IBA researchers have characterized bone-marrow T cells from the femur in old age
In an article published in Immunity&Ageing (http://www.ncbi.nlm.nih.gov/pubmed/23642143) they show that bone marrow T cells from the femur are similar to iliac crest derived cells in old age and represent a useful tool for studying the aged immune system. The approach is innovative, because until recently research on the aging human immune system was restricted to the analysis of peripheral blood cells. The concept that adaptive immune cells in the bone marrow play an important regulatory role opens a new dimension in immunogerontology. The project is the result of a collaboration with two clinical departments, the Department of Orthopedic Surgery and the Department of Cranio-Maxillofacial and Oral Surgery.
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