Publications
An inhibitor-mediated beta-cell dedifferentiation model reveals distinct roles for FoxO1 in glucagon repression and insulin maturation
Casteels T, Zhang Y, Frogne T, Sturtzel C, Lardeau CH, Sen I, Liu X, Hong S, Pauler FM, Penz T, Brandstetter M, Barbieux C, Berishvili E, Heuser T, Bock C, Riedel CG, Meyer D, Distel M, Hecksher-Sørensen J, Li J, Kubicek S.
Mol Metab. 2021 Aug 25:101329. DOI: 10.1016/j.molmet.2021.101329. Epub ahead of print.
Generation of an hiPSC-1 knock-in line expressing TY1-tagged MNX1-protein together with mScarlet
Temocin O, Regele D, Sathianathan M, Überbacher C, Hartl M, Edenhofer F, Meyer D.
Stem Cell Res. 2021 Sep 2;56:102522. DOI: 10.1016/j.scr.2021.102522. Epub ahead of print.
Inducible Mosaic Cell Labeling Provides Insights Into Pancreatic Islet Morphogenesis
Freudenblum J, Meyer D and Kimmel RA (2020)
Cell Dev. Biol. 8:586651. DOI: 10.3389/fcell.2020.586651
Shock waves promote spinal cord repair via TLR3
Gollmann-Tepeköylü C, Nägele F, Graber M, et al.
Hedgehog and Gpr161: Regulating cAMP Signaling in the Primary Cilium
Tschaikner P, Enzler F, Torres-Quesada O, Aanstad P, Stefan E.
Cells 2020 Jan 3;9(1). pii: E118. doi: 10.3390/cells9010118. Pubmed
FoxH1 represses miR-430 during early embryonic development of zebrafish via non-canonical Regulation
Fischer P, Chen H, Pacho F, Rieder D, Kimmel RA, Meyer D.
Beta-cell excitability and excitability-driven diabetes in adult Zebrafish islets
Emfinger CH, Lőrincz R, Wang Y, York NW, Singareddy SS, Ikle JM, Tryon RC, McClenaghan C, Shyr ZA, Huang Y, Reissaus CA, Meyer D, Piston DW, Hyrc K, Remedi MS, Nichols CG.
In vivo monitoring of intracellular Ca2+ dynamics in the pancreatic β-cells of zebrafish Embryos
Lorincz R, Emfinger CH, Walcher A, Giolai M, Krautgasser C, Remedi MS, Nichols CG, Meyer D.
In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis
Freudenblum J, Iglesias JA, Hermann M, Walsen T, Wilfinger A, Meyer D, Kimmel RA.
Tcf7l2 plays pleiotropic roles in the control of glucose homeostasis, pancreas morphology, vascularization and Regeneration
Facchinello, N; Tarifeño-Saldivia, E; Grisan, E; Schiavone, M; Peron, M; Mongera, A; Ek, O; Schmitner, N; Meyer, D; Peers, B; Tiso, N; Argenton, F; (2017)
Ptf1a+, ela3l− cells are developmentally maintained progenitors for exocrine regeneration following extreme loss of acinar cells in zebrafish larvae
Artemisinins Target GABAA Receptor Signaling and Impair α Cell Identity
Li, J; Casteels, T; Frogne,T; Ingvorsen, C; Honoré, C; Courtney, M; et. al (2017)
Pronephric tubule morphogenesis in zebrafish depends on Mnx mediated repression of irx1b within the intermediate mesoderm
Ott, Elisabeth; Wendik, Björn; Srivastava, Monika; Pacho, Frederic; Töchterle, Sonja; Salvenmoser, Willibald; Meyer, Dirk (2016)
Partial dedifferentiation of murine radial glia type neural stem cells by Brn2 and c-Myc yields early neuroepithelial progenitors
Bung, Raffaela; Wörsdörfer, Philipp; Thier, Marc Christian; Vogt, Kathrin; Gebhardt, Martina; Edenhofer, Frank (2016)
