Ute Rothbächer
Associate Professor
Address:
Department of Zoology
University of Innsbruck
Technikerstr. 25
6020 Innsbruck
Austria
Room: 7/09
Current Research
How the dynamic developmental program is inscribed in the genome and inherited to subsequent generations remains poorly understood. Efficient functional readout, notably at DNA level in vivo is often complicated by the complexity of regulatory interactions and the complexity of genomes, particularly in vertebrates.
To unravel fundamental genetic mechanisms that control cell fate choice in vivo, we study embryonic development in a simple marine invertebrate, the ascidian Ciona intestinalis, belonging to the vertebrate sister group, the tunicates. Larval equivalent stages of ascidians and vertebrates have resembling structures such as a central notochord (embryonic structure forming the vertebral colomn in vertebrates), flanking muscles, a dorsal neural tube and notably a head with sensory organs that may be related to the greatly expanded sensory epithelia in vertebrates. The latter ‘new head’ of vertebrates likely evolved towards their successful predatory lifestyle. Whats more, ascidian embryos develop with a fixed cellular lineage based on few and large cells allowing cellular resolution of cell fate identity. The fully sequenced genome, since compact and unduplicated, gives acces to regulatory DNA segments, isolated for reporter gene essays in vivo. Such DNA constructs, when electroporated in fertilised eggs, produce transiently transgenic embryos and allow rapid gene functional and gene regulatory analyses, in precisely identifyable tissue precursors, from earliest embryonic stages in vivo.
Our research aims on deciphering embryonic gene network signatures in ascidians are:
1) the mechanisms and dynamics for gene regulatory switches affecting the pluripotent ectoderm in vivo giving rise to neural precursors. These form head sensory organs including the sensory vesicle (brain, light, gravity) and the papillae (sensory adhesive organ, for settlement and metamorphosis). We focus on novel combinatorial codes and repressive activities of nuclear effectors for major signaling pathways, notably Wnt and FGF/MEK signaling influencing the cell fate choice of neural precursors.
2) the genetic and molecular basis for ascidian bioadhesion (via their larval sensory adhesive organ, the papillae) motivated by the search for novel biomimetic reagents.
JOVE Movie: Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis
newsroom 2022 (in German): Wichtiger Ursprung unserer Sinne identifiziert
newsroom 2024 (in German): Molekulare Einblicke in die Evolutionsgeschichte
Curriculum vitae
| _ | _ |
|---|---|
| 1988 | MSc (Diploma), Zoology and Immunology, TU and LMU Munich, Germany |
| 1994 | PhD (Dr. rer.nat.), Inst. for Immunology, LMUniversity Munich, Germany |
| 1994-1998 | Postdoc Boehringer Ingelheim Fonds, UC Irvine and Caltech, USA |
| 1999-2012 | CNRS, Inst. for Developmental Biology Marseille (IBDM), France |
| 2008 | Habilitation in Developmental Biology, Univ. Aix-Marseille, France |
| 2012-2015 | Assistant Professor, Institute of Zoology, University Innsbruck, Austria |
| Since 2015 | Associate Professor, Institute of Zoology, University Innsbruck, Austria |
Publikationen 2024
Beiträge in Büchern / Zeitschriften
Zeitschriftenaufsatz (Originalarbeit)
Johnson, C. J.; Razy-Krajka, F.; Zeng, F.; Piekarz, K. M.; Biliya, S.; Rothbächer, U.; Stolfi, A (2024): Specification of distinct cell types in a sensory-adhesive organ important for metamorphosis in tunicate larvae.
In: PLoS Biology 22. (DOI)- Pennati, A.; Jakobi, M.; Zeng, F.; Ciampa, L.; Rothbächer, U. (2024): Optimizing CRISPR/Cas9 approaches in the polymorphic tunicate Ciona intestinalis.
In: Developmental Biology 510, S. 31 - 39. (DOI)
Sonstige Publikationen
elektronische Publikation (Preprint)
- Drago, L.; Pennati, A.; Rothbächer, U.; Ashita, R.; Hashimoto, S.; Saito, R.; Fujiwara, S.; Ballarin, L. (2024): Stress granule-related genes during embryogenesis of an invertebrate chordate. (Weblink)
- Pennati, Alessandro; Jakobi, Miloš; Zeng, Fan; Ciampa, Luca; Rothbaecher, Ute (2024): Optimizing Crispr/Cas9 Approaches in the Polymorphic Tunicate Ciona Intestinalis. (DOI) (Weblink)
Medienbeiträge
Beitrag in Zeitung
- Rothbächer, Ute: Molekulare Einblicke in die Evolutionsgeschichte.
