Publikationen in internationalen Fachzeitschriften (peer-reviewed)


  • Strecker, K., Sim, E.-J., Woike, K., Schönfeldt-Lecuona, C., Radermacher, P., Karabatsiakis, A., Kiefer, M., Association of the biopsychosocial factors adverse childhood experiences, adult attachment style, emotion regulation and mitochondrial biogenesis with major depressive disorder (submitted).
  • de Punder, K., Juan Salinas-Manrique, J., Dietrich, D.E., Karabatsiakis, A. Serum levels of the steroid hormone dehydroepiandrosterone (DHEA) are associated with psychological trauma and lymphocyte telomere integrity in women suffering from depression (Neuroimmunomodulation). DOI: 10.1159/000538893
  • de Punder, K. & Karabatsiakis, A. (2024). Age-related disease: Immune system; Chapter of the book AGING (edited by Michael Fossel). ISBN: 978-0-443-15500-0.
  • Golubnitschaja, O., Polivka, J. Jr., Potuznik, P.,  Pesta, M., Stetkarova, I.,  Mazurakova, A., Lackova, L., Kubatka, P., Kropp, M., Thumann, G., Erb, C.,  Fröhlich, H., Wang, W.,  Baban, B., Kapalla, M., Shapira, N., Richter, K., Karabatsiakis, A., Ivica Smokovski, I., Leonard Christopher Schmeel, L. C., Eleni Gkika, E., Friedemann, Paul, F., Parini, P., Polivka, J.. The paradigm change from reactive medical services to 3PM in ischemic stroke: a holistic approach utilising tear fluid multi‑omics, mitochondria as a vital biosensor and AI‑based multi‑professional data interpretation. EPMA Journal


  • Fissler, P., Vandersmissen, A., Filippi, M., Mavioglu, R. N., Scholkmann, F., Karabatsiakis, A., & Krähenmann, R. (2023). Effects of serotonergic psychedelics on mitochondria: Transdiagnostic implications for mitochondria-related pathologies. Journal of Psychopharmacology, 026988112311647.
  • Karrasch, S., Mavioğlu, R.N., Matits, L., Gumpp, A.M., Mack, M., Behnke, A., Tumani, V., Karabatsiakis, A., Bongartz, W., Iris-Tatjana Kolassa, ITK. (2023). Randomized controlled trial investigating potential effects of relaxation on mitochondrial function in immune cells: A pilot experiment, Biological Psychology, Volume 183, 108656,
  • Kroener J, Schaitz C, Karabatsiakis A, Maier A, Connemann B, Schmied E, Sosic-Vasic Z. Relationship Dysfunction in Couples When One Partner is Diagnosed with Borderline Personality Disorder: Findings from a Pilot Study. Behavioral Sciences. 2023; 13(3):253. doi: 10.3390/bs13030253.
  • Köhler-Dauner F., Mayer I, Hitzler M, Karabatsiakis A, Matits L, Fegert JM, Kolassa IT, Ziegenhain U. Atypical maternal interaction is associated with elevated levels of hair cortisol in children. Frontiers in Pediatrics. 10:004882. doi:10.3389/fped.2022.994882.


  • Köhler-Dauner F., Mayer I, Hitzler M, Karabatsiakis A, Matits L, Fegert JM, Kolassa IT, Ziegenhain U (in press). Atypical maternal interaction is associated with elevated levels of hair cortisol in children. Frontiers in Pediatrics.

  • Golubnitschaja O, Potuznik P, Polivka Jr. J, Pesta M, Kaverina O, Pieper CC, Kropp M, Thumann G, Erb C, Karabatsiakis A, Stetkarova I, Polivka J, Costigliola V.Ischemic stroke of unclear aetiology: A case-by-case analysis and call for a multi-professional predictive, preventive and personalised approach. EPMA Journal.

