Sandbichler Adolf Michael Dr. 

Adress:
Institut für Zoologie
Universität Innsbruck
Technikerstr. 25
6020 Innsbruck
Österreich

Room: 6/20
Phone: +43 512 507-51868
E-Mail: adolf.sandbichler@uibk.ac.at

twitter.com/ASandbichler

Current research

I am interested in the influence of environmental stress such as osmotic changes, low oxygen or nutrient availability on the acclimation and homeostasis of primary cells and cell lines. One aim is the exact characterization of reactive oxygen species (ROS) emergence in response to hypoxic stress at the interface of cell metabolism and redox balance. I study these cell physiological responses with modern live cell imaging and measurement methods.

For more details, see:

• Circadiane Rhythmik
• Hypoxie Adaptation
• Live Cell Imaging, Signal und Daten Analyse
• MACI - Metabolic Analysis Cluster Innsbruck

Here you can find my portrait in the context of "350 Years University of Innsbruck, Together we are Uni" (September 2019).

Courses

in the master program Molecular Cell and Developmental Biology (MolZEB).

• Wintersemester (Oktober):
  Wahlmodul 9: Zellbiologie II: Zellhomöostase (7,5 ECTS-AP, 5 SSt)
  719515 Zellhomöostase (SE)
  719516 Zellhomöostase (UE)

• Sommersemester (März):
  Wahlmodul 7: Live Cell Imaging (7,5 ECTS-AP, 5 SSt)
  719301 Live Cell Imaging (VO)
  719302 Live Cell Imaging (UE)

Administrative work

Since 2006, I have been the Disability Representative for the scientific staffin the Works Council of the University of Innsbruck.

Curriculum vitae

 

Projects

 

 

• Non-canonical redox response to neuronal Interleukin-6 signaling - NeuREDOX, Tiroler Wissenschaftsförderung, 2023-2024

• Reactive Oxygen Species and their role in the interaction between Circadian Clock and Hypoxic Signaling Pathway, Forschungsförderungsmittel der Nachwuchsförderung  der Universität Innsbruck 2016-2018

• Anpassung von Kiemenepithelzellen an osmotische Veränderungen, Tiroler Wissenschaftsfonds (TWF), 2005-2008

• Reactive Oxygen Species and their role in the interaction between Circadian Clock and Hypoxic Signaling Pathway, Forschungsförderungsmittel der Nachwuchsförderung 2015 der Universität Innsbruck

• Anpassung von Kiemenepithelzellen an osmotische Veränderungen, Tiroler Wissenschaftsfonds (TWF), 2005

 

Publications

Contributions in books / journals

Journal article (original work)

 