In: Newsroom - www.uibk.ac.at vom 15.04.2024. (Weblink)
Publikationen 2023
Beiträge in Büchern / Zeitschriften
Zeitschriftenbeitrag (Proceedings Paper)
Rothbächer, U (2023): Ascidian gene regulation and bioadhesion.
In: Genesis 61/6, No. e23572. (DOI) (Weblink)
Sonstige Publikationen
elektronische Publikation (Preprint)
- Johnson, Christopher; Razy-Krajka, Florian; Zeng, Fan; Piekarz, Katarzyna; Biliya, Shweta; Rothbächer, Ute; Stolfi, Alberto (2023): Specification of distinct cell types in a sensory-adhesive organ for metamorphosis in the ciona larva.". (DOI) (Weblink)
Vorträge 2023
Präsentationen auf Kongressen, Tagungen o.Ä.
Vortrag bei Projektmeeting / Forschungskooperationstreffen
- Vortragende/r: Rothbächer, U.: Larval adhesion in tunicates.
Conference Bioadhesion & Adhesives, London, 14.12.2023. (Weblink)
Publikationen 2022
Beiträge in Büchern / Zeitschriften
Zeitschriftenaufsatz (Originalarbeit)
- Papadogiannis, V.; Pennati, A.; Parker, H.J.; Rothbächer, U.; Patthey, C.; Bronner, M.E.; Shimeld, S.M. (2022): Hmx gene conservation identifies the origin of vertebrate cranial ganglia.
In: Nature 605/7911, S. 701 - 705. (DOI) (Weblink)
Sammelbandaufsatz (Originalarbeit)
- Zeng, F.; Peronato, A.; Ballarin, L.; Rothbächer, U. (2022): Sweet Tunicate Blood Cells: A Glycan Profiling of Haemocytes in Three Ascidian Species.
In: Ballarin, L.; Rinkevich, B.; Hobmayer, B.: Advances in Aquatic Invertebrate Stem Cell Research: From Basic Research to Innovative Applications. Basel: MDPI AG., ISBN 978-3-0365-1636-3, S. 351 - 379. (DOI) (Weblink)
Medienbeiträge
Beitrag in Zeitung
- Rothbächer, U.; Pennati, A.: Wichtiger genetischer Ursprung unserer Sinne identifiziert (Interview).
In: wissenswert - Magazin der Universität Innsbruck vom 18.05.2022. (Weblink)
Vorträge 2022
Präsentationen auf Kongressen, Tagungen o.Ä.
Konferenzvortrag (auf Einreichung / Anmeldung)
- Vortragende/r: Pennati, A. Co-AutorInnen: Papadogiannis, V.; Parker, H.J.; Rothbächer, U.; Patthey, C.; Bronner, M.E.; Shimeld, S.M.: Hmx gene conservation identifies the origin of vertebrate cranial ganglia.
11th International Tunicate Meeting, Kobe, 14.07.2022. (Weblink) - Vortragende/r: Pennati, A. Co-AutorInnen: Rothbächer, U.: Hmx gene conservation identifies the origin of vertebrate cranial ganglia.
8th CMBI Meeting Innsbruck 2022, Igls, 30.09.2022. (Weblink)
Posterpräsentation
- Vortragende/r: Pennati, A. Co-AutorInnen: Rothbächer, U.: Hmx gene conservation identifies the origin of vertebrate cranial ganglia.
Life Science PhD Meeting 2022, Innsbruck, 21.04.2022. (Weblink)
Publikationen 2021
Beiträge in Büchern / Zeitschriften
Zeitschriftenaufsatz (Originalarbeit)
- Davey, P.A.; Power, A.M.; Santos, R.; Bertemes, P.; Ladurner, P.; Palmowski, P.; Clarke, J.; Flammang, P.; Lengerer, B.; Hennebert, E.; Rothbächer, U.; Pjeta, R.; Wunderer, J.; Zurovec, M.; Aldred, N. (2021): Omics-based molecular analyses of adhesion by aquatic invertebrates.