Zebrafish Pancreas as a Model for Development and Disease
Kimmel, R.A.; Meyer, D. (2016)
In-vivo detection of binary PKA network interactions upon activation of endogenous GPCRs
Röck, R; Bachmann, V; Bhang, HC; Malleshaiah, M; Raffeiner, P; Mayrhofer, JE; Tschaikner, PM; Bister, K; Aanstad, P; Pomper, MG; Michnick, SW; Stefan, E (2015)
Scientific Reports 5, Art. No. 11133. (DOI) Pubmed
Scientific Reports 5, Art. No. 11133. (DOI) Pubmed
Hybrid ultrahigh resolution optical coherence / photoacoustic microscopy
Hermann, B.; Liu, M.; Schmitner, N.; Maurer, B.; Meyer, D.; Weninger, W. J.; Drexler, W. (2015)
Proceedings of the Society of Photo-optical Instrumentation Engineers (SPIE) 9323, No. 93232N. (DOI) (Weblink)
Partial dedifferentiation of murine radial glia type neural stem cells by Brn2 and c-Myc yields early neuroepithelial progenitors
Bung, R.; Wörsdörfer, P.; Thier, M.C.; Vogt, K.; Gebhardt, M.; Edenhofer, F. (2015)
A GFP-Tagged Gross Deletion on Chromosome 1 Causes Malignant Peripheral Nerve Sheath Tumors and Carcinomas in Zebrafish
Astone M., Pizzi M., Peron M., Domenichini A., Guzzardo V., Töchterle S., Tiso N., Rugge M., Meyer D., Argenton F.,
Vettori A. (2015)
Nmnat1-Rbp7 Is a Conserved Fusion-Protein That Combines NAD+ Catalysis of Nmnat1 with Subcellular Localization of Rbp7
Chen H., Babino D., Schoenbichler SA., Arkhipova V., Töchterle S., Martin F., Huck CW., von Lintig J., Meyer D.(2015)
Diabetic pdx1-mutant zebrafish show conserved responses to nutrient overload and anti-glycemic Treatment
Kimmel, R.A., Dobler, S., Schmitner, N., Walsen, T., Freudenblum, J., and Meyer, D. (2015)
Sci. Rep. 5, 14241 Pubmed
A Smad3 transgenic reporter reveals TGF-beta control of zebrafish spinal cord development
Casari A, Schiavone M, Facchinello N, Vettori A, Meyer D, Tiso N, Moro E, Argenton F. (2014)
Dev Biol. 2014 Oct 5 Pubmed
In vivo three dimensional dual wavelength photoacoustic tomography imaging of the far red fluorescent protein E2-Crimson expressed in adult zebrafish
Liu, M., Schmitner, N., Sandrian, M.G., Zabihian, B., Hermann, B., Salvenmoser, W., Meyer, D., Drexler, W., (2013)
Biomedical Optics Express, Vol. 4, Issue 10, pp. 1846-1855. doi: 10.1364/BOE.4.001846. OpticsInfoBase
Simultaneous three-dimensional photoacoustic and laser-ultrasound tomography
Wurzinger G., Nuster R., Schmitner N., Gratt S., Meyer D., Paltauf G. (2013)
Biomedical Optics Express. 2013 Jul 19;4(8):1380-9. doi: 10.1364/BOE.4.001380. Pubmed
High-speed panoramic light-sheet microscopy reveals global endodermal cell Dynamics
Schmid B, Shah G, Scherf N, Weber M, Thierbach K, Campos CP, Roeder I, Aanstad P, Huisken J. (2013)
Nat Commun. 2013 Jul 24;4:2207. Doi: 10.1038/ncomms3207.Pubmed
Hybrid photoacoustic and ultrasound section imaging with optical ultrasound detection
Nuster R, Schmitner N, Wurzinger G, Gratt S, Salvenmoser W, Meyer D, Paltauf G. (2013)
Cell type and tissue specific function of islet genes in zebrafish pancreas development
Wilfinger, A., Arkhipova, V., Meyer D.
