Institut für Pharmazie, AB Pharmakognosie

Publikationen 2023

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  Poulopoulou, Ioanna; Horgan, Mark James; Siewert, Bianka; Siller, Michaela; Palmieri, Luisa; Martinidou, Eftychia; Martens, Stefan; Fusani, Pietro; Temml, Veronika; Stuppner, Hermann; Gauly, Matthias (online first): In vitro evaluation of the effects of methanolic plant extracts on the embryonation rate of Ascaridia galli eggs.
  In: Veterinary Research Communications. (DOI) (Weblink)
  
  

Publikationen 2022

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  Heise, Niels; Friedrich, Sander; Temml, Veronika; Schuster, Daniela; Siewert, Bianka; Csuk, René (2022): N-methylated diazabicyclo[3.2.2]nonane substituted triterpenoic acids are excellent, hyperbolic and selective inhibitors for butyrylcholinesterase.
  In: European Journal of Medicinal Chemistry 227, No. 113947. (DOI) (Weblink)
  
  
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  Kretzer, C.; Jordan, P.M.; Meyer, K.; Hoff, D.; Werner, M.; Hofstetter, R.; Koeberle, A.; Helesbeux, J.; Stuppner, H.; Temml, V.; Schuster, D.; Werz, O. (2022): Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages.
  In: Biochemical Pharmacology 195, No. 114825. (DOI) (Weblink)
  
  

Zeitschriftenbeitrag (Meeting-Abstract)

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  Siewert, Bianka; Poulopoulou, Ionna; Horgan, Mark; Sigg, Ines; Martinidou, Luisa; Martens, Stefan; Fusani, Pietro; Gauly, Matthias; Jansen-Dürr, Pidder; Temml, Veronika; Stuppner, Hermann (2022): Herbs and Mountain Plants as an Alternative Medication for Anthelmintic Treatment in Livestock Species.
  In: Planta Medica 88/15, S. 1407. (DOI) (Weblink)
  
  

Beitrag in Proceedingsband (Abstract)

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  Horgan, Mark J.; Poulopoulou, Ioanna; Sigg, Ines; Siewert, Bianka; Siller, Michaela; Fusani, Pietro; Albertini, Eva; Temml, Veronika; Gauly, Matthias; Palmieri, Luisa; Martinidou, Eftychia; Martens, Stefan; Duerr, Pidder-Jansen; Stuppner, Hermann (2022): Anthelmintic activity of alpine cultivated Cicerbita alpina.
  In: Giuntini, F.: 3rd Annual CNPD Conference 2022 on ‘Natural Products and their role in post-Covid time’. Book of Abstracts & Programme. 2nd-4th March 2022, Liverpool, online. Liverpool: Liverpool John Moores University., S. 52. (Weblink)
  
  

Publikationen 2021

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  Mikayoulou, Miena; Mayr, Fabian; Temml, Veronika; Pandian, Arjun; Vermaak, Ilze; Chen, Weiyang; Komane, Baatile; Stuppner, Hermann; Viljoen, Alvaro (2021): Anti-tyrosinase activity of South African Aloe species and isolated compounds plicataloside and aloesin.
  In: Fitoterapia 150, Nr. 104828. (DOI) (Weblink)
  
  
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  Neukirch, Konstantin; Alsabil, Khaled; Dinh, Chau-Phi; Bilancia, Rossella; Raasch, Martin; Ville, Alexia; Cerqua, Ida; Viault, Guillaume; Breard, Dimitri; Pace, Simona; Temml, Veronika; Brunner, Elena; Jordan, Paul M.; Marques, Marta C.; Loeser, Konstantin; Gollowitzer, Andre; Permann, Stephan; Gerstmeier, Jana; Lorkowski, Stefan; Stuppner, Hermann; Garscha, Ulrike; Rodrigues, Tiago; Bernardes, Goncalo J. L.; Schuster, Daniela; Seraphin, Denis; Richomme, Pascal; Rossi, Antonietta; Mosig, Alexander S.; Roviezzo, Fiorentina; Werz, Oliver; Helesbeux, Jean-Jacques; Koeberle, Andreas (2021): Exploration of Long-Chain Vitamin E Metabolites for the Discovery of a Highly Potent, Orally Effective, and Metabolically Stable 5-LOX Inhibitor that Limits Inflammation.
  In: Journal of Medicinal Chemistry 64/15, S. 11496 - 11526. (DOI) (Weblink)
  
  
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  Tran, Thi Van Anh; Alilou, Mostafa; Zhigang, Rao; Pace, Simona; Schwaiger, Stefan; Kretzer, Christian; Temml, Veronika; Giesel, Carsten; Jordan, Paul M.; Bilancia, Rossella; Weinigel, Christina; Rummler, Silke; Waltenberger, Birgit; Hung, Tran; Rossi, Antonietta; Stuppner, Hermann; Werz, Oliver; Koeberle, Andreas (2021): From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution.
  In: Acta Pharmaceutica Sinica B 11/6, S. 1629 - 1647. (DOI) (Weblink)
  
  

Zeitschriftenbeitrag (Meeting-Abstract)

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  Horgan, Mark J; Poulopoulou, Ioanna; Sigg, Ines; Palmieri, Luisa; Martinidou, Eftychia; Martens, Stefan; Fusani, Pietro; Siewert, Bianka; Temml, Veronika; Albertini, Eva; Gauly, Matthias; Jansen-Dürr, Pidder; Stuppner, Hermann (2021): Alpine Sow-Thistle Against Nematodes: A Dual Approach to Anthelmintic Discovery.
  In: Planta Medica 87/15, S. 1260. (DOI)
  
  
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  Temml, Veronika; Huber-Cantonati, Petra; Mähr, Theresa; Schwitzer, Felix; Kretzer, Christian; Köberle, Andreas; Mayr, Fabian; Engels, Nora; Waltenberger, Birgit; Stuppner, Hermann; Werz, Oliver; Pachmayr, Johanna; Schuster, Daniela (2021): Benzylated dihydrochalcone MF-15 as a potent multitarget inhibitor of cancer cell growth.
  In: Planta Medica 87/15, S. 1301. (DOI) (Weblink)
  
  
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  Tran, Van Anh; Mostafa, Alilou; Rao, Zhigang; Pace, Simona; Schwaiger, Stefan; Kretzer, Christian; Temml, Veronika; Jordan, Paul; Rosella, Bilancia; Waltenberger, Birgit; Tran, Hung; Rossi, Antonietta; Stuppner, Hermann; Werz, Oliver; Koeberle, Andreas (2021): Switching from inflammation to resolution: what can we learn from medical plants?
  In: Planta Medica 87/15, S. 1242. (DOI) (Weblink)
  
  

Publikationen 2020

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  Dinh, C. P.; Ville, A.; Neukirch, K.; Viault, G.; Temml, V.; Koeberle, A.; Werz, O.; Schuster, D.; Stuppner, H.; Richomme, P.; Helesbeux, J.; Séraphin, D. (2020): Structure-based design, semi-synthesis and anti-inflammatory activity of tocotrienolic amides as 5-lipoxygenase inhibitors.
  In: European Journal of Medicinal Chemistry 202, No. 112518. (DOI) (Weblink)
  