• Drechsel, V.; Schneebauer, G.; Sandbichler, A.M.; Fiechtner, B.; Pelster, B. (2022): Oxygen consumption and acid secretion in isolated gas gland cells of the European eel Anguilla anguilla.In: Journal of Comparative Physiology B: Biochemical, Systemic, and environmental physiology 192, S. 447 - 457. (DOI) (Weblink)
• Srut, M.; Peer, B.; Fiechtner, B.; Egg, M.; Sandbichler, A.M.; Höckner, M. (2022): Aging Cell Culture - Genetic and Metabolic Effects of Passage Number on Zebrafish Z3 Cells.In: Cellular Physiology and Biochemistry 56, S. 50 - 65. (Volltext) (DOI) (Weblink)
• Thöni, V.; Mauracher, D.; Ramalingam, A.; Fiechtner, B.; Sandbichler, A.M.; Egg, M. (2022): Quantum based effects of therapeutic nuclear magnetic resonance persistently reduce glycolysis.In: iScience 25/12, Nr. 105536. (Volltext) (DOI) (Weblink)
• Badstöber, J.; Gachon, C.M.M.; Ludwig-Müller, J.; Sandbichler, A:M.; Neuhauser, S. (2020): Demystifying biotrophs: FISHing for mRNAs to decipher plant and algal pathogen-host interaction at the single cell level.In: Scientific Reports 10/1, No. 14269. (DOI) (Weblink)
• Dikova, V.; Vorhauser, J.; Geng, A.; Pelster, B.; Sandbichler, A.M. (2020): Metabolic interaction of hydrogen peroxide and hypoxia in zebrafish fibroblasts.In: Free Radical Biology & Medicine 152, S. 469 - 481. (DOI) (Weblink)
• Kaehler, K.; Seitter, H.; Sandbichler, A.M.; Tschugg, B.; Obermair, G.J.; Stefanova, N.; Koschak, A. (2020): Assessment of the Retina of Plp-α-Syn Mice as a Model for Studying Synuclein-Dependent Diseases.In: Investigative Ophthalmology & Visual Science 61/6, No. 12. (DOI) (Weblink)
• Oliva, R.; Jansen, B.; Benscheidt, F.; Sandbichler, A.M.; Egg, M. (2019): Nuclear magnetic resonance affects the circadian clock and hypoxia-inducible factor isoforms in zebrafish.In: Biological Rhythm Research 50/5, S. 739 - 757. (Volltext) (DOI) (Weblink)
• Sandbichler, A.M.:; Jansen, B.; Peer, B.A..; Paulitsch, M.; Pelster, B.; Egg, M. (2018): Metabolic Plasticity Enables Circadian Adaptation to Acute Hypoxia in Zebrafish Cells.In: Cellular Physiology and Biochemistry 46/3, S. 1159 - 1174. (Volltext) (DOI)
• Egg, M.; Paulitsch, M.; Ennemoser, Y.; Wüstenhagen, A.; Schwerte, T.; Sandbichler, A. M.; Fiechtner, B.; Köblitz, L.; Prem, C.; Pelster, B. (2014): Chronodisruption increases cardiovascular risk in zebrafish via reduced clearance of senescent erythrocytes.In: Chronobiology International 31/5, S. 680 - 689. (DOI)
• Leis, S.; Dresch, P.; Peintner, U.; Fliegerova, K.; Sandbichler, A.M.; Insam, H.; Podmirseg, Sabine Marie (2014): Finding a robust strain for biomethanation: anaerobic fungi (Neocallimastigomycota) from the Alpine ibex (Capra ibex) and their associated methanogens.In: ANAEROBE 29, S. 34 - 43. (DOI) (Weblink)
• Sandbichler, A.M.; Aschberger, T.; Pelster, B. (2013): A Method to Evaluate the Efficiency of Transfection Reagents in an Adherent Zebrafish Cell Line.In: BioResearch Open Access 2/1, S. 20 - 27. (DOI) (Weblink)
• Egg, M.; Tischler, A.; Schwerte, T.; Sandbichler, A.; Folterbauer, C.; Pelster, B. (2012): Endurance exercise modifies the circadian clock in zebrafish (Danio rerio) temperature independently.In: Acta Physiologica 205/1, S. 167 - 176. (DOI) (Weblink)
• Sandbichler, A.M.; Egg, M.; Schwerte, T.; Pelster, B. (2011): Claudin 28b and F-actin are involved in rainbow trout gill pavement cell tight junction remodeling under osmotic stress.In: Journal of Experimental Biology 214/9, S. 1473 - 1487. (DOI)
• Sandbichler, A.M.; Farkas, J.; Salvenmoser, W.; Pelster, B. (2011): Cortisol affects tight junction morphology between pavement cells of rainbow trout gills in single-seeded insert culture.In: Journal of Comparative Physiology B: Biochemical, Systemic, and environmental physiology 181/8, S. 1023 - 1034. (DOI)
• Kopp, R.; Schwerte, T.; Egg, M.; Sandbichler, A.M.; Egger, B.; Pelster, B. (2010): Chronic reduction in cardiac output induces hypoxic signaling in larval zebrafish even at a time when convective oxygen transport is not required.In: PHYSIOLOGICAL GENOMICS 42a, S. 8 - 23. (DOI)
• Martien, R.; Loretz, B.; Sandbichler, A.M.; Bernkop-Schnürch, A. (2008): Thiolated chitosan nanoparticles: transfection study in the Caco-2 differentiated cell culture.In: Nanotechnology 19, S. 1 - 9.
• SANDBICHLER, AM.; PELSTER, B. (2004): Acid-Base Regulation in Isolated Gill Cells of the Goldfish (Carassius auratus).In: Journal of Comparative Physiology B: Biochemical, Systemic, and environmental physiology 174/8, S. 601 - 610.