In: Biological Reviews 96/3, S. 1051 - 1075. (DOI) (Weblink)
Vorträge 2021
Präsentationen auf Kongressen, Tagungen o.Ä.
Konferenzvortrag (auf Einreichung / Anmeldung)
- Vortragende/r: Rothbächer, U.: Sweet tunicate blood cells: a glycan profiling of hemocytes in three ascidian species.
MARISTEM COST Action - Final Meeting, Padova, 20.10.2021. (Weblink) - Vortragende/r: Zeng, F. Co-AutorInnen: Rothbächer, U.: Bioadhesion in Ascidians.
4th International Conference on Biological and Biomimetic Adhesives, Aveiro, 19.02.2021. (Weblink)
Posterpräsentation
- Vortragende/r: Zeng, F. Co-AutorInnen: Rothbächer, U.: Cell types in the ascidian sensory adhesive organ focused on collocytes.
EMBO/EMBL Symposium: The Identity and Evolution of Cell Types, Heidelberg, 04.05.2021. (Weblink)
Publikationen 2020
Beiträge in Büchern / Zeitschriften
Zeitschriftenaufsatz (Originalarbeit)
- Imai, K.; Kobayashi, K.; Kari, W.; Rothbächer, U.; Ookubo, N.; Oda-Ishii, I.; Satou, Y. (2020): Gata is ubiquitously required for the earliest zygotic gene transcription in the ascidian embryo.
In: Developmental Biology 458/2, S. 215 - 227. (DOI) (Weblink) - Peronato, A.; Drago, L.; Rothbächer, U.; Macor, P.; Ballarin, L.; Nicola Franchi, N. (2020): Complement system and phagocytosis in a colonial protochordate.
In: Developmental & Comparative Immunology 103, No. 103530. (DOI) (Weblink)
Vorträge 2020
Gastvorträge
Gastvortrag
- Vortragende/r: Rothbächer, U.: Identifying adhesive components in tunicates.
Laboratoire de Biologie du Developpement de Villefranche-sur-mer (LBDV), Villefranche-sur-mer, 17.09.2020.
Publikationen 2019
Beiträge in Büchern / Zeitschriften
Zeitschriftenaufsatz (Originalarbeit)
- Zeng, F.; Wunderer, J.; Salvenmoser, W.; Ederth, T.; Rothbächer, U. (2019): Identifying adhesive components in a model tunicate.
In: Philosophical Transactions of The Royal Society B - Biological Sciences 374/1784, No. 20190197. (DOI) (Weblink) - Zeng, F.; Wunderer, J.; Salvenmoser, W.; Hess, M.W.; Ladurner, P.; Rothbächer, U. (2019): Papillae revisited and the nature of the adhesive secreting collocytes.
In: Developmental Biology 448/2, S. 183 - 198. (DOI) (Weblink)
Vorträge 2019
Präsentationen auf Kongressen, Tagungen o.Ä.
Konferenzvortrag (auf Einreichung / Anmeldung)
- Vortragende/r: Rothbächer, U.: Linking Ciona larval settlement to ageing.
FEBS Workshop "Ageing and Regeneration", Innsbruck, 11.09.2019. (Weblink) - Vortragende/r: Rothbächer, U.: Identifying adhesive components in a model tunicate.
Adhesion 2019: Fourteenth International Triennial Conference on the Science and Technology of Adhesion and Adhesives, Bristol, 03.09.2019. (Weblink) - Vortragende/r: Zeng, F. Co-AutorInnen: Rothbächer, U.: A fine analysis of the Ciona larval sensory adhesive organ.
10th International Tunicate Meeting, Villefranche-sur-mer, 11.07.2019. (Weblink)
Posterpräsentation
- Vortragende/r: Zeng, F. Co-AutorInnen: Rothbächer, U.: Linking Ciona larval settlement to ageing.
Life Science PhD Meeting Innsbruck 2019, Innsbruck, 26.04.2019. (Weblink)
Vorträge 2018
Präsentationen auf Kongressen, Tagungen o.Ä.
Konferenzvortrag (auf Einreichung / Anmeldung)
- Vortragende/r: Rothbächer, U.: Repression through Wnt signaling effectors.