  • Mavioglu RN, Ramo-Fernandez L, Gumpp AM, Kolassa I-T and Karabatsiakis A (2022). A history of childhood maltreatment is associated with altered methylation levels of DNA methyltransferase 1 in maternal but not in neonatal mononuclear immune cells. Front. Psychiatry 13:945343. doi: 10.3389/fpsyt.2022.945343

  • Karabatsiakis, A, de Punder, K, Salinas-Manrique, J. et al. Hair cortisol level might be indicative for a 3PM approach towards suicide risk assessment in depression: comparative analysis of mentally stable and depressed individuals versus individuals after completing suicide. EPMA Journal (2022).

  • Karabatsiakis A, de Punder K, Doyen-Waldecker C, Ramo-Fernández L, Krause S, Gumpp AM, Bach AM, Fegert JM, Kolassa I-T, Gündel H, Ziegenhain U, Buchheim A. Reactivity of the Oxytocinergic and Neuroendocrine System Following the Adult Attachment Projective Picture System in Men of Recent Fatherhood: Results from an Exploratory Pilot Study with a Cross-Sectional Design. Brain Sciences. 2022; 12(10):1314.

  • Buchheim A, Ziegenhain U, Kindler H, Waller C, Gündel H, Karabatsiakis A and Fegert J (2022) Identifying Risk and Resilience Factors in the Intergenerational Cycle of Maltreatment: Results From the TRANS-GEN Study Investigating the Effects of Maternal Attachment and Social Support on Child Attachment and Cardiovascular Stress Physiology. Front. Hum. Neurosci. 16:890262. doi: 10.3389/fnhum.2022.890262

  • Gumpp, A. M., Behnke, A., Ramo-Fernández, L., Radermacher, P., Gündel, H., Ziegenhain, U., Karabatsiakis, A., Kolassa, I.-T. (in press). Investigating mitochondrial respiration and density in peripheral blood mononuclear cells of women with childhood maltreatment history from the post-parturition period to one-year follow-up. [published online ahead of print, 2022 Mar 21]. Psychol Med. 2022;1-12. https:\\doi:10.1017/S0033291722000411

  • Bertele, N., Karabatsiakis, A., Talmon, A., Buss, C. Biochemical clusters predict mortality and reported inability to work 10 years later. Brain, Behavior, & Immunity - Health (in press), 2022, 100432.

  • Gander, M., Karabatsiakis, A., Nuderscher, K., Bernheim, D., Doyen-Waldecker, C., Buchheim, A. (2022). Secure Attachment Representation in Adolescence Buffers Heart-Rate Reactivity in Response to Attachment-Related Stressors. Frontiers in Human Neuroscience, Volume 16. DOI=10.3389/fnhum.2022.806987


  • Bertele, N., Karabatsiakis, A., Buss, C., Talmon, A. How biomarker patterns can be utilized to identify individuals with a high disease burden: a bioinformatics approach towards predictive, preventive, and personalized (3P) medicine. EPMA Journal 12 (4), 507–516 (2021).

  • Ramo-Fernandez, L., Gumpp, M., Boeck, C., Krause, S., Bach, A., Waller, C., Kolassa, I.-T., Karabatsiakis, A. Associations between childhood maltreatment and DNA methylation of the oxytocin receptor gene in immune cells of mother-newborn dyads. Translational Psychiatry 11 (1), 449 (2021). DOI:

  • Golubnitschaja, O., Liskova, A., Koklesova, L., Samec, M., Biringer, K., Büsselberg, D., Podbielska, H., Kunin, A. A., Evsevyeva, M. E., Shapira, N., Paul, F., Erb, C., Dietrich, D. E., Felbel, D., Karabatsiakis, A., Bubnov, R., Polivka, J., Polivka Jr, , Birkenbihl, C., Fröhlich, H., Hofmann-Apitius, M., Kubatka, P. Caution, “normal” BMI: health risks associated with potentially masked individual underweight—EPMA Position Paper 2021. EPMA Journal 12 (3).

