Publications since 2010

(see PubMed)

Hatzmann F.M., Großmann S., Waldegger P., Wiegers G.J., Mandl M., Rauchenwald T., Pierer G., Zwerschke W. Dipeptidyl peptidase-4 cell surface expression marks an abundant adipose stem/progenitor cell population with high stemness in human white adipose tissue. Adipocyte. 2022;11(1):601-615. doi: 10.1080/21623945.2022.2129060.

Mandl M., Viertler H.P., Hatzmann F.M., Brucker C., Großmann S., Waldegger P., Rauchenwald T., Mattesich M., Zwierzina M., Pierer G., Zwerschke W. An organoid model derived from human adipose stem/progenitor cells to study adipose tissue physiology. Adipocyte. 2022;11(1):164-174. doi: 10.1080/21623945.2022.2044601.

Mandl M, Viertler HP, Zopoglou M, Mitterberger-Vogt MC, Gasser J, Hatzmann FM, Rauchenwald T, Zwierzina ME, Mattesich M, Weiss AKH, Mottes L, Brucker C, Waldegger P, Pierer G, Zwerschke W. The circadian transcription factor ARNTL2 is regulated by weight-loss interventions in human white adipose tissue and inhibits adipogenesis. Cell Death Discov. 2022;8(1):443. doi: 10.1038/s41420-022-01239-3. 

Sailer S, Lackner K, Pras-Raves ML, Wever EJM, van Klinken JB, Dane AD, Geley S, Koch J, Golderer G, Werner-Felmayer G, Keller MA, Zwerschke W, Vaz FM, Werner ER, Watschinger K. Adaptations of the 3T3-L1 adipocyte lipidome to defective ether lipid catabolism upon Agmo knockdown. J Lipid Res. 2022 Jun;63(6):100222. doi: 10.1016/j.jlr.2022.100222.  

Klionsky,…, Zwerschke, W…, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 2021;17(1):1-382. doi: 10.1080/15548627.2020.1797280. 

Hatzmann FM, Ejaz A, Wiegers GJ, Mandl M, Brucker C, Lechner S, Rauchenwald T, Zwierzina M, Baumgarten S, Wagner S, Mattesich M, Waldegger P, Pierer G, Zwerschke W.  Quiescence, Stemness and Adipogenic Differentiation Capacity in Human DLK1^-/CD34⁺/CD24⁺ Adipose Stem/Progenitor. Cells. 2021 Jan 22;10(2):214; doi: 10.3390/cells10020214.

Cavinato M., Madreiter-Sokolowski C.T., Büttner S., Schosserer M., Zwerschke W., Wedel S., Grillari J., Graier W.F., Jansen-Dürr P. Targeting cellular senescence based on inter-organelle communication, multi-level proteostasis and metabolic control. FEBS J 2021;288(12):3834-3854. doi: 10.1111/febs.15631. 

Mandl M, Ritthammer H, Ejaz A, Wagner SA, Hatzmann FM, Baumgarten S, Viertler HP, Zwierzina ME, Mattesich M, Schiller V, Rauchenwald T, Ploner C, Waldegger P, Pierer G, Zwerschke W. CRISPR/Cas9-mediated gene knockout in human adipose stem/progenitor cells. Adipocyte. 2020 Dec;9(1):626-635. doi: 10.1080/21623945.2020.1834230.

 Zwerschke W. Editorial: Special issue cellular aging. Exp Gerontol. 2020;140:111065. doi: 10.1016/j.exger.2020.111065.  

Mandl M, Wagner SA, Hatzmann FM, Ejaz A, Ritthammer H, Baumgarten S, Viertler HP, Springer J, Zwierzina ME, Mattesich M, Brucker C, Waldegger P, Pierer G, Zwerschke W. Sprouty1 Prevents Cellular Senescence Maintaining Proliferation and Differentiation Capacity of Human Adipose Stem/Progenitor Cells. J Gerontol A Biol Sci Med Sci. 2020;75(12):2308-2319. doi: 10.1093/gerona/glaa098. 

Miggitsch C, Meryk A, Naismith E, Pangrazzi L, Ejaz A, Jenewein B, Wagner S, Nägele F, Fenkart G, Trieb K, Zwerschke W, Grubeck-Loebenstein B. Human bone marrow adipocytes display distinct immune regulatory properties. EBioMedicine. 2019;46:387-398. doi: 10.1016/j.ebiom.2019.07.023. 

