Members
Head
Research Department for Biomedical Aging Research
Personal webpage
Research area(s): cellular senescence in human dermal fibroblasts and vascular endothelial cells, reactive oxygen species, mitochondrial proteins as regulators of senescence, skin aging
Students: Elia Cappuccio, Michéle Petit, Andreas Andric
Alumni: Giorgia Baraldo, Sophia Wedel, Max Holzknecht, Ines Martic
Deputy Head
Department of Botany
Personal webpage
Research area(s): plant metabolomics, ageing of plant seeds, stress biology, lipid peroxidation
Student: Hooman Norouzi
Alumni: Davide Gerna, Nicki Marami-Zounouz
Deputy Head
Department of Molecular Biology
Personal webpage
Research area(s): stem cell biology, cellular reprogramming
Students: Amelie Schurer, Sofia Angelini
Alumni: Anita Erharter, Nikita Arnst, Marcel Tisch, Elisa Gabassi, Lena Böhnke, Julianne Beirute-Herrera
Faculty members
Research Department for Biomedical Aging Research
Personal webpage
Research area(s): regulation of B cell development and function, NF-kB signaling pathways, MiRNA-mediated post-transcriptional gene silencing
Student: Periklis Ziakis
Alumni: Magdalena Hagen (Co-supervisor)
Institute of Molecular Biology & Digital Science Center (DiSC)
Personal webpage
Research area(s):computational biology and bioinformatics, multi-omics data analysis, single-cell and spatial transcriptomics, immunity and cancer
Students: Irene Rigato, Lorenzo Merotto
Department of Zoology
Personal webpage
Research area(s):Regeneration, stem cells, ageing in the simple multicellular animal model Hydra, axial patterning, Wnt signaling
Alumni: Sabine Gufler, Moses Kibet
Department of Molecular Biology
Personal webpage
Research area(s): molecular mechanisms of vertebrate development, transcriptional control of pancreatic b-cell development
Students: Marc Sathianathan, Melanie Zott
Alumni: Onur Temocin
Department of Zoology
Personal webpage
Research area(s): developmental biology and evolution in the model organism tunicates/ascidians, molecular switches for gene regulation and cell fate acquisition, transcriptional repression mechanisms in Wnt/TCF/ß‑catenin and FGF/ERK/Ets signaling, functional genomics, bioadhesion
Alumni: Zeng Fang
Research Department for Biomedical Aging Research
Personal webpage
Reserach area(s): Immunosenescence, age-related changes of the T cell compartment, vaccination in old age
Student: Gabriel Knoll
Alumni: Magdalena Hagen
Research Department for Biomedical Aging Research
Personal webpage
Research area(s): mitochondrial proteins as regulators of cellular senescence, enzymology
Students: Max Holzknecht (Co-supervisor), Andreas Andric (Co-supervisor)
Research Department for Biomedical Aging Research
Personal webpage
Reserach area(s): Women's cancer (breast, ovarian, endometrial, and cervical cancer), risk prediction, screening, and early detection, BRCA1/2, DNA methylation signatures for the prediction of women's cancers (WID Tests), epigenetics, P4 Medicine
Alumni: Lena Schreiberhuber
Research Department for Biomedical Aging Research
Personal webpage
Research area(s): Biology of Adipose Stem Cells and Adipocytes, Cellular Aging, Obesity / Caloric Restriction
Students: Sonja Grossmann, Victoria Strobl
Institute of Molecular Biology
Personal webpage
Research area(s):pancreatic islet development, glucose metabolism, mechanisms of diabetic complications
Student: Pauline Bicker
Associated Faculty Members
Institute of Molecular Biology
Personal webpage
Research area(s):neurodevelopment, brain organoids, brain aging
Student: Beatriz Lopez-Amo Calvo (Co-supervisor)
Student Representative
Research Department for Biomedical Aging Research
Research area(s): Molecular cell biology
Thesis: Establishing FAHD1 as a novel druggable onco-target in human breast and prostate cancer
First supervisor: Priv.-Doz. Mag. Dr. Alexander K. H. Weiss
Department of Molecular Biology
Research area(s): Lysosomal storage disorders, stem cell biology, Neurodevelopmental modelling, neurodegeneration
Thesis: Stem cell-based disease modelling of Batten Disease using patient-specific iPSC-derived 2D and 3D models
