Curriculum Vitae

Günter LEPPERDINGER                 Univ. DDoz. Dr. Mag. rer. nat.
University Innsbruck, Institute of Aging Research, Rennweg 10 
A-6020 Innsbruck, Austria; guenter.lepperdinger@uibk.ac.at
DOB: August 16th, 1966 - POB: Salzburg, AUSTRIA
Austrian, married, 3 children
ACADEMIC APPOINTMENTS and POSITIONS: 
2004: tenure (section head and PI at the Institute for Aging Research) 
2004: venia docendi/appointed professor: University of Innsbruck, Developmental Biology
2002-: Austrian Academy of Sciences, Innsbruck Austria Biomedical Aging Research
2001-02: National Institutes of Health, Bethesda, MD Developmental Biology, Transgenics
2000: venia docendi/appointed professor: University of Salzburg, Biochemisty
1998-99: Max Planck-Institute of Biochemistry, Department of Protein Chemistry
1994-2000: Institute of Molecular Biology Austrian Acad. Sci., Salzburg
1994-1999: lector: at the General Hospital, Salzburg, Chemistry and Biochemistry
1991-94: research fellow and lector at the University of Salzburg
1991: Universita „La Sapienzia“ Roma, Inst. of Biochemistry
CURRENT AFFILIATIONS 
Scientific societies: Intern. Soc. Dev. Biol., FASEB, AAAS, Intern. Soc. Hyaluronan Sciences - ISHAS, Intern. Soc. Stem Cell Research – ISSCR, ÖGGG
Founder and Vice-President of Austrian Scientists and Scholar in North America-ASCINA
Editor, Gerontology, Karger
Editorial Board Member, Open Tissue Eng. & Regen. Medicine, Open Longevity Science, Biogeronotology, Stem Cell Discovery, World Journal of Stem Cells
Scientific Advisory Board/Austrian Ministery for Health and Family Affairs, Commission for Genetic Engineering (2008-2012)
SCIENTIFIC EDUCATION
2004-September: tenure (section head; Austrian Academy of Sciences) 
2004-January: Habilitation DEVELOPMENTAL BIOLOGY (Univ. Innsbruck) Univ. Doz. 
2001-2002: staff scientist at NIH, NIDDK, Bethesda Maryland, USA
2000-October: Habilitation BIOCHEMISTRY (Univ. Salzburg) Univ. Doz. 
1999: NIH: Pathology of Genetically Engineered Mice
1998: University of Graz: Transgenic Mouse Models 
1994-June: Dr. rer. nat. CHEMISTRY (Univ. Vienna)
1993: NIOB Utrecht: Development Biology of Amphibians
1993: University of Newcastle: In situ Hybridization
1992: MPI Frankfurt: Xenopus laevis oocyte injection
1991: University of Oxford, Embryology of Xenopus laevis
1991-April: Mag. rer. nat. CHEMISTRY (Univ. Vienna)
1989-91: Institute of Molecular Biology, Austrian Academy of Sciences, Salzburg 
1985-89: Chemistry, University of Vienna
1984-85: Genetics, University of Salzburg
CAREER RELATED ACTIVITIES:
2007-: Member of the Editorial Board: Open Longevity Sciences, The Open Tissue Eng. & Regen. Medicine, Biogerontology
2007- Section editor to Gerontology, Karger
2002: Cofounder of ASCINA – Austrian Scientists and Scholars in North America 
2005-2008: Editor to Experimental Gerontology, Elsevier 
 
SCIENTIFIC CARREER
1989-1991:     Institute of Molecular Biology of the Austrian Academy of Sciences, Salzburg, chair: Prof. Dr. Günther Kreil, diploma thesis: Isolation and Characterization of Molecular Markers Relevant During Early development of Xenopus laevis. cDNA-Cloning (generation of cDNA libraries and isolation of of unique cDNAs with the aid of nucleic acid hybridization), DNA sequencing (dideoxy- as well as Maxam-Gilbert-method); in parallel to Northern-blot analysis, in-situ-hybridization using histological sections
Mar-Sept. 1991: Universita di Roma „La Sapienza“: Inst. of Biochemistry, Prof.a D. Barra, Prof. M. Simmaco: Isolation of cDNAs encoding bioactive peptide precursors from frog skin: in addition to basal molecular biological techniques, HPLC/FPLC and sequencing of proteins by automated Edman degradation
1991-1994:     Univ. of Salzburg, Institute for Genetics and Developmental Biology: Prof. Klaus Richter, Ph.D thesis: Isolation of Molecular Markers and Analysis of Inductive Processes during the Embryogenesis of Xenopus laevis. Optimization of subtractive hybridization in order to isolate a large number of novel molecular markers and further detailed analysis by whole mount in situ hybridization. Since no education in amphibian developmental biology could be attended in Salzburg, I visited several laboratories of reknown scientists, who kindly shared their expertise regarding embryological techniques: Univ. of Oxford, Prof. J. Slack; NIOB Utrecht, Prof. A. Durston; MRC London/Univ. Newcastle, D. Wilkinson
1994-2001:     Institute of Molecular Biology, Austrian Academy of Sciences, Head: Prof. G. Kreil, postdoctoral scientist: biochemical analysis of hyaluronan-degrading enzymes; bioinformatics (1994-1998: system administrator of the institute, analysis of DNA- and protein sequences (together with Dr. H. Flöckner, CAME Salzburg), extramural funding: FEBS, Boehringer-Ingelheim, Jubiläumsfond der Österr. Nationalbank, FWF; collaboration with Dr. U. Mayer (MPI-Martinsried)
(1997-2001) group leader: independant research team within the laboratory of Prof. G. Kreil: Investigation of the Functional Roles of Hyaluronan during Early Development of X. laevis; together with Prof. G. Kreil: analysis of bioactive peptide hormones
2001-2002:    staff scientist at National Institutes of Health: Inst. of Child Health and Development, Laboratory of Molecular Genetics, Section Vertebrate Development: transgenic approaches, functional genomics and microarrays, signalling pathways during early ectodermal differentiation
2002-:     PI/section head: Research Institute for Aging Research, Extracellular Matrix Research, APART Fellow, Burgen Scholar of the Academia Europeae, Editor for international journals, editorial board member of international journals, invitation to EU study sections, many invited lectures, applicant of EC research projects, co-organizer of scientific meetings and conferences, lecturer and supervisor in university education and training courses, international research cooperations
 
