41-50.
  16. Bernkop-Schnürch, A. and Grabovac V. (2006). Polymeric efflux pump inhibitors in oral drug delivery. Am. J. Drug. Deliv., 4, 263-272.
  17. Bernkop-Schnürch, A. (2005). Mucoadhesive systems in oral drug delivery. Drug Discovery Today: Technologies, 2, 83-87.
  18. Bernkop-Schnürch, A. (2005). Thiomers: A new generation of mucoadhesive polymers. Adv. Drug Del. Rev., 57, 1569-1582.
  19. Bernkop-Schnürch, A. and Greimel, A. (2005). Thiomers: The next generation of mucoadhesive polymers. Am. J. Drug. Deliv., 3, 141-154.
  20. Langoth, N. and Bernkop-Schnürch, A. (2005). The use of multifunctional polymers as auxiliary agents in non-invasive peptide delivery. Am. Pharm. Rev., 8, 80-84.
  21. Bernkop-Schnürch, A., Krauland, A.H., Leitner, V.M. and Palmberger, Th. (2004). Thiomers: potential excipients for non-invasive peptide delivery systems. Eur. J. Pharm. Biopharm., 58, 253-263.
  22. Bernkop-Schnürch, A., Hoffer, M. and Kafedjiiski, K. (2004). Thiomers for oral delivery of hydrophilic macromolecular drugs. Expert Opin. Drug Deliv., 1, 87-98.
  23. Bernkop-Schnürch, A., Clausen ,A.E. and Guggi, D. (2004). The use of auxiliary agents to improve the mucosal uptake of peptides. Med. Chem. Rev., 1, 1-10.
  24. Bernkop-Schnürch, A., Hornof, M.D. and Guggi, D. (2004). Thiolated chitosans. Eur. J. Pharm. Biopharm., 57, 9-17.
  25. Bernkop-Schnürch, A. Kast, C.E. and Guggi, D. (2003). Permeation enhancing polymers in oral delivery of hydrophilic macromolecules: Thiomer / GSH systems. J. Control. Rel., 93, 95-103.
  26. Bernkop-Schnürch, A. and Hornof, M.D. (2003). Intravaginal delivery: Design, challenges and solutions. Am. J. Drug. Deliv., 1, 241-254.
  27. Bernkop-Schnürch, A. and Clausen A.E. (2002). Membranes as targets for drug design: Biomembrane permeability of peptides: Strategies to improve their mucosal uptake. Mini Rev. Med. Chem., 2, 295-305.
  28. Bernkop-Schnürch, A. and Walker, G. (2001). Multifunctional matrices for oral peptide delivery. Crit. Rev. Ther. Drug Carr. Syst., 18, 459-501.
  29. Bernkop-Schnürch, A. and Kast, C. (2001). Chemically modified chitosans as enzyme inhibitors. Adv. Drug Del. Rev., 52, 127-137.
  30. Bernkop-Schnürch, A. (2000). The use of multifunctional polymers for the noninvasive peptide and protein application. Expert Opin. Ther. Pat. 10, 1357-1366.
  31. Bernkop-Schnürch, A. (2000). Chitosan and its derivatives: Potential excipients for peroral peptide delivery systems. Int. J. Pharm., 194, 1-13.
  32. Bernkop-Schnürch, A. (1999). Polymer-inhibitor conjugates: A promising strategy to overcome the enzymatic barrier to perorally administered (poly)peptide drugs? STP Pharma Sci., 9, 83-92.
  33. Bernkop-Schnürch, A. (1998). The use of inhibitory agents to overcome the enzymatic barrier to perorally administered therapeutic peptides and proteins. J. Control. Rel., 52, 1-16.
  34. Bernkop-Schnürch, A. (1997). Strategien zur peroralen Applikation von Peptid- und Proteinwirkstoffen. Sci. Pharm., 65, 61-81.
  35. Bernkop-Schnürch, A. (1997). Bioadhäsive Polymere als Hilfsstoffe zur peroralen Applikation von Peptid- und Proteinwirkstoffen. ÖAZ, 51, 490-495.

 

Book contributions:

  1. Müller, C.; Bernkop-Schnürch, A. (2014). Chapter 11: Thiomers. Buchbeitrag: Mucoadhesive Materials and Drug Delivery Systems. John Wiley & Sons Ltd.
  2. Bernkop-Schnürch, A. (2013). Mucoadhesive polymers: Basics, Strategies and Future Trends. Buchbeitrag: Polymeric Biomaterials. 3rd edition (Ed. Severian Dumitriu) Marcel Dekker, New York 193-220.
  3. Perera, G.; Bernkop-Schnürch, A. (2012). Pharmaceutical Non-Viral Formulations for Gene Vaccines. Buchbeitrag: Gene Vaccines Ed. Thalhammer Josef. 109-125.
  4. Hombach, J.; Bernkop-Schnürch, A. (2010). Mucoadhesive drug delivery systems. Buchbeitrag: Handbook of Experimental Pharmacology Ed Monika Schäfer-Korting Springer Heidelberg. 202-220
  5. Bernkop-Schnürch, A. (2009). Oral Delivery of Macromolecular Drugs: Barriers, Strategies and Future Trends. Buch Herausgeberschaft
  6. Bernkop-Schnürch, A. (2009). Low molecular mass permeation enhancers in oral delivery of molecular drugs. Buchbeitrag: Oral Delivery of Macromolecular Drugs: Barriers, Strategies and Future Trends. 85-101.
  7. Vetter, A.; Bernkop-Schnürch, A. (2009). Bioadhesive Delivery Systems. Buchbeitrag: Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development, 218-234.
  8. Bernkop-Schnürch, A. (2008). Thiolated chitosans in non-invasive drug delivery. Buchbeitrag: Natural-based polymers for biomedical applications. 624-643.
  9. Werle, M. and Bernkop-Schnürch, A. (2007). Inhibition of enzymes and secretory transport. Buchbeitrag: Enhancement in drug delivery Elka Touitou and Brian W. Barry CRC Press 85-109.
  10. Bernkop-Schnürch, A. (2002). Mucoadhesive polymers. Buchbeitrag: Polymeric Biomaterials. 2nd edition (Ed. Severian Dumitriu) Marcel Dekker, New York. 147-165.




*author for correspondence