  
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  KAFKA, M.; MAYR, F.; TEMML, V.; MÖLLER, G.; ADAMSKI, J.; HÖFER, J.; SCHWAIGER, S.; HEIDEGGER, I.; MATUSZCZAK, B.; SCHUSTER, D.; KLOCKER, H.; BEKTIC, J.; STUPPNER, H.; EDER, I.E. (2020): Dual Inhibitory Action of a Novel AKR1C3 Inhibitor on Both Full-Length AR and the Variant AR-V7 in Enzalutamide Resistant Metastatic Castration Resistant Prostate Cancer.
  In: Cancers 12/8, No. 2092. (DOI) (Weblink)
  
  
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  KRAMELL, A.E.; SIEWERT, B.; WIESE, J.; TEMML, V.; DEIGNER, H-P.; AL-HARRASI, A.; CSUK, R. (2020): The cytotoxicity of brazilin and derivatives might be due to an inhibition of the c-Src-kinase.
  In: Mediterranean Journal of Chemistry 10/8, S. 790 - 798. (DOI) (Weblink)
  
  
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  Mayr, F; Moller, G; Garscha, U; Fischer, J; Castano, PR; Inderbinen, SG; Temml, V; Waltenberger, B; Schwaiger, S; Hartmann, RW; Gege, C; Martens, S; Odermatt, A; Pandey, AV; Werz, O; Adamski, J; Stuppner, H; Schuster, D (2020): Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction.
  In: International Journal of Molecular Sciences 21/19, No. 7102. (DOI) (Weblink)
  
  
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  Murineddu, G; Asproni, B; Corona, P; Gessi, S; Merighi, S; Battistello, E; Sturaro, C; Calo, G; Galeotti, N; Temml, V; Herdlinger, S; Schuster, D; Pinna, GA (2020): Synthesis, biological evaluation and docking studies of a novel class of sulfur-bridged diazabicyclo[3.3.1]nonanes.
  In: Bioorganic Chemistry 102, No. 104072. (DOI) (Weblink)
  
  
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  Sisa, M; Dvorakova, M; Temml, V; Jarosova, V; Vanek, T; Landa, P (2020): Synthesis, inhibitory activity and in silico docking of dual COX/5-LOX inhibitors with quinone and resorcinol core.
  In: European Journal of Medicinal Chemistry 204, No. 112620. (DOI) (Weblink)
  
  

Publikationen 2019

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  AKRAM, M.; PATT, M.; KASERER, T.; TEMML, V.; WARATCHAREEYAKUL, W.; KRATSCHMAR, D.V.; HAUPENTHAL, J.; HARTMANN, R.W.; ODERMATT, A.; SCHUSTER, D. (2019): Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase.
  In: Journal of Steroid Biochemistry and Molecular Biology 192, No. 105358. (DOI) (Weblink)
  
  
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  DANZL, K.; MESSNER, B.; DOPPLER, C.; NEBERT, C.; ABFALTERER, A.; SAKIC, A.; TEMML, V.; HEINZ, K.; STREITWIESER, R.; EDELMANN, T.; MAIRHOFER, M.; GRIMM, M.; LAUFER, G.; ZIERER, A.; STUPPNER, H.; SCHUSTER, D.; PLONER, C.; MÜLLER, T.; BERNHARD, D. (2019): Early inhibition of endothelial retinoid uptake upon myocardial infarction restores cardiac function and prevents cell, tissue, and animal death.
  In: JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY 126, S. 105 - 117. (DOI) (Weblink)
  
  
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  GERSTMEIER, J.; SEEGERS, J.; WITT, F.; WALTENBERGER, B.; TEMML, V.; ROLLINGER, JM.; STUPPNER, H.; KOEBERLE, A.; SCHUSTER, D.; WERZ, O. (2019): Ginkgolic acid is a multi-target inhibitor of key enzymes in pro-inflammatory lipid mediator biosynthesis.
  In: Frontiers in Pharmacology 10, No. 797. (DOI) (Weblink)
  
  
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  Hosek, Jan; Lelakova, Veronika; Bobal, Pavel; Pizova, Hana; Gazdova, Marketa; Malanik, Milan; Jakubczyk, Karolina; Vesely, Ondrej; Landa, Premysl; Temml, Veronika; Schuster, Daniela; Prachyawarakorn, Vilailak; Pailee, Phanruethai; Ren, Gang; Zpurny, Filip; Oravec, Michal; Smejkal, Karel (2019): Prenylated Stilbenoids Affect Inflammation by Inhibiting the NF-kappa B/AP-1 Signaling Pathway and Cyclooxygenases and Lipoxygenase.
  In: Journal of Natural Products 82/7, S. 1839 - 1848. (DOI)
  
  
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  LELÀKOVÀ, V.; SMEJKAL, K.; JAKUBCZYK, K.; VESELÝ, O.; LANDA, P.; VÀCLAVÌK, J.; BOBÀL, P.; PÌZOVÀ, H.; TEMML, V.; STEINACHER, T.; SCHUSTER, D.; GRANICA, S.; HANÀKOVA, Z.; HOSEK, J. (2019): Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids.
  In: Food Chemistry 285, S. 431 - 440. (DOI) (Weblink)
  
  
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  Linhart, C; Niedrist, G.H.H; Nagler, M; Nagrani, R; Temml, V; Bardelli, T; Wilhalm, T; Riedl, A; Zaller, J.G; Clausing, P; Hertoge, K (2019): Pesticide contamination and associated risk factors at public playgrounds near intensively managed apple and wine orchards.
  In: Environmental Sciences Europe 31, No. 28. (Volltext) (DOI) (Weblink)
  
  
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  MURINEDDU, G.; GOTTI, C.; ASPRONIA, B.; CORONA, P.; MARTINELLO, K.; PLUTINO, S.; FUCILE, S.; TEMML, V.; MORETTI, M.; VIANI, P.; SCHUSTER, D.; PIRASA, S.; DELIGIA, F.; PINNA, G. (2019): Novel N-aryl nicotinamide derivatives: Taking stock on 3,6-diazabicyclo[3.1.1]heptanes as ligands for neuronal acetylcholine receptors.
  In: European Journal of Medicinal Chemistry 180, S. 51 - 61. (DOI) (Weblink)
  
  
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  TRAN, H.T.; GAO, X.; KRETSCHMER, N.; PFERSCHY-WENZIG, E.M.; RAAB, P.; PIRKER, T.; TEMML, V.; SCHUSTER, D.; KUNERT, O.; HUYNH, L.; BAUER, R. (2019): Anti-inflammatory and antiproliferative compounds from Sphaeranthus africanus.
  In: Phytomedicine 62, No. 152951. (DOI) (Weblink)
  
  
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  XI, D.; NIU, Y.; LI, H.; NOHA, S.M.; TEMML, V.; SCHUSTER, D.; WANG, C.; XU, F.; XU, P. (2019): Discovery of carbazole derivatives as novel allosteric MEK inhibitors by pharmacophore modeling and virtual screening.
  In: European Journal of Medicinal Chemistry 178, S. 802 - 817. (DOI) (Weblink)
  
  

Zeitschriftenbeitrag (anderer)

