Adolf Sandbichler

Wissenschaftlicher Assistent

Adolf Sandbichler


Adresse:
Institut für Zoologie
Universität Innsbruck

Technikerstr. 25
6020 Innsbruck
Österreich

Raum: 6/20
Telefon: +43 512 507-51868
E-Mail: adolf.sandbichler@uibk.ac.at

Aktuelle Forschung

Mein Interesse gilt dem Einfluss von Umweltstress, wie z.B. osmotischen Veränderungen oder Hypoxie, auf die Akklimation und Homöostase von primären Fischzellkulturen und Fischzelllinien. Dazu verwende ich moderne zellphysiologische Mess- und Imagingmethoden.

Weiters betreue ich die Laser Scanning Mikroskopie in Forschung und Lehre.

Weitere Details finden Sie unter:

Lehrveranstaltungen

im Masterstudium Molekulare Zell- und Entwicklungsbiologie.

Administrative Arbeit

Seit 2006 bin ich die Behindertenvertrauensperson für das wissenschaftliche Personal im Betriebsrat der Universität Innsbruck.

Curriculum vitae

2003 Mag. rer. nat., Diplomarbeit bei Bernd Pelster: Acid-base regulation in isolated gill cells of the goldfish (Carassius auratus). Institut für Zoologie, Universität Innsbruck
2004 Wissenschaftlicher Mitarbeiter i. A., Institut für Zoologie, Universität Innsbruck
2009 Dr. rer. nat., Dissertation bei Bernd Pelster: Transcriptional and Morphological Responses to Osmotic Stress in Trout Gill Cell Cultures: Dynamics of the Tight Junction Protein Claudin 28b and Cortical F-actin in Epithelial Adaptation. Institut für Zoologie, Universität Innsbruck
seit 2009 Wissenschaftlicher Assistent, Institut für Zoologie, Universität Innsbruck
2010
Teilnahme am "2nd IPMB ‐Workshop on Real‐time Monitoring of Cellular Metabolism using Cell Biosensor Chips" Institut für Pharmazie und Molekulare Biotechnologie, Ruprecht‐Karls‐Universität Heidelberg, Deutschland
2011 Teilnahme am "International Advanced Confocal Microscopy Course, Leica Microsystems, Mannheim, Deutschland" und am "Advanced Techniques in Laser Scanning Microscopy Course, Carl Zeiss Microimaging, Jena, Deutschland"
2012 Start Betrieb Leica SP5 II TCS Laser Scanning Mikroskop am Institut für Zoologie
Einschulung in das MoFlo Astrios (FACS) durch Beckman Coulter am Institut für Ökologie
2014 Einschulung in das Leica SP8 gatedSTED Superresolution Mikroskop der Innsbrucker Universitäten am CCB
2014
Etablierung der CellASIC ONIX (Merck Millipore) live cell imaging Plattform am Institut für Zoologie
2015 Etablierung des Seahorse XFp (Agilent Technologies) Zellphysiometers am Institut für Zoologie

 

Projekte

  • Reactive Oxygen Species and their role in the interaction between Circadian Clock and Hypoxic Signaling Pathway, Forschungsförderungsmittel der Nachwuchsförderung 2015 der Universität Innsbruck
  • Anpassung von Kiemenepithelzellen an osmotische Veränderungen, Tiroler Wissenschaftsfonds (TWF), 2005


Publikationen

Publikationen

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)
  • Egg, M.; Paulitsch, M.; Ennemoser, Y.; Wüstenhagen, A.; Schwerte, T.; Sandbichler, A. M.; Fiechtner, B.; Köblitz, L.; Prem, C.; Pelster, B. (2014): Chronodisruption increases cardiovascular risk in zebrafish via reduced clearance of senescent erythrocytes.
    In: CHRONOBIOLOGY INTERNATIONAL 31/5, S. 680 - 689. (DOI)

  • Leis, S.; Dresch, P.; Peintner, U.; Fliegerova, K.; Sandbichler, A.M.; Insam, H.; Podmirseg, S.M. (2014): Finding a robust strain for biomethanation: anaerobic fungi (Neocallimastigomycota) from the Alpine ibex (Capra ibex) and their associated methanogens.
    In: ANAEROBE 29, S. 34 - 43. (DOI) (Weblink)

