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SFB-F44 - Cell signaling in chronic CNS disorders

Other relevant publications of Jörg Striessnig

2013 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2000


Jörg Striessnig.
Lonely but diverse: Cav1.3 L-type Ca2+ channels in chochlear inner hair cells
Channels, 2013;


Rose RA, Sellan M, Simpson JA, Izaddoustdar F, Cifelli C, Panama BK, Davis M, Zhao D, Markhani M, Murphy GG, Striessnig J, Liu PP, Heximer SP, Backx PH (2011)
Iron-overload Decreases Cav1.3-dependent L-type Ca2+ Currents Leading to Bradycardia, Altered Electrical Conduction and Atrial Fibrillation.
Circ Arrhythm Electrophysiol. 2011 Jul 11. [Epub ahead of print]

Hirtz JJ, Boesen M, Braun N, Deitmer JW, Kramer F, Lohr C, Müller B, Nothwang HG, Striessnig J, Löhrke S, Friauf E. (2011)
Cav1.3 calcium channels are required for normal development of the auditory brainstem.
J Neurosci. 2011 Jun 1;31(22):8280-94.

Mahapatra S, Marcantoni A, Vandael DH, Striessnig J, Carbone E. (2011)
Are Cav 1.3 pacemaker channels in chromaffin cells? Possible bias from resting cell conditions and DHP blockers usage.
Channels (Austin). 2011 May 1;5(3):219-24. Epub 2011 May 1.

Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin HS, Isbrandt D, Ehmke H, Nargeot J, Mangoni ME (2011)
Functional roles of Cav 1.3, Cav 3.1 and HCN channels in automaticity of mouse atrioventricular cells: Insights into the atrioventricular pacemaker mechanism.
Channels (Austin). 2011 May 1;5(3):251-61. Epub 2011 May 1.

Marger L, Mesirca P, Alig J, Torrente A, Dubel S, Engeland B, Kanani S, Fontanaud P, Striessnig J, Shin HS, Isbrandt D, Ehmke H, Nargeot J, Mangoni ME (2011)
Pacemaker activity and ionic currents in mouse atrioventricular node cells.
Channels (Austin). 2011 May 1;5(3):241-50. Epub 2011 May 1.

Giordano TP, Tropea TF, Satpute SS, Sinnegger-Brauns MJ, Striessnig J, Kosofsky BE, Rajadhyaksha AM (2011)
Molecular switch from L-type Ca v 1.3 to Ca v 1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity.
J Neurosci. 2010 Dec 15;30(50):17051-62.


Baig SM, Koschak A, Lieb A, Gebhart M, Dafinger C, Nürnberg G, Ali A, Ahmad I, Sinnegger-Brauns MJ, Brandt N, Engel J, Mangoni ME, Farooq M, Khan HU, Nürnberg P, Striessnig J, Bolz HJ (2010)
Loss of Ca(v)1.3 (CACNA1D) function in a human channelopathy with bradycardia and congenital deafness.
Nat Neurosci. 2011 Jan;14(1):77-84. Epub 2010 Dec 5.

Müller CS, Haupt A, Bildl W, Schindler J, Knaus HG, Meissner M, Rammner B, Striessnig J, Flockerzi V, Fakler B, Schulte U (2010)
Quantitative proteomics of the Cav2 channel nano-environments in the mammalian brain.
Proc Natl Acad Sci (USA), 2010 Aug 24;107(34):14950-7. Epub 2010 Jul 28.

Marcantoni A, Vandael DH, Mahapatra S, Carabelli V, Sinnegger-Brauns MJ, Striessnig J, Carbone E. (2010)
Loss of Cav1.3 channels reveals the critical role of L-type and BK channel coupling in pacemaking mouse adrenal chromaffin cells.
J Neurosci. 2010 Jan 13;30(2):491-504.