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  Vieider, Lisa; Romp, Erik; Temml, Veronika; Fischer, Jana; Kretzer, Christian; Schönthaler, Martin; Taha, Abdulla; Hernandez-Olmos, Victor; Sturm, Sonja; Schuster, Daniela; Werz, Oliver; Garscha, Ulrike; Matuszczak, Barbara (2019): Synthesis, Biological Evaluation and Structure–Activity Relationships of Diflapolin Analogues as Dual sEH/FLAP Inhibitors.
  In: ACS Medicinal Chemistry Letters 10/1, S. 62 - 66. (DOI) (Weblink)
  
  

Zeitschriftenbeitrag (Meeting-Abstract)

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  Temml, V.; Pein, H.; Pace, S.; Garscha, U.; Waltenberger, B.; Roviezzo, F.; Helesbeux, J.; Seraphin, D.; Rossi, A.; Lorkowski, S.; Richomme, P.; Werz, O.; Koeberle, A.; Schuster, D.; Stuppner, H. (2019): Computational Investigation of multi-target effects in the arachidonic acid cascade on the example of potent natural 5-LO inhibitor garcinoic acid.
  In: Planta Medica 85/18, S. 1524. (DOI) (Weblink)
  
  

Sammelbandaufsatz (Originalarbeit)

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  MAYR, F.; VIEIDER, C.; TEMML, V.; STUPPNER, H.; SCHUSTER, D. (2019): Open-Access Activity Prediction Tools for Natural Products. Case Study: hERG Blockers.
  In: Kinghorn, A.D.; Falk, H.; Gibbons, S.; Kobayashi, J.; Asakawa, Y.; Liu, J.-K.: Progress in the Chemistry of Organic Natural Products. Cheminformatics in Natural Product Research. Cham: Springer Nature (= Progress in the Chemistry of Organic Natural Products, 110)., ISBN 978-3-030-14631-3, S. 177 - 238. (DOI) (Weblink)
  
  

Publikationen 2018

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  Cheung, SY.; Werner, M.; Esposito, L.; Troisi, F.; Cantone, V.; Liening, S.; König, S.; Gerstmeier, J.; Koeberle, A.; Bilancia, R.; Rizza, R.; Rossi, A.; Roviezzo, F.; Temml, V.; Schuster, D.; Stuppner, H.; Schubert-Zsilavecz, M.; Werz, O.; Hanke, T.; Pace, S. (2018): Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation.
  In: European Journal of Medicinal Chemistry 156, S. 815 - 830. (DOI)
  
  
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  DREIER, D.; RESETAR, M.; TEMML, V.; RYCEK, L.; KRATENA, N.; SCHNÜRCH, M.; SCHUSTER, D.; DIRSCH, V.M.; MIHOVILOVIC, M.D. (2018): Magnolol dimer-derived fragments as PPARγ-selective probes.
  In: Organic & Biomolecular Chemistry 38/16, S. 7019 - 7028. (DOI) (Weblink)
  
  
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  PEIN, H.; VILLE, A.; PACE, S.; TEMML, V.; GARSCHA, U.; RAASCH, M.; ALSABIL, K.; VIAULT, G.; DINH, C.-P.; GUILET, D.; TROISI, F.; NEUKIRCH, K.; KÖNIG, S.; BILANCIA, R.; WALTENBERGER, B.; STUPPNER, H.; WALLERT, M.; LORKOWSKI, S.; WEINIGEL, C.; RUMMLER, S.; BIRRINGER, M.; ROVIEZZO, F.; SAUTEBIN, L.; HELESBEUX, J.-J.; SERAPHIN, D.; MOSIG, A.S.; SCHUSTER, D.; ROSSI, A.; RICHOMME, P.; WERZ, O.; KOEBERLE, A. (2018): Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.
  In: Nature Communications 9, No. 3834. (DOI)
  
  

Publikationen 2017

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  PEDUTO, A.; SCUOTTO, M.; KRAUTH, V.; ROVIEZZO, F.; ROSSI, A.; TEMML, V.; ESPOSITO, V.; STUPPNER, H.; SCHUSTER, D.; D´AGOSTINO, B.; SCHIRALDI, C.; DE ROSA, M.; WERZ, O.; FILOSA, R. (2017): Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase.
  In: European Journal of Medicinal Chemistry 127, S. 715 - 726. (DOI) (Weblink)
  
  
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  TEMML, V.; GARSCHA, U.; ROMP, E.; SCHUBERT, G.; GERSTMEIER, J.; KUTIL, Z.; MATUSZCZAK, B.; WALTENBERGER, B.; STUPPNER, H.; WERZ, O.; SCHUSTER, D. (2017): Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening.
  In: Scientific Reports 7, No. 42751. (DOI) (Weblink)
  
  
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  VUORINEN, A.; ENGELI, RT.; LEUGGER, S.; BACHMANN, F.; AKRAM, M.; ATANASOV, AG.; WALTENBERGER, B.; TEMML, V.; STUPPNER, H.; KRENN, L.; ATEBA, SB.; NJAMEN, D.; DAVIS, RA.; ODERMATT, A.; SCHUSTER, D. (2017): Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
  In: Journal of Natural Products 80/4, S. 965 - 974. (DOI)
  
  

Beitrag in Proceedingsband (Abstract)

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  TEMML, V.; GARSCHA, U.; ROMP, E.; SCHUBERT, G.; GERSTMEIER, J.; KUTIL, Z.; MATUSZCZAK, B.; WALTENBERGER, B.; STUPPNER, H.; WERZ, O.; SCHUSTER, D. (2017): Discovery of the first dual inhibitor of 5-lipoxygenase-activating protein and solulble epoxide hydrolase using pharmacophore-based virtual screening.
  In: Grasse, M.; Heinrichs, C. (Eds.): Abstract Book of the Life Science PhD Meeting, Innsbruck, 18.04. – 19.04.2017. Innsbruck: Eigenverlag - Universität Innsbruck / Innsbruck: Medizinische Universität Innsbruck., S. 79. (Weblink)
  
  
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  TEMML, V; GARSCHA, U.; ROMP, E.; SCHUBERT, G.; GERSTMEIER, J.; KUTIL, Z.; MATUSZCZAK, B.; WALTENBERGER, B.; STUPPNER, H.; WERZ, O.; SCHUSTER, D (2017): Discovery of the first dual inhibitor of 5-lipoxygenase-activating protein and solulble epoxide hydrolase using pharmacophore-based virtual screening.
  In: Stuppner, H.; Borchard, G.; Brenneisen, R.; Griesser, U.; Gstrein, E.: Book of Abstracts - Pharma2030 - Current and Future Challenges. A Joint Meeting of the Austrian Pharmaceutical Society (ÖPhG) and the Swiss Academy of Pharmaceutical Sciences (SAPhS), April 20-22, 2017. Innsbruck: Eigenverlag - Universität Innsbruck., S. 8.
  