7th Annual CMBI Meeting Innsbruck, Vill, 19.09.2018. (Weblink) - Vortragende/r: Rothbächer, U.: Repression of GATA binding sites by Wnt signaling effectors in the tunicate Ciona intestinalis.
IUBMB Focused Meeting on GATA Transcription Factors, Kreta, 28.05.2018. (Weblink)
Vortrag bei Projektmeeting / Forschungskooperationstreffen
- Vortragende/r: Rothbächer, U. Co-AutorInnen: Izumi, O.I.; Yutaka, S.; Willi, K.: Repression through Wnt signaling effectors.
European Wnt Meeting 2018, Heidelberg, 12.09.2018. (Weblink)
Posterpräsentation
- Vortragende/r: Rothbächer, U. Co-AutorInnen: Izumi, O.I.; Yutaka, S.; Willi, K.: Repression through Wnt signaling effectors.
European Wnt Meeting 2018, Heidelberg, 12.09.2018. (Weblink) - Vortragende/r: Zeng, F. Co-AutorInnen: Wunderer, J.; Salvenmoser, W.; Hess, M.W.; Ladurner, P.; Rothbächer, U.: Bioadhesion in the Ascidian Ciona intestinalis specially the adhesive secreting collocytes.
3rd International Conference on Biological and Biomimetic Adhesives (ICBBA 2018), Haifa, 20.11.2018. (Weblink) - Vortragende/r: Zeng, F. Co-AutorInnen: Wunderer, J.; Salvenmoser, W.; Hess, M.W.; Ladurner, P.; Rothbächer, U.: Bioadhesion in the Ascidian Ciona intestinalis and the adhesive secreting collocytes.
7th Annual CMBI Meeting Innsbruck, Vill, 19.09.2018. (Weblink)
Publikationen 2017
Sonstige Publikationen
elektronische Publikation (Preprint)
- Guéroult-Bellone, M.; Nitta, K.R.; Kari, W.; Jacox, E.; Beulé Dauzat, R.; Vincentelli, R.; Diarra, C.; Rothbächer, U.; Dantec, C.; Cambillau, C.; et al. (2017): Spacer sequences separating transcription factor binding motifs set enhancer quality and strength. (DOI) (Weblink)
Vorträge 2017
Präsentationen auf Kongressen, Tagungen o.Ä.
Konferenzvortrag (auf Einreichung / Anmeldung)
- Vortragende/r: Rothbächer, U.: Repression through Wnt signaling effectors.
9th International Tunicate Meeting, New York, 17.07.2017. (Weblink) - Vortragende/r: Rothbächer, U.: Bioadhesion in ascidians.
1st General Action Meeting Cost Action CA 15216, Wien, 06.03.2017. (Weblink)
Beitrag als Chairperson / SektionsleiterIn / DiskussionsleiterIn / DiskussionsteilnehmerIn
- Rothbächer, U.: Chair of Ecological Evolutionary Developmental Biology (ECO-EVO-DEVO).
Joint Meeting of the German and Japanese Societies of Developmental Biologists, Kiel, 15.03.2017. (Weblink)
Gastvorträge
Gastvortrag
- Vortragende/r: Rothbächer, U.: Evo-Devo of Ascidian Bioadhesion.
Università degli Studi di Padova / University of Padua / Universität Padua, Padova / Padua, 12.10.2017. (Weblink) - Vortragende/r: Rothbächer, U.: Ascidians as Evo-Devo model to study genetic mechanisms of cell fate choice.
Università degli Studi di Padova / University of Padua / Universität Padua, Padova / Padua, 11.10.2017. (Weblink)
Publikationen 2016
Beiträge in Büchern / Zeitschriften
Zeitschriftenaufsatz (Originalarbeit)
- Kari, W.; Zeng, F.; Zitzelsberger, L.; Will, J.P.; Rothbächer, U. (2016): Embryo Microinjection and Electroporation in the Chordate Ciona intestinalis.
In: Jove-Journal of Visualized Experiments 116, Nr. e54313. (Volltext) (DOI) (Weblink) - Oda-Ishii, I.; Kubo, A.; Kari, W.; Suzuki, N.; Rothbächer, U.; Satou, Y. (2016): A Maternal System Initiating the Zygotic Developmental Program through Combinatorial Repression in the Ascidian Embryo.
