Eduard Stefan, Ph.D.

Eduard Stefan, Ph.D.

Privatdozent Dr.rer.nat.
Head of the Institute

 

Institute of Biochemistry
University of Innsbruck
Room no. L.03.042

Center for Chemistry and Biomedicine (CCB) Innrain 80-82, 6020 Innsbruck / Austria
Phone: +43 512 507 - 57531 | Fax: +43 512 507 - 57599
Email: eduard.stefan@uibk.ac.at

Research Interest

  • Analyses of binary and more dimensional kinase interactions in vivo
  • Compartmentalized kinase signalling (PKA, RAF, MEK, GPCR)
  • Involvement of post-translational modifications (phosphorylation, ubiquitination, acetylation) in redirecting second messenger involved signal transmission
  • Drug discovery efforts involving oncokinases, transcription factors and GPCRs
  • Generation of unique cell-based reporter platforms to analyze dynamics of protein and cancer drug interactions

Recent Grant Support

Austrian Science Fund P30441 (2018-2021)
Austrian Science Fund P27606 (2015-2018)
Austrian Science Fund P22608 (2010-2015)
Tyrolean Science Fund
SFB-F44 (initial funding)

Scientific Team Members

Florian Enzler, M.S. - kinase interactions, drug discovery
Johanna Mayrhofer, M.S. - kinase interactions, drug discovery
Ruth Röck, M.S. - molecular interactions of oncoproteins, reporter platform
Omar Torres Quesada, Ph.D. - kinase regulated RNA binders
Christoph Schneider - kinase conformations