Gebhart M, Juhasz-Vedres G, Zuccotti A, Brandt N, Engel J, Trockenbacher A, Kaur G, Obermair GJ, Knipper M, Koschak A, Striessnig J (2010)
Modulation of Cav1.3 Ca2+ channel gating by Rab3 interacting molecule.
Mol Cell Neurosci 44: 246-259

Striessnig J, Bolz HJ, Koschak A (2010)
Channelopathies in Cav1.1, Cav1.3, and Cav1.4 voltage-gated L-type Ca2+ channels.
Pflugers Arch 460: 361-374


Horak SB, Koschak A, Stuppner H, Striessnig J (2009)
Use-dependent block of voltage-gated Cav2.1 Ca2+ channels by petasins and eudesmol isomers.
J Pharmacol Exp Ther 330: 220-226

Bova S, Saponara S, Rampa A, Gobbi S, Cima L, Fusi F, Sgaragli G, Cavalli M, de Los Rios C, Striessnig J, Bisi A (2009)
Anthracene Based Compounds as New L-type Ca(2+) Channel Blockers: Design, Synthesis, and Full Biological Profile.
J Med Chem (in press, online)

Busquet P, Khoi Nguyen N, Schmid E, Tanimoto N, Seeliger MW, Ben-Yosef T, Mizuno F, Akopian A, Striessnig J, Singewald N (2009)
Cav1.3 L-type Ca2+ channels modulate depression-like behaviour in mice independent of deaf phenotype.
Int J Neuropsychopharmacol 13: 499-513

Subramanyam P, Obermair GJ, Baumgartner S, Gebhart M, Striessnig J, Kaufmann WA, Geley S, Flucher BE (2009)
Activity and calcium regulate nuclear targeting of the calcium channel 4b subunit in nerve and muscle cells.
Channels (Austin) 3: 343-55

Marcantoni A, Vandael DHF, Mahapatra S, Carabelli V, Sinnegger-Brauns MJ, Striessnig J, Carbone E (2009)
Loss of Cav1.3 channels reveals the critical role of L-type and BK-channel coupling in pacemaking mouse adrenal chromaffin cells.
J Neurosci 30:491-504

Striessnig J (2009)
An oily competition: role of -subunit palmitoylation for Ca2+ channel modulation by fatty acids.
J Gen Physiol 134: 363-367


Hendrich J, Van Minh AT, Heblich F, Nieto-Rostro M, Watschinger K, Striessnig J, Wratten J, Davies A, Dolphin AC (2008)
Pharmacological disruption of calcium channel trafficking by the 2 ligand gabapentin.
Proc Natl Acad Sci USA 105: 3628-3633

Mezghrani A, Monteil A, Watschinger K, Sinnegger-Brauns MJ, Barrere C, Bourinet E, Nargeot J, Striessnig J, Lory P (2008)
A destructive interaction mechanism accounts for dominant-negative effects of misfolded mutants of voltage-gated calcium channels.
J Neurosci 28:4501-11

Busquet P, Hetzenauer A, Sinnegger-Brauns MJ, Striessnig J, Singewald N (2008)
Role of L-type Ca channel isoforms in the extinction of conditioned fear.
Learn Mem 15:378-86

Singh A, Gebhart M, Fritsch R, Sinnegger-Brauns MJ, Poggiani C, Hoda JC, Engel J, Romanin C, Striessnig J, Koschak A (2008)
Modulation of voltage- and Ca2+-dependent gating of Cav1.3 L-type calcium channels by alternative splicing of a C-terminal regulatory domain.
J Biol Chem 283:20733-44.

Watschinger K, Horak SB, Schulze K, Obermair GJ, Wild C, Koschak A, Sinnegger-Brauns MJ, Tampe R, Striessnig J (2008)
Functional properties and modulation of extracellular epitope-tagged Cav2.1 voltage-gated calcium channels.
Channels (Austin) 2, 461-473

Sinnegger-Brauns MJ, Huber IG, Koschak A, Wild C, Obermair GJ, Einzinger U, Hoda JC, Sartori SB, Striessnig J (2008)
Expression and 1,4-dihydropyridine-binding properties of brain L-type calcium channel isoforms.
Mol Pharmacol, 75: 407-414

Striessnig J, Koschak A (2008)
Exploring the function and pharmacotherapeutic potential of voltage-gated Ca2+ channels with gene knockout models.
Channels (Austin) 2:233-251


Zhang J, Berra-Romani R, Sinnegger-Brauns MJ, Striessnig J, Blaustein MP, Matteson DR (2007)
Role of Cav1.2 L-type Ca2+ channels in vascular tone: effects of nifedipine and Mg2+.
Am J Physiol (Heart Circ Physiol) 292: H415-H425.

