Rafal Koziel

Rafal Koziel was born in 1978 in Poland. He graduated at the Wroclaw University of Technology , Wroclaw, Poland at the Department of Biochemistry, where his main activity was focused on mutagenesis and protein purification. In 2002 he obtained master degree with the specialization “Molecular Biotechnology and Genetic Engineering” at the same university. In 2007 he obtained Ph.D. degree in biochemistry at the Nencki Institute of Experimantal Biology, Warsaw, Poland, Department of Biochemistry at the Laboratory of Bioenergetics and Biomembranes where he worked on the role of mitochondria and mitochondrial energy metabolism in calcium signaling, cell cycle regulation and viability of human cell lines.
In 2008 he joined the group of Molecular and Cell Biology at the Institute for Biomedical Aging Research, Innsbruck, Austria where he has been involved in several projects related to the role of mitochondria and reactive oxygen species (ROS) in cellular senescence and human aging. His main projects focus on the role of ROS generating enzymes, NADPH oxidases (Nox), and the role of autophagy and mitochondrial-specific form of autophagy (mitophagy) in cell metabolism, cellular senescence and organismal aging. Additionally, Dr. Koziel is involved in many other projects including the mechanisms by which protein restriction affects cellular lifespan or the cross-talk between mitochondria and proteasome activity in human skin aging.


E-Mail: Rafal.Koziel@uibk.ac.at

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