  

Publikationen 2016

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  ALSABIL, K.; SUOR-CHERER, S.; KOEBERLE, A.; VIAULT, G.; LAVAUD, A.; TEMML, V.; WALTENBERGER, B.; SCHUSTER, D.; LITAUDON, M.; LORKOWSKI, S.; DE VAUMAS, R.; HELESBEUX, J-J.; GUILET, D.; STUPPNER, H.; WERZ, O.; SERAPHIN, D.; RICHOMME, P. (2016): Semisynthetic and Natural Garcinoic Acid Isoforms as New mPGES-1 Inhibitors.
  In: Planta Medica 82/11/12, S. 1110 - 1116. (DOI)
  
  
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  SCHAIBLE, A.M.; FILOSA, R.; KRAUTH, V.; TEMML, V.; PACE, S.; GARSCHA, U.; LIENING, S.; WEINIGEL, C.; RUMMLER, S.; SCHIEFERDECKER, S.; NETT, M.; PEDUTO, A.; COLLARILE, S.; SCUOTTO, M.; ROVIEZZO, F.; SPAZIANO, G.; DE ROSA, M.; STUPPNER, H.; SCHUSTER, D.; D´AGOSTINO, B.; WERZ, O. (2016): The 5-​lipoxygenase inhibitor RF-​22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo.
  In: Biochemical Pharmacology 112, S. 60 - 71. (DOI)
  
  
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  WALTENBERGER, B.; GARSCHA, U.; TEMML, V.; LIERS, J.; WERZ, O.; SCHUSTER, D.; STUPPNER, H. (2016): Discovery of Potent Soluble Epoxide Hydrolase (sEH) Inhibitors by Pharmacophore-Based Virtual Screening.
  In: Journal of Chemical Information and Modeling 56/4, S. 747 - 762. (DOI)
  
  
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  Zatelli, G.A.; Temml, V.; Kutil, Z.; Landa, P.; Vanek, T.; Schuster, D.; Falkenberg, M. (2016): Miconidin Acetate and Primin as Potent 5-Lipoxygenase Inhibitors from Brazilian Eugenia hiemalis (Myrtaceae).
  In: Planta Medica Letters 3/1, S. e17 - e19. (DOI) (Weblink)
  
  

Zeitschriftenbeitrag (Meeting-Abstract)

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  Sturm, S.; Gallmetzer, K.; Friedl, A.; Waltenberger, B.; Temml, V.; Stuppner, H. (2016): Laricifomes officinalis - a rich source of pharmacologically active triterpenes.
  In: Planta Medica 82/S1, S. P471. (DOI) (Weblink)
  
  

Beitrag in Proceedingsband (Abstract)

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  WALTENBERGER, B.; GARSCHA, U.; TEMML, V.; LIERS, J.; WERZ, O.; SCHUSTER, D.; STUPPNER, H. (2016): Pharmacophore modeling and virtual screening for the discovery of potent soluble Epoxide hydrolase (sEH) inhibitors.
  In: Hobmayer, Bert; Micura, Ronald; Striessnig, Jörg: Book of Abstracts - 6th CMBI Meeting. Gnadenwald, March 3-4, 2016. Innsbruck: Universität Innsbruck., S. 12. (Weblink)
  
  

Patente

Patent

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  Garscha, Ulrike; Kutil, Zsofia; Schuster, Daniela; Stuppner, Hermann; Temml, Veronika; Waltenberger, Birgit; Werz, Oliver (2016): N,n' -diarylurea, n,n' -diarylthiourea and n,n' -diarylguanidino compounds for use in treatment and prevention of inflammatory disease. 3 315 495 A1.
  
  

Publikationen 2015

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  Kaserer, T.; Temml, V.; Kutil, Z.; Vanek, T.; Landa, P.; Schuster, D. (2015): Prospective performance evaluation of selected common virtual screening tools. Case study: Cyclooxygenase (COX) 1 and 2.
  In: European Journal of Medicinal Chemistry 96, S. 445 - 457. (DOI) (Weblink)
  
  
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  Kutil, Z.; Kvasnicova, M.; Temml, V.; Schuster, D.; Marsik, P.; Cusimamani, E.F.; Lou, J.D.; Vanek, T.; Landa, P. (2015): Effect of Dietary Stilbenes on 5-Lipoxygenase and Cyclooxygenases Activities In Vitro.
  In: INTERNATIONAL JOURNAL OF FOOD PROPERTIES 18/7, S. 1471 - 1477. (DOI) (Weblink)
  
  
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  Kutil, Z.; Kvasnicova, M.; Temml, V.; Schuster, D.; Vanek, T.; Fernandez, E.; Malik, J.; Landa, P. (2015): The influence of the quinone antioxidants tert-butylhydroquinone and 2,5-di-tert-butylhydroquinone on the arachidonic acid metabolism in vitro.
  In: FOOD AND AGRICULTURAL IMMUNOLOGY 26/4, S. 504 - 511. (DOI) (Weblink)
  
  
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  SEEBACHER, W.; FAIST, J.; PRESSER, A.; WEIS, R.; SAF, R.; KASERER, T.; TEMML, V.; SCHUSTER, D.; ORTMANN, S.; OTTO, N.; BAUER, R. (2015): Synthesis of new 4-phenylpyrimidine-2(1H)-thiones and their potency to inhibit COX-1 and COX-2.
  In: European Journal of Medicinal Chemistry 101, S. 552 - 559. (DOI)
  
  

Zeitschriftenaufsatz (Review)

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  ATANASOV, A.G.; WALTENBERGER, B.; PFERSCHY-WENZIG, E.M.; LINDER, T.; WAWROSCH, C.; UHRIN, P.; TEMML, V.; WANG, L.; SCHWAIGER, S.; HEISS, E.H.; ROLLINGER, J.M.; SCHUSTER, D.; BREUSS, J.M.; BOCHKOV, V.; MIHOVILOVIC, M.D.; KOPP, B.; BAUER, R.; DIRSCH, V.M.; STUPPNER, H. (2015): Discovery and resupply of pharmacologically active plant-derived natural products: A review.
  In: Biotechnology Advances 33/8, S. 1582 - 1614. (DOI) (Weblink)
  
  

Zeitschriftenbeitrag (Meeting-Abstract)

• 
  ZATELLI, GA.; TEMML, V.; KUTIL, Z.; LANDA, P.; VANEK, T.; FALKENBERG, M.; SCHUSTER, D. (2015): Miconidin acetate, a natural 5-lipoxygenase (5-LOX) inhibitor from Eugenia hiemalis Camb. (Myrtaceae).
  In: Planta Medica 81/16, S. 1441. (DOI) (Weblink)
  
  

Publikationen 2014

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  Schaible, A. M.; Filosa, R.; Temml, V.; Krauth, V.; Matteis, M.; Peduto, A.; Bruno, F.; Luderer, S.; Roviezzo, F.; Di Mola, A.; de Rosa, M.; D'Agostino, B.; Weinigel, C.; Barz, D.; Koeberle, A.; Pergola, C.; Schuster, D.; Werz, O. (2014): Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.
  In: British Journal of Pharmacology 171/9, S. 2399 - 2412. (DOI)
  
  
• 
  Temml, Veronika; Voss, Constance V.; Dirsch, Verena M.; Schuster, Daniela (2014): Discovery of New Liver X Receptor Agonists by Pharmacophore Modeling and Shape-Based Virtual Screening.
  In: Journal of Chemical Information and Modeling 54/2, S. 367 - 371. (DOI)
  
  

Beitrag in Proceedingsband (Abstract)

• 
  KASERER, T.; TEMML, V.; KUTIL, Z.; MÜLLER, K.; ELMER, S.; GANZERA, M.; LANDA, P.; SCHUSTER, D. (2014): Performance evaluation of common virtual screening tools on selected representatives of different target classes.
  In: Book of Abstracts - 6th Life Science Meeting. Innsbruck: Eigenverlag - Universität Innsbruck., S. 19.
  