In: PLoS Genetics 12/5, Nr. e1006045. (DOI) (Weblink)
Vorträge 2016
Präsentationen auf Kongressen, Tagungen o.Ä.
Vortrag bei Projektmeeting / Forschungskooperationstreffen
- Vortragende/r: Rothbächer, U.: Larval adhesion in ascidians.
KONNECT Kick-Off Meeting, Potsdam, 17.11.2016.
Posterpräsentation
- Vortragende/r: Rothbächer, U. Co-AutorInnen: Gilchrist, M.J.G.; Lemaire, P.: A pipeline for the systematic identification of non-redundant full-ORF cDNAs for polymorphic and evolutionary divergent genomes: application to the ascidian Ciona intestinalis.
6th Meeting of the European Society for Evolutionary Developmental Biology, Uppsala, 26.07.2016. (Weblink) - Vortragende/r: Rothbächer, U. Co-AutorInnen: Kari, W.: TCF/ß-catenin mediated transcriptional repression in ascidians.
6th Meeting of the European Society for Evolutionary Developmental Biology, Uppsala, 26.07.2016. (Weblink) - Vortragende/r: Rothbächer, U. Co-AutorInnen: Zeng, F.; Wunderer, J.; Ladurner, P.: Bioadhesion in ascidians.
Symposium: Biological and Bioinspired Adhesion: From Macro- to Nanoscale, Potsdam, 27.09.2016. (Weblink) - Vortragende/r: Will, J.P. Co-AutorInnen: Rothbächer, U.: Mechanism of Ets factor repression during neural fate acquisition.
6th Annual CMBI Meeting Innsbruck, Gnadenwald, 03.03.2016. (Weblink) - Vortragende/r: Zeng, F. Co-AutorInnen: Wunderer, J.; Ladurner, P.; Rothbächer, U.: Bioadhesion in ascidians.
6th Annual CMBI Meeting Innsbruck, Gnadenwald, 03.03.2016. (Weblink)
Publikationen 2015
Beiträge in Büchern / Zeitschriften
Zeitschriftenaufsatz (Originalarbeit)
- Gilchrist, M.J.; Sobral, D.; Khoueiry, P.; Daian, F.; Laporte, B.; Patrushev, I.; Matsumoto, J.; Dewar, K.; Hastings, K.E.M.; Satou, Y.; Lemaire, P.; Rothbächer, U. (2015): A pipeline for the systematic identification of non-redundant full-ORF cDNAs for polymorphic and evolutionary divergent genomes: Application to the ascidian Ciona intestinalis.
In: Developmental Biology 404/2, S. 149 - 163. (DOI) (Weblink) - Murgan, S.; Kari, W.; Rothbächer, U.; Iché-Torres, M.; Mélénec, P.; Hobert, O.; Bertrand, V. (2015): Atypical transcriptional activation by TCF via a Zic transcription factor in C. elegans neuronal precursors.
In: Developmental Cell 33/6, S. 737 - 745. (DOI) (Weblink) - Pennati, R.; Rothbächer, U. (2015): Bioadhesion in ascidians: a developmental and functional genomics perspective.
In: Interface Focus 5/1, No. 20140061. (Volltext) (DOI) (Weblink)
Medienbeiträge
Beitrag in Zeitung
- Rothbächer, U.: Werkzeugkasten der Entwicklungsbiologie (Interview).
In: wissenswert - Magazin der Universität Innsbruck vom 17.02.2015. (Weblink)
Vorträge 2015
Präsentationen auf Kongressen, Tagungen o.Ä.
Konferenzvortrag (auf Einreichung / Anmeldung)
- Vortragende/r: Kari, W. Co-AutorInnen: Zitzelsberger, L.; Lemaire, P.; Rothbächer, U.: Atypical transcriptional switching via TCF/ß-catenin for germ layer segregation.
8th International Tunicate Meeting, Aomori, 15.07.2015. (Weblink)
Posterpräsentation
- Vortragende/r: Kari, W. Co-AutorInnen: Murgan, S.; Iché-Torres, M.; Mélénec, P.; Couillault, C.; Hobert, O.; Bertrand, V.; Rothbächer, U.: Alternative mechanism of TCF mediated transcriptional regulation.