Dev. Biol. (2013) Volume 378, Issue 1, 1 June 2013, Pages 25–37. doi: 10.1016/j.ydbio.2013.03.009. Pubmed
Collective mesendoderm migration relies on an intrinsic directionality signal transmitted through cell contacts
Dumortier, JG, Martin, S., Meyer, D., Rosa, FM, David, NB (2012)
Proceedings of the National Academy of Sciences, PNAS, 0027-8424, DOI: 10.1073/pnas.1205870109 Pubmed
Zebrafish Cxcr4a determines the proliferative response to Hedgehog signalling
Stueckemann, T., Wegleiter, T., Stefan, E., Naegele, O., Tarbashevich, K., Boeck, G., Raz, E., and Aanstad, P. (2012)
Development 139, 2711-2720, DOI: 10.1242/dev.074930 Pubmed
Characterization and regulation of the hb9/mnx1 beta-cell progenitor specific enhancer in zebrafish
Arkhipova V., Wendik B., Devos N., Ek O., Peers B., Meyer D. (2012)
Dev Biol. 2012 May 1;365(1):290-302. Epub 2012 Mar 9. DOI: 101016, Pubmed
Photoacoustic section imaging using an elliptical acoustic mirror and optical detection
Nuster R., Gratt S., Passler K., Meyer D., and Paltauf G.
J. Biomed. Opt. 17, 030503 (2012), DOI:10.1117/1.JBO.17.3.030503. Pubmed
Fast Homozygosity Mapping and Identification of a Zebrafish ENU-Induced Mutation by Whole-Genome Sequencing
Voz ML, Coppieters W., Manfroid I., Baudhuin A., Von Berg V., Charlier C., Meyer D., Driever W., Martial JA, Peers B. (2012)
PLoS One. 2012;7(4):e34671. Epub 2012 Apr 4. Pubmed
Requirement for Pdx1 in specification of latent endocrine progenitors in zebrafish
Kimmel RA, Onder L, Wilfinger A, Ellertsdottir E, Meyer D. (2011)
BMC Biol. 2011 Oct 31;9:75. Pubmed
Distinct expression patterns of dickkopf genes during late embryonic development of Danio rerio
Untergasser, G., Martowicz, A., Hermann, M., Töchterle, S., Meyer, D. (2011)
Gene Expr Patterns. 2011 Aug 26. Pubmed
On the Use of Frequency-Domain Reconstruction Algorithms for Photoacoustic Imagings
Schulze, R., Zangerl, G., Holotta, M., Handle, F., Meyer, D., Nuster, R., Paltauf, G., Scherzer, O.
J Biomed Opt. 2011 Aug;16(8):086002. Pubmed
Efficiency of translation termination in humans is highly dependent upon nucleotides in the neighbourhood of a (premature) termination codon
Pacho F., Zambruno G., Calabresi V., Kiritsi D., Schneider H. (2011)
J Med Genet. 2011 Sep;48(9):640-4. Pubmed
Molecular regulation of pancreas development in zebrafish
Kimmel, R., Meyer, D. (2010)
Methods Cell Biol 100, 261-80 PubMed
The Extracellular Domain of Smoothened Regulates Ciliary Localization and Is Required for High-Level Hh Signaling
Aanstad, P., Santos N., Corbit K. C., Scherz P. J. Trinh L. A., Salvenmoser W., Huisken J., Reiter J. F., Stainier D. Y. R. (2009)
Current Biology19, 1034-1039 PubMed
PlexinA3 restricts spinal exit points and branching of trunk motor nerves in embryonic zebrafish
Feldner, J., Reimer, M.M., Schweitzer, J., Wendik, B., Meyer, D., Becker, T., Becker, C.G. (2007)
Journal of Neuroscience 27/18, 4978-4983 PubMed
Nodal signaling activates differentiation genes during zebrafish gastrulation
Bennett, J.T., Joubin, K., Cheng, S., Aanstad, P., Herwig, R., Clark, M., Lehrach, H., and Schier, A.F. (2007)
