Date Title, Reference PDF 

Development, Mechanistic Elucidation, and Rational Optimization of a Tandem Ireland
Claisen/Cope Rearrangement Reaction for Rapid Access to the (Iso)Cyclocitrinol Core

C. W. Plummer, C. S. Wei, C. E. Yozwiak, A. Soheili, S. O. Smithback, J. L. Leighton, J. Am. Chem.
Soc. 2014, 136, 9878–9881.

p / k p / k

Total Synthesis of (–)-Xylogranatopyridine B via Palladium-Catalyzed Oxidative Stannlyation of Enones

A.W. Schuppe, D. Huang, Y. Chen, T. R. Newhouse, J. Am. Chem. Soc. 2018, 140, 2062–2066.

p / k p / k

Synthesis of Strophasterol A Guided by a Proposed Biosynthesis and Innate Reactivity

R. C. Heinze, D. Lentz, P. Heretsch, Angew. Chem. Int. Ed. 2016, 55, 11656–11659.

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Total Synthesis of (−)-Himalensine A

H. Shi, I. N. Michaelides, B. Darses, P. Jakubec, Q. N. N. Nguyen, R. S. Paton, D. J. Dixon, J. Am. Chem. Soc. 2017, 139, 17755–17758.

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Total Synthesis of (+)-Chinensiolide B

T. G. Elford, D. G. Hall, J. Am. Chem. Soc. 2010, 132, 1488–1489.

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Gram-Scale Enantioselective Formal Synthesis of Morphine

M. Tissot, R. J. Phipps, C. Lucas, R. M. Leon, R. D. M. Pace, T. Ngouansavanh, M. J. Gaunt
Angew. Chem. Int. Ed. 2014, 53, 13498–13501.

p / k p / k

Total Synthesis of Phomoidride D

J. C. Leung, A. A. Bedermann, J. T. Njardarson, D. A. Spiegel, G. K. Murphy, N. Hama, B. M. Twenter, P. Dong, T. Shirahata, I. M. McDonald, M. Inoue, N. Taniguchi, T. C. McMahon, C. M. Schneider, N. Tao, B. M. Stoltz, J. L. Wood, Angew. Chem. Int. Ed. 2018, 57, 1991–1994.

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Short, Enantioselective Total Synthesis of (+)-Chatancin

Y.-M. Zhao, T. J. Maimone, Angew. Chem. Int. Ed. 2015, 54, 1223–1226.

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A 11-Steps Total Synthesis of Magellanine through a Gold(I)-Catalyzed Dehydro Diels-Alder Reaction

P. McGee, G. Bétournay, F. Barabé, L. Barriault, Angew. Chem. Int. Ed. 2017, 56, 6280–6283.

p / k p / k

Total Syntheses of Dalesconol A and B

S. Snyder, T. Sherwood, A. Ross, Angew. Chem. Int. Ed. 2010, 49, 5146–5150.

p / k p / k

Total Synthesis of 4-Desmethyl-3alpha-hydroxy-15-rippertene

R. Henning, P. Metz, Angew. Chem. Int. Ed. 2009, 48, 1157–1159.

p / k p / k

Enantioselective Total Syntheses of Akuammiline Alkaloids (+)-Strictamine, (−)-2(S)-Cathafoline, and (−)-Aspidophylline A

J. Moreno, E. Picazo, L. A. Morrill, J. M. Smith, N. K. Garg, J. Am. Chem. Soc. 2016, 138, 1162–1165.

p / k p / k

Total Synthesis of Longeracinphyllin A

J. Li, W. Zhang, F. Zhang, Y. Chen, A. Li, J. Am. Chem. Soc. 2017, 139, 14893–14896.

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Total Synthesis of (−)-Mandelalide A Exploiting Anion Relay Chemistry (ARC)

M. H. Nguyen, M. Imanishi, T. Kurogi, and A. B. Smith, III,  J. Am. Chem. Soc. 2016, 138, 3675.

p / k p / k

Synthesis of the Paralytic Shellfish Poisons (+)-Gonyautoxin 2, (+)-Gonyautoxin 3 and (+)-11,11-Dihydroxysaxitoxin

J. V. Mulcahy, J. R. Walker, J. E. Merit, A. Whitehead, J. Du Bois, J. Am. Chem. Soc. 2016, 138, 5994−6001.

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Total Synthesis of (+)-Pleuromutilin