  
• 
  TEMML, V.; KASERER, T.; STEFANOVIC, I.; VON GRAFENSTEIN, S.; FUCHS, J.E.; LIEDL, K.R.; SCHUSTER, D. (2014): Natural products interacting with 5-lipoxygenase –but how and where?
  In: Book of Abstracts - International Symposium "Natural Products and Drug Discovery - Future Perspectives". Innsbruck: Eigenverlag - Universität Innsbruck.
  
  
• 
  WALTENBERGER, B.; LIERS, J.; TEMML, V.; GARSCHA, U.; WERZ, O.; SCHUSTER, D.; STUPPNER, H. (2014): Identification of potent soluble epoxide hydrolase (sEH) inhibitors by pharmacophore modeling and virtual screening.
  In: Book of Abstracts - 23rd Scientific Congress of the Austrian Pharmaceutical Society. Graz: Karl-Franzens Universität Graz., S. 33.
  
  
• 
  WALTENBERGER, B.; LIERS, J.; TEMML, V.; GARSCHA, U.; WERZ, O.; SCHUSTER, D.; STUPPNER, H. (2014): Pharmacophore Modeling and Virtual Screening for Soluble Epoxide Hydrolase (sEH) Inhibitors.
  In: Book of Abstracts - International Symposium "Natural Products and Drug Discovery - Future Perspectives". Innsbruck: Eigenverlag - Universität Innsbruck.
  
  

Publikationen 2013

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  Kuehnl, S.; Schroecksnadel, S.; Temml, V.; Gostner, J.M.; Schennach, H.; Schuster, D.; Schwaiger, S.; Rollinger, J.M.; Fuchs, D.; Stuppner, H. (2013): Lignans from Carthamus tinctorius suppress tryptophan breakdown via indoleamine 2,3-dioxygenase.
  In: Phytomedicine 20/13, S. 1190 - 1195. (DOI)
  
  
• 
  Temml, Veronika; Kuehnl, S.; Schuster, Daniela; Schwaiger, Stefan; Stuppner, Herrmann; Fuchs, D. (2013): Interaction of Carthamus tinctorius lignan arctigenin with the binding site of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase.
  In: FEBS Open Bio 3, S. 450 - 452. (DOI) (Weblink)
  
  

Beitrag in Proceedingsband (Abstract)

• 
  KASERER, T.; LAZIC, M.; TEMML, V.; SCHWAIGER, S.; STUPPNER, H.; SCHUSTER, D. (2013): Application of in silico profiling tools for the prediction and rationalization of natural product biological activities.
  In: Trends in natural products research: a young scientists meeting of PSE and ÖPhG. Book of Abstracts. Leicester: Phytochemical Society of Europe., ISBN 978-0-9565472-3-1, S. 33.
  
  
• 
  TEMML, V.; WINEKENSTÄDDE, D.; VOSS, C.; ROLLINGER, J. M.; STUPPNER, H.; DIRSCH, V.; SCHUSTER, D (2013): Identification of new LXR-ß modulators by in silico screening and biological evaluation.
  In: Trends in natural products research: a young scientists meeting of PSE and ÖPhG. Book of Abstracts. Leicester: Phytochemical Society of Europe., ISBN 978-0-9565472-3-1, S. 32.
  
  

Institut für Pharmazie, AB Pharmazeutische Chemie

Publikationen 2020

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  KAFKA, M.; MAYR, F.; TEMML, V.; MÖLLER, G.; ADAMSKI, J.; HÖFER, J.; SCHWAIGER, S.; HEIDEGGER, I.; MATUSZCZAK, B.; SCHUSTER, D.; KLOCKER, H.; BEKTIC, J.; STUPPNER, H.; EDER, I.E. (2020): Dual Inhibitory Action of a Novel AKR1C3 Inhibitor on Both Full-Length AR and the Variant AR-V7 in Enzalutamide Resistant Metastatic Castration Resistant Prostate Cancer.
  In: Cancers 12/8, No. 2092. (DOI) (Weblink)
  
  
• 
  Mayr, F; Moller, G; Garscha, U; Fischer, J; Castano, PR; Inderbinen, SG; Temml, V; Waltenberger, B; Schwaiger, S; Hartmann, RW; Gege, C; Martens, S; Odermatt, A; Pandey, AV; Werz, O; Adamski, J; Stuppner, H; Schuster, D (2020): Finding New Molecular Targets of Familiar Natural Products Using In Silico Target Prediction.
  In: International Journal of Molecular Sciences 21/19, No. 7102. (DOI) (Weblink)
  
  

Publikationen 2019

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  AKRAM, M.; PATT, M.; KASERER, T.; TEMML, V.; WARATCHAREEYAKUL, W.; KRATSCHMAR, D.V.; HAUPENTHAL, J.; HARTMANN, R.W.; ODERMATT, A.; SCHUSTER, D. (2019): Identification of the fungicide epoxiconazole by virtual screening and biological assessment as inhibitor of human 11β-hydroxylase and aldosterone synthase.
  In: Journal of Steroid Biochemistry and Molecular Biology 192, No. 105358. (DOI) (Weblink)
  
  
• 
  Hosek, Jan; Lelakova, Veronika; Bobal, Pavel; Pizova, Hana; Gazdova, Marketa; Malanik, Milan; Jakubczyk, Karolina; Vesely, Ondrej; Landa, Premysl; Temml, Veronika; Schuster, Daniela; Prachyawarakorn, Vilailak; Pailee, Phanruethai; Ren, Gang; Zpurny, Filip; Oravec, Michal; Smejkal, Karel (2019): Prenylated Stilbenoids Affect Inflammation by Inhibiting the NF-kappa B/AP-1 Signaling Pathway and Cyclooxygenases and Lipoxygenase.
  In: Journal of Natural Products 82/7, S. 1839 - 1848. (DOI)
  
  
• 
  LELÀKOVÀ, V.; SMEJKAL, K.; JAKUBCZYK, K.; VESELÝ, O.; LANDA, P.; VÀCLAVÌK, J.; BOBÀL, P.; PÌZOVÀ, H.; TEMML, V.; STEINACHER, T.; SCHUSTER, D.; GRANICA, S.; HANÀKOVA, Z.; HOSEK, J. (2019): Parallel in vitro and in silico investigations into anti-inflammatory effects of non-prenylated stilbenoids.
  In: Food Chemistry 285, S. 431 - 440. (DOI) (Weblink)
  
  

Zeitschriftenbeitrag (anderer)

