Clara Baldin, PhD

Postdoc

Institut für Mikrobiologie
Technikerstr. 25
A-6020 Innsbruck

Mikrobiologie I, Viktor-Franz-Hess Haus, 6. Stock, Zimmer 6/04

Tel.: +43 512 507-51254
Mail: clara.baldin@uibk.ac.at

Clara Baldin

Forschungsgebiete

  • Molecular cell biology of filamentous fungi
  • Fungal signal transduction
  • Plant-fungal interactions
  • Mycoparasitism and biocontrol
  • Protein expression

Publikationen

  • Sastré-Velásquez LE, Dallemulle A, Kühbacher A, Baldin C, Alcazar-Fuoli L, Niedrig A, Müller C, Gsaller F.  “The fungal expel of 5-fluorocytosine derived fluoropyrimidines mitigates its antifungal activity and generates a cytotoxic environment.” PLoS Pathog. 2022 Dec 27;18(12):e1011066. doi: 10.1371/journal.ppat.1011066
  • Baldin C, Kühbacher A, Merschak P, Wagener J, Gsaller F. “Modular Inducible Multigene Expression System for Filamentous Fungi.” Microbiol Spectr. 2022 Dec 21;10(6):e0367022. doi: 10.1128/spectrum.03670-22
  • López-Berges MS, Scheven MT, Hortschansky P, Misslinger M, Baldin C, Gsaller F, Werner ER, Krüger T, Kniemeyer O, Weber J, Brakhage AA, Haas H. “The bZIP Transcription Factor HapX Is Post-Translationally Regulated to Control Iron Homeostasis in Aspergillus fumigatus.” Int J Mol Sci. 2021 Jul 20;22(14):7739. doi: 10.3390/ijms22147739
  • Baldin C, Kühbacher A, Merschak P, Sastré-Velásquez LE, Abt B, Dietl AM, Haas H, Gsaller F. “Inducible Selectable Marker Genes to Improve Aspergillus fumigatus Genetic Manipulation.” J Fungi (Basel). 2021 Jun 24;7(7):506. doi: 10.3390/jof7070506
  • Soliman SSM, Baldin C, Gu Y, Singh S, Gebremariam T, Swidergall M, Alqarihi A, Youssef EG, Alkhazraji S, Pikoulas A, Perske C, Venkataramani V, Rich A, Bruno VM, Hotopp JD, Mantis NJ, Edwards JE Jr, Filler SG, Chamilos G, Vitetta ES, Ibrahim AS. “Mucoricin is a ricin-like toxin that is critical for the pathogenesis of mucormycosis.” Nat Microbiol. 2021 Mar;6(3):313-326. doi: 10.1038/s41564-020-00837-0
  • Andrianaki AM, Kyrmizi I, Thanopoulou K, Baldin C, Drakos E, Soliman SSM, Shetty AC, McCracken C, Akoumianaki T, Stylianou K, Ioannou P, Pontikoglou C, Papadaki HA, Tzardi M, Belle V, Etienne E, Beauvais A, Samonis G, Kontoyiannis DP, Andreakos E, Bruno VM, Ibrahim AS, Chamilos G. “Iron restriction inside macrophages regulates pulmonary host defense against Rhizopus species.” Nat Commun. 2018 Aug 20;9(1):3333. doi: 10.1038/s41467-018-05820-2
  • Baldin C, Soliman SSM, Jeon HH, Alkhazraji S, Gebremariam T, Gu Y, Bruno VM, Cornely OA, Leather HL, Sugrue MW, Wingard JR, Stevens DA, Edwards JE Jr, Ibrahim AS. “PCR-Based Approach Targeting Mucorales-Specific Gene Family for Diagnosis of Mucormycosis.” J Clin Microbiol. 2018 Sep 25;56(10):e00746-18. doi: 10.1128/JCM.00746-18
  • Baldin C, Ibrahim AS. “Molecular mechanisms of mucormycosis-The bitter and the sweet.” PLoS Pathog. 2017 Aug 3;13(8):e1006408. doi: 10.1371/journal.ppat.1006408
  • Gebremariam T, Alkhazraji S, Baldin C, Kovanda L, Wiederhold NP, Ibrahim AS. “Prophylaxis with Isavuconazole or Posaconazole Protects Immunosuppressed Mice from Pulmonary Mucormycosis.” Antimicrob Agents Chemother. 2017 Apr 24;61(5):e02589-16. doi: 10.1128/AAC.02589-16
  • Valiante V, Baldin C, Hortschansky P, Jain R, Thywißen A, Straßburger M, Shelest E, Heinekamp T, Brakhage AA. “The Aspergillus fumigatus conidial melanin production is regulated by the bifunctional bHLH DevR and MADS-box RlmA transcription factors.” Mol Microbiol. 2016 Oct;102(2):321-335. doi: 10.1111/mmi.13462
  • Altwasser R, Baldin C, Weber J, Guthke R, Kniemeyer O, Brakhage AA, Linde J, Valiante V. “Network Modeling Reveals Cross Talk of MAP Kinases during Adaptation to Caspofungin Stress in Aspergillus fumigatus.” PLoS One. 2015 Sep 10;10(9):e0136932. doi: 10.1371/journal.pone.0136932
  • Baldin C, Valiante V, Krüger T, Schafferer L, Haas H, Kniemeyer O, Brakhage AA. “Comparative proteomics of a tor inducible Aspergillus fumigatus mutant reveals involvement of the Tor kinase in iron regulation.” Proteomics. 2015 Jul;15(13):2230-43. doi: 10.1002/pmic.201400584
  • Perez-Nadales E, Nogueira MF, Baldin C, Castanheira S, El Ghalid M, Grund E, Lengeler K, Marchegiani E, Mehrotra PV, Moretti M, Naik V, Oses-Ruiz M, Oskarsson T, Schäfer K, Wasserstrom L, Brakhage AA, Gow NA, Kahmann R, Lebrun MH, Perez-Martin J, Di Pietro A, Talbot NJ, Toquin V, Walther A, Wendland J. “Fungal model systems and the elucidation of pathogenicity determinants.” Fungal Genet Biol. 2014 Sep;70(100):42-67. doi: 10.1016/j.fgb.2014.06.011
  • Müller S, Baldin C, Groth M, Guthke R, Kniemeyer O, Brakhage AA, Valiante V. “Comparison of transcriptome technologies in the pathogenic fungus Aspergillus fumigatus reveals novel insights into the genome and MpkA dependent gene expression.” BMC Genomics. 2012 Oct 2;13:519. doi: 10.1186/1471-2164-13-519
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