  • Karabatsiakis, A.*, Störkel, L. M.*, Hepp, J., Kolassa, -T., Schmahl, C., Niedtfeld, I. Salivary beta-endorphin in non-suicidal self-injury: an ambulatory assessment study. Neuropsychopharmacology 46 (7), 1357–1363 (2021). (* equal contribution)

  • Ramo-Fernández, L., Karabatsiakis, A., Boeck, C., Bach, M., Gumpp, A. M., Mavioglu, R. N., Ammerpohl, O., Kolassa, I.-T., 2021. Characterization of the effects of age and childhood maltreatment on ELOVL2 DNA methylation. Development and Psychopathology, 1-11.


  • Behnke, A., Karabatsiakis, A., Krumbholz, A., Karrasch, S., Schelling, G., Kolassa, I.T., Rojas, R., 2020. Profiling hair cortisol and endocannabinoid levels in Emergency Medical Services personnel: Its association with workload, trauma exposure, and health. Scientific Reports 10, 22403 (2020).

  • Leichsenring, F., Weidner, K., Beutel, M., Knaevelsrud, C., Hoyer, J., Kruse, J., Stark, R., Salzer, S., Steinert, C., Woeller, W., Hermann, A., Koenig, H., Peters, E., Kolassa, I.T., Von Wietersheim, J., Guendel, H., Karabatsiakis, A., Schade-Brittinger, C., Reese, J.P., Reuß, A., Feix, L.A., Schuster, P. "Trauma-focused psychodynamic therapy and STAIR Narrative Therapy of post-traumatic stress disorder related to childhood maltreatment: trial protocol of a multicenter randomized controlled trial assessing psychological, neurobiological and health economic outcomes (ENHANCE)". BMJ Open  2020;10.

  • Gumpp, A., Boeck, C., Behnke, A., Bach, A.M., Ramo-Fernandez, L., Welz, T., Gündel, H., Kolassa, I.T. & Karabatsiakis, A., 2020. Childhood maltreatment is associated with changes in mitochondrial bioenergetics in maternal, but not in neonatal immune cells. Proceedings of the National Academy of Sciences of the United States of America (PNAS)

  • Karabatsiakis, A., Schönfeldt-Lecuona, 2020. Depression, mitochondrial bioenergetics, and electroconvulsive therapy: a new approach towards personalized medicine in psychiatric treatment - a short review and current perspective. Translational Psychiatry, 10(1):226.DOI: 10.1038/s41398-020-00901-7

  • Karabatsiakis, A., Woike, K., Behnke, A., Kolassa, I.T., Schoenfeldt-Lecuona, C., Kiefer, M., Sim, E., 2020. Testing the reversibility of impaired mitochondrial bioenergetic functioning in peripheral blood mononuclear cells from depressed patients by clinical-routine antidepressant treatment. Journal of Psychosomatic Research 133: 110086. DOI: 10.1016/j.jpsychores.2020.110086

  • Karabatsiakis, A., Todt, M., Salinas-Manrique, J., Buchheim, A., Dietrich, D., 2020. Comparison of hair cortisol concentrations between depressed patients, suicide completers, and control subjects: A predictive biochemical indicator for suicide risk in depression? Journal of Psychosomatic Research Volume 133, DOI:10.1016/j.jpsychores.2020.110093

  • Schultchen, D., Küchler, A-M., Schillings, C., Weineck, F., Karabatsiakis, A., Ebert, D.D., Baumeister, H., Pollatos, H., 2020. Effectiveness of a guided online mindfulness-focused intervention in a student population: Study protocol for a randomized control trial. BMJ Open, 24;10(3):e032775. DOI: 1136/bmjopen-2019-032775

  • Hitzler, M., Karrasch, S., Gumpp, A. M., Karabatsiakis, A., Kolassa, I.-T., 2020. Molekulartoxische Folgen von chronischem und traumatischem Stress für die psychosomatische Gesundheit und deren Reversibilität durch Entspannungsverfahren. Verhaltenstherapie; 30(1): 29-43. DOI:10.1159/000505380