• 
  Vieider, Lisa; Romp, Erik; Temml, Veronika; Fischer, Jana; Kretzer, Christian; Schönthaler, Martin; Taha, Abdulla; Hernandez-Olmos, Victor; Sturm, Sonja; Schuster, Daniela; Werz, Oliver; Garscha, Ulrike; Matuszczak, Barbara (2019): Synthesis, Biological Evaluation and Structure–Activity Relationships of Diflapolin Analogues as Dual sEH/FLAP Inhibitors.
  In: ACS Medicinal Chemistry Letters 10/1, S. 62 - 66. (DOI) (Weblink)
  
  

Sammelbandaufsatz (Originalarbeit)

• 
  MAYR, F.; VIEIDER, C.; TEMML, V.; STUPPNER, H.; SCHUSTER, D. (2019): Open-Access Activity Prediction Tools for Natural Products. Case Study: hERG Blockers.
  In: Kinghorn, A.D.; Falk, H.; Gibbons, S.; Kobayashi, J.; Asakawa, Y.; Liu, J.-K.: Progress in the Chemistry of Organic Natural Products. Cheminformatics in Natural Product Research. Cham: Springer Nature (= Progress in the Chemistry of Organic Natural Products, 110)., ISBN 978-3-030-14631-3, S. 177 - 238. (DOI) (Weblink)
  
  

Publikationen 2018

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  DREIER, D.; RESETAR, M.; TEMML, V.; RYCEK, L.; KRATENA, N.; SCHNÜRCH, M.; SCHUSTER, D.; DIRSCH, V.M.; MIHOVILOVIC, M.D. (2018): Magnolol dimer-derived fragments as PPARγ-selective probes.
  In: Organic & Biomolecular Chemistry 38/16, S. 7019 - 7028. (DOI) (Weblink)
  
  
• 
  PEIN, H.; VILLE, A.; PACE, S.; TEMML, V.; GARSCHA, U.; RAASCH, M.; ALSABIL, K.; VIAULT, G.; DINH, C.-P.; GUILET, D.; TROISI, F.; NEUKIRCH, K.; KÖNIG, S.; BILANCIA, R.; WALTENBERGER, B.; STUPPNER, H.; WALLERT, M.; LORKOWSKI, S.; WEINIGEL, C.; RUMMLER, S.; BIRRINGER, M.; ROVIEZZO, F.; SAUTEBIN, L.; HELESBEUX, J.-J.; SERAPHIN, D.; MOSIG, A.S.; SCHUSTER, D.; ROSSI, A.; RICHOMME, P.; WERZ, O.; KOEBERLE, A. (2018): Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase.
  In: Nature Communications 9, No. 3834. (DOI)
  
  

Publikationen 2017

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  Beck, K.R.; Bächler, M.; Vuorinen, A.; Wagner, S.; Akram, M.; Griesser, U.; Temml, V.; Klusonova, P.; Yamaguchi, H.; Schuster, D.; Odermatt, A. (2017): Inhibition of 11β-hydoxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole.
  In: Biochemical Pharmacology 130, S. 93 - 103. (DOI)
  
  
• 
  Garscha, U.; Romp, E.; Pace, S.; Rossi, A.; Temml, V.; Schuster, D.; König, S.; Gerstmeier, J.; Liening, S.; Werner, M.; Atze, H.; Wittmann, S.; Weinigel, C.; Rummler, S.; Scriba, G.K.; Sautebin, L.; Werz, O. (2017): Pharmacological profile and efficiency in vivo of diflapolin, the first dual inhibitor of 5-lipoxygenase-activating protein and soluble epoxide hydrolase.
  In: Scientific Reports 7, No. 9398. (DOI) (Weblink)
  
  
• 
  Hanáková, Z.; Hošek, J.; Kutil, Z.; Temml, V.; Landa, P.; Vanek, T.; Schuster, D.; Dall’Acqua, S.; Cvačka, J.; Polansky, O.; Šmejkal, K. (2017): Anti-inflammatory activity of natural geranylated flavonoids: cyclooxygenase and lipoxygenase inhibitory properties and proteomic analysis.
  In: Journal of Natural Products 80/4, S. 999 - 1006. (DOI) (Weblink)
  
  
• 
  PEDUTO, A.; SCUOTTO, M.; KRAUTH, V.; ROVIEZZO, F.; ROSSI, A.; TEMML, V.; ESPOSITO, V.; STUPPNER, H.; SCHUSTER, D.; D´AGOSTINO, B.; SCHIRALDI, C.; DE ROSA, M.; WERZ, O.; FILOSA, R. (2017): Optimization of benzoquinone and hydroquinone derivatives as potent inhibitors of human 5-lipoxygenase.
  In: European Journal of Medicinal Chemistry 127, S. 715 - 726. (DOI) (Weblink)
  
  
• 
  TEMML, V.; GARSCHA, U.; ROMP, E.; SCHUBERT, G.; GERSTMEIER, J.; KUTIL, Z.; MATUSZCZAK, B.; WALTENBERGER, B.; STUPPNER, H.; WERZ, O.; SCHUSTER, D. (2017): Discovery of the first dual inhibitor of the 5-lipoxygenase-activating protein and soluble epoxide hydrolase using pharmacophore-based virtual screening.
  In: Scientific Reports 7, No. 42751. (DOI) (Weblink)
  
  
• 
  VUORINEN, A.; ENGELI, RT.; LEUGGER, S.; BACHMANN, F.; AKRAM, M.; ATANASOV, AG.; WALTENBERGER, B.; TEMML, V.; STUPPNER, H.; KRENN, L.; ATEBA, SB.; NJAMEN, D.; DAVIS, RA.; ODERMATT, A.; SCHUSTER, D. (2017): Potential Antiosteoporotic Natural Product Lead Compounds That Inhibit 17β-Hydroxysteroid Dehydrogenase Type 2.
  In: Journal of Natural Products 80/4, S. 965 - 974. (DOI)
  
  

Beitrag in Proceedingsband (Abstract)

• 
  TEMML, V.; GARSCHA, U.; ROMP, E.; SCHUBERT, G.; GERSTMEIER, J.; KUTIL, Z.; MATUSZCZAK, B.; WALTENBERGER, B.; STUPPNER, H.; WERZ, O.; SCHUSTER, D. (2017): Discovery of the first dual inhibitor of 5-lipoxygenase-activating protein and solulble epoxide hydrolase using pharmacophore-based virtual screening.
  In: Grasse, M.; Heinrichs, C. (Eds.): Abstract Book of the Life Science PhD Meeting, Innsbruck, 18.04. – 19.04.2017. Innsbruck: Eigenverlag - Universität Innsbruck / Innsbruck: Medizinische Universität Innsbruck., S. 79. (Weblink)
  
  
• 
  TEMML, V; GARSCHA, U.; ROMP, E.; SCHUBERT, G.; GERSTMEIER, J.; KUTIL, Z.; MATUSZCZAK, B.; WALTENBERGER, B.; STUPPNER, H.; WERZ, O.; SCHUSTER, D (2017): Discovery of the first dual inhibitor of 5-lipoxygenase-activating protein and solulble epoxide hydrolase using pharmacophore-based virtual screening.
  In: Stuppner, H.; Borchard, G.; Brenneisen, R.; Griesser, U.; Gstrein, E.: Book of Abstracts - Pharma2030 - Current and Future Challenges. A Joint Meeting of the Austrian Pharmaceutical Society (ÖPhG) and the Swiss Academy of Pharmaceutical Sciences (SAPhS), April 20-22, 2017. Innsbruck: Eigenverlag - Universität Innsbruck., S. 8.
  