 

Journal Article (Review)

 

• Sandbichler, A.M.; Höckner, M. (2016): Cadmium Protection Strategies-A Hidden Trade-Off?In: International Journal of Molecular Sciences 17/1, No. 139. (DOI) (Weblink)

 

Journal article (meeting abstract)

 

• Sandbichler, Adolf Michael; Selbenbacher, Josef (2020): Comparative Redox-active Properties of Asparagine Metabolism in Zebrafish and Mouse Fibroblasts.In: Free Radical Biology & Medicine 159/1, S. S74. (DOI) (Weblink)
• Kähler, K; Seitter, H; Sandbichler, A; Obermair, G; Stefanova, N; Koschak, A (2018): Morphology of the Neuroretina in Multiple System Atrophy: does the Pathology of MSA manifest in the retina?In: Investigative Ophthalmology & Visual Science 59/9, No. 1884.
• Sandbichler, A. M.; Schwerte, T.; Pelster, B. (2009): Cortisol-dependent remodelling of tight junction claudin 28b and cortical F-actin in cultured gill epithelia of rainbow trout.In: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY 154/1 (Supplement 1), S. S29.
• Aigner, M.; Botta, M.; Sandbichler, A.; Salvenmoser, W.; Egger, B.; Rieger, R.; Gschwentner, R. (2005): Development of a basal medium for primary cell culture of marine flatworms.In: Berichte des Naturwissenschaftlich-Medizinischen Vereins in Innsbruck 16, S. 20.
• Sandbichler, AM.; Egg, M.; Pelster, G.B. (2005): Osmolarity-induced changes in trout gill epithelial cells on permeable supports.In: COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY 141/Supplement 1, S. 197.

 

Other publications

electronic publication (preprint)

 

• Badstöber, J.; Gachon, C.M.M.; Sandbichler, A.; Neuhauser, S. (2019): Biotrophic interactions disentangled: In-situ localisation of mRNAs to decipher plant and algal pathogen – host interactions at single cell level. (DOI) (Weblink)

Presentations

Presentations at congresses, conferences, etc.

Conference lecture (Invited Plenary / Keynote Lecture)

 

• Vortragende/r: Neuhauser, S. Co-AutorInnen: Badstöber, J.; Loacker, A.; Ciaghi, S.; Harikrishnan, S.; Sandbichler, A. M.; Kirchmair, M.; Gachon, MM C.: Biotrophic interactions untangled: In-situ localization of mRNAs is a powerful tool to study pathogen – host interactions at the single cell level. SAMS-Algal Research for Policy-Making and Biotech, Oban, 15.05.2018. (Weblink)

 

Conference presentation (by personal invitation)

 

• Vortragende/r: Neuhauser, Sigrid Co-AutorInnen: Kirchmair, Martin; Ciaghi, Stefan; Badstöber, Julia; Schwelm, Arne; Ludwig Müller, Jutta; Sandbichler, Adolf M.; Gachon, Claire: Understanding phytomyxid-host interactions by combining transcriptomics with in-situ transcript visualisation. 38th Annual Meeting of the German Society for Protozoology, Wien, 21.02.2019.