Mandl M, Wagner SA, Hatzmann FM, Mitterberger-Voigt, MC, Zwierzina ME, Mattesich M, Zwerschke W. Sprouty1 is a weight-loss target gene in human adipose stem/progenitor cells that is mandatory for the initiation of adipogenesis. Cell Death Dis 2019;10(6):411. doi: 10.1038/s41419-019-1657-3.

Ejaz A, Hatzmann FM, Hammerle S, Ritthammer H, Mattesich M, Zwierzina M, Waldegger P and W Zwerschke. Fibroblast feeder layer supports adipogenic differentiation of human adipose stromal/progenitor cells. Adipocyte. 2019;8(1):178-189. doi: 10.1080/21623945.2019.1608751.

Krautgasser C., Mandl M., Hatzmann FM., Waldegger P., Mattesich M., Zwerschke W. Reliable reference genes for expression analysis of proliferating and adipogenically differentiating human adipose stromal cells. Cell Mol Biol Lett.2019 Feb 15;24:14. doi: 10.1186/s11658-019-0140-6.

Shi C., Uda Y., Dedic C., Azab E., Sun N., Hussein A.I., Petty CA., Fulzele K., Mitterberger-Vogt M.C., Zwerschke W., Pereira R., Wang K., Pajevic P.D. Carbonic anhydrase III protects osteocytes from oxidative stress. FASEB J. 2018 Jan;32(1):440-452. doi: 10.1096/fj.201700485RR.

Hörl S., Ejaz A., Ernst S., Mattesich M., Kaiser A., Jenewein B., Zwierzina M.E., Hammerle S., Miggitsch C., Mitterberger-Vogt M.C., Krautgasser C., Pierer G., Zwerschke W. CD146 (MCAM) in human cs-DLK1-/cs-CD34+ adipose stromal/progenitor cells. Stem Cell Research 2017;22:1-12. doi: 10.1016/j.scr.2017.05.004.

Ejaz A., Mattesich M., Zwerschke W. Silencing of the small GTPase DIRAS3 induces cellular senescence in human white adipose stromal/progenitor cells. Aging (Albany NY) 2017;9(3):860-879. doi: 10.18632/aging.101197.

Ejaz A., Mitterberger M.C., Lu Z., Mattesich M., Zwierzina M.E., Hörl S., Kaiser A., Viertler H.P., Rostek U., Meryk A., Khalid S., Pierer G., Bast R.C.Jr., Zwerschke W. Weight Loss Upregulates the Small GTPase DIRAS3 in Human White Adipose Progenitor Cells, Which Negatively Regulates Adipogenesis and Activates Autophagy via Akt-mTOR Inhibition. EBioMedicine 2016 Apr;6:149-161. doi: 10.1016/j.ebiom.2016.03.030.

Zwierzina M.E., Ejaz A., Bitsche M., Blumer M.J.F., Mitterberger M.C., Mattesich M. Amann A., Kaiser A., Pechriggl E.J., Hörl S., Rostek U., Pierer G., Fritsch H., Zwerschke W. Characterization of DLK1(PREF1)⁺/CD34⁺ cells in vascular stroma of human white adipose tissue. Stem Cell Res 2015;15(2):403-418. doi: 10.1016/j.scr.2015.08.004.

Zenzmaier C., Kern J., Heitz M., Plas E., Zwerschke W., Mattesich M., Sandner P., Berger P. Activators and stimulators of soluble guanylate cyclase counteract myofibroblast differentiation of prostatic and dermal stromal cells. Exp Cell Res 2015;338(2):162-169. doi: 10.1016/j.yexcr.2015.08.014.

Kaiser A., Jenewein B., Pircher H., Rostek U., Jansen-Dürr P., Zwerschke W. Analysis of human papillomavirus E7 protein status in C-33A cervical cancer cells. Virus Genes 2015;50(1):12-21. doi: 10.1007/s11262-014-1129-x.

Mitterberger M.C., Mattesich M., Zwerschke W. Bariatric surgery and diet-induced long-term caloric restriction protect subcutaneous adipose-derived stromal/progenitor cells and prolong their life span in formerly obese humans. Exp Gerontol 2014;56:106-113. doi: 10.1016/j.exger.2014.03.030.

Pauck A., Lener B., Hoell M., Kaiser A., Kaufmann A.M., Zwerschke W., Jansen-Dürr P. Depletion of the cdk inhibitor p16INK4a differentially affects proliferation of established cervical carcinoma cells. J Virol 2014;88(10):5256-5262. doi: 10.1128/JVI.03817-13.

Mitterberger M.C., Lechner S., Mattesch M. and Zwerschke W. Adipogenic differentiation is impaired in replicative senescent human subcutaneous adipose-derived stromal/progenitor cells. J Gerontol A Biol Sci Med Sci 2014;69(1):13-24. doi: 10.1093/gerona/glt043.