N. J. Fazakerley, M. D. Helm, D. J. Procter, Chem. Eur. J. 2013, 19, 6718–6723.

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Asymmetric Total Synthesis of ent-(−)-Roseophilin: Assignment of Absolute Configuration

D. L. Boger, J. Hong, J. Am. Chem. Soc. 2001, 123, 8515–8519.

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p / k

An Efficient Synthetic Approach to Cyanocycline A via [C+NC+CC] Coupling

Ü. Kaniskan, P. Garner, J. Am. Chem. Soc. 2007, 129, 15460–15461.

p / k p / k

Asymmetric Total Synthesis of Solandelactone E

A. Robinson, V. K. Aggarwal, Angew. Chem. Int. Ed. 2010, 49, 6673–6675.

p / k p / k

Total Synthesis of the Protein Phosphatase 2A Inhibitor Lactodehydrothyrsiferol

D. J. Clausen, S. Wan, P. E. Floreancing, Angew. Chem. Int. Ed. 2011, 50, 5178–5181.

p / k p / k

Enantioselective Total Synthesis of (+)-Psiguadial B

L. M. Chapman, J. C. Beck, L. Wu, S. E. Reisman, J. Am. Chem. Soc. 2016, 138, 9803–9806.

p / k p / k

Asymmetric Total Syntheses of Kopsia Indole Alkaloids

L. Leng, X. Zhou, Q. Liao, F. Wang, H. Song, D. Zhang, X. Liu, Y. Qin, Angew. Chem. Int. Ed. 2017, 56, 3703–3707.

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A Biomimetic Synthesis of (±)-Basiliolide B

X. Liang, L. Zhou, L. Min, W. Ye, W. Bao, W. Ma, Q. Yang, F. Qiao, X. Zhang, C.-S. Lee, Angew. Chem. Int. Ed. 2014, 53, 11294–11297.

p / k p / k

A Carbene Catalysis Strategy for the Synthesis of Protoilludane Natural Products: Total Synthesis of Armillaridin and Isovelleral

M. T. Hovey, D. T. Cohen, D. M. Walden, P. H.-Y. Cheong, K. A. Scheidt, Angew. Chem. Int. Ed. 2017, 56, 9864–9867.

p / k p / k

Total Synthesis of (−)-Dactylolide

S. Y. Yun, E. C. Hansen, I. Volchkov, E. J. Cho, W. Y. Lo, D. Lee, Angew. Chem. Int. Ed. 2010, 49, 4261–4263.

p / k p / k

Total Synthesis of (±)-spiramilactone B

H. Cheng, F.-H. Zeng, X. Yang, Y.-J. Meng, L. Xu, F.-P. Wang, Angew. Chem. Int. Ed. 2016, 55, 392–396.

p / k p / k

Biomimetic Total Synthesis of the Pentacyclic Amaryllidaceae Alkaloid Derivative Gracilamine

N. Y. Gao, M. G. Banwell, A. C. Willis, Org. Lett. 2017, 19, 162–165.

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Total Syntheses of Highly Oxidized ent-Kaurenoids Pharicin A, Pharicinin B, 7-O-Acetylpseurata C, and Pseurata C: A [5+2] Cascade Approach

C. He, J. Hu, Y. Wu, H. Ding, J. Am. Chem. Soc. 2017,139, 6098.

p / k p / k

Total synthesis of securinega alkaloids (−)-norsecurinine, (−)-niruroidine and (−)-flueggine A

N. Ma, Y. Yao, B.-X. Zhao, Y. Wang, W.-C. Ye, S. Jiang, Chem. Commun. 2014, 50, 9284–9287.

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Total Synthesis of (−)-Nakadomarin A

M. G. Nilson, R. L. Funk, Org. Lett. 2010, 12, 4912–4915.

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Total Synthesis of (−)-Histrionicotoxin through a Stereoselective Radical Translocation-Cyclization Reaction

M. Sato, H. Azuma, A. Daigaku, S. Sato, K. Takasu, K. Okano, H. Tokuyama, Angew. Chem. Int. Ed. 2017, 56, 1087–1091.

pk  p / k

A concise synthesis of (+)-batzelladine B from simple pyrrole-based starting materials

B. T. Parr, C. Economou, S. B. Herzon, Nature 2015, 525, 507–510.
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