Joint Meeting of the German and French Societies of Developmental Biologists, Nürnberg, 11.03.2015. (Weblink) - Vortragende/r: Kari, W. Co-AutorInnen: Zitzelsberger, L.; Bertrand, V.; Rothbächer, U.: Novel Mechanism of TCF Function in Ascidians.
7th Life Science Meeting Innsbruck 2015 and MCBO Science Day, Innsbruck, 27.02.2015. (Weblink) - Vortragende/r: Rothbächer, U. Co-AutorInnen: Sobral, D.; Khoueiry, P.; Daian, F.; Laporte, B.; Matsumoto, J.; Dewar, K.; Hastings, K.E.M.; Satou, Y.; Lemaire, P.; Gilchrist, M.J.: The Ciona intestinalis ORFeome, a GATEWAY clone collection.
Joint Meeting of the German and French Societies of Developmental Biologists, Nürnberg, 11.03.2015. (Weblink) - Vortragende/r: Wunderer, J. Co-AutorInnen: Pjeta, R.; Lengerer, B.; Rodrigues, M.; Salvenmoser, W.; Rothbächer, U.; Ladurner, P.: Learning from nature: biological adhesives and their technical and medical applications.
7th Life Science Meeting Innsbruck 2015 and MCBO Science Day, Innsbruck, 27.02.2015. (Weblink)
Vorträge 2014
Präsentationen auf Kongressen, Tagungen o.Ä.
Konferenzvortrag (auf Einreichung / Anmeldung)
- Vortragende/r: Rothbächer, U. Co-AutorInnen: Kari, W.; Zitzelsberger, L.; Bertrand, V.: Novel Mechanism of TCF Function in Ascidians.
6th Life Science Meeting Innsbruck 2014, Innsbruck, 25.09.2014. (Weblink)
Beitrag als Chairperson / SektionsleiterIn / DiskussionsleiterIn / DiskussionsteilnehmerIn
- Rothbächer, U.: Chair of Session 6: Signalling pathways II.
6th Life Science Meeting Innsbruck 2014, Innsbruck, 25.09.2014.
Posterpräsentation
- Vortragende/r: Kari, W. Co-AutorInnen: Rothbächer, U.: Novel mechanism of TCF function in Ciona intestinalis.
5th meeting of the European Society for Evolutionary Developmental Biology (EURO EVO DEVO 2014), Wien, 22.07.2014. (Weblink) - Vortragende/r: Kari, W. Co-AutorInnen: Rothbächer, U.; Zitzelsberger, L.; Bertrand, V.: Novel Mechanism of TCF Function in Ascidians.
6th Life Science Meeting Innsbruck 2014, Innsbruck, 25.09.2014. - Vortragende/r: Rothbächer, U.: Bioadhesion In Ascidians.
2nd International Conference on Biological and Biomimetic Adhesives (COST Action TD0906, Final meeting), Istanbul, 06.05.2014. (Weblink) - Vortragende/r: Wunderer, J. Co-AutorInnen: Lengerer, B.; Pjeta, R.; Rodrigues, M.; Carta, G.; Salvenmoser, W.; Arbore, R.; Berezikov, E.; Schärer, L.; Rothbächer, U.; Ladurner, P.: Exploring the adhesive system of Macrostomum lignano.
8th International Macrostomum Meeting, Basel, 28.11.2014. (Weblink) - Vortragende/r: Wunderer, J. Co-AutorInnen: Pjeta, R.; Lengerer, B.; Rodrigues, M.; Salvenmoser, W.; Rothbächer, U.; Ladurner, P.: Learning from nature: biological adhesives and their technical and medical applications.
6th Life Science Meeting Innsbruck 2014, Innsbruck, 25.09.2014.
Publikationen 2013
Sonstige Publikationen
elektronische Publikation, transferorientierte
- Rothbächer, U. (2013): Bericht zum „Phallusia Jamboree“, Montpellier, France; 28th-30th May 2013. (Weblink)
- Rothbächer, U. (2013): Bericht zum „4ème Seminaire EFOR“ (Network for Functional Studies in Model Organisms), 13.-14. Februar 2013, Paris, France. (Weblink)
Vorträge 2013
Präsentationen auf Kongressen, Tagungen o.Ä.
