SFB-F44 - Cell signaling in chronic CNS disorders

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Project 11:
Identification of regulatory ncRNAs in chronic CNS disorders

Alexander Hüttenhofer

We aim to identify regulatory ncRNAs involved in neuronal development and chronic CNS disorders. Using special probes and techniques recently developed in our lab we aim to identify ncRNAs that are regulated in disease and may therefore contribute to signaling pathways involved in neurodegeneration. Similarly, we can use our expertise to to probe for regulatory ncRNAs participating in L-type Ca²⁺ channel -mediated plasticity and nuclear signaling in hippocampal neurons.