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Publications

All articles

Peer-reviewed publications can be found on  PubMed.

 

Selected articles
 

  1. Sharifi S, Chaudhari P, Martirosyan A, Eberhardt AO, Witt F, Gollowitzer A, Lange L, Woitzat Y, Okoli EM, Li H, Rahnis N, Kirkpatrick J, Werz O, Ori A, Koeberle A, Bierhoff H, Ermolaeva M. (2024) Reducing the metabolic burden of rRNA synthesis promotes healthy longevity in Caenorhabditis elegans. Nat Commun, doi: 10.1038/s41467-024-46037-w.
  2. Su F, Koeberle A. (2023) Regulation and targeting of SREBP-1 in hepatocellular carcinoma. Cancer Metastasis Rev, doi: 10.1007/s10555-023-10156-5.
  3. Koeberle SC, Kipp AP, Stuppner H, Koeberle A. (2023) Ferroptosis-modulating small molecules for targeting drug-resistant cancer: Challenges and opportunities in manipulating redox signaling. Med Res Rev, doi: 10.1002/med.21933.
  4. Thürmer M, Gollowitzer A, Pein H, Neukirch K, Gelmez E, Waltl L, Wielsch N, Winkler R, Löser K, Grander J, Hotze M, Harder S, Döding A, Meßner M, Troisi F, Ardelt M, Schlüter H, Pachmayr J, Gutiérrez-Gutiérrez Ó, Rudolph KL, Thedieck K, Schulze-Späte U, González-Estévez C, Kosan C, Svatoš A, Kwiatkowski M, Koeberle A. (2022) PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling. Nat Commun, doi: 10.1038/s41467-022-30374-9.
  5. Neukirch K, Alsabil K, Dinh CP, Bilancia R, Raasch M, Ville A, Cerqua I, Viault G, Bréard D, Pace S, Temml V, Brunner E, Jordan PM, Marques MC, Loeser K, Gollowitzer A, Permann S, Gerstmeier J, Lorkowski S, Stuppner H, Garscha U, Rodrigues T, Bernardes GJL, Schuster D, Séraphin D, Richomme P, Rossi A, Mosig AS, Roviezzo F, Werz O, Helesbeux JJ, Koeberle A. (2021) Exploration of long-chain vitamin E metabolites for the discovery of a highly potent, orally effective and metabolically stable 5-LOX inhibitor that limits inflammation. J Med Chem, doi: 10.1021/acs.jmedchem.1c00806.
  6. Van Anh TT, Mostafa A, Rao Z, Pace S, Schwaiger S, Kretzer C, Temml V, Giesel C, Jordan PM, Bilancia R, Weinigel C, Rummler S, Waltenberger B, Hung T, Rossi A, Stuppner H, Werz O, Koeberle A (2021) From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution. Acta Pharm Sin B, doi: 10.1016/j.apsb.2021.04.011.
  7. Espada L, Dakhovnik A, Chaudhari P, Martirosyan A, Miek L, Poliezhaieva T, Schaub Y, Nair A, Doring N, Rahnis N, Werz O, Koeberle A, Kirkpatrick J, Ori A, Ermolaeva MA (2020) Loss of metabolic plasticity underlies metformin toxicity in aged Caenorhabditis elegans. Nat Metab, doi: 10.1038/s42255-020-00307-1.
  8. Pein H, Ville A, Pace S, Temml V, Garscha U, Raasch M, Alsabil K, Viault G, Dinh C, Guilet D, Troisi F, Neukirch K, König S, Waltenberger B, Stuppner H, Wallert M, Lorkowski S, Weinigel C, Rummler S, Birringer M, Sautebin L, Helesbeux JJ, Séraphin D, Mosig A, Schuster D, Rossi A, Richomme P, Werz O, Koeberle A. (2018) Endogenous metabolites of vitamin E limit inflammation by targeting 5-lipoxygenase. Nat Commun, doi: 10.1038/s41467-018-06158-5.
  9. Koeberle A, Shindou H, Koeberle SC, Laufer SA, Shimizu T, Werz O. (2013) Arachidonoyl-phosphatidylcholine oscillates during the cell cycle and counteracts proliferation by suppressing Akt membrane binding, Proc Natl Acad Sci U S A, doi: 10.1073/pnas.1216182110.
  10. Koeberle SC, Romir J, Fischer S, Koeberle A, Schattel V., Albrecht W., Grütter C, Werz O, Rauh D, Stehle T, Laufer S. (2011) Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor. Nat Chem Biol, doi: 10.1038/nchembio.761.
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