Institute of Biochemistry

Contacts:
Institute of Biochemistry
University of Innsbruck
Peter-Mayr-Strasse 1a
A-6020 Innsbruck, Austria

Chair:
O.Univ.-Prof. Dr. Klaus Bister

Administrative Manager:
Gabriele Reiter

Origin of a human cancer gene traced back to the base of animal evolution.
Hartl M, Mitterstiller A, Valovka T, Breuker K, Hobmayer B, Bister K. Stem cell-specific activation of an ancestral myc protooncogene with conserved basic functions in the early metazoan Hydra. Proc. Natl. Acad. Sci. USA 107, Early Edition (Feb 8, 2010).
Inhibitor of cell transformation and potential tumor suppressor identified.
Hartl M, Nist A, Khan MI, Valovka T, Bister K. Inhibition of Myc-induced cell transformation by brain acid-soluble protein 1 (BASP1). Proc. Natl. Acad. Sci. USA 106, 5604-5609 (2009).