AWARDS/
Diploma thesis award of the University of Vienna (1991)
Best of Biotechnology Award, Salzburg/Vienna 2001
Christian-Doppler-Award 2002: Salzburg
Burgen Scholar of the Academia Europaea (2003)
Invited Life Member of the Internat. Society for Hyaluronan Sciences (ISHAS) (2004)
Werner Welzig Award of the Austrian Academy of Sciences 2005
EXTRAMURAL FUNDS
FEBS fellowship (1993)
Fellowship of the Boehringer-Ingelheim Science Foundation (1994)
Jubilee Fund of the Austrian National Bank (1997-1999): Generation of Hyal2-deficient mice
Austrian Science Foundation (FWF)(13001BIO) (1998-2001): The role of hyaluronic acid during development of Xenopus laevis (1.5MioATS)
APART: Austrian Academy of Sciences (2002-2005) (160.000€)
Jubilee Fund of the Austrian National Bank (2003-2005): Characterization of the early phase of atherosclerosis development (75.000€) 
Austrian Science Foundation (FWF) (2004-2007): „Proliferation, Differentiation and Cell Death during Cellular Aging – Extracellular Matrix Aging“ (FSP S9309) 225.000€
Austrian Research Agency FFG: (2007)“ Tendon Healing” joint project with ABT – Salzburg (75.000€/a)
Jubilee Fund of the Austrian National Bank (2007-2009): Improving bone healing by means of tissue engineered implants derived from human mesenchymal stem cells (85.000€)
Austrian Science Foundation (FWF) (2008-2010): „Proliferation, Differentiation and Cell Death during Cellular Aging – Stem Cell Aging“ (FSP S9309) 250.000€ 
EU FP7 (2009-2014) VASCUBone, partner, 750.000€
Tyrolean Future Fund (2009-2012) Smart Implants, coodinator, 295.000€
Laura Bassi Center of Excellence –DIALIFE (2009-13 (16)) project partner, 250.000€
Austrian Science Foundation (FWF) (2010-2013) The role of mesenchymal stem cells in the therapy of osteoarthritis; PI Reinhold Erben, Univ. Veterinary Medicine Vienna; GL co-applicant.
Herzfelder’sche Familienstiftung (2012-2013) Enkephalin, a key regulator of MSC stemness (20.000€)
ORGANIZATION AND INITIATIVES
1999-2000: Seminar series together with Landeshypothekenbank Salzburg und Salzburger Ärztekammer im Romanischen Keller, Salzburg: „Medizin der Zukunft“ (Initiative&Organization)
2003: ASCINA 2003 Harvard Medical School, Boston MA (Initiative&Coordinator/Leading Chairman)
2004-: subcoordinator of the joint research project “"Proliferation, Differentiation and Cell Death during Cellular Aging“  granted by the Austrian Science Fund FWF, FSP 093
2005: ASCINA 2005 Austrian Academy of Sciences, Vienna (Initiative & Organisation)
2006: National Scientific Committee FEBS2007 Congress (Vienna)
2008/9/10/11/12: ASCINA Young Scientists Award (together with BMWF)
2009: Member of the Scientific Advisory Board BioNanoMed 2009, Krems
2010: Member of the Scientific Advisory Board ECOPRAM 2010 Milano
2011: IAGG Bologna, session organizer and chair: Regenerative Medicine and Stem Cells in Biogerontology
2012: Member of the scientific advisory board: International conference TERMIS 2012, Vienna; ECOPRAM 2012 Istanbul
2012: organizer and chair Successful Aging 2012, Innsbruck
SHORT LIST POSITIONS
2008: Secundo loco, Professor for Molecular Regenerative Medicine, Paracelsus Medical University Salzburg, Austria
2009: Secundo loco, Professor for Molecular Biology, Medical University Graz, Austria
2010: offer of W3 Endowed Siebeneicher-Professor for Regenerative Medicine, Univ. Heidelberg
2012: Tertio loco, Professor for Experimental and Clinical Stem Cell Therapy, Paracelsus Medical University Salzburg, Austria

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