Erazo-Fischer E, Striessnig J, Taschenberger H (2007)
The role of physiological afferent nerve activity during in-vivo maturation of the calyx of Held synapse.
J Neurosci 27: 1725-1737

Koschak A, Obermair GJ, Pivotto F, Sinnegger-Brauns MJ, Striessnig J, Pietrobon D (2007)
Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.
J Neurosci, 27: 3855-3863

Wu J, Marmorstein AD, Striessnig J, Peachey NS (2007)
Voltage-dependent calcium channel Cav1.3 subunits regulate the light peak of the electroretinogram.
J Neurophysiol 97: 3731-3735.

Striessnig J (2007)
C-terminal tailoring of L-type calcium channel function.
J Physiol 585: 643-644

Navedo MF, Amberg GC, Westenbroek RE, Sinnegger-Brauns MJ, Catterall WA, Striessnig J, Santana LF (2007)
Cav1.3 channels produce persistent calcium sparklets, but Cav1.2 channels are responsible for sparklets in mouse arterial smooth muscle.
Am J Physiol (Heart Circ Physiol) 293: H1359-H1370


Striessnig J, Koschak A, Sinnegger-Brauns MJ, Hetzenauer A, Nguyen NK, Busquet P, Pelster G, Singewald N (2006)
Role of voltage-gated L-type Ca2+ channel isoforms for brain function.
Biochem Soc Trans 34:903-909

Hoda JC, Zaghetto F, Singh A, Koschak A, Striessnig J (2006)
Effects of congenital stationary night blindness type 2 mutations R508Q and L1364H on Cav1.4 L-type Ca2+ channel function and expression.
J Neurochem 96: 1648-58

Hetzenauer A, Sinnegger-Brauns MJ, Striessnig J, Singewald N (2006)
Brain activation pattern induced by stimulation of L-type Ca2+-channels: contribution of Cav1.3 and Cav1.2 isoforms.
Neuroscience 139: 1005-1015

Giordano TP 3rd, Satpute SS, Striessnig J, Kosofsky BE, Rajadhyaksha AM (2006)
Up-regulation of dopamine DL mRNA levels in the ventral tegmental area and dorsal striatum of amphetamine-sensitized C57BL/6 mice: role of Cav1.3 L-type Ca2+ channels.
J Neurochem 99:1197-1206

Singh A, Hamedinger D, Hoda JC, Gebhart M, Koschak A, Romanin C, Striessnig J (2006)
C-terminal modulator controls Ca2+ -dependent gating of Cav1.4 L-type Ca2+ channels.
Nat Neurosci 9: 1108-1116


Hoda JC, Zaghetto F, Koschak A, Striessnig J (2005)
CSNB2 mutations S229P, G369D, L1068P, and W1440X alter channel gating or functional expression of Cav1.4 L-type Ca2+ channels.
J Neurosci 25: 252-259

Wahanui AH, Berjukow S, Hope CI, Dearden PK, Wu S-B, Wilson-Wheeler J, Sharp DM, Treweek PL, Clover GM, Hoda J-C, Striessnig J, Marksteiner R, Hering S, Maw MA (2005)
A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation.
Proc Natl Acad Sci (USA) 102(21):7553-7558

Mangoni ME, Couette B, Marger L, Bourinet E, Striessnig J, Nargeot J (2005)
Voltage-dependent calcium channels and cardiac pacemaker activity: from ionic currents to genes.
Prog Biophys Mol Biol 90: 38-63

Catterall WA, Perez-Reyes E, Snutch TP, Striessnig J (2005)
International Union of Pharmacology XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.
Pharmacol Rev 57: 411-425

Striessnig J (2005)
Pathophysiology of migraine headache: Insight from pharmacology and genetics.
Drug Discovery Today 2: 453-462


Sinnegger-Brauns MJ, Hetzenauer A, Huber IG, Renström E, Wietzorrek G, Berjukov S, Cavalli M, Walter D, Koschak A, Waldschütz R, Hering S, Bova S, Rorsman P, Pongs O, Singewald S, Striessnig J (2004)
Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca2+ channels.
J Clin Invest 113: 1430-1439


Pietrobon D, Striessnig J (2003)
Neurobiology of migraine.
Nature Rev Neurosci 4: 386-398


Platzer J, Engel J, Schrott-Fischer A, Stephan K, Bova S, Chen H, Zheng H, Striessnig J (2000)
Congenital deafness and sinoatrial node dysfunction in mice lacking class D L-type Ca2+ channels.
Cell 102: 89-97