Sabine Gruber

Sabine Gruber, Mag. Dr. (PhD)
Scientific researcher

Institute of Microbiology
Technikerstr. 25d
A-6020 Innsbruck

Viktor-Franz-Hess Haus, 6th floor, room 06-04

Tel.: +43 (0)512 507 51257

Fax: +43 (0)512 507 2928

Mail: Sabine.Gruber@uibk.ac.at

Homepage: ChitoScience 

 

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Research Areas

  • Biopolymers: Chitin and chitosan
  • Cellwall metabolism in filamentous fungi
  • Mycoparasitism and biocontrol
  • Industrial biotechnology
  • Molecular mycology
  • Signal transduction in fungi

Projects

Other responsibilities

  • Lab organisation and management
  • Supervision of Bachelor-, Master- and PhD students

Publications

List of publications ›

Peer-reviewed articles Journal Publications

  1. Kappel L, Münsterkötter M, Sipos G, Escobar Rodriguez C, Gruber Chitin and chitosan remodeling defines vegetative development and Trichoderma biocontrol. PLoS Pathog. 2020 Feb 20;16(2):e1008320. doi: 10.1371/journal.ppat.1008320.PMID: 32078661; PMCID: PMC7053769.

  2. Lea Atanasova, Sabine Gruber, Alexander Lichius, Theresa Radebner, Leoni Abendstein, Martin Münsterkötter, Nancy Stralis-Pavese, Paweł P. Łabaj, David P. Kreil, Susanne Zeilinger: The Gpr1-regulated Sur7 family protein Sfp2 is required for hyphal growth and cell wall stability in the mycoparasite Trichoderma atroviride. Scientific Reports 12/2018; 8(1)., DOI:10.1038/s41598-018-30500-y

  3. Sabine Gruber, Susanne Zeilinger: The Transcription Factor Ste12 Mediates the Regulatory Role of the Tmk1 MAP Kinase in Mycoparasitism and Vegetative Hyphal Fusion in the Filamentous Fungus Trichoderma atroviride. PLoS ONE 10/2014; 9(10):e111636.., DOI:10.1371/journal.pone.0111636

  4. M. Vieira, S. Zeilinger, R.S. Brandão, G.R. Vianna, R.C. Georg, S. Gruber, F.J.L. Aragão, C.J. Ulhoa: Overexpression of an aquaglyceroporin gene in the fungal biocontrol agent Trichoderma harzianum affects stress tolerance, pathogen antagonism and Phaseolus vulgaris development. Biological Control 08/2018; 126., DOI:10.1016/j.biocontrol.2018.08.012

  5. Matthias Holzlechner, Sonja Reitschmidt, Sabine Gruber, Susanne Zeilinger, Martina Marchetti-Deschmann: Visualizing fungal metabolites during mycoparasitic interaction by MALDI mass spectrometry imaging. Proteomics 03/2016; 16(11-12):n/a-n/a., DOI:10.1002/pmic.201500510

  6. Zeilinger, S. Gruber, T. Radebner, A. Lichius: The Trichoderma atroviride 7-transmembrane receptor Gpr1 is essential for fungal mycoparasitism and interacts with a Sur7 family membrane protein. Mycoses 09/2015; 58:21-22.

  7. Sabine Gruber, Markus Omann, Susanne Zeilinger: Comparative analysis of the repertoire of G protein-coupled receptors of three species of the fungal genus Trichoderma. BMC Microbiology 05/2013; 13(1):108., DOI:10.1186/1471-2180-13-108

  8. Lea Atanasova, Stephane Le Crom, Sabine Gruber, Fanny Coulpier, Verena Seidl-Seiboth, Christian P Kubicek, Irina S Druzhinina: Comparative transcriptomics reveals different strategies of Trichoderma mycoparasitism. BMC Genomics 02/2013; 14(1):121., DOI:10.1186/1471-2164-14-121

  9. Alexander W.A.F. Reismann, Lea Atanasova, Alexander Lichius, Sabine G. Gruber, Susanne Zeilinger, Gerhard J. Schuetz: Visualizing Signaling Complexes in Filamentous Fungi. Biophysical Journal 02/2017; 112(3):146a., DOI:10.1016/j.bpj.2016.11.801