First supervisor: Univ.-Prof. Dr. Frank Edenhofer
Department of Molecular Biology
Research area(s): Regeneration, Disease models, Metabolism
Thesis: Matrix Metalloproteinases (Mmps) in Diabetic Retinopathy
First supervisor: Assoc. Prof. Dr. Robin Kimmel
Research Department for Biomedical Aging Research
Research area(s): Mitochondrial physiology, aging, skin aging, cellular senescence
Thesis: Investigation of mitochondrial dysfunction and cellular senescence in different models and organisms
First supervisor: Univ.-Doz. Dr. Pidder Jansen-Dürr
Department of Pharmacy - Pharmaceutical Chemistry
Research area(s): cellular senescence, drug discovery, cancer
Thesis: Drug discovery across model systems: from breast cancer to senescent yeast
First supervisor: Univ.-Doz. Dr. Pidder Jansen-Dürr
Research Department for Biomedical Aging Research
Research area(s): Cell Metabolism and Differentiation Research
Thesis: Analysis of the weight loss target gene Insulin-response element binding protein-1 in white adipose tissue
First supervisor: Univ.-Prof. Dr. Werner Zwerschke
Research Department for Biomedical Aging Research
Research area(s): Immunosenescence and Vaccination
Thesis: Role and function of CD4+ and CD8+ regulatory cells in age and vaccination
First supervisor: Univ.-Prof. Dr. Birgit Weinberger
Department of Molecular Biology
Research area(s): Neurodevelopment, Aging, Regenerative Medicine, Biofabrication, Genetic Engineering and Molecular Biology
Thesis: Deciphering growth control in the developing and aged human brain
First supervisor: Univ.-Prof. Dr. Frank Edenhofer
Department of Molecular Biology
Research area(s): Computational bioogy, omics data analysis
Thesis: Computational reconstruction of cell trajectories from multi-omics data to advance regenerative medicine and cancer immunotherapy
First supervisor: Assoc. Prof. Francesca Finotello
Department of Botany
Research area(s): Plant Biochemistry and Metabolism; Plant Physiology
Thesis: Unravelling molecular mechanisms underlying the impact of the maternal environment on seed quality traits, with a special focus on seed longevity
First supervisor: Univ.-Prof. Dr. Ilse Kranner
Research Department for Biomedical Aging Research
Research area(s): Mitochondrial physiology, ageing, cellular senescence, cell proliferation, cancer
Thesis: Role of oxaloacetate decarboxylase FAHD1 in regulation of cell proliferation and cellular senescence
First supervisor: Univ.-Doz. Dr. Pidder Jansen-Dürr
Student Representative
Department of Molecular Biology
Research area(s): Computational biology, Omics data analysis
Thesis: Integrative analysis of multi-omics data to investigate molecular network rewiring in blood cancer
First supervisor: Assoc. Prof. Francesca Finotello
Department of Molecular Biology
Research area(s): Stem Cells, developmental biology
Thesis: The role of MNX1 in human pancreas development
First supervisor: Univ.-Prof. Dr. Dirk Meyer
Department of Molecular Biology
Research area(s): Neurodevelopment, Regenerative Medicine, Ageing, Stem Cell Biology
Thesis: Modelling Neurulation employing fetal neural stem cells
First supervisor: Univ.-Prof. Dr. Frank Edenhofer
Research Department for Biomedical Aging Research
Research area(s): Cell Metabolism and Differentiation Research
Thesis: Factors modulating extracellular matrix in adipose tissue
First supervisor: Univ.-Prof. Dr. Werner Zwerschke
Research Department for Biomedical Aging Research
Research area(s): Immunology, Molecular Biology
Thesis: Investigating the role of miR-142 locus during B cell development in young and old mice
First supervisor: Assoc. Prof. Dr. Emmanuel Derudder
Department of Molecular Biology
Research area(s): Developmental biology
Thesis: Molecular regulation of beta-cell fate determination and maintenance
First supervisor: Univ.-Prof. Dr. Dirk Meyer
Associated Member
Department of Botany
Research area(s): Plant biochemistry and metabolism
Thesis: Molecular Mechanisms of Ageing and Regeneration across different Kingdoms of Life
First supervisor: Univ.-Prof. Dr. Ilse Kranner
