IBA researchers demonstrated that proliferation and adipogenic differentiation is impaired in human white adipose-derived progenitor cells. Moreover, the research group provided evidence suggesting that adipose-derived progenitor cell senescence contributes to dysfunctions in triglyceride storage and adipokine secretion in human white adipose tissue.
Mitterberger M.C., Lechner S., Mattesich M. and Zwerschke W. Adipogenic differentiation is impaired in replicative senescent human subcutaneous adipose-derived stromal/progenitor cells. J Gerontol A Biol Sci Med Sci 2014;69:13-24.
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