  • Sandbichler, A.M.; Aschberger, T.; Pelster, B. (2013): A Method to Evaluate the Efficiency of Transfection Reagents in an Adherent Zebrafish Cell Line.
    In: BioResearch Open Access 2/1, S. 20 - 27. (DOI) (Weblink)

  • Egg, M.; Tischler, A.; Schwerte, T.; Sandbichler, A.; Folterbauer, C.; Pelster, B. (2012): Endurance exercise modifies the circadian clock in zebrafish (Danio rerio) temperature independently.
    In: Acta Physiologica 205/1, S. 167 - 176. (DOI) (Weblink)

  • Sandbichler, A.M.; Egg, M.; Schwerte, T.; Pelster, B. (2011): Claudin 28b and F-actin are involved in rainbow trout gill pavement cell tight junction remodeling under osmotic stress.
    In: Journal of Experimental Biology 214/9, S. 1473 - 1487. (DOI)

  • Sandbichler, A.M.; Farkas, J.; Salvenmoser, W.; Pelster, B. (2011): Cortisol affects tight junction morphology between pavement cells of rainbow trout gills in single-seeded insert culture.
    In: Journal of Comparative Physiology B: Biochemical, Systemic, and environmental physiology 181/8, S. 1023 - 1034. (DOI)

  • Kopp, R.; Schwerte, T.; Egg, M.; Sandbichler, A.M.; Egger, B.; Pelster, B. (2010): Chronic reduction in cardiac output induces hypoxic signaling in larval zebrafish even at a time when convective oxygen transport is not required.
    In: PHYSIOLOGICAL GENOMICS 42a, S. 8 - 23. (DOI)

  • Martien, R.; Loretz, B.; Sandbichler, A.M.; Bernkop-Schnürch, A. (2008): Thiolated chitosan nanoparticles: transfection study in the Caco-2 differentiated cell culture.
    In: NANOTECHNOLOGY 19, S. 1 - 9.

  • SANDBICHLER, AM.; PELSTER, B. (2004): Acid-Base Regulation in Isolated Gill Cells of the Goldfish (Carassius auratus).
    In: Journal of Comparative Physiology B: Biochemical, Systemic, and environmental physiology 174/8, S. 601 - 610.

Zeitschriftenaufsatz (Review)
  • Sandbichler, A.M.; Höckner, M. (2016): Cadmium Protection Strategies-A Hidden Trade-Off?
    In: International Journal Of Molecular Sciences 17/1, No. 139. (DOI) (Weblink)

Zeitschriftenbeitrag (Meeting-Abstract)
  • Sandbichler, A. M.; Schwerte, T.; Pelster, B. (2009): Cortisol-dependent remodelling of tight junction claudin 28b and cortical F-actin in cultured gill epithelia of rainbow trout.
    In: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY 154/1 (Supplement 1), S. S29.

  • Aigner, M.; Botta, M.; Sandbichler, A.; Salvenmoser, W.; Egger, B.; Rieger, R.; Gschwentner, R. (2005): Development of a basal medium for primary cell culture of marine flatworms.
    In: Berichte des Naturwissenschaftlich-Medizinischen Vereins in Innsbruck 16, S. 20.

  • Sandbichler, AM.; Egg, M.; Pelster, G.B. (2005): Osmolarity-induced changes in trout gill epithelial cells on permeable supports.
    In: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY 141/Supplement 1, S. 197.



Vorträge

Präsentationen auf Kongressen, Tagungen o.Ä.

Konferenzvortrag (auf persönliche Einladung)
  • Vortragende/r: Egg, M. Co-AutorInnen: Sandbichler, A.: Linking oxygen to time: The impact of oxygen availability on the circadian clock in zebrafish.
    The 29th Conference of the International Society for Chronobiology (ISC), Suzhou, 26.10.2016. (Weblink)

Konferenzvortrag (auf Einreichung / Anmeldung)
  • Vortragende/r: Egg, M. Co-AutorInnen: Schwerte, T.; Sandbichler, A.M.; Pelster, B.: Linking time to oxygen: The cross-talk between the Circadian Clock and the Hypoxic Signaling Pathway.
    Society for Experimental Biology Annual Meeting 2014, Manchester, 03.07.2014. (Weblink)

  • Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Nagy, J.; Egg, M.: Differential hypoxic response of the circadian clock: attenuation versus phase shift.
    Society for Experimental Biology Annual Meeting 2014, Manchester, 03.07.2014. (Weblink)

  • Vortragende/r: Leis, S. Co-AutorInnen: Dresch, P.; Peintner, U.; Fliegerová, K.; Sandbichler, A.M.; Insam, H.; Podmirseg, S.M.: Isolation and identification of anaerobic fungi (Neocallimastigomycota) from an alpine herbivore, the capricorn (Capra ibex).
    8th International Symposium on Anaerobic Microbiology (ISAM8), Innsbruck, 13.06.2013.

  • Vortragende/r: Sandbichler, A.: Osmolarity-induced changes in trout gill epithelial cells on permeable supports.
    SEB Annual Main Meeting 2005, Barcelona, 11.07.2005.

Posterpräsentation
  • Vortragende/r: Lamberti, G. Co-AutorInnen: Laschober, G.; Sopper, S.; Sandbichler, A.M.; Trajanoski, Z.: Metabolic characterization of human T-cells during differentiation.
    9th ÖGMBT Annual Meeting & 8th Life Science Meeting Innsbruck, Innsbruck, 26.09.2017. (Weblink)

  • Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Vorhauser, J.; Geng, A.: Peroxisomes and their role in cellular redox balance in zebrafish fibroblasts.
    9th ÖGMBT Annual Meeting & 8th Life Science Meeting Innsbruck, Innsbruck, 26.09.2017. (Weblink)

  • Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Tschugg, Bettina; Sturm, Edith; Sandbichler, Adolf M.; Stefanova, Nadia; Koschak, Alexandra: The Neuroretina in Multiple System Atrophy.
    5th Annual SFB Meeting 2016, Vill, 30.11.2016. (Weblink)

  • Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Tschugg, Bettina; Sturm, Edith; Sandbichler, Adolf M.; Stefanova, Nadia; Koschak, Alexandra: The Neuroretina in Multiple System Atrophy.
    22nd Scientific Symposium of the Austrian Pharmacological Society (APHAR), Wien, 09.09.2016. (Weblink)

  • Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Tschugg, Bettina; Sturm, Edith; Sandbichler, Adolf M.; Stefanova, Nadia; Koschak, Alexandra: The Neuroretina in Multiple System Atrophy: Atrophy Morphological and Functional Aspects in Plp-α-Syn Mice.
    10th FENS Forum of Neuroscience, Kopenhagen, 06.07.2016. (Weblink)

  • Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Tschugg, Bettina; Sturm, Edith; Sandbichler, Adolf M.; Stefanova, Nadia; Koschak, Alexandra: Retinal immunoreactivity in a mouse model of multiple system atrophy.
    6th Annual CMBI Meeting Innsbruck, Gnadenwald, 04.03.2016. (Weblink)

  • Vortragende/r: Kaehler, K. Co-AutorInnen: Seitter, H.; Knoflach, D.; Sturm, E.; Sandbichler, A.; Stefanova, N.; Koschak, A.: Retinal pathomorphology in a mouse model of multiple system atrophy.
    European Retina Meeting 2015, Brighton, 01.10.2015. (Weblink)

  • Vortragende/r: Muik, M. Co-AutorInnen: Gomez-Brandon, M.; Sandbichler, A.M.; Insam, H.; Wett, B.; Podmirseg, S.M.: Characterization of anammox granules from a full-scale WWTP by microscopic techniques and a novel particle tracking method.
    8th International Symposium on Anaerobic Microbiology (ISAM8), Innsbruck, 12.06.2013.

  • Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Scheidnagl, S.; Selcuk, D.; Rainer, D.; Pelster, B.; Egg, M.: Mitochondrial plasticity in zebrafish fibroblasts exposed to hypoxia.
    Mitochondrial Trafficking and Function in Health and Disease, Boston, 25.06.2012. (Weblink)

  • Vortragende/r: Schredelseker, T. Co-AutorInnen: Schneebauer, G.; Sandbichler, A.M.; Meyer, D.; Schwerte, T.: Analysis of mechanisms to survive oxygen deprivation in vivo and in vitro.
    Swiss and Upper Rhine Valley (SURV) Zebrafish Meeting 2012 (Zebrafish 2012), Basel, 13.04.2012. (Weblink)

  • Vortragende/r: Sandbichler, A.; Schwerte, T.; Pelster, B.: Cortisol-dependent remodelling of tight junction claudin 28b and cortical F-actin in cultured gill epithelia of rainbow trout.
    26th ESCPB Congress of the new European Society for Comparative Physiology and Biochemistry, Innsbruck, 06.09.2009.