Research Department for Biomedical Aging Research
Research area(s): mitochondria, free radicals, senescence
Thesis: Role of mitochondria and free radicals in aging and signal transduction
First supervisor: Univ.-Doz. Dr. Pidder Jansen-Dürr
Department of Molecular Biology
Research area(s): neuroscience, stem Cell Biology and neurodevelopment
Thesis: TBA Characterization of human-specific cell cycle regulators in hNSCs using CRISPRi
First supervisor: Univ.-Prof. Dr. Frank Edenhofer
Department of Molecular Biology
Research area(s): Neuronal aging, Reprogramming of human fibroblasts into induced neurons (iN), Mild Cognitive Impairment (MCI), Transcriptome analysis, Alzheimer's Disease
Thesis: From normal aging to dementia: A patient-specific neuronal reprogramming approach for the progression of Mild Cognitive Impairment to Alzheimer's disease
First supervisor: Univ.-Prof. Dr. Frank Edenhofer (Co-supervisor: Jerome Mertens)
Department of Molecular Biology
Research area(s): Stem cell biology, regenerative medicine, neuroscience
Thesis: Establishment and application of human stem cell derived 3D in vitro brain models
First supervisor: Univ.-Prof. Dr. Frank Edenhofer
Department of Molecular Biology
Research area(s): Molecular Biology
Thesis: Age-induced organoid models for deciphering risk factors of Parkinson’s disease
First supervisor: Univ.-Prof. Dr. Frank Edenhofer
Department of Botany
Research area(s): Plant Biochemistry and Metabolism
Thesis: Interactions between hormones, antioxidants, and reactive oxygen species during seed germination
First supervisor: Univ.-Prof. Dr. Ilse Kranner
Department of Zoology
Research area(s): Evolutionary and developmental biology, regeneration
Thesis: WNT/β‑Catenin signaling in Hydra regeneration ‑ deciphering ancientgene regulatory mechanisms
First supervisor: Univ.-Prof Dr. Bert Hobmayer
Research Department for Biomedical Aging Research
Research area(s): Humoral Immunity
Thesis: Mir-142 – a key player in B cell development and function
First supervisor: Univ.-Prof. Dr. Birgit Weinberger
Research Department for Biomedical Aging Research
Research area(s): Molecular cell biology
Thesis: FAHD Proteins as potentailly druggable onco-targets
First supervisor: Univ.-Doz. Dr. Pidder Jansen-Dürr (Co-supervisor: Ass.-Prof. Mag. Dr. Alexander K. H. Weiss)
Department of Zoology
Research area(s): Evolutionary and developmental biology, regeneration
Thesis: Role of Myc associating factor x (Max) in Neoblast maintenance in flatworms
First supervisor: Univ.-Prof. Dr. Bert Hobmayer
Department of Molecular Biology
Research area(s): Neurodevelopment, Aging, Regenerative Medicine, Biofabrication, Genetic Engineering and Molecular Biology
Thesis: Deciphering growth control in the developing and aged human brain
First supervisor: Univ.-Prof. Dr. Frank Edenhofer
Research Department for Biomedical Aging Research
European Translational Oncology Prevention & Screenting (EUTOPS)
Research area(s): DNA methylation, gynecological cancers, molecular biology
Thesis: Epigenome-based risk prediction and detection of gynecological cancers
First supervisor: Univ.-Prof. Dr. Martin Widschwendter
Department of Molecular Biology
Research area(s): Stem Cells, developmental biology
Thesis: The role of MNX1 in human lineage determination
First supervisor: Univ.-Prof. Dr. Dirk Meyer
Department of Molecular Biology
Research area(s): Stem Cell biology, Neuroscience, Autism-Spectrum-Disorder
Thesis: Pathophysiological Effects of Autism-Spectrum-Disorder risk Mutations in Human Cell Culture Models
First supervisor: Univ.-Prof. Dr. Frank Edenhofer
Research Department for Biomedical Aging Research
Research area(s): Senescence, skin aging, molecular biology
Thesis: Using in vitro models to study extrinsic skin aging associated with air pollution and cigarette smoke to understand mechanisms of cellular senescene
First supervisor: Univ.-Doz. Dr. Pidder Jansen-Dürr
Department of Zoology
Research area(s): Bioadhesion research on Ascidian, Ciona intestinalis
Thesis: Bioadhesion in Ascidian
First supervisor: Assoc. Prof. Dr. Ute Rothbächer