 

• Vortragende/r: Egg, M. Co-AutorInnen: Sandbichler, A.: Linking oxygen to time: The impact of oxygen availability on the circadian clock in zebrafish. The 29th Conference of the International Society for Chronobiology (ISC), Suzhou, 26.10.2016. (Weblink)

 

Conference presentation (on submission / registration)

 

• Vortragende/r: Hobmayer, B. Co-AutorInnen: Eder, M.-K.; Achrainer, M.; Grüner, K.; Sandbichler, A.; Salvenmoser, W.; Cazet, J.; Juliano, C.E.: A Hydra Claudin cell-cell contact protein is involved in epithelial tissue dynamics, regeneration, and osmoregulation.Cnidofest 2022: Second Biennial Cnidarian Model Systems Meeting, Davis, 09.09.2022. (Weblink)
• Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Wille, V.; Selbenbacher, J.: Asparagine vulnerability of redox metabolism in zebrafish and mouse fibroblasts.2nd FEBS Workshop Ageing & Regeneration 2022, Mutters, 04.07.2022. (Weblink)
• Vortragende/r: Hobmayer, B. Co-AutorInnen: Eder, M.K.; Achrainer, M.; Grüner, K.; Sandbichler, A.; Salvenmoser, W.: A Hydra Claudin cell-cell contact protein is involved in epithelial tissue dynamics, regeneration, and osmoregulation.MARISTEM COST Action - Final Meeting, Padova, 20.10.2021. (Weblink)
• Vortragende/r: Egg, M. Co-AutorInnen: Schwerte, T.; Sandbichler, A.M.; Pelster, B.: Linking time to oxygen: The cross-talk between the Circadian Clock and the Hypoxic Signaling Pathway.Society for Experimental Biology Annual Meeting 2014, Manchester, 03.07.2014. (Weblink)
• Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Nagy, J.; Egg, M.: Differential hypoxic response of the circadian clock: attenuation versus phase shift.Society for Experimental Biology Annual Meeting 2014, Manchester, 03.07.2014. (Weblink)
• Vortragende/r: Leis, S. Co-AutorInnen: Dresch, P.; Peintner, U.; Fliegerová, K.; Sandbichler, A.M.; Insam, H.; Podmirseg, Sabine Marie: Isolation and identification of anaerobic fungi (Neocallimastigomycota) from an alpine herbivore, the capricorn (Capra ibex).8th International Symposium on Anaerobic Microbiology (ISAM8), Innsbruck, 13.06.2013.
• Vortragende/r: Sandbichler, A.: Osmolarity-induced changes in trout gill epithelial cells on permeable supports.SEB Annual Main Meeting 2005, Barcelona, 11.07.2005.

 

Lecture at expert conference

 

• Vortragende/r: Egg, M. Co-AutorInnen: Oliva, R.; Benscheidt, F.; Sandbichler, A.M.: Wirkung der MBST Kernspinresonanztherapie (MBST NMR) auf die Innere Uhr und den Sauerstoff-Signalweg. Anwendertagung / Conference: Therapie par resonance magnetique nucleaire, St. Chamond, Lyon, 19.10.2017.

 

Poster presentation

 