  • Behnke, A., Rojas, R., Karabatsiakis, A., Kolassa, I.-T., 2020. Childhood maltreatment compromises resilience against occupational trauma exposure: A retrospective study among emergency medical service personnel. Child Abuse & Neglect, 99, e104248. DOI: 10.1016/j.chiabu.2019.104248


  • Karabatsiakis, A., Hitzler, M., Kolassa, I.T., 2019. Biomolekulare Vulnerabilitätsfaktoren psychischer Erkrankungen. Einfluss von chronischem und traumatischem Stress auf Immunsystem, freie Radikale und Mitochondrien. Der Psychotherapeut 64: 329. DOI: 10.1007/s00278-019-0366-9

  • Fischer, D., Messner, M., Karabatsiakis, A., Schillings, C. & Pollatos, O., 2019. Effects of an 8week body scan intervention on individually perceived psychological stress and related steroid hormones in hair. Mindfulness, 10: 2532-2543. DOI: 10.1007/s12671-019-01222-7

  • Nold, V., Sweatman, C., Karabatsiakis, A., Böck, C., Bretschneider, T., Lawless, N., FundelClemens, K., Kolassa, I.T., Allers, K.A., 2019. Activation of the Kynurenine Pathway and Mitochondrial Respiration to Face Allostatic Load in a Double-Hit Model of Stress. Psychoneuroendocrinology 107:148-159. DOI: 10.1016/j.psyneuen.2019.04.006

  • Ramo-Fernandez, L., Boeck, C., Koenig, A., Schury, K., Binder, E.B., Gündel, H., Fegert, J.M., Karabatsiakis, A., Kolassa, I.-T., 2019. The effects of childhood maltreatment on epigenetic regulation of stress-response associated genes: an intergenerational approach. Scientific Reports 9:983. DOI: 1038/s41598-018-36689-2


  • Geiger, M., Boeck, C., Koenig, A.M., Schury, K., Waller, C., Kolassa, S., Karabatsiakis, A., Kolassa, IT, 2018. Investigating the effects of childhood maltreatment on proinflammatory signaling: The influence of cortisol and DHEA on cytokine secretion ex vivo. Mental Health & Prevention 13: 176-186. DOI:10.1016/j.mhp.2018.04.002

  • Karabatsiakis, A., Schoenfeldt-Lecuona, C., 2018. Depressionen als Stoffwechselstörung: Die Rolle der Mitochondrien. Nervenheilkunde 37(12): 873-879. 

  • Koenig, A.M., Ramo-Fernandez, L., Boeck, C., Umlauft, M., Pauly, M., Binder, E.B., Kirschbaum, C., Gündel, H., Karabatsiakis, A., Kolassa, I.-T., 2018. Intergenerational gene x environment interaction of FKBP5 and childhood maltreatment on hair steroids. Psychoneuroendocrinology 5(92):103-112. DOI: 1016/j.psyneuen.2018.04.002

  • Conrad, C., Wilker, S., Schneider, A., Karabatsiakis, A., Pfeiffer, A., Kolassa, S., Freytag, V., Vukojevic, V., Vogler, C., Milnik, A., Papassotiropoulos, A., de Quervain, D.J.-F., Elbert, T., Kolassa, I.-T., 2018. Integrated genetic, epigenetic, and genes enrichment analyses identify NOTCH as a potential mediator for PTSD risk after trauma: Preliminary results from independent African cohorts. Psychophysiology e13288. DOI: 10.1111/psyp.13288

  • Böck, C., Gumpp, A.M., Calzia, E., Radermacher, P., Waller, C., Karabatsiakis, A., Kolassa, I.-T., 2018. The association between cortisol, oxytocin and immune cell mitochondrial oxygen consumption in postpartum women with childhood maltreatment. Psychoneuroendocrinology 96:69-77. DOI: 1016/j.psyneuen.2018.05.040