  

Publikationen 2016

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  ALSABIL, K.; SUOR-CHERER, S.; KOEBERLE, A.; VIAULT, G.; LAVAUD, A.; TEMML, V.; WALTENBERGER, B.; SCHUSTER, D.; LITAUDON, M.; LORKOWSKI, S.; DE VAUMAS, R.; HELESBEUX, J-J.; GUILET, D.; STUPPNER, H.; WERZ, O.; SERAPHIN, D.; RICHOMME, P. (2016): Semisynthetic and Natural Garcinoic Acid Isoforms as New mPGES-1 Inhibitors.
  In: Planta Medica 82/11/12, S. 1110 - 1116. (DOI)
  
  
• 
  SCHAIBLE, A.M.; FILOSA, R.; KRAUTH, V.; TEMML, V.; PACE, S.; GARSCHA, U.; LIENING, S.; WEINIGEL, C.; RUMMLER, S.; SCHIEFERDECKER, S.; NETT, M.; PEDUTO, A.; COLLARILE, S.; SCUOTTO, M.; ROVIEZZO, F.; SPAZIANO, G.; DE ROSA, M.; STUPPNER, H.; SCHUSTER, D.; D´AGOSTINO, B.; WERZ, O. (2016): The 5-​lipoxygenase inhibitor RF-​22c potently suppresses leukotriene biosynthesis in cellulo and blocks bronchoconstriction and inflammation in vivo.
  In: Biochemical Pharmacology 112, S. 60 - 71. (DOI)
  
  
• 
  WALTENBERGER, B.; GARSCHA, U.; TEMML, V.; LIERS, J.; WERZ, O.; SCHUSTER, D.; STUPPNER, H. (2016): Discovery of Potent Soluble Epoxide Hydrolase (sEH) Inhibitors by Pharmacophore-Based Virtual Screening.
  In: Journal of Chemical Information and Modeling 56/4, S. 747 - 762. (DOI)
  
  
• 
  Zatelli, G.A.; Temml, V.; Kutil, Z.; Landa, P.; Vanek, T.; Schuster, D.; Falkenberg, M. (2016): Miconidin Acetate and Primin as Potent 5-Lipoxygenase Inhibitors from Brazilian Eugenia hiemalis (Myrtaceae).
  In: Planta Medica Letters 3/1, S. e17 - e19. (DOI) (Weblink)
  
  

Beitrag in Proceedingsband (Abstract)

• 
  WALTENBERGER, B.; GARSCHA, U.; TEMML, V.; LIERS, J.; WERZ, O.; SCHUSTER, D.; STUPPNER, H. (2016): Pharmacophore modeling and virtual screening for the discovery of potent soluble Epoxide hydrolase (sEH) inhibitors.
  In: Hobmayer, Bert; Micura, Ronald; Striessnig, Jörg: Book of Abstracts - 6th CMBI Meeting. Gnadenwald, March 3-4, 2016. Innsbruck: Universität Innsbruck., S. 12. (Weblink)
  
  

Publikationen 2015

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  Kaserer, T.; Temml, V.; Kutil, Z.; Vanek, T.; Landa, P.; Schuster, D. (2015): Prospective performance evaluation of selected common virtual screening tools. Case study: Cyclooxygenase (COX) 1 and 2.
  In: European Journal of Medicinal Chemistry 96, S. 445 - 457. (DOI) (Weblink)
  
  
• 
  Kutil, Z.; Kvasnicova, M.; Temml, V.; Schuster, D.; Marsik, P.; Cusimamani, E.F.; Lou, J.D.; Vanek, T.; Landa, P. (2015): Effect of Dietary Stilbenes on 5-Lipoxygenase and Cyclooxygenases Activities In Vitro.
  In: INTERNATIONAL JOURNAL OF FOOD PROPERTIES 18/7, S. 1471 - 1477. (DOI) (Weblink)
  
  
• 
  Kutil, Z.; Kvasnicova, M.; Temml, V.; Schuster, D.; Vanek, T.; Fernandez, E.; Malik, J.; Landa, P. (2015): The influence of the quinone antioxidants tert-butylhydroquinone and 2,5-di-tert-butylhydroquinone on the arachidonic acid metabolism in vitro.
  In: FOOD AND AGRICULTURAL IMMUNOLOGY 26/4, S. 504 - 511. (DOI) (Weblink)
  
  
• 
  SEEBACHER, W.; FAIST, J.; PRESSER, A.; WEIS, R.; SAF, R.; KASERER, T.; TEMML, V.; SCHUSTER, D.; ORTMANN, S.; OTTO, N.; BAUER, R. (2015): Synthesis of new 4-phenylpyrimidine-2(1H)-thiones and their potency to inhibit COX-1 and COX-2.
  In: European Journal of Medicinal Chemistry 101, S. 552 - 559. (DOI)
  
  

Zeitschriftenaufsatz (Review)

• 
  ATANASOV, A.G.; WALTENBERGER, B.; PFERSCHY-WENZIG, E.M.; LINDER, T.; WAWROSCH, C.; UHRIN, P.; TEMML, V.; WANG, L.; SCHWAIGER, S.; HEISS, E.H.; ROLLINGER, J.M.; SCHUSTER, D.; BREUSS, J.M.; BOCHKOV, V.; MIHOVILOVIC, M.D.; KOPP, B.; BAUER, R.; DIRSCH, V.M.; STUPPNER, H. (2015): Discovery and resupply of pharmacologically active plant-derived natural products: A review.
  In: Biotechnology Advances 33/8, S. 1582 - 1614. (DOI) (Weblink)
  
  

Zeitschriftenbeitrag (Meeting-Abstract)

• 
  Koeberle, A.; Waltenberger, B.; Temml, V.; Schuster, D.; Sautebin, L.; Stuppner, H.; Richomme, P.; Werz, O. (2015): Vitamin E metabolites as potent inhibitors of 5-lipoxygenase.
  In: Naunyn-Schmiedeberg's Archives of Pharmacology 338/Supp. 1, S. 26. (DOI) (Weblink)
  
  
• 
  ZATELLI, GA.; TEMML, V.; KUTIL, Z.; LANDA, P.; VANEK, T.; FALKENBERG, M.; SCHUSTER, D. (2015): Miconidin acetate, a natural 5-lipoxygenase (5-LOX) inhibitor from Eugenia hiemalis Camb. (Myrtaceae).
  In: Planta Medica 81/16, S. 1441. (DOI) (Weblink)
  
  

Publikationen 2014

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  Kutil, Z.; Temml, V.; Maghradze, D.; Pribylova, M.; Dvorakova, M.; Schuster, D.; Vanek, T.; Landa, P. (2014): Impact of Wines and Wine Constituents on Cyclooxygenase-1, Cyclooxygenase-2, and 5-Lipoxygenase Catalytic Activity.
  In: Mediators of Inflammation 2014, ID 178931. (Weblink)
  