Konferenzvortrag (auf Einreichung / Anmeldung)
- Vortragende/r: Rothbächer, U. Co-AutorInnen: Gilchrist, M.J.; Sobral, D.; Khoueiry, P.; Daian, F.; Laporte, B.; Matsumoto, J.; Hastings, K.E.; Satou, Y.; Lemaire, P.: The Ciona intestinalis ORFeome, a GATEWAY clone collection.
7th International Tunicate Meeting, Neapel, 26.07.2013. (Weblink)
Posterpräsentation
- Vortragende/r: Kari, W. Co-AutorInnen: Bertrand, V.; Rothbächer, U.: Novel Mechanism of TCF-Function in Ciona intestinalis.
ÖAW Stipendienverleihung, Wien, 21.02.2013. (Weblink) - Vortragende/r: Kari, W. Co-AutorInnen: Zitzelsberger, L.; Lemaire, P.; Bertrand, V.; Rothbächer, U.: Novel mechanisms of TCF mediated transcriptional regulation in chordates.
5th ÖGMBT Annual Meeting / 5th Life Science Meeting of the Innsbruck Universities & Biophysics Austria, Innsbruck, 25.09.2013. (Weblink) - Vortragende/r: Kari, W. Co-AutorInnen: Zitzelsberger, L.; Rothbächer, U.: Ectodermal reprogramming in ascidians.
7th International Tunicate Meeting, Neapel, 22.07.2013. (Weblink)
Publikationen 2012
Beiträge in Büchern / Zeitschriften
Zeitschriftenaufsatz (Originalarbeit)
- Pasini, A.; Manenti, R.; Rothbächer, U.; Lemaire, P. (2012): Antagonizing retinoic acid and FGF/MAPK pathways control posterior body patterning in the invertebrate chordate Ciona intestinalis.
In: PLoS One 7/9, S. e46193. (DOI)
Book Chapter (Original Paper)
- Zeng, F.; Peronato, A.; Ballarin, L.; Rothbächer, U. (2022): Sweet Tunicate Blood Cells: A Glycan Profiling of Haemocytes in Three Ascidian Species. In: Ballarin, L.; Rinkevich, B.; Hobmayer, B.: Advances in Aquatic Invertebrate Stem Cell Research: From Basic Research to Innovative Applications. Basel: MDPI AG., ISBN 978-3-0365-1636-3, pp. 351 - 379. (Web link)
- Tassy, O., Dauga, D., Daian, F., Sobral, D., Robin, F., Khoueiry, P., Salgado, D., Fox, V., Caillol, D., Schiappa, R., Laporte, B., Rios, A., Luxardi, G., Kusakabe, T., Joly, J.S., Darras, S., Christiaen, L., Contensin, M., Auger, H., Lamy, C., Hudson, C., Rothbächer, U., Gilchrist, M.J., Makabe, K.W., Hotta, K., Fujiwara, S., Satoh, N., Satou, Y.and Lemaire, P. (2010). The ANISEED database: digital representation, formalization, and elucidation of a chordate developmental program. Genome Res 20, 1459-1468. doi:10.1101/gr.108175.110 (Web link)
- Khoueiry, P., Rothbächer, U., Ohtsuka, Y., Daian, F., Frangulian, E., Roure, A., Dubchak, I.and Lemaire, P. (2010). A cis-regulatory signature in ascidians and flies, independent of transcription factor binding sites. Curr Biol 20, 792-802. doi:10.1016/j.cub.2010.03.063
- Roure, A., Rothbächer, U., Robin, F., Kalmar, E., Ferone, G., Lamy, C., Missero, C., Mueller, F.and Lemaire, P. (2007). A multicassette Gateway vector set for high throughput and comparative analyses in ciona and vertebrate embryos. PLoS One 2, e916. doi:10.1371/journal.pone.0000916
- Rothbächer, U. , Bertrand, V., Lamy, C.and Lemaire, P. (2007). A combinatorial code of maternal GATA, Ets and beta-catenin-TCF transcription factors specifies and patterns the early ascidian ectoderm. Development 134, 4023-4032. doi:10.1242/dev.010850
- Pasini, A., Amiel, A., Rothbächer, U., Roure, A., Lemaire, P.and Darras, S. (2006). Formation of the ascidian epidermal sensory neurons: insights into the origin of the chordate peripheral nervous system. PLoS Biol 4, e225. doi:10.1371/journal.pbio.0040225
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