Mitterberger M.C., Zwerschke W. Mechanisms of Resveratrol-Induced Inhibition of Clonal Expansion and Terminal Adipogenic Differentiation in 3T3-L1 Preadipocytes. J Gerontol A Biol Sci Med Sci 2013;68(11):1356-1376. doi: 10.1093/gerona/glt019.

Lechner S., Mitterberger M.C., Mattesich M., Zwerschke W. Role of C/EBPβ-LAP and C/EBPβ-LIP in early adipogenic differentiation of human white adipose-derived progenitors and at later stages in immature adipocytes. Differentiation 2013;85(1-2):20-31. doi: 10.1016/j.diff.2012.11.001.

Mitterberger M.C., Kim G., Rostek U., Levine R.L., Zwerschke W. Carbonic anhydrase III regulates peroxisome proliferator-activated receptor-γ2. Exp Cell Res 2012;318(8):877-886. doi: 10.1016/j.yexcr.2012.02.011.

Mitterberger M.C., Lechner S., Mattesich M., Kaiser A., Probst D., Wenger N., Pierer G., Zwerschke W. DLK1(PREF1) is a negative regulator of adipogenesis in CD105+/CD90+/CD34+/CD31-/FABP4- adipose-derived stem cells from subcutaneous abdominal fat pats of adult women. Stem Cell Res 2012;9(1):35-48. doi: 10.1016/j.scr.2012.04.001.

Morandell D., Kaiser A., Herold S., Rostek U., Lechner S., Mitterberger M.C., Jansen-Dürr P., Eilers M., Zwerschke W. The human papillomavirus type 16 E7 oncoprotein targets Myc-interacting zinc-finger protein-1. Virology 2012;422(2):242-253. doi: 10.1016/j.virol.2011.10.027.

Ehehalt D., Lener B., Pircher H., Dreier K., Pfister H., Kaufmann A.M., Frangini S., Ressler S., Müller-Holzner E., Schmitt M., Höfler D., Rostek U., Kaiser A., Widschwendter A., Zwerschke W., Jansen-Dürr P. Detection of human papillomavirus type 18 E7 oncoprotein in cervical smears: a feasibility study. J Clin Microbiol 2012;50(2):246-257. doi: 10.1128/JCM.01108-11.

Micutkova L., Hermann M., Offterdinger M., Hess M.W., Matscheski A., Pircher H., Mück C., Ebner H.L., Laich A., Ferrando-May E., Zwerschke W., Huber L.A., Jansen-Dürr P. Analysis of the cellular uptake and nuclear delivery of Insulin-like Growth Factor Binding Protein-3 in human osteosarcoma cells. Int J Cancer 2012;130(7):1544-1557. doi: 10.1002/ijc.26149.

Mitterberger M.C., Mattesich M., Klaver E., Piza-Katzer H., Zwerschke W. Reduced insulin-like growth factor-I serum levels in formerly obese women subjected to laparoscopic-adjustable gastric banding or diet-induced long-term caloric restriction. J Gerontol A Biol Sci Med Sci 2011;66(11):1169-77. doi: 10.1093/gerona/glr149.

Dreier K., Scheiden R., Lener B., Ehehalt D., Pircher H., Müller-Holzner E., Rostek U., Kaiser A., Fiedler M., Ressler S., Lechner S., Widschwendter A., Even J., Capesius C., Jansen-Dürr P., Zwerschke W. Subcellular localization of the human papillomavirus 16 E7 oncoprotein in CaSki cells and its detection in cervical adenocarcinoma and adenocarcinoma in situ. Virology 2011;409(1):54-68. doi: 10.1016/j.virol.2010.09.024.

Pircher H., Matscheski A., Laich A., Hermann M., Moser B., Viertler H.P., Micutkova L., Lindner H., Sarg B., Zwerschke W., Jansen-Dürr P. A new method for the purification of bioactive insulin-like growth factor-binding protein-3. Protein Expr Purif 2010;71(2):160-167. doi: 10.1016/j.pep.2010.02.005.

 Mitterberger M.C., Mattesich M., Klaver E., Lechner S., Engelhardt T., Larcher L., Pierer G., Piza-Katzer H., Zwerschke W. Adipokine profile and insulin sensitivity in formerly obese women subjected to bariatric surgery or diet-induced long-term caloric restriction. J Gerontol A Biol Sci Med Sci 2010;65(9):915-923. doi: 10.1093/gerona/glq107.