  10. Alexa Frischmann, Susanna Neudl, Romana Gaderer, Klaus Bonazza, Simone Zach, Sabine Gruber, Oliver Spadiut, Gernot Friedbacher, Hinrich Grothe, Verena Seidl-Seiboth: Self-assembly at Air/Water Interfaces and Carbohydrate Binding Properties of the Small Secreted Protein EPL1 from the fungus Trichoderma atroviride. Journal of Biological Chemistry 12/2012; 288(6)., DOI:10.1074/jbc.M112.427633

  11. Sabine Gruber, Markus Omann, Carolina Escobar Rodrìguez, Theresa Radebner, Susanne Zeilinger: Generation of Trichoderma atroviride mutants with constitutively activated G protein signaling by using geneticin resistance as selection marker. BMC Research Notes 11/2012; 5(1):641., DOI:10.1186/1756-0500-5-641

  12. F Matarese, S Sarrocco, S Gruber, V Seidl-Seiboth, G Vannacci: Biocontrol of Fusarium head blight: Interactions between Trichoderma and mycotoxigenic Fusarium. Microbiology 01/2012; 158(Pt 1):98-106., DOI:10.1099/mic.0.052639-0

  13. Differential regulation of orthologous chitinase genes in mycoparasitic Trichoderma species. Gruber S, Kubicek CP, Seidl-Seiboth V. Appl Environ Microbiol. 2011 Oct;77(20):7217-26. doi: 10.1128/AEM.06027-11. Epub 2011 Aug 19. PMID: 21856825

  14. Christian P Kubicek, Alfredo Herrera-Estrella, Verena Seidl-Seiboth, Diego A Martinez, Irina S Druzhinina, Michael Thon, Susanne Zeilinger, Sergio Casas-Flores, Benjamin A Horwitz, Prasun K Mukherjee, Mala Mukherjee, László Kredics, Luis D Alcaraz, Andrea Aerts, Zsuzsanna Antal, Lea Atanasova, Mayte G Cervantes-Badillo, Jean Challacombe, Olga Chertkov, Kevin McCluskey, Fanny Coulpier, Nandan Deshpande, Hans von Döhren, Daniel J Ebbole, Edgardo U Esquivel-Naranjo, Erzsébet Fekete, Michel Flipphi, Fabian Glaser, Elida Y Gómez-Rodríguez, Sabine Gruber, Cliff Han, Bernard Henrissat, Rosa Hermosa, Miguel Hernández-Oñate, Levente Karaffa, Idit Kosti, Stéphane Le Crom, Erika Lindquist, Susan Lucas, Mette Lübeck, Peter S Lübeck, Antoine Margeot, Benjamin Metz, Monica Misra, Helena Nevalainen, Markus Omann, Nicolle Packer, Giancarlo Perrone, Edith E Uresti-Rivera, Asaf Salamov, Monika Schmoll, Bernhard Seiboth, Harris Shapiro, Serenella Sukno, Juan Antonio Tamayo-Ramos, Doris Tisch, Aric Wiest, Heather H Wilkinson, Michael Zhang, Pedro M Coutinho, Charles M Kenerley, Enrique Monte, Scott E Baker, Igor V Grigoriev: Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma. Genome biology 04/2011; 12(4):R40., DOI:10.1186/gb-2011-12-4-r40

  15. Verena Seidl-Seiboth, Sabine Gruber, Ugur Sezerman, Torsten Schwecke, Aydin Albayrak, Torsten Neuhof, Hans von Döhren, Scott E Baker, Christian P Kubicek: Novel Hydrophobins from Trichoderma Define a New Hydrophobin Subclass: Protein Properties, Evolution, Regulation and Processing. Journal of Molecular Evolution 03/2011; 72(4):339-51., DOI:10.1007/s00239-011-9438-3

  16. Sabine Gruber, Gustav Vaaje-Kolstad, Fabiola Matarese, Rubén López-Mondéjar, Christian P Kubicek, Verena Seidl-Seiboth: Analysis of subgroup C of fungal chitinases containing chitin-binding and LysM modules in the mycoparasite Trichoderma atroviride. Glycobiology 01/2011; 21(1):122-33., DOI:10.1093/glycob/cwq142

  17. Verena Seidl, Lifu Song, Erika Lindquist, Sabine Gruber, Alexeji Koptchinskiy, Susanne Zeilinger, Monika Schmoll, Pedro Martínez, Jibin Sun, Igor Grigoriev, Alfredo Herrera-Estrella, Scott E Baker, Christian P Kubicek: Transcriptomic response of the mycoparasitic fungus Trichoderma atroviride to the presence of a fungal prey. BMC Genomics 11/2009; 10(1):567., DOI:10.1186/1471-2164-10-567

  18. J Hermann, S Gruber, J B Neufeld, P Grundtner, M Graninger, W B Graninger, A Berghold, C Gasche: IL10R1 loss-of-function alleles in rheumatoid arthritis and systemic lupus erythematosus. Clinical and experimental rheumatology 07/2009; 27(4):603-8.

  19. Movadat, S Gruber, CA Agu, F Wrba, B Marian, C Gasche: Differentielle Expression von STAT3 und IL10R2 bei Kolorektalkarzinomen. Zeitschrift für Gastroenterologie 05/2009; 47(05)., DOI:10.1055/s-0029-1223944

  20. Sabine G Gruber, Maria Gloria Luciani, Paul Grundtner, Alexander Zdanov, Christoph Gasche: Differential signaling of cmvIL10 through common variants of the IL10 receptor 1. European Journal of Immunology 12/2008; 38(12):3365-75., DOI:10.1002/eji.200837718

  21. P Grundtner, S Gruber, S S Murray, S Vermeire, P Rutgeerts, T Decker, P L Lakatos, C Gasche: The IL-10R1 S138G loss-of-function allele and ulcerative colitis. Genes and immunity 10/2008; 10(1):84-92., DOI:10.1038/gene.2008.72

  22. Oliver Movadat, Sabine G. Gruber, Chukwuma A. Agu, Brigitte Marian, Friedrich Wrba, Christoph Gasche: M1623 Differential Expression of iL10r2, STAT1 and STAT3 in Colorectal Cancer. Gastroenterology 04/2008; 134(4)., DOI:10.1016/S0016-5085(08)61793-X

  23. Walter M Jaklitsch, Sabine Gruber, Hermann Voglmayr: Hypocrea seppoi, a new stipitate species from Finland. Karstenia 01/2008; 48(1):1-11., DOI:10.29203/ka.2008.423

  24. Thomas C Zechmeister, Alexander K T Kirschner, Martina Fuchsberger, Sabine G Gruber, Beate Suess, Renate Rosengarten, Fritz Pittner, Robert L Mach, Alois Herzig, Andreas H Farnleitner: Prevalence of Botulinum neurotoxin C1 and its corresponding gene in environmental samples from low and high risk avian botulism areas. 01/2005; 22(3):185-95.

Reviews

  1. Susanne Zeilinger, Sabine Gruber, Ravindra Bansal, Prasun K Mukherjee: Secondary metabolism in Trichoderma – Chemistry meets genomics. Fungal Biology Reviews 05/2016; 30(2)., DOI:10.1016/j.fbr.2016.05.001

  2. Sabine Gruber, Verena Seidl-Seiboth: Self versus non-self: Fungal cell wall degradation in Trichoderma. Microbiology 08/2011; 158(Pt 1):26-34., DOI:10.1099/mic.0.052613-0

Book chapters

  1. Kappel L, Gruber S. Chapter 12 - Chitin and chitosan—important structural components in Trichoderma cell wall remodeling. In: Gupta VK, Zeilinger S, Singh HB, Druzhinina I, editors. New and Future Developments in Microbial Biotechnology and Bioengineering: Elsevier; 2020. p. 243-80.

  2. Zeilinger S, Gruber S. Chapter 34 - Insights into Signaling Pathways of Antagonistic Trichoderma Species. In: Gupta VK, Schmoll M, Herrera-Estrella A, Upadhyay RS, Druzhinina I, Tuohy MG, editors. Biotechnology and Biology of Trichoderma. Amsterdam: Elsevier; 2014. p. 465-76.
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