• Vortragende/r: Thöni, V. Co-AutorInnen: Dimova, E.Y.; Kietzman, T.; Sandbichler, A.M.; Egg, M.: Water proton resonances reset the circadian clock in mammalian cells. GRC Quantum Biology Gordon Research Conference, Galveston (Texas), 20.03.2023. (Weblink)
• Vortragende/r: Sana, F. Co-AutorInnen: Kalpachidou, T.; Kummer, K.; Sandbichler, A.M.; Kress, M.: Effects of Interleukin signaling on metabolism and redox balance in the human neuroblastoma cell line SH-SY5Y.8th CMBI Meeting Innsbruck 2022, Igls, 30.09.2022. (Weblink)
• Vortragende/r: Thöni, Viktoria Co-AutorInnen: Mauracher, D.; Sandbichler, A.M.; Egg, M.: Therapeutic Nuclear magnetic resonance redirects the metabolism of NIH-3T3 cells.XVII European Biological Rhythms Society (EBRS 2022), Zürich, 25.07.2022. (Weblink)
• Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Wille, V.; Selbenbacher, J.: Asparagine vulnerability of redox metabolism in zebrafish and mouse fibroblasts.2nd FEBS Workshop Ageing & Regeneration 2022, Mutters, 04.07.2022. (Weblink)
• Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Wille, V.; Vorhauser, J.: Hypoxia in mouse and zebrafish fibroblasts: a differentail role of peroxisomes in cellular redox balance.Society for Redox Biology and Medicine 28th Annual Conference (SfRBM 2021), Indianapolis (online), 15.11.2021. (Weblink)
• Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Selbenbacher, J.; Wille, V.: Comparative Redox-active Properties of Asparagine Metabolism in Zebrafish and Mouse Fibroblasts.Society for Redox Biology and Medicine 27th Annual Conference (SfRBM 2020), Savannah, 19.11.2020. (Weblink)
• Vortragende/r: Badstöber, J; Gachon, CMM; Sandbichler, A; Neuhauser, S: Biotrophic interactions disentangled: In-situ localisation of mRNAs to decipher plant and algal pathogen - host interactions at single cell level.Kick-off Meeting Life & Health Science Cluster Tirol, Innsbruck, 04.12.2018. (Weblink)
• Vortragende/r: Dikova, V. Co-AutorInnen: Vorhauser, J.; Pelster, B.; Sandbichler, A.M.: Hydrogen Peroxide under Hypoxia/Reoxygenation in Zebrafish Fibroblasts.7th Annual CMBI Meeting Innsbruck, Vill, 20.09.2018. (Weblink)
• Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Sandbichler, Adolf; Obermair, Gerald; Stefanova, Nadia; Koschak, Alexandra: The Neuroretina in Multiple System Atrophy: Morphological Implications of Plp-α-Syn Mice.47th Annual Meeting of the Society for Neuroscience, Washington D.C., 14.11.2017. (Weblink)
• Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Sandbichler, Adolf; Obermair, Gerald; Stefanova, Nadia; Koschak, Alexandra: The neuroretina in multiple system atrophy: morphological implications of Plp-α-Syn mice. European Retina Meeting 2017 (ERM), Paris, 06.10.2017. (Weblink)
• Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Sandbichler, Adolf; Obermair, Gerald; Stefanova, Nadia; Koschak, Alexandra: Does the Pathology of Multiple System Atrophy manifest in the Neuroretina?23nd Scientific Symposium of the Austrian Pharmacological Society (APHAR), Innsbruck, 29.09.2017. (Weblink)
• Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Sandbichler, Adolf; Obermair, Gerald; Stefanova, Nadia; Koschak, Alexandra: Does the Pathology of Multiple System Atrophy manifest in the Neuroretina?9th ÖGMBT Annual Meeting & 8th Life Science Meeting Innsbruck, Innsbruck, 26.09.2017.
• Vortragende/r: Lamberti, G. Co-AutorInnen: Laschober, G.; Sopper, S.; Sandbichler, A.M.; Trajanoski, Z.: Metabolic characterization of human T-cells during differentiation.9th ÖGMBT Annual Meeting & 8th Life Science Meeting Innsbruck, Innsbruck, 26.09.2017. (Weblink)
• Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Vorhauser, J.; Geng, A.: Peroxisomes and their role in cellular redox balance in zebrafish fibroblasts.9th ÖGMBT Annual Meeting & 8th Life Science Meeting Innsbruck, Innsbruck, 26.09.2017. (Weblink)
• Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Sandbichler, Adolf; Stefanova, Nadia; Koschak, Alexandra: Does the Pathology of Multiple System Atrophy manifest in the Neuroretina?15th Austrian Neuroscience Association (ANA), Klosterneuburg, 25.09.2017. (Weblink)
• Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Tschugg, Bettina; Sturm, Edith; Sandbichler, Adolf M.; Stefanova, Nadia; Koschak, Alexandra: The Neuroretina in Multiple System Atrophy.5th Annual SFB Meeting 2016, Vill, 30.11.2016. (Weblink)
• Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Tschugg, Bettina; Sturm, Edith; Sandbichler, Adolf M.; Stefanova, Nadia; Koschak, Alexandra: The Neuroretina in Multiple System Atrophy.22nd Scientific Symposium of the Austrian Pharmacological Society (APHAR), Wien, 09.09.2016. (Weblink)
• Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Tschugg, Bettina; Sturm, Edith; Sandbichler, Adolf M.; Stefanova, Nadia; Koschak, Alexandra: The Neuroretina in Multiple System Atrophy: Atrophy Morphological and Functional Aspects in Plp-α-Syn Mice.10th FENS Forum of Neuroscience, Kopenhagen, 06.07.2016. (Weblink)
• Vortragende/r: Kaehler, Kathrin Co-AutorInnen: Seitter, Hartwig; Tschugg, Bettina; Sturm, Edith; Sandbichler, Adolf M.; Stefanova, Nadia; Koschak, Alexandra: Retinal immunoreactivity in a mouse model of multiple system atrophy.6th Annual CMBI Meeting Innsbruck, Gnadenwald, 04.03.2016. (Weblink)
• Vortragende/r: Kaehler, K. Co-AutorInnen: Seitter, H.; Knoflach, D.; Sturm, E.; Sandbichler, A.; Stefanova, N.; Koschak, A.: Retinal pathomorphology in a mouse model of multiple system atrophy.European Retina Meeting 2015, Brighton, 01.10.2015. (Weblink)
• Vortragende/r: Muik, M. Co-AutorInnen: Gomez-Brandon, M.; Sandbichler, A.M.; Insam, H.; Wett, B.; Podmirseg, Sabine Marie: Characterization of anammox granules from a full-scale WWTP by microscopic techniques and a novel particle tracking method.8th International Symposium on Anaerobic Microbiology (ISAM8), Innsbruck, 12.06.2013.
• Vortragende/r: Sandbichler, A.M. Co-AutorInnen: Scheidnagl, S.; Selcuk, D.; Rainer, D.; Pelster, B.; Egg, M.: Mitochondrial plasticity in zebrafish fibroblasts exposed to hypoxia.Mitochondrial Trafficking and Function in Health and Disease, Boston, 25.06.2012. (Weblink)
• Vortragende/r: Schredelseker, T. Co-AutorInnen: Schneebauer, G.; Sandbichler, A.M.; Meyer, D.; Schwerte, T.: Analysis of mechanisms to survive oxygen deprivation in vivo and in vitro.Swiss and Upper Rhine Valley (SURV) Zebrafish Meeting 2012 (Zebrafish 2012), Basel, 13.04.2012. (Weblink)
• Vortragende/r: Sandbichler, A.; Schwerte, T.; Pelster, B.: Cortisol-dependent remodelling of tight junction claudin 28b and cortical F-actin in cultured gill epithelia of rainbow trout.26th ESCPB Congress of the new European Society for Comparative Physiology and Biochemistry, Innsbruck, 06.09.2009.
• Vortragende/r: Sandbichler, AM.; Schwerte, T.; Pelster, B.: Osmolarity-dependent remodelling of barrier properties in trout gill cell layers.4th Annual Meeting of the Center of Molecular Biosciences (CMBI), Igls, 28.09.2007.
• Vortragende/r: Aigner, M.; Botta, M.; Sandbichler, A.; Salvenmoser, W.; Egger, B.; Rieger, R.; Gschwentner, R.: Development of a basal medium for primary cell culture of marine flatworms.10th International Symposium on Flatworm Biology (ISFB 2006), Innsbruck, 29.07.2006.
• Vortragende/r: Sandbichler, A.; Egg, M.; Pelster, B.: The influence of apical hypoosmotic stress on the expression of cytoskeletal components in trout gill epithelial cells. 7th International Congress on the Biology of Fish (ICBF VII), St. John’s, 18.07.2006.
• Vortragende/r: Sandbichler, A.; Egg, M.; Pelster, B.: Transcriptional response to apical osmotic stress in trout gill epithelial cells.2nd Annual Meeting of the Center for Molecular Biosciences (CMBI), Vill, 30.09.2005.
• Vortragende/r: Sandbichler, A.; Egg, M.; Pelster, B.: Transcriptional response to apical osmotic stress in trout gill epithelial cells.SEB Annual Main Meeting 2005, Barcelona, 11.07.2005.