  • Böck, C., Salinas-Manrique, J., Calzia, E., Radermacher, P., von Arnim, C. A. F., Dietrich, D.E., Kolassa, I.-T., Karabatsiakis, A., 2018. Targeting the association between telomere length and immuno-cellular bioenergetics in female patients with major depressive disorder. Scientific Reports 8(1): 9419. DOI: 1038/s41598-018-26867-7

  • Krause, S., Böck, C., Gumpp, A.M., Rottler, E., Schury, K., Karabatsiakis, A., Buchheim, A., Guendel, H., Kolassa, I-T., Waller, C., 2018. Child maltreatment is associated with a reduction of the oxytocin repector in peripheral blood mononuclear cells. Frontiers in Psychology 9:173. DOI: 10.3389/fpsyg.2018.00173

  • Karabatsiakis1, A., König1, A.M., Stoll, T., Wilker, S., Hennessy, T., Hill, M.M., Kolassa, I.T., 2018. Serum profile changes in postpartum women with a history of childhood maltreatment: a combined metabolite and lipid fingerprinting study. Scientific Reports (8):3468. DOI: 1038/s41598-018-21763-

  • König, A.M., Gao, W., Umlauft, M., Schury, K., Reister, F., Kirschbaum, C., Karabatsiakis, A., Kolassa, I.T., 2018. Altered hair endocannabinoid levels in mothers with childhood maltreatment and their newborns. Biological Psychology 135:93-101. DOI: 1016/j.biopsycho.2018.03.006

  • Böck, C., Pfister, S., Bürkle, A., Vanhooren, V., Libert, C., Salinas-Manrique, J., Dietrich, D.E., Kolassa, I.T., Karabatsiakis, A., 2018. Alterations of the serum N-glycan profile in female patients with Major Depressive Disorder. Journal of Affective Disorders (234):139-147. DOI: 1016/j.jad.2018.02.082


  • Schury, K., König, A.M., Isele, D., Hulbert, A.L., Krause, S., Umlauft, M., Kolassa, S., Ziegenhain, U., Karabatsiakis, A., Reister, F., Guendel, H., Fegert, J.M., and Kolassa. I.-T., 2017. Alterations of hair cortisol and dehydroepiandrosterone in mother-infant-dyads with maternal childhood maltreatment. BMC Psychiatry, 17:213. DOI: 1186/s12888-017-1367-2.

  • Küster, O.C., Laptinskaya, D., Fissler, P., Schnack, P., Zuegel, M., Nold, V., Thurm, F., Pleiner, S., Karabatsiakis, A., von Einem, B., Weydt, P., Liesener, A., Borta, A., Woll, A., Hengerer, B., Kolassa, I.-T., von Arnim, C.A.F., 2017.  Novel Blood-Based Biomarkers of Cognition, Stress, and Physical or Cognitive Training in Older Adults at Risk of Dementia: Preliminary Evidence for a Role of BDNF, Irisin, and the Kynurenine Pathway. Journal of Alzheimer’s Disease, 59(3):1097-1111. DOI: 3233/JAD-17044

  • Böck, C., Krause, S., Karabatsiakis, A., Schury, K., Gündel, H., Waller, C., Kolassa, I.-T., 2017. History of child maltreatment and telomere length in immune cells subsets: Associations with stress- and attachment-related hormones. Development and Psychopathology, 1-13. DOI: 10.1017/S0954579417001055


  • Krause, S., Pokorny, D., Schury, K., Doyen-Waldecker, C., Hulbert, A-L., Karabatsiakis, A., Kolassa. I-T., Gündel, H., Waller, C., Buchheim, A., 2016. Effects of the Adult Attachment Projective Picture System on Oxytoxin and Cortisol Blood Levels in Mothers. Frontiers in Human Neuroscience, 10:627.  DOI: 3389/fnhum.2016.00627

  • Böck, C., Koenig, A.M., Schury, K., Geiger, M.L., Karabatsiakis, A., Wilker, S., Waller, C., Gündel, H., Fegert, J.M., Calzia, E., Kolassa, I.T, 2016. Inflammation in adult women with a history of child maltreatment: The involvement of mitochondrial alterations and oxidative stress. Mitochondrion, 30:197-207. DOI: 1016/j.mito.2016.08.006