Dev. Biol. 304(2), 525-540 PubMed
Expression of rasgef1b in zebrafish
Epting, D., Vorwerk, S., Hageman, A., and Meyer, D. (2007)
Gene Expr. Patterns. 7, 389-395 PubMed
Vertebrate Smoothened functions at the primary cilium
Corbit, K.C., Aanstad, P., Singla, V., Norman, A.R., Stainier, D.Y., and Reiter, J.F. (2005)
Nature. 437(7061):1018-1021 PubMed
Neuromuscular synapses can form in vivo by incorporation of initially aneural postsynaptic specializations
Flanagan-Steet, H., Fox, M.A., Meyer, D., and Sanes, J.R. (2005)
Development. 132, 4471-4481 PubMed
Expression profiling and comparative genomics identify a conserved regulatory region controlling midline expression in the zebrafish embryo
Dickmeis, T., Plessy, C., Rastegar, S., Aanstad, P., Herwig, R., Chalmel, F., Fischer, N., and Strähle, U. (2004)
Genome Res. 14(2), 228-238 PubMed
Zebrafish mnx genes in endocrine and exocrine pancreas formation
Wendik, B., Maier, E., Meyer, D. (2004)
Dev. Biol. 268, 372-83 PubMed
Evolutionary conserved role of ptf1a in the exocrine pancreatic fate
Zecchin, E. Mavropoulos, A., Devos, N.,. Filippi, A., Tiso, N., Meyer, D., Peers, B., Bortolussi, M., Argenton, F. (2004)
Prep1.1 has essential genetic functions in hindbrain development and neural crest cells differentiation
Deflorian, G., Tiso, N. , Ferretti, E. , Meyer, D. , Blasi, F. , Bortolussi, M., Argenton, F. (2004)
The Mix family homeodomain gene bonnie and clyde functions with other components of the Nodal signaling pathway to regulate neural patterning in zebrafish
Trinh, L., A., Meyer, D. and Stainier, D. Y. (2003)
Development 130, 4989-98. PubMed
An expression pattern screen for genes involved in the induction of the posterior nervous system of zebrafish
Yoda, H., Momoi, A., Esguerra, C. V., Meyer, D., Driever, W., Kondoh, H. and Furutani-Seiki, M. (2003).
Differentiation 71, 152-62. PubMed
Expression of the helix-loop-helix gene id3 in the zebrafish embryo
Dickmeis, T., Rastegar, S., Lam, C.S., Aanstad, P., Clark, M., Fischer, N., Rosa, F., Korzh, V., and Strähle, U. (2002)
Development 113(1), 99-109 PubMed
Guidance of primordial germ cell migration by the chemokine SDF-1
Doitsidou, M., Reichman-Fried, M., Stebler, J., Koprunner, M., Dorries, J., Meyer, D., Esguerra, C. V., Leung, T. and Raz, E. (2002)
Cell 111, 647-59. PubMed
Zebrafish smad7 is regulated by Smad3 and BMP signals
Pogoda H-M, Meyer D (2002)
DevDyn 224, 334-349 PubMed
Identification of nodal signaling targets by array analysis of induced complex probes
Dickmeis, T., Aanstad, P., Clark, M., Fischer, N., Herwig, R., Mourrain, P., Blader, P., Rosa, F., Lehrach, H., and Strähle, U. (2001)
DevDyn 222(4), 571-580 PubMed
A crucial component of the endoderm formation pathway, CASANOVA, is encoded by a novel sox-related gene
Dickmeis, T., Mourrain, P., Saint-Etienne, L., Fischer, N., Aanstad, P., Clark, M., Strähle, U., and Rosa, F. (2001)
Genes Dev.. 15(12), 1487-1492 PubMed
Expression of the anti-dorsalizing morphogenetic protein gene in the zebrafish embryo
Dickmeis, T., Rastegar, S., Aanstad, P., Clark, M., Fischer, N., Korzh, V., and Strähle, U. (2001)
