Lydia completed her BSc in Sport and Exercise Sciences at the University of Birmingham in 2014 and was awarded an MSc in Human and Applied Physiology, from Kings College London, in 2016. She then joined Bangor University, as a PhD researcher, in the autonomic cardiovascular laboratory. Lydia’s doctoral research examined the adaptation of the autonomic nervous system during chronic high-altitude hypoxia, with a specific focus on baroreflex control of blood pressure. She has taken part in research expeditions to the Himalaya and the Peruvian Andes, as part of the international research collaboration Global REACH, where she has collected data in lowland and high-altitude natives. Lydia has presented at several international conferences and scientific symposia and was awarded the Early Career Researcher Prize at the Physiological Society’s Extreme Environmental Physiology conference.
Lydia’s primary research interest is how the autonomic nervous system controls cardiovascular function, specifically the control of blood pressure by the arterial baroreflex mechanism. Lydia is interested in how arterial baroreflex function is altered during chronic hypoxic exposure, and its interation with other neural reflexes, including those originating from the peripheral oxygen sensors and pressure sensitive receptors in the pulmonary arteries. Lydia is also interested in the influence of sex on the regulation of blood pressure at high altitude, in both Lowland and highland natives.
- VO Leistungsphysiologie
- VO Stoffwechsel
- VU Angewandte Leistungsphysiologie
- SE Problemanalyse und Forschung in der Trainingswissenschaft
Simpson et al., (2019). Baroreflex control of sympathetic vasomotor activity and resting arterial pressure at high altitude: insight from Lowlanders and Sherpa. Journal of Physiology. https://doi.org/10.1113/JP277663
Simpson et al., (2020). Evidence for a physiological role of pulmonary arterial baroreceptors in sympathetic neural activation in healthy humans. Journal of Physiology. https://doi.org/10.1113/JP278731
Simpson et al., (2021). Global REACH 2018: Andean highlanders, chronic mountain sickness and the integrative regulation of resting blood pressure. Experimental Physiology. https://doi.org/10.1113/EP088473
Simpson et al., (2021). A sympathetic view of blood pressure control at high altitude: new insights from microneurographic studies. Experimental Physiologyhttp://dx.doi.org/10.1113/EP089194
Lord et al., (2020). The influence of barosensory vessel mechanics on the vascular sympathetic baroreflex: Insights into aging and blood pressure homeostasis. American Journal of Physiology - Heart and Circulatory Physiology. https://doi.org/10.1152/ajpheart.00265.2020
Berthelsen et al., (2020). Highs and lows of sympathetic neurocardiovascular transduction: influence of altitude acclimatization and adaptation. American Journal of Physiology- Heart and Circulatory Physiology. https://doi.org/10.1152/ajpheart.00364.2020
Wakeham et al., (2019). Upward resetting of the vascular sympathetic baroreflex in middle-aged male runners. American Journal of Physiology-Heart and Circulatory Physiology. https://doi.org/10.1152/ajpheart.00106.2019
Busch et al., (2020). Muscle sympathetic reactivity to apneic and exercise stress in high-altitude Sherpa. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. https://doi.org/10.1152/ajpregu.00119.2019
Braz et al., (2014). Influence of muscle metaboreceptor stimulation on middle cerebral artery blood velocity in humans. Experimental Physiology. https://doi.org/10.1113/expphysiol.2014.081687
Busch et al., (2017). Chemoreflex Mediated Arrhythmia during Apnea at 5050m in Low but not High Altitude Natives. Journal of Applied Physiology. https://doi.org/10.1152/japplphysiol.00774.2017