  • Wilker, S., Pfeiffer, A., Elbert, T., Ovuga, E., Karabatsiakis, A., Krumbholz, A., Thieme, D., Schelling, G., Kolassa, I.T., 2016. Endocannabinoid concentrations in hair are associated with PTSD symptom severity. Psychoneuroendocrinology, 67:198-206. DOI: 1016/j.psyneuen.2016.02.010

  • Linkus, B., Wiesner, D., Meßmer, M., Karabatsiakis, A., Scheffold, A., Rudolph, K.L., Thal, D., Weishaupt, J.H., Ludolph, A.C., Danzer, K.M., 2016. Telomere shortening leads to earlier age of onset in ALS mice. Aging, 8(2):282-393. DOI: 10.18632/aging.100904  

  • Krause, S., Hulbert, AL, Schury, K., Buchheim, A., Karabatsiakis, A., Kolassa, I.T, Guendel, H., Waller, C., 2016. Gradual Activation of the Binding System leads to increased Release of Oxytocin in Mothers: What Role an early Binding Traumatization plays? Zeitschrift für Psychosomatische Medizin und Psychotherapie, 61(1):74.


  • Brunner, R., Reichl, C., Bermpohl, F., Bertsch, K., Bock, J., Bödeker, K., Firk, C., Fuchs, A., Führer, D., Gröger, N., Heinz, A., Herpertz-Dahlmann, B., Herpertz, S. C., Dahmen, B., Hindi, Attar, C., Kluczniok, D., Konrad, K., Lehmkuhl, U., Möhler, E., Neukel, C., Reck, C., Resch, F., Rether, K., Zietlow, A.-L., Ziegenhain, U., Schury, K., Karabatsiakis, A., Braun, K., Gündel, H., Kindler, H., Buchheim, A., Meysen, T., Kolassa, I.T., Fegert, J. M., 2015. Mechanismen der transgenerationsübergreifenden Transmission belastender Kindheitserfahrungen. Trauma und Gewalt, Theoretischer Hintergrund, Forschungsdesigns und erste Ergebnisse zweier multizentrischer Studien in Deutschland, 2(9), 134-147.

  • Karabatsiakis, A.1, Hamuni, G.1, Wilker, S.1, Kolassa, S., Renu, D., Kadereit, S., Schauer, M., Hennessy, T., & Kolassa, I.T., 2015. Metabolite profiling in posttraumatic stress disorder. Journal of Molecular Psychiatry, 3(1):2. DOI: 10.1186/s40303-015-0007-3

  • Böck, C., Karabatsiakis, A., Kolassa, I.T., 2014. Biologische Grundlagen der Depression – Mitochondriale Funktionalität als Ansatzpunkt. Zeitschrift für Medizin-Ethik-Recht, 2, Jg.5.


  • Karabatsiakis, A., Böck, C., Manrique, J.S., Kolassa, S., Calzia, E., Dietrich, D.E., & Kolassa, I.T., 2014. Mitochondrial respiration in peripheral blood mononuclear cells correlates with depressive subsymptoms and severity of major depression. Translational Psychiatry, 4, e397. DOI: 10.1038/tp.2014.44.

  • Karabatsiakis, A., Kolassa, I.T., Kolassa, S., Rudolph, K.L., & Dietrich D.E., 2014. Telomere shortening in leukocyte subpopulations in depression. BMC Psychiatry, 14:192. DOI: 10.1186/1471-244X-14-192.


  • Hauer, D., Schelling, G., Gola, H., Campolongo, P., Morath, J., Roozendaal, B., Hamuni, G., Karabatsiakis, A., Atsak, P., Vogeser, M., Kolassa, I.T., 2013. Plasma Concentrations of Endocannabinoids and Related Fatty Acid Amides in Patients with Post-Traumatic Stress Disorder. PLOS One, 8(5), e62741. DOI: 10.1371/journal.pone.0062741


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