Dev. Genes Evol.. 211(11), 568-572 PubMed
Expression of brain subtype creatine kinase in the zebrafish embryo
Dickmeis, T., Rastegar, S., Aanstad, P., Clark, M., Fischer, N., Plessy, C., Rosa, F., Korzh, V., Strähle, U. (2001)
Mech. Dev.. 109(2), 409-412 PubMed
Statistical evaluation of differential expression on cDNA nylon arrays with replicated experiments
Herwig, R., Aanstad, P., Clark, M., and Lehrach, H. (2001)
Nucleic Acids Res.. 29(23), U1-U9 PubMed
The gene schmalspur functions in mesoderm formation in zebrafish, and interacts with notail and spadetail
Rojo, C., Ellertsdottir, E., Pogoda, H. M. and Meyer, D. (2001)
Int. J. Dev. Biol. 45, 157-S158
Pou2 is required during establishment of the zebrafish midbrain-hindbrain boundary organizer
Belting HG, Hauptmann G, Meyer D, Abdelilah-Seyfried S, Chitnis A, Eschbach C, Soll I, Thisse, C, Thisse B, Artinger KB, Lunde K, Driever W (2001)
Development 128, 4165-76 PubMed
The zebrafish forkhead transcription factor FoxH1/Fast1 is a modulator of nodal signaling required for organizer formation
Pogoda H-M, Solnica-Krezel L, Driever W, Meyer D. (2000)
Curr Biol. 10, 1041-9. PubMed
Predictability of dorso-ventral asymmetry in the cleavage stage zebrafish embryo: an analysis using lithium sensitivity as a dorso-ventral marker
Aanstad, P. and Whitaker, M. (1999)
Mech. Dev.. 88(1), 33-41 PubMed
Vg1 RBP intracellular distribution and evolutionarily conserved expression suggest multiple roles during development
Zhang, Q., Yaniv, K., Oberman, F., Wolke, U., Git, A., Fromer, M., Taylor, W.L., Meyer, D., Standart, N., Raz,
E.and Joel K. Yisraeli (1999)
Mech Dev. 88, 101-106 PubMed
Genetic analysis of pattern formation in the zebrafish neural plate
Driever, W., Solnica-Krezel, L. Abdelilah, S., Meyer, D. and Stemple D. (1997)
Embryonic Pattern Formation. CSHSQR, 62, 523-34 (Review) PubMed
Isoform-specific expression and function of neuregulin
Meyer, D., Yamaai, T., Garratt, A., Riethmacher-Sonnenberg, E., Kane, D., Theill, L.E. and Birchmeier, C. (1997)
Development, 124, 3575-3586 PubMed
Multiple essential functions of neuregulin in development
Meyer, D. and Birchmeier, C. (1995)
Nature, 378, 386-390 PubMed
Sequential requirement for hepatocyte growth factor and neuregulin in the morphogenesis and differentiation of the mammary gland
Yang, Y., Spitzer, E., Meyer, D., Sachs, M., Niemann, C., Hartmann, G., Weidner, K.M., Birchmeier, C. and Birchmeier, W. (1995)
J. Cell. Biol. 131, 215-226 PubMed
Factors Controlling Growth, Motility, and Morphogenesis of Normal and Malignant Epithelial Cells
Birchmeier, C., Meyer, D. and Riethmacher, D. (1995)
Int. Rev. Cytol. 160, 221-266 (Review) PubMed
Distinct isoforms of neuregulin are expressed in mesenchymal and neuronal cells during mouse development
Meyer, D. and Birchmeier, C. (1994)
Proc. Natl. Acad. Sci. USA 91, 1064-1068 PubMed
Scatter Factor/Hepatocyte Growth Factor and its Receptor, the c-met Tyrosine Kinase, can Mediate a Signal Exchange Between Mesenchyme and Epithelia During Mouse Embryogenesis
Sonnenberg, E., Meyer, D., Weidner, M. and Birchmeier, C. (1993)
J. Cell. Biol. 123, 223-235 PubMed