  
• 
  Schaible, A. M.; Filosa, R.; Temml, V.; Krauth, V.; Matteis, M.; Peduto, A.; Bruno, F.; Luderer, S.; Roviezzo, F.; Di Mola, A.; de Rosa, M.; D'Agostino, B.; Weinigel, C.; Barz, D.; Koeberle, A.; Pergola, C.; Schuster, D.; Werz, O. (2014): Elucidation of the molecular mechanism and the efficacy in vivo of a novel 1,4-benzoquinone that inhibits 5-lipoxygenase.
  In: British Journal of Pharmacology 171/9, S. 2399 - 2412. (DOI)
  
  
• 
  Temml, Veronika; Kaserer, Teresa; Kutil, Zsofia; Landa, Premysl; Vanek, Tomas; Schuster, Daniela (2014): Pharmacophore modeling for COX-1 and -2 inhibitors with LigandScout in comparison to Discovery Studio.
  In: Future Medicinal Chemistry 6/17, S. 1869 - 1881. (DOI) (Weblink)
  
  
• 
  Temml, Veronika; Voss, Constance V.; Dirsch, Verena M.; Schuster, Daniela (2014): Discovery of New Liver X Receptor Agonists by Pharmacophore Modeling and Shape-Based Virtual Screening.
  In: Journal of Chemical Information and Modeling 54/2, S. 367 - 371. (DOI)
  
  

Beitrag in Proceedingsband (Abstract)

• 
  KASERER, T.; TEMML, V.; KUTIL, Z.; MÜLLER, K.; ELMER, S.; GANZERA, M.; LANDA, P.; SCHUSTER, D. (2014): Performance evaluation of common virtual screening tools on selected representatives of different target classes.
  In: Book of Abstracts - 6th Life Science Meeting. Innsbruck: Eigenverlag - Universität Innsbruck., S. 19.
  
  
• 
  TEMML, V.; KASERER, T.; STEFANOVIC, I.; VON GRAFENSTEIN, S.; FUCHS, J.E.; LIEDL, K.R.; SCHUSTER, D. (2014): Natural products interacting with 5-lipoxygenase –but how and where?
  In: Book of Abstracts - International Symposium "Natural Products and Drug Discovery - Future Perspectives". Innsbruck: Eigenverlag - Universität Innsbruck.
  
  
• 
  WALTENBERGER, B.; LIERS, J.; TEMML, V.; GARSCHA, U.; WERZ, O.; SCHUSTER, D.; STUPPNER, H. (2014): Identification of potent soluble epoxide hydrolase (sEH) inhibitors by pharmacophore modeling and virtual screening.
  In: Book of Abstracts - 23rd Scientific Congress of the Austrian Pharmaceutical Society. Graz: Karl-Franzens Universität Graz., S. 33.
  
  
• 
  WALTENBERGER, B.; LIERS, J.; TEMML, V.; GARSCHA, U.; WERZ, O.; SCHUSTER, D.; STUPPNER, H. (2014): Pharmacophore Modeling and Virtual Screening for Soluble Epoxide Hydrolase (sEH) Inhibitors.
  In: Book of Abstracts - International Symposium "Natural Products and Drug Discovery - Future Perspectives". Innsbruck: Eigenverlag - Universität Innsbruck.
  
  

Publikationen 2013

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  Kuehnl, S.; Schroecksnadel, S.; Temml, V.; Gostner, J.M.; Schennach, H.; Schuster, D.; Schwaiger, S.; Rollinger, J.M.; Fuchs, D.; Stuppner, H. (2013): Lignans from Carthamus tinctorius suppress tryptophan breakdown via indoleamine 2,3-dioxygenase.
  In: Phytomedicine 20/13, S. 1190 - 1195. (DOI)
  
  
• 
  Landa, P.; Kutil, Z.; Temml, V.; Malik, J.; Kokoska, L.; Widowitz, U.; Pribylova, M.; Dvorakova, M.; Marsik, P.; Schuster, D.; Bauer, R.; Vanek, T. (2013): Inhibition of in vitro leukotriene B4 biosynthesis in human neutrophil granulocytes and docking studies of natural quinones.
  In: Natural Product Communications 8/1, S. 105 - 108. (Weblink)
  
  
• 
  Schaible, A. M.; Traber, H.; Temml, V.; Noha, S. M.; Filosa, R.; Peduto, A.; Weinigel, C.; Barz, D.; Schuster, D.; Werz, O. (2013): Potent inhibition of 5-lipoxygenase and liposomal prostaglandin E2 synthase-1 by the anti-carcinogenic and anti-inflammatory agent embelin.
  In: Biochemical Pharmacology 86/4, S. 476 - 486. (DOI) (Weblink)
  
  
• 
  Temml, Veronika; Kuehnl, S.; Schuster, Daniela; Schwaiger, Stefan; Stuppner, Herrmann; Fuchs, D. (2013): Interaction of Carthamus tinctorius lignan arctigenin with the binding site of tryptophan-degrading enzyme indoleamine 2,3-dioxygenase.
  In: FEBS Open Bio 3, S. 450 - 452. (DOI) (Weblink)
  
  

Beitrag in Proceedingsband (Abstract)

• 
  KASERER, T.; LAZIC, M.; TEMML, V.; SCHWAIGER, S.; STUPPNER, H.; SCHUSTER, D. (2013): Application of in silico profiling tools for the prediction and rationalization of natural product biological activities.
  In: Trends in natural products research: a young scientists meeting of PSE and ÖPhG. Book of Abstracts. Leicester: Phytochemical Society of Europe., ISBN 978-0-9565472-3-1, S. 33.
  
  
• 
  TEMML, V.; WINEKENSTÄDDE, D.; VOSS, C.; ROLLINGER, J. M.; STUPPNER, H.; DIRSCH, V.; SCHUSTER, D (2013): Identification of new LXR-ß modulators by in silico screening and biological evaluation.
  In: Trends in natural products research: a young scientists meeting of PSE and ÖPhG. Book of Abstracts. Leicester: Phytochemical Society of Europe., ISBN 978-0-9565472-3-1, S. 32.
  
  

Publikationen 2012

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

• 
  Landa, P.; Kutil, Z.; Temml, V.; Vuorinen, A.; Malik, J.; Dvorakova, M.; Marsik, P.; Kokoska, L.; Pribylova, M.; Schuster, D.; Vanek, T. (2012): Redox and Non-Redox Mechanism of In Vitro Cyclooxygenase Inhibition by Natural Quinones.
  In: Planta Medica 78/4, S. 326 - 333. (DOI)
  
  

Institut für Pharmazie, AB Pharmazeutische Technologie

Publikationen 2017

Beiträge in Büchern / Zeitschriften

Zeitschriftenaufsatz (Originalarbeit)

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  Beck, K.R.; Bächler, M.; Vuorinen, A.; Wagner, S.; Akram, M.; Griesser, U.; Temml, V.; Klusonova, P.; Yamaguchi, H.; Schuster, D.; Odermatt, A. (2017): Inhibition of 11β-hydoxysteroid dehydrogenase 2 by the fungicides itraconazole and posaconazole.
  In: Biochemical Pharmacology 130, S. 93 - 103. (DOI)