  • Vortragende/r: Sandbichler, AM.; Schwerte, T.; Pelster, B.: Osmolarity-dependent remodelling of barrier properties in trout gill cell layers.
    4th Annual Meeting of the Center of Molecular Biosciences (CMBI), Igls, 28.09.2007.

  • Vortragende/r: Aigner, M.; Botta, M.; Sandbichler, A.; Salvenmoser, W.; Egger, B.; Rieger, R.; Gschwentner, R.: Development of a basal medium for primary cell culture of marine flatworms.
    10th International Symposium on Flatworm Biology (ISFB 2006), Innsbruck, 29.07.2006.

  • Vortragende/r: Sandbichler, A.; Egg, M.; Pelster, B.: The influence of apical hypoosmotic stress on the expression of cytoskeletal components in trout gill epithelial cells.
    7th International Congress on the Biology of Fish (ICBF VII), St. John’s, 18.07.2006.

  • Vortragende/r: Sandbichler, A.; Egg, M.; Pelster, B.: Transcriptional response to apical osmotic stress in trout gill epithelial cells.
    2nd Annual Meeting of the Center for Molecular Biosciences (CMBI), Vill, 30.09.2005.

  • Vortragende/r: Sandbichler, A.; Egg, M.; Pelster, B.: Transcriptional response to apical osmotic stress in trout gill epithelial cells.
    SEB Annual Main Meeting 2005, Barcelona, 11.07.2005.



Projekte, Stipendien und sonstige Drittmittel

Projekte

  • Sandbichler, Adolf: Reactive Oxygen Species and their role in the interaction between Circadian Clock and Hypoxic Signaling Pathway.
    Leopold-Franzens-Universität Innsbruck - Vizerektorat für Forschung, Nachwuchsfördermittel aus der Nachwuchsförderung der LFU
    01.01.2016 - 31.05.2018

  • Sandbichler, Adolf: Anpassung von Kiemenepithelzellen an osmotische Veränderungen.
    Tiroler Wissenschaftsfonds (TWF)
    03.11.2005 - 29.02.2008


Vorträge und Poster

  • Sandbichler AM, Nagy J and Egg M: Differential hypoxia response of the circadian clock: attenuation versus phase shift. Society of Experimental Biology Meeting 2014, Manchester, UK
  • Sandbichler AM, Scheidnagl S, Selcuk D, Rainer D, Pelster B, Egg M: Mitochondrial plasticity in zebrafish fibroblasts exposed to hypoxia. Mitochondrial Trafficking and Function in Health and Disease, Boston, MA, USA; 25. - 26. Juni 2012
  • Schredelseker T, Schneebauer G, Sandbichler A, Meyer D and Schwerte T (2012): Analysis of mechanisms to survive oxygen deprivation in vivo and in vitro. Swiss and Upper Rhine Valley (SURV) Zebrafish meeting, Basel
  • Sandbichler AM, Schwerte T and Pelster B (2009): Cortisol-dependent remodelling of tight junction claudin 28b and cortical F-actin in cultured gill epithelia of rainbow trout. 26th ESCPBnew Congress 2009, Innsbruck, Austria. Comp. Biochem. Physiol. A, 154 (2009);
  • Sandbichler AM, Egg M and Pelster B (2006): The influence of apical hypoosmotic stress on the expression of cytoskeletal components in trout gill epithelial cells. VIIth International Congress on the Biology of Fish 2006, St. John's, Newfoundland, Canada. Session Ion and Acid-Base Regulation in Fish;
  • Sandbichler AM, Egg M and Pelster B (2005): Osmolarity-induced changes in trout gill epithelial cells on permeable supports. SEB Annual Main Meeting 2005, Barcelona, Spain. Session A 11 General Animal Physiology. Comp. Biochem. Physiol